Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA known ✓ | P17252 | 1/20 | 0.47 |
| ▸ | PRKCE known ✓ | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ known ✓ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCD known ✓ | Q05655 | 1/20 | 0.47 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28400968 | 1.00 | LMNA (0.58) | LMNAMAPTMAPK1DNM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8331677 | 1.00 | LMNA (0.58) | LMNAMAPTMAPK1DNM1ALDH1A1 | |
| SCHEMBL6220960 | 0.98 | LMNA (0.59) | LMNAMAPTMAPK1DNM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16611478 | 0.91 | PRKCA (0.54) | LMNAMAPTALDH1A1PRKCAPRKCE | |
| SCHEMBL11862785 | 0.84 | MAPK1 (0.66) | LMNAMAPTMAPK1DNM1ALDH1A1 | |
| SCHEMBL26613661 | 0.84 | LMNA (0.59) | LMNAMAPTMAPK1DNM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7213487 | 0.83 | MAPT (0.51) | LMNAMAPTMAPK1DNM1ALDH1A1 | |
| SCHEMBL15228719 | 0.83 | LMNA (0.62) | LMNAMAPTMAPK1DNM1ALDH1A1 | |
| SCHEMBL8396305 | 0.83 | LMNA (0.62) | LMNAMAPTMAPK1DNM1ALDH1A1 | |
| SCHEMBL8394932 | 0.83 | LMNA (0.62) | LMNAMAPTMAPK1DNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113081887-A | Scalp care shampoo composition with high sea salt content and preparation method thereof | 佩莱品牌管理有限公司 | 2021-07-09 | — | — | CN | claimed |
| CN-112190493-A | Anhydrous transparent liquid head conditioning composition and preparation method thereof | 广州荃智美肤生物科技研究院有限公司 | 2021-01-08 | — | — | CN | claimed |
| CN-112076108-A | Children hair cleaning product containing bionic phospholipid structure conditioning agent | 福建省梦娇兰日用化学品有限公司 | 2020-12-15 | — | — | CN | claimed |
| CN-121177161-A | Composition containing enzymatic prinsepia utilis royle oil microcapsule, preparation method and application | 澳宝化妆品（惠州）有限公司 | 2025-12-23 | — | — | CN | disclosed |
| CN-115427007-A | Transparent shampoo block and preparation method thereof | 汉高股份有限及两合公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-113081887-A | Scalp care shampoo composition with high sea salt content and preparation method thereof | 佩莱品牌管理有限公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-112076108-A | Children hair cleaning product containing bionic phospholipid structure conditioning agent | 福建省梦娇兰日用化学品有限公司 | 2020-12-15 | — | — | CN | disclosed |
| EP-3279300-B1 | FRAGRANCE COMPOSITION | KAO CORP (JP) | 2019-03-27 | — | — | EP | disclosed |
| EP-3279300-A1 | FRAGRANCE COMPOSITION | KAO CORPORATION (JP) | 2018-02-07 | — | — | EP | disclosed |
| EP-2857482-B1 | PERFUME COMPOSITION | KAO CORP (JP) | 2017-10-11 | — | — | EP | disclosed |
| US-9567550-B2 | Fragrance composition | KAO CORPORATION (JP) | 2017-02-14 | — | — | US | disclosed |
| US-20160376521-A1 | PERFUME COMPOSITION | KAO CORPORATION (JP) | 2016-12-29 | — | — | US | disclosed |
| US-20160326457-A1 | ESTER | KAO CORPORATION (JP) | 2016-11-10 | — | — | US | disclosed |
| EP-3075822-A1 | PERFUME COMPOSITION | Kao Corporation (JP) | 2016-10-05 | — | — | EP | disclosed |
| US-20150118174-A1 | FRAGRANCE COMPOSITION | KAO CORPORATION (JP) | 2015-04-30 | — | — | US | disclosed |
| EP-2857482-A1 | PERFUME COMPOSITION | Kao Corporation (JP) | 2015-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150118174-A1 | FRAGRANCE COMPOSITION | FAAH2, FAAH, DACH1 | PRKCA 4084/4885PRKCE 3414/4885PRKCQ 4178/4885 |
| US-20160376521-A1 | PERFUME COMPOSITION | DEGS1, ALG3, DHCR24 | PRKCA 2622/4885PRKCE 1488/4885PRKCQ 2195/4885 |
| US-20160326457-A1 | ESTER | MEP1A, ELOVL1, EBP | PRKCA 1635/4885PRKCE 487/4885PRKCQ 2047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.