Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK known ✓ | Q08881 | 1/20 | 0.47 |
| ▸ | GLA known ✓ | P06280 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 10/20 | 0.47 |
| ▸ | CASP7 | P55210 | 10/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.47 |
| ▸ | USP2 | O75604 | 7/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29419155 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL12553801 | 0.99 | ALDH1A1 (0.51) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL15774206 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL376721 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL26968036 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL29419070 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL1963785 | 0.79 | ADORA2A (0.55) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL166859 | 0.79 | ALDH1A1 (0.64) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL29419105 | 0.79 | ALDH1A1 (0.64) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL1962817 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 757 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334175-B1 | PHENYL-SUBSTITUTED BICYCLOOCTANE 1,3 DIONE DERIVATIVES | BAYER IP GMBH (DE) | 2017-03-01 | — | — | EP | claimed |
| EP-2635550-B1 | PHENYL-SUBSTITUTED BICYCLOOCTANE-1,3-DIONE-DERIVATIVES | BAYER IP GMBH (DE) | 2016-01-27 | — | — | EP | claimed |
| US-9204640-B2 | 2-acyloxy-pyrrolin-4-ones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-08 | — | — | US | claimed |
| US-9198432-B2 | 1,2,4-triazolyl-substituted ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | claimed |
| EP-2681191-B1 | 2-ACYLOXY-PYRROLIN-4-ONES | BAYER IP GMBH (DE) | 2015-09-02 | — | — | EP | claimed |
| EP-2534147-B1 | SPIROHETEROCYCLIC-SUBSTITUTED TETRAMIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-06-17 | — | — | EP | claimed |
| US-8946124-B2 | Substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones for therapy and halogen-substituted spirocyclic ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-02-03 | — | — | US | claimed |
| EP-2210492-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-07-28 | — | — | EP | claimed |
| EP-2191719-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | claimed |
| EP-2191716-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | claimed |
| US-20260144250-A1 | SOLVENT-FREE FORMULATIONS OF LOW-MELTING ACTIVE INGREDIENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2026-05-28 | — | — | US | disclosed |
| US-20260138958-A1 | SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AG (DE) | 2026-05-21 | — | — | US | disclosed |
| US-12599136-B2 | Substituted isophthalic acid diamides and their use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2026-04-14 | — | — | US | disclosed |
| US-12509445-B2 | Herbicidally active 4-cyclopropyl-6-[4-(trifluormethyl)pyrazol-1-yl)]pyrimidines | BAYER AKTIENGESELLSCHAFT (DE) | 2025-12-30 | — | — | US | disclosed |
| US-12492173-B2 | Herbicidal substituted N-tetrazolyl aryl carboxamides | BAYER AKTIENGESELLSCHAFT (DE) | 2025-12-09 | — | — | US | disclosed |
| EP-2052616-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2009-04-29 | — | — | EP | disclosed |
| EP-2052614-A1 | Herbicide combination | Bayer CropScience AG (DE) | 2009-04-29 | — | — | EP | disclosed |
| EP-1746880-A1 | QUINOXALIN-2-ONE DERIVATIVES CROP PROTECTION AGENTS COMPRISING THE SAME AND METHOD FOR PRODUCTION AND USE THEROF | Bayer CropScience GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005112630-A1 | QUINOXALIN-2-ONE DERIVATIVES CROP PROTECTION AGENTS COMPRISING THE SAME AND METHOD FOR PRODUCTION AND USE THEROF | BAYER CROPSCIENCE GMBH (DE) | 2005-12-01 | — | — | WO | disclosed |
| US-20050256000-A1 | Quinoxalin-2-one derivatives, compositions which protect useful plants and comprise these derivatives, and processes for their preparation and their use | BAYER CROPSCIENCE GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260138958-A1 | SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | CBR1, CBR3, HDHD5 | ITK 2938/4885GLA 2535/4885ALDH1A1 148/4885 |
| US-20260144250-A1 | SOLVENT-FREE FORMULATIONS OF LOW-MELTING ACTIVE INGREDIENTS | FOXM1, CSDE1, RCC1 | ITK 3447/4885GLA 1490/4885ALDH1A1 692/4885 |
| US-20050256000-A1 | Quinoxalin-2-one derivatives, compositions which protect useful plants and comprise these derivatives, and processes for their preparation and their use | QSOX1, CYC1, CBR3 | ITK 3213/4885GLA 1764/4885ALDH1A1 1058/4885 |
| US-12492173-B2 | Herbicidal substituted N-tetrazolyl aryl carboxamides | DDT, CYP4X1, AADAC | ITK 2271/4885GLA 1064/4885ALDH1A1 424/4885 |
| US-12509445-B2 | Herbicidally active 4-cyclopropyl-6-[4-(trifluormethyl)pyrazol-1-yl)]pyrimidines | CBR3, CBR1, HAX1 | ITK 4062/4885GLA 3771/4885ALDH1A1 705/4885 |
| US-12599136-B2 | Substituted isophthalic acid diamides and their use as herbicides | P4HA1, DDT, CNPY2 | ITK 3887/4885GLA 3751/4885ALDH1A1 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.