Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 2/20 | 0.41 |
| ▸ | HDAC11 known ✓ | Q96DB2 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 11/20 | 0.48 |
| ▸ | CES1 | P23141 | 10/20 | 0.48 |
| ▸ | CES2 | O00748 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457735 | 0.98 | FAAH (0.50) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL457766 | 0.98 | FAAH (0.50) | FAAHCES1CES2MEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL28412567 | 0.92 | FAAH (0.44) | FAAHCES1CES2MEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL28748106 | 0.92 | FAAH (0.44) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL17890011 | 0.88 | DNM1 (0.44) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28498503 | 0.86 | FAAH (0.40) | FAAHCES1CES2MEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL28836715 | 0.84 | FAAH (0.52) | FAAHCES1MEN1CYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL16538159 | 0.81 | FAAH (0.52) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL2410991 | 0.79 | FAAH (0.53) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL455073 | 0.79 | FAAH (0.53) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608517-A1 | SOLID COMPOSITION COMPRISING A CATIONIC SURFACTANT, A STARCH, AN AMPHOTERIC SURFACTANT AND A FATTY SUBSTANCE | L'OREAL (FR) | 2025-09-03 | — | — | EP | claimed |
| WO-2025051913-A1 | COSMETIC COMPOSITION COMPRISING A SOLID FATTY ALCOHOL, A CATIONIC SURFACTANT, AN AMPHOTERIC SURFACTANT, A PARTICULAR NONIONIC POLYSACCHARIDE AND A CATIONIC POLYMER | L'OREAL (FR) | 2025-03-13 | — | — | WO | claimed |
| WO-2024089165-A1 | SOLID COMPOSITION COMPRISING A CATIONIC SURFACTANT, A STARCH, AN AMPHOTERIC SURFACTANT AND A FATTY SUBSTANCE | L'OREAL (FR) | 2024-05-02 | — | — | WO | claimed |
| WO-2024089163-A1 | SOLID COMPOSITION COMPRISING A CATIONIC SURFACTANT, TWO STARCHES, A LIQUID FATTY SUBSTANCE AND A SPECIFIC AMOUNT OF WATER | L'OREAL (FR) | 2024-05-02 | — | — | WO | claimed |
| WO-2023070514-A1 | COMPOSITION FOR CLEANSING AND CONDITIONING THE HAIR | L'OREAL (FR) | 2023-05-04 | — | — | WO | claimed |
| US-20230047488-A1 | PROCESS FOR THE COSMETIC TREATMENT OF KERATIN FIBRES USING A DETERGENT COMPOSITION AND A RARE EARTH METAL COMPOSITION | L'OREAL (FR) | 2023-02-16 | — | — | US | claimed |
| EP-4076356-A1 | PROCESS FOR THE COSMETIC TREATMENT OF KERATIN FIBRES USING A DETERGENT COMPOSITION AND A RARE EARTH METAL COMPOSITION | L'OREAL (FR) | 2022-10-26 | — | — | EP | claimed |
| WO-2022117856-A1 | ANHYDROUS SOLID COMPOSITION COMPRISING A COMBINATION OF CARBOXYLATE AND SULFONATE ANIONIC SURFACTANTS, CATIONIC SURFACTANTS AND OPTIONALLY AMPHOTERIC OR ZWITTERIONIC SURFACTANTS | L'OREAL (FR) | 2022-06-09 | — | — | WO | claimed |
| WO-2021123003-A1 | PROCESS FOR THE COSMETIC TREATMENT OF KERATIN FIBRES USING A DETERGENT COMPOSITION AND A RARE EARTH METAL COMPOSITION | L'OREAL (FR) | 2021-06-24 | — | — | WO | claimed |
| CN-112888485-A | Cosmetic compositions, methods and uses thereof | 莱雅公司 | 2021-06-01 | — | — | CN | claimed |
| EP-3273934-B1 | COSMETIC HAIR TREATMENT METHOD | OREAL (FR) | 2019-04-24 | — | — | EP | claimed |
| US-20180064619-A1 | METHOD FOR COSMETIC TREATMENT OF THE HAIR | L'OREAL (FR) | 2018-03-08 | — | — | US | claimed |
| EP-4608517-A1 | SOLID COMPOSITION COMPRISING A CATIONIC SURFACTANT, A STARCH, AN AMPHOTERIC SURFACTANT AND A FATTY SUBSTANCE | L'OREAL (FR) | 2025-09-03 | — | — | EP | disclosed |
| US-20250127706-A1 | COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A POLYSACCHARIDE | L'OREAL (FR) | 2025-04-24 | — | — | US | disclosed |
| WO-2025051913-A1 | COSMETIC COMPOSITION COMPRISING A SOLID FATTY ALCOHOL, A CATIONIC SURFACTANT, AN AMPHOTERIC SURFACTANT, A PARTICULAR NONIONIC POLYSACCHARIDE AND A CATIONIC POLYMER | L'OREAL (FR) | 2025-03-13 | — | — | WO | disclosed |
| EP-4452215-A1 | COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A POLYSACCHARIDE | L'OREAL (FR) | 2024-10-30 | — | — | EP | disclosed |
| US-20180064619-A1 | METHOD FOR COSMETIC TREATMENT OF THE HAIR | L'OREAL (FR) | 2018-03-08 | — | — | US | disclosed |
| US-20170196780-A1 | FOAMING CLEANSER | L'OREAL (FR) | 2017-07-13 | — | — | US | disclosed |
| EP-3149137-A1 | FOAMING CLEANSER | L'OREAL (FR) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015181789-A1 | FOAMING CLEANSER | L'OREAL (FR) | 2015-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064619-A1 | METHOD FOR COSMETIC TREATMENT OF THE HAIR | SGMS2, SGMS1, CUTA | PPARG 340/4885HDAC11 91/4885FAAH 590/4885 |
| US-20170196780-A1 | FOAMING CLEANSER | CUTA, KRT18, ACR | PPARG 3816/4885HDAC11 2474/4885FAAH 22/4885 |
| US-20250127706-A1 | COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A POLYSACCHARIDE | H1-0, H1-10, HCAR3 | PPARG 87/4885HDAC11 265/4885FAAH 388/4885 |
| US-20230047488-A1 | PROCESS FOR THE COSMETIC TREATMENT OF KERATIN FIBRES USING A DETERGENT COMPOSITION AND A RARE EARTH METAL COMPOSITION | KRT18, DSG1, DSC1 | PPARG 284/4885HDAC11 76/4885FAAH 756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.