Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392097 | 0.87 | LPAR1 (0.52) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL7190020 | 0.86 | ALDH1A1 (0.37) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL2727565 | 0.86 | FAAH (0.43) | LPAR1LPAR2ENPP2CNR1ALDH1A1 | |
| SCHEMBL2687424 | 0.83 | EPHX2 (0.45) | LPAR1EPHX2CNR1ALDH1A1HPGD | |
| SCHEMBL9437697 | 0.81 | EPHX2 (0.54) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL29391868 | 0.81 | LPAR1 (0.48) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL9860855 | 0.80 | LPAR1 (0.67) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL9860844 | 0.80 | LPAR1 (0.67) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL29383764 | 0.80 | FAAH (0.55) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| Disodium Lauramido Mea SCHEMBL3697471 | 0.79 | FAAH (0.43) | LPAR1LPAR2ENPP2EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4734923-A1 | CLEANSING COMPOSITIONS COMPRISING DIVALENT SALTS | L'OREAL (FR) | 2026-05-06 | — | — | EP | claimed |
| US-20250090435-A1 | PRESERVATIVES FOR COSMETIC AND PHARMACEUTICAL COMPOSITIONS | SACHEM, INC. (US) | 2025-03-20 | — | — | US | claimed |
| US-20250009628-A1 | CLEANSING COMPOSITIONS COMPRISING DIVALENT SALTS | L'OREAL (FR) | 2025-01-09 | — | — | US | claimed |
| EP-4486289-A1 | COMPOSITIONS AND METHODS FOR CURLY HAIR | L'OREAL (FR) | 2025-01-08 | — | — | EP | claimed |
| WO-2025006412-A1 | CLEANSING COMPOSITIONS COMPRISING DIVALENT SALTS | L'OREAL (FR) | 2025-01-02 | — | — | WO | claimed |
| EP-4376798-A1 | PRESERVATIVES FOR COSMETIC AND PHARMACEUTICAL COMPOSITIONS | Sachem, Inc. (US) | 2024-06-05 | — | — | EP | claimed |
| WO-2023164280-A1 | COMPOSITIONS AND METHODS FOR CURLY HAIR | RUGHANI RONAK (US) | 2023-08-31 | — | — | WO | claimed |
| WO-2023009849-A1 | PRESERVATIVES FOR COSMETIC AND PHARMACEUTICAL COMPOSITIONS | SACHEM, INC. (US) | 2023-02-02 | — | — | WO | claimed |
| CN-122094649-A | Personal care compositions | — | 2026-05-26 | — | — | CN | disclosed |
| EP-4734923-A1 | CLEANSING COMPOSITIONS COMPRISING DIVALENT SALTS | L'OREAL (FR) | 2026-05-06 | — | — | EP | disclosed |
| US-20260109915-A1 | SILICONE AND SULFATE-FREE CONDITIONING SHAMPOO | L'OREAL (FR) | 2026-04-23 | — | — | US | disclosed |
| US-20260108445-A1 | CREAMY SILICONE AND SULFATE-FREE CONDITIONING SHAMPOO | L'OREAL (FR) | 2026-04-23 | — | — | US | disclosed |
| US-20260108440-A1 | Personal Care Compositions | COLGATE-PALMOLIVE COMPANY (US) | 2026-04-23 | — | — | US | disclosed |
| US-20260108443-A1 | Personal Care Compositions | COLGATE-PALMOLIVE COMPANY (US) | 2026-04-23 | — | — | US | disclosed |
| US-20220241179-A1 | CLEANSING COMPOSITIONS | L'OREAL (FR) | 2022-08-04 | — | — | US | disclosed |
| CN-114829561-A | Liquid pearlescent composition | 罗地亚经营管理公司 | 2022-07-29 | — | — | CN | disclosed |
| WO-2022146771-A1 | EFFERVESCENT SOLID DOSAGE FORM COMPOSITIONS CONTAINING ENVIRONMENTALLY SAFER ANTI-MICROBIAL COMPONENTS | CHEMLINK LABORATORIES, LLC (US) | 2022-07-07 | — | — | WO | disclosed |
| US-20220096338-A1 | COMPOSITIONS AND METHODS FOR STYLING HAIR | L'OREAL (FR) | 2022-03-31 | — | — | US | disclosed |
| WO-2022046520-A1 | COMPOSITIONS AND METHODS FOR CLEANSING KERATIN MATERIALS | L'OREAL (FR) | 2022-03-03 | — | — | WO | disclosed |
| US-20220062136-A1 | COMPOSITIONS AND METHODS FOR CLEANSING KERATIN MATERIALS | L'OREAL (FR) | 2022-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260108445-A1 | CREAMY SILICONE AND SULFATE-FREE CONDITIONING SHAMPOO | SMURF1, SGMS1, SGMS2 | LPAR1 223/4885LPAR2 209/4885ENPP2 2054/4885 |
| US-20250009628-A1 | CLEANSING COMPOSITIONS COMPRISING DIVALENT SALTS | DAGLB, DSG1, CUTA | LPAR1 146/4885LPAR2 174/4885ENPP2 3836/4885 |
| US-20250090435-A1 | PRESERVATIVES FOR COSMETIC AND PHARMACEUTICAL COMPOSITIONS | PLOD2, CUTA, PHOSPHO1 | LPAR1 736/4885LPAR2 604/4885ENPP2 1999/4885 |
| US-20260108440-A1 | Personal Care Compositions | PBDC1, PIEZO1, TRPC7 | LPAR1 600/4885LPAR2 508/4885ENPP2 1904/4885 |
| US-20220062136-A1 | COMPOSITIONS AND METHODS FOR CLEANSING KERATIN MATERIALS | KRT18, DSG1, SGMS1 | LPAR1 535/4885LPAR2 476/4885ENPP2 1144/4885 |
| US-20220241179-A1 | CLEANSING COMPOSITIONS | SMURF1, SMURF2, SGMS2 | LPAR1 418/4885LPAR2 457/4885ENPP2 1963/4885 |
| US-20220096338-A1 | COMPOSITIONS AND METHODS FOR STYLING HAIR | PIK3C3, PRKDC, FLNA | LPAR1 2206/4885LPAR2 2050/4885ENPP2 1847/4885 |
| US-20260109915-A1 | SILICONE AND SULFATE-FREE CONDITIONING SHAMPOO | SGMS1, SGMS2, SMURF1 | LPAR1 388/4885LPAR2 396/4885ENPP2 2735/4885 |
| US-20260108443-A1 | Personal Care Compositions | SMURF1, WASHC4, CUTA | LPAR1 859/4885LPAR2 893/4885ENPP2 1071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.