Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109790 | 0.99 | ALDH1A1 (0.62) | ALDH1A1TSHRTDP1HCAR3MAPT | |
| SCHEMBL8748875 | 0.92 | ALDH1A1 (0.71) | ALDH1A1TSHRTDP1HCAR3MAPT | |
| SCHEMBL17693663 | 0.90 | ALDH1A1 (0.65) | ALDH1A1TSHRTDP1HCAR3MAPT | |
| Hydrochloric Acid SCHEMBL1136861 | 0.87 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1HCAR3MAPT | |
| SCHEMBL111249 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1HCAR3MAPT | |
| Hydrochloric Acid SCHEMBL454521 | 0.85 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1HCAR3MAPT | |
| Hydrochloric Acid SCHEMBL30100543 | 0.85 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1HCAR3MAPT | |
| SCHEMBL7590622 | 0.85 | ALDH1A1 (0.70) | ALDH1A1TSHRTDP1HCAR3MAPT | |
| Hydrochloric Acid SCHEMBL10799230 | 0.84 | ALDH1A1 (0.70) | ALDH1A1TSHRTDP1HCAR3MAPT | |
| SCHEMBL210589 | 0.84 | ALDH1A1 (0.85) | ALDH1A1TSHRTDP1HCAR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11298304-B2 | Two component hair treatment kit comprising a hair coloring cream and a developer composition comprising a specific tensioactive compound | LABORATOIRE BIOSTHÉTIQUE KOSMETIK GMBH & CO. KG (DE) | 2022-04-12 | — | — | US | disclosed |
| US-20210128427-A1 | TWO COMPONENT HAIR TREATMENT KIT COMPRISING A HAIR COLORING CREAM AND A DEVELOPER COMPOSITION COMPRISING A SPECIFIC TENSIOACTIVE COMPOUND | LABORATOIRE BIOSTHÉTIQUE KOSMETIK GMBH & CO. KG (DE) | 2021-05-06 | — | — | US | disclosed |
| EP-3773435-A1 | TWO COMPONENT HAIR TREATMENT KIT COMPRISING A HAIR COLORING CREAM AND A DEVELOPER COMPOSITION COMPRISING A SPECIFIC TENSIOACTIVE COMPOUND | Laboratoire Biosthetique Kosmetik GmbH&Co. KG (DE) | 2021-02-17 | — | — | EP | disclosed |
| CN-111936110-A | Two-component hair treatment kit comprising a hair dye cream and a developer composition comprising specific surface-active compounds | 科斯梅蒂克生物技术实验室有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-106794127-B | Permanent hair dye based on an emulsion-like vehicle and a combination of tris (hydroxymethyl) aminomethane, at least one amino acid and an oxidation dye | HCT-头发化妆品技术股份公司 | 2020-05-29 | — | — | CN | disclosed |
| US-10456341-B2 | Compositions and methods for simultaneous reshaping and direct coloring of hair | ALFA PARF GROUP S.P.A. (IT) | 2019-10-29 | — | — | US | disclosed |
| WO-2019185127-A1 | TWO COMPONENT HAIR TREATMENT KIT COMPRISING A HAIR COLORING CREAM AND A DEVELOPER COMPOSITION COMPRISING A SPECIFIC TENSIOACTIVE COMPOUND | HCT - HAIR COSMETIC TECHNOLOGY AG (CH) | 2019-10-03 | — | — | WO | disclosed |
| EP-2979683-B1 | Permanent hair colorants based on a cream-like carrier and a combination of tris(hydroxymethyl)aminomethane, at least an amino acid and an oxidative dye | HCT HAIR COSMETIC TECH AG (CH) | 2019-07-24 | — | — | EP | disclosed |
| US-10259946-B1 | Sealing agents, methods of making and uses thereof | James Hardie Technology Limited (IE) | 2019-04-16 | — | — | US | disclosed |
| US-10039701-B2 | Permanent hair colorants based on a cream-like carrier and a combination of tris(hydroxymethyl) aminomethane, at least an amino acid and an oxidative dye | HCT—Hair Cosmetic Technology AG (CH) | 2018-08-07 | — | — | US | disclosed |
| US-6106579-A | MIXTURE OF OXOCARBOXYLIC ACID AND REDUCING AGENT | WELLA AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | disclosed |
| EP-1002516-A1 | Hair dyes containing indan derivatives | Wella Aktiengesellschaft (DE) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999059529-A2 | AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |
| EP-0943316-A2 | Means for coloring and decoloring of hair | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |
| EP-0898954-A2 | Composition for dyeing keratin fibres | Wella Aktiengesellschaft (DE) | 1999-03-03 | — | — | EP | disclosed |
| EP-0891971-A1 | Bispyrazole-aza compounds, processes for their preparation, and hair dyeing agents containing these compounds | Wella Aktiengesellschaft (DE) | 1999-01-20 | — | — | EP | disclosed |
| EP-0889719-A1 | AGENTS FOR DYING AND DECOLORIZING FIBERS | Wella Aktiengesellschaft (DE) | 1999-01-13 | — | — | EP | disclosed |
| EP-0877593-A1 | AGENT FOR DYEING AND DECOLORIZING FIBERS | Wella Aktiengesellschaft (DE) | 1998-11-18 | — | — | EP | disclosed |
| WO-1998023247-A1 | AGENT FOR DYEING AND DECOLORIZING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1998-06-04 | — | — | WO | disclosed |
| WO-1998022078-A1 | AGENTS FOR DYING AND DECOLORIZING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128427-A1 | TWO COMPONENT HAIR TREATMENT KIT COMPRISING A HAIR COLORING CREAM AND A DEVELOPER COMPOSITION COMPRISING A SPECIFIC TENSIOACTIVE COMPOUND | KRT18, KIT, PRKDC | GLA 1785/4885ALDH1A1 163/4885TSHR 3801/4885 |
| US-11298304-B2 | Two component hair treatment kit comprising a hair coloring cream and a developer composition comprising a specific tensioactive compound | KRT18, KIT, PRKDC | GLA 1785/4885ALDH1A1 163/4885TSHR 3801/4885 |
| US-10039701-B2 | Permanent hair colorants based on a cream-like carrier and a combination of tris(hydroxymethyl) aminomethane, at least an amino acid and an oxidative dye | KRT18, CUTA, ALKBH2 | GLA 2612/4885ALDH1A1 145/4885TSHR 3548/4885 |
| US-10456341-B2 | Compositions and methods for simultaneous reshaping and direct coloring of hair | GRHPR, DAO, ALPG | GLA 107/4885ALDH1A1 438/4885TSHR 3973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.