Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3088557 | 1.00 | GSR (0.50) | GSRCPB2GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL587916 | 0.98 | GSR (0.48) | GSRCPB2GNAI3GNAO1GNAI1 | |
| SCHEMBL855342 | 0.98 | GSR (0.52) | GSRCPB2GNAI3GNAO1GNAI1 | |
| SCHEMBL866977 | 0.98 | GSR (0.52) | GSRCPB2GNAI3GNAO1GNAI1 | |
| SCHEMBL1310240 | 0.96 | GSR (0.50) | GSRCPB2GNAI3GNAO1GNAI1 | |
| SCHEMBL1308683 | 0.96 | GSR (0.50) | GSRCPB2GNAI3GNAO1GNAI1 | |
| SCHEMBL1309450 | 0.96 | GSR (0.50) | GSRCPB2GNAI3GNAO1GNAI1 | |
| SCHEMBL1309368 | 0.96 | GSR (0.50) | GSRCPB2GNAI3GNAO1GNAI1 | |
| SCHEMBL2131918 | 0.96 | GSR (0.50) | GSRCPB2GNAI3GNAO1GNAI1 | |
| SCHEMBL1323618 | 0.96 | GSR (0.50) | GSRCPB2GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568985-A1 | RADIOPHARMACEUTICALS | Advancell Isotopes Pty Limited (AU) | 2025-06-18 | — | — | EP | disclosed |
| CN-119012914-A | Method for controlling parasitic plants | 味之素株式会社 | 2024-11-22 | — | — | CN | disclosed |
| CN-118496124-A | Preparation method of N-alpha- (9-fluorenylmethoxycarbonyl) -lysine-tert-butyl ester hydrochloride | 吉尔生化（上海）有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-115516044-B | Fluorescent dimer compounds useful as probes for detection of endogenous receptors | 斯特拉斯堡大学 | 2024-05-14 | — | — | CN | disclosed |
| WO-2024031155-A1 | RADIOPHARMACEUTICALS | AdvanCell Isotopes Pty Limited (AU) | 2024-02-15 | — | — | WO | disclosed |
| WO-2023195475-A1 | METHOD FOR CONTROLLING PARASITIC PLANTS | 味の素株式会社 | 2023-10-12 | — | — | WO | disclosed |
| EP-3683221-B1 | NOVEL CHLORIN E6 DERIVATIVE AND PHARMACEUTICALLY-ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | SHANGHAI BIOPHY BIOLOGICAL PHARMACEUTICAL CO LTD (CN) | 2023-06-28 | — | — | EP | disclosed |
| US-20230174480-A1 | FLUOROGENIC DIMER COMPOUND, USEFUL AS A PROBE FOR DETECTION OF ENDOGENOUS RECEPTORS | UNIVERSITE DE STRASBOURG (FR) | 2023-06-08 | — | — | US | disclosed |
| EP-4150009-A1 | FLUOROGENIC DIMER COMPOUND, USEFUL AS A PROBE FOR DETECTION OF ENDOGENOUS RECEPTORS | Université de Strasbourg (FR) | 2023-03-22 | — | — | EP | disclosed |
| CN-115516044-A | Fluorescent dimeric compounds useful as probes for the detection of endogenous receptors | 斯特拉斯堡大学 | 2022-12-23 | — | — | CN | disclosed |
| US-20080063627-A1 | Tissue graft materials containing biocompatible agent and methods of making and using same | SURMODICS, INC. | 2008-03-13 | — | — | US | disclosed |
| EP-1577670-A2 | Latent reactive polymers with biologically active moieties | SurModics, Inc. (US) | 2005-09-21 | — | — | EP | disclosed |
| EP-1003561-B1 | LATENT REACTIVE POLYMERS WITH BIOLOGICALLY ACTIVE MOIETIES | SURMODICS INC (US) | 2005-05-11 | — | — | EP | disclosed |
| US-20030181423-A1 | Reagent activated to form bulk material or brought into contact with surface of previously formed biomaterial and activated to form coating; pendent bioactive groups function by promoting attachment of specific molecules to surface | CLAPPER DAVID L (US) | 2003-09-25 | — | — | US | disclosed |
| US-6514734-B1 | Pendent bioactive groups function by promoting attachment of specific molecules or cells to the bulk material or coated surface; bioactive groups can include proteins, peptides, carbohydrates, and nucleic acids; e.g. neurons to electrodes | SURMODICS, INC. | 2003-02-04 | — | — | US | disclosed |
| US-6121027-A | FOR COATING BIOMATERIAL SURFACES AND FORMING A CROSSLINKED BIOMATERIAL | SURMODICS, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-1003561-A2 | LATENT REACTIVE POLYMERS WITH BIOLOGICALLY ACTIVE MOIETIES | SurModics, Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999008717-A2 | LATENT REACTIVE POLYMERS WITH BIOLOGICALLY ACTIVE MOIETIES | SURMODICS, INC. (US) | 1999-02-25 | — | — | WO | disclosed |
| US-5668291-A | THIOSUBSTITUTED PYRIDINES, TREATMENT OF AIDS AND HIV | WARNER-LAMBERT COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| US-4784961-A | NITROAMINO BENZOXADIAZOLE DERIVATIVE FLUORESCENT COMPOUNDS | ABBOTT LABORATORIES (US) | 1988-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080063627-A1 | Tissue graft materials containing biocompatible agent and methods of making and using same | COL1A1, COL14A1, PDGFA | DPP4 4041/4885GSR 918/4885CPB2 2178/4885 |
| US-20230174480-A1 | FLUOROGENIC DIMER COMPOUND, USEFUL AS A PROBE FOR DETECTION OF ENDOGENOUS RECEPTORS | GPR3, GPR174, GPR139 | DPP4 3617/4885GSR 2059/4885CPB2 1946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.