Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 known ✓ | Q12809 | 3/20 | 0.56 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.46 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.46 |
| ▸ | S1PR1 known ✓ | P21453 | 1/20 | 0.46 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.46 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.46 |
| ▸ | S1PR5 known ✓ | Q9H228 | 1/20 | 0.46 |
| ▸ | KLKB1 known ✓ | P03952 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30002058 | 0.91 | FFAR1 (0.50) | KCNH2FFAR1CARM1PRMT6MAOA | |
| Hydrochloric Acid SCHEMBL30001586 | 0.83 | MAOB (0.60) | FFAR1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL29386628 | 0.83 | KCNH2 (0.79) | KCNH2CARM1PRMT6S1PR1S1PR5 | |
| SCHEMBL27212695 | 0.82 | KCNH2 (0.78) | KCNH2CARM1PRMT6S1PR1S1PR5 | |
| SCHEMBL30001621 | 0.79 | MAOB (0.52) | KCNH2FFAR1MAOAMAOBS1PR1 | |
| SCHEMBL30002041 | 0.79 | MAOB (0.52) | KCNH2FFAR1MAOAMAOBS1PR1 | |
| Hydrochloric Acid SCHEMBL29385897 | 0.76 | KCNH2 (0.69) | KCNH2CARM1PRMT6S1PR1S1PR5 | |
| SCHEMBL21377326 | 0.76 | MRGPRX4 (0.52) | FFAR1MAOB | |
| SCHEMBL27212676 | 0.75 | KCNH2 (0.68) | KCNH2CARM1PRMT6S1PR1S1PR5 | |
| SCHEMBL17894442 | 0.74 | MAOB (0.48) | KCNH2MAOAMAOBS1PR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250205195-A1 | BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION | AMTIXBIO CO., LTD. (KR) | 2025-06-26 | — | — | US | claimed |
| US-20250034083-A1 | METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES | AMTIXBIO CO., LTD. (KR) | 2025-01-30 | — | — | US | claimed |
| US-20250034084-A1 | COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS | AMTIXBIO CO., LTD. (KR) | 2025-01-30 | — | — | US | claimed |
| US-20250034085-A1 | COMPOSITION AND METHODS FOR PREVENTING OR TREATING PHYTOPATHOGENIC FUNGAL INFECTION | AMTIXBIO CO., LTD. (KR) | 2025-01-30 | — | — | US | claimed |
| EP-4349329-A1 | BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION | Amtixbio Co., Ltd. (KR) | 2024-04-10 | — | — | EP | claimed |
| WO-2022255801-A1 | BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION | (주)앰틱스바이오 | 2022-12-08 | — | — | WO | claimed |
| US-20250205195-A1 | BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION | AMTIXBIO CO., LTD. (KR) | 2025-06-26 | — | — | US | disclosed |
| US-20250034085-A1 | COMPOSITION AND METHODS FOR PREVENTING OR TREATING PHYTOPATHOGENIC FUNGAL INFECTION | AMTIXBIO CO., LTD. (KR) | 2025-01-30 | — | — | US | disclosed |
| US-20250034083-A1 | METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES | AMTIXBIO CO., LTD. (KR) | 2025-01-30 | — | — | US | disclosed |
| US-20250034084-A1 | COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS | AMTIXBIO CO., LTD. (KR) | 2025-01-30 | — | — | US | disclosed |
| US-20250034082-A1 | FUNCTIONAL DERIVATIVE COMPOUNDS OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | AMTIXBIO CO., LTD. (KR) | 2025-01-30 | — | — | US | disclosed |
| EP-4349329-A1 | BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION | Amtixbio Co., Ltd. (KR) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022255801-A1 | BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION | (주)앰틱스바이오 | 2022-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034083-A1 | METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES | BCAT2, BCAT1, DAO | KCNH2 2388/4885MAOA 539/4885MAOB 134/4885 |
| US-20250034082-A1 | FUNCTIONAL DERIVATIVE COMPOUNDS OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | PEPD, BCAT1, ANPEP | KCNH2 4302/4885MAOA 2029/4885MAOB 2432/4885 |
| US-20250034084-A1 | COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS | ERG28, BCAT2, AADAT | KCNH2 3321/4885MAOA 1412/4885MAOB 1969/4885 |
| US-20250034085-A1 | COMPOSITION AND METHODS FOR PREVENTING OR TREATING PHYTOPATHOGENIC FUNGAL INFECTION | PEPD, PREP, ANPEP | KCNH2 3383/4885MAOA 2181/4885MAOB 2680/4885 |
| US-20250205195-A1 | BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION | TSLP, IL2RA, TRPC7 | KCNH2 3897/4885MAOA 4463/4885MAOB 3904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.