Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 known ✓ | P09884 | 1/20 | 0.41 |
| ▸ | PPARG known ✓ | P37231 | 2/20 | 0.41 |
| ▸ | HDAC11 known ✓ | Q96DB2 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8331673 | 1.00 | DNM1 (0.49) | DNM1DGKALMNAPAMMAPT | |
| Hydrochloric Acid SCHEMBL28400971 | 1.00 | DNM1 (0.49) | DNM1DGKALMNAPAMMAPT | |
| SCHEMBL6220963 | 0.98 | DNM1 (0.50) | DNM1DGKALMNAPAMMAPT | |
| Sulfuric Acid SCHEMBL29112174 | 0.92 | DNM1 (0.45) | DNM1DGKALMNAPAMMAPT | |
| Hydrochloric Acid SCHEMBL16611477 | 0.91 | FAAH (0.50) | DGKALMNAMAPTCES1KMT2A | |
| Hydrochloric Acid SCHEMBL16611476 | 0.91 | FAAH (0.50) | DGKALMNAMAPTCES1KMT2A | |
| SCHEMBL6857401 | 0.84 | DNM1 (0.39) | DNM1DGKALMNAPAMMAPT | |
| Hydrochloric Acid SCHEMBL7213485 | 0.82 | DNM1 (0.46) | DNM1DGKALMNAPAMMAPT | |
| Hydrochloric Acid SCHEMBL7213491 | 0.82 | MAPT (0.47) | DNM1DGKALMNAPAMMAPT | |
| Hydrochloric Acid SCHEMBL29417625 | 0.81 | DGKA (0.55) | DGKALMNAPAMMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113081887-A | Scalp care shampoo composition with high sea salt content and preparation method thereof | 佩莱品牌管理有限公司 | 2021-07-09 | — | — | CN | claimed |
| CN-112190493-A | Anhydrous transparent liquid head conditioning composition and preparation method thereof | 广州荃智美肤生物科技研究院有限公司 | 2021-01-08 | — | — | CN | claimed |
| CN-112076108-A | Children hair cleaning product containing bionic phospholipid structure conditioning agent | 福建省梦娇兰日用化学品有限公司 | 2020-12-15 | — | — | CN | claimed |
| CN-113081887-A | Scalp care shampoo composition with high sea salt content and preparation method thereof | 佩莱品牌管理有限公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-112076108-A | Children hair cleaning product containing bionic phospholipid structure conditioning agent | 福建省梦娇兰日用化学品有限公司 | 2020-12-15 | — | — | CN | disclosed |
| EP-3279300-B1 | FRAGRANCE COMPOSITION | KAO CORP (JP) | 2019-03-27 | — | — | EP | disclosed |
| EP-3279300-A1 | FRAGRANCE COMPOSITION | KAO CORPORATION (JP) | 2018-02-07 | — | — | EP | disclosed |
| EP-2857482-B1 | PERFUME COMPOSITION | KAO CORP (JP) | 2017-10-11 | — | — | EP | disclosed |
| US-9567550-B2 | Fragrance composition | KAO CORPORATION (JP) | 2017-02-14 | — | — | US | disclosed |
| US-20160376521-A1 | PERFUME COMPOSITION | KAO CORPORATION (JP) | 2016-12-29 | — | — | US | disclosed |
| US-20160326457-A1 | ESTER | KAO CORPORATION (JP) | 2016-11-10 | — | — | US | disclosed |
| EP-3075822-A1 | PERFUME COMPOSITION | Kao Corporation (JP) | 2016-10-05 | — | — | EP | disclosed |
| US-20150118174-A1 | FRAGRANCE COMPOSITION | KAO CORPORATION (JP) | 2015-04-30 | — | — | US | disclosed |
| EP-2857482-A1 | PERFUME COMPOSITION | Kao Corporation (JP) | 2015-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150118174-A1 | FRAGRANCE COMPOSITION | FAAH2, FAAH, DACH1 | POLA1 3808/4885PPARG 2598/4885HDAC11 760/4885 |
| US-20160376521-A1 | PERFUME COMPOSITION | DEGS1, ALG3, DHCR24 | POLA1 2821/4885PPARG 320/4885HDAC11 3134/4885 |
| US-20160326457-A1 | ESTER | MEP1A, ELOVL1, EBP | POLA1 1922/4885PPARG 1695/4885HDAC11 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.