Hydrochloric Acid

Hydrochloric Acid

SCHEMBL693195

Cl.Cl.NCC(N)c1cccc2ccccc12

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1B known ✓ P28222 2/20 0.43
ADRA2A known ✓ P08913 2/20 0.41
ADRA2B known ✓ P18089 2/20 0.41
ADRA2C known ✓ P18825 2/20 0.41
SLC6A4 known ✓ P31645 1/20 0.40
ADRA1D known ✓ P25100 1/20 0.39
ADRA1A known ✓ P35348 1/20 0.39
ADRA1B known ✓ P35368 1/20 0.39
ALDH1A1 P00352 4/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
NR2E1 Q9Y466 1/20 0.45
AOC3 Q16853 1/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
RECQL P46063 1/20 0.42
CYP3A4 P08684 1/20 0.40
HPGD P15428 1/20 0.40
KEAP1 Q14145 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2475384 1.00 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2C9CYP2C19NR2E1
Hydrochloric Acid SCHEMBL2455223 1.00 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2C9CYP2C19NR2E1
SCHEMBL9751547 0.98 ALDH1A1 (0.52) ALDH1A1CYP1A2CYP2C9CYP2C19NR2E1
SCHEMBL342584 0.98 ALDH1A1 (0.52) ALDH1A1CYP1A2CYP2C9CYP2C19NR2E1
SCHEMBL30509738 0.98 ALDH1A1 (0.52) ALDH1A1CYP1A2CYP2C9CYP2C19NR2E1
Water SCHEMBL28672744 0.96 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2C9CYP2C19NR2E1
Water SCHEMBL28312483 0.96 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2C9CYP2C19NR2E1
Nitrous Acid SCHEMBL27835231 0.90 NR2E1 (0.42) ALDH1A1CYP1A2CYP2C9CYP2C19NR2E1
Oxalic Acid SCHEMBL17065865 0.88 ALDH1A1 (0.48) ALDH1A1CYP1A2CYP2C9CYP2C19NR2E1
Phosphoric Acid SCHEMBL27872527 0.88 ACP3 (0.51) ALDH1A1CYP1A2CYP2C9CYP2C19NR2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116625964-A Continuous detection method and system for total nitrogen in water 山东达峰海洋科技有限公司 2023-08-22 CN claimed
CN-113218895-B Detection system and method for determining total nitrogen content in water 苏州微湃医疗科技有限公司 2023-04-07 CN claimed
CN-115003509-A Improved ink formulations for printing and preparing reactive chemical sensors 韦里特克美国有限公司 2022-09-02 CN claimed
CN-109827916-B Water quality nitrate detection method based on zinc-cadmium reduction salt-free effect 国家海洋局东海环境监测中心(国家海洋局东海海洋工程勘察设计研究所) 2021-11-16 CN claimed
CN-113218895-A Detection system and method for determining total nitrogen content in water 苏州微湃医疗科技有限公司 2021-08-06 CN claimed
WO-2021081199-A1 IMPROVED INK FORMULATIONS FOR PRINTING AND MANUFACTURE OF REACTIVE CHEMICAL SENSORS VERITEQUE USA, INC. (US) 2021-04-29 WO claimed
CN-108717043-A A kind of nitrite detection plate 安徽省环境监测中心站 2018-10-30 CN claimed
CN-202903683-U Kit for rapidly detecting nitrite nitrogen in water sample HAFLRU 2013-04-24 CN claimed
US-6699533-B2 A CHROMONIC QUATERNARY AMMONIUM COMPOUND WITH HETEROCYCLIC RING COVALENTLY ATTACHED TO A TRIAZINE RING WITH TWO BENZENE RINGS WHICH POSSESES ATLEAST TWO CARBOXY OR SULFONIC OR PHOSPHONIC GROUPS, A PRE-TILT ADDITIVE, A CROSS-LINKING AGENT 3M INNOVATIVE PROPERTIES COMPANY 2004-03-02 US claimed
US-20020066885-A1 Stabilized liquid crystal alignment structure with pre-tilt angle and display devices containing the same 3M INNOVATIVE PROPERTIES COMPANY 2002-06-06 US claimed
JP-4073257-A None JP disclosed
US-20260146130-A1 POLYMER DOT, PREPARATION METHOD AND USE THEREOF CHINA MEDICAL UNIVERSITY (TW) 2026-05-28 US disclosed
US-20260137725-A1 ANIMAL-DERIVED POLYMER DOT, PREPARATION METHOD AND USE THEREOF CHINA MEDICAL UNIVERSITY (TW) 2026-05-21 US disclosed
US-12534439-B2 Xanthohumol derivatives and methods for making and using OREGON STATE UNIVERSITY (US) 2026-01-27 US disclosed
US-20250319002-A1 BISACURONE COMPOSITION AND METHOD OF SKIN WHITENING Vidya Herbs, Inc. (US) 2025-10-16 US disclosed
US-4629696-A USING NADPH, A DIAPHORASE AND A REDOX PARTNER TO PRODUCE SUPEROXIDE, HYDROGEN PEROXIDE OR HYDROXYL RADICALS; QUANTITATIVE ANALYSIS BOEHRINGER MANNHEIM GMBH (DE) 1986-12-16 US disclosed
EP-0105443-B1 METHOD OF SELECTIVELY PRODUCING REDUCED OXYGEN SPECIES AND REAGENTS SUITABLE THEREFOR Roche Diagnostics GmbH (DE) 1986-07-02 EP disclosed
EP-0105443-A2 Method of selectively producing reduced oxygen species and reagents suitable therefor Roche Diagnostics GmbH (DE) 1984-04-18 EP disclosed
EP-0000089-A1 Imidazole-2-carbamates and process for their production and pharmaceutical compositions containing them. SYNTEX (U.S.A.) INC. (US) 1978-12-20 EP disclosed
US-4110463-A IMIDAZOLE-2-CARBAMATES SYNTEX (U.S.A.) INC. (US) 1978-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534439-B2 Xanthohumol derivatives and methods for making and using MT-CO1, MT-CO2, PC HTR1B 1442/4885ADRA2A 1993/4885ADRA2B 1644/4885
US-20260137725-A1 ANIMAL-DERIVED POLYMER DOT, PREPARATION METHOD AND USE THEREOF MPO, LPO, CAT HTR1B 4873/4885ADRA2A 2855/4885ADRA2B 3366/4885
US-20260146130-A1 POLYMER DOT, PREPARATION METHOD AND USE THEREOF CAT, MPO, LPO HTR1B 4622/4885ADRA2A 2914/4885ADRA2B 2646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.