Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3487783 | 0.81 | KIF11 (0.41) | TSHRKIF11MEN1KMT2AKDM4E | |
| SCHEMBL27669800 | 0.73 | CRHBP (0.46) | TSHRNR1H2NR1H3MEN1KMT2A | |
| SCHEMBL3190702 | 0.72 | KCNN4 (0.39) | TSHRCNR2NR1H2NR1H3MEN1 | |
| SCHEMBL22928368 | 0.71 | KIF11 (0.46) | KIF11NPC1RAB9ALMNA | |
| SCHEMBL9564928 | 0.70 | ALDH1A1 (0.41) | TSHRCNR2KIF11MEN1KMT2A | |
| SCHEMBL9821084 | 0.69 | ALDH1A1 (0.44) | TSHRHSD11B1MEN1KMT2AKDM4E | |
| SCHEMBL10588072 | 0.68 | MEN1 (0.33) | TSHRCNR2NR1H2NR1H3MEN1 | |
| SCHEMBL6299189 | 0.66 | TSHR (0.46) | TSHRCNR2MEN1KMT2ANPC1 | |
| SCHEMBL31718395 | 0.66 | TSHR (0.46) | TSHRCNR2MEN1KMT2ANPC1 | |
| SCHEMBL8958015 | 0.66 | MEN1 (0.39) | TSHRHSD11B1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11110121-B2 | Compositions comprising hydrogen peroxide or hydrogen peroxide donor substances | CLARIANT INTERNATIONAL LTD. (CH) | 2021-09-07 | — | — | US | disclosed |
| US-10406135-B2 | Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group | CLARIANT INTERNATIONAL LTD. (CH) | 2019-09-10 | — | — | US | disclosed |
| US-9295626-B2 | Compositions comprising isosorbide monoester and N-hydroxypyridones | CLARIANT INTERNATIONAL LTD. (CH) | 2016-03-29 | — | — | US | disclosed |
| US-20160000080-A1 | COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALIPHATIC VICINAL DIOLS | CLARIANT INTERNATIONAL LTD. (CH) | 2016-01-07 | — | — | US | disclosed |
| US-8962796-B2 | Modified variant Bowman Birk protease inhibitors | DANISCO US INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140369943-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND HALOGENATED ANTIMICROBIAL ACTIVE COMPOUNDS | CLARIANT INTERNATIONAL LTD. (CH) | 2014-12-18 | — | — | US | disclosed |
| US-20140348763-A1 | COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALCOHOLS THAT CONTAIN AT LEAST ONE AROMATIC GROUP | CLARIANT INTERNATIONAL LTD. (CH) | 2014-11-27 | — | — | US | disclosed |
| US-20140343171-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTER AND N-HYDROXYPYRIDONES | CLARIANT INTERNATIONAL LTD. (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140329870-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND ISOTHIAZOLINONES | CLARIANT INTERNATIONAL LTD. (CH) | 2014-11-06 | — | — | US | disclosed |
| US-20140308224-A1 | COSMETIC, DERMATOLOGICAL OR PHARMACEUTICAL COMPOSITIONS COMPRISING ISOSORBIDE DIESTERS AND UV FILTERS | CLARIANT INTERNATIONAL LTD. (CH) | 2014-10-16 | — | — | US | disclosed |
| US-20070031361-A1 | Cosmetic, pharmaceutical and dermatological preparations comprising homopolymer and/or copolymer waxes of the monomers ethylene and/or propylene | HERRMANN HANS-FRIEDRICH | 2007-02-08 | — | — | US | disclosed |
| US-20060246149-A1 | Antimicrobial pigments | MERCK PATENT GMBH (DE) | 2006-11-02 | — | — | US | disclosed |
| US-20060210500-A1 | Formulations | MERCK PATENT GMBH (DE) | 2006-09-21 | — | — | US | disclosed |
| US-20060104940-A1 | Cosmetic, pharmaceutical and dermatological preparations comprising copolymer waxes | CLARIANT GMBH | 2006-05-18 | — | — | US | disclosed |
| EP-1633818-A2 | ANTIMICROBIAL PIGMENTS | MERCK PATENT GmbH (DE) | 2006-03-15 | — | — | EP | disclosed |
| US-20050276763-A1 | Emulsion concentrate containing water-soluble and oil-soluble polymers | BEIERSDORF AG | 2005-12-15 | — | — | US | disclosed |
| US-20050238679-A1 | Taurine-containing preparations for improving the skin barrier | BEIERSDORF AG (DE) | 2005-10-27 | — | — | US | disclosed |
| US-20050201969-A1 | Stable cosmetics | BEIERSDORF AG | 2005-09-15 | — | — | US | disclosed |
| US-20050074471-A1 | Self-foaming or foamy preparations comprising particulate hydrophobic and/or hydrophobized and/or oil-absorbent solid substances | BEIERSDORF AG (DE) | 2005-04-07 | — | — | US | disclosed |
| WO-2004092283-A2 | ANTIMICROBIAL PIGMENTS | MERCK PATENT GMBH (DE) | 2004-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070031361-A1 | Cosmetic, pharmaceutical and dermatological preparations comprising homopolymer and/or copolymer waxes of the monomers ethylene and/or propylene | PMS2, MSH2, PGM2 | TSHR 2791/4885CNR2 1861/4885NR1H2 2923/4885 |
| US-20050074471-A1 | Self-foaming or foamy preparations comprising particulate hydrophobic and/or hydrophobized and/or oil-absorbent solid substances | HBB, HBG1, FFAR1 | TSHR 2846/4885CNR2 189/4885NR1H2 107/4885 |
| US-20060104940-A1 | Cosmetic, pharmaceutical and dermatological preparations comprising copolymer waxes | CUTA, ACMSD, DEGS1 | TSHR 3118/4885CNR2 451/4885NR1H2 297/4885 |
| US-20140308224-A1 | COSMETIC, DERMATOLOGICAL OR PHARMACEUTICAL COMPOSITIONS COMPRISING ISOSORBIDE DIESTERS AND UV FILTERS | POLR1C, CUTA, DEGS1 | TSHR 2901/4885CNR2 604/4885NR1H2 96/4885 |
| US-20050276763-A1 | Emulsion concentrate containing water-soluble and oil-soluble polymers | PCNA, CUTA, PCLAF | TSHR 4134/4885CNR2 937/4885NR1H2 486/4885 |
| US-11110121-B2 | Compositions comprising hydrogen peroxide or hydrogen peroxide donor substances | GPX4, LPO, CAT | TSHR 2479/4885CNR2 4301/4885NR1H2 1882/4885 |
| US-20050238679-A1 | Taurine-containing preparations for improving the skin barrier | CETP, CUTA, SPTLC3 | TSHR 4020/4885CNR2 2617/4885NR1H2 72/4885 |
| US-20140348763-A1 | COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALCOHOLS THAT CONTAIN AT LEAST ONE AROMATIC GROUP | ADH5, ADH1A, ADH1C | TSHR 3415/4885CNR2 2976/4885NR1H2 67/4885 |
| US-20160000080-A1 | COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALIPHATIC VICINAL DIOLS | HSD17B12, DHCR7, ERG28 | TSHR 4673/4885CNR2 1067/4885NR1H2 44/4885 |
| US-20060246149-A1 | Antimicrobial pigments | LPO, TYR, CUTA | TSHR 1779/4885CNR2 4833/4885NR1H2 4416/4885 |
| US-10406135-B2 | Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group | ADH5, ADH1A, ADH1C | TSHR 3415/4885CNR2 2976/4885NR1H2 67/4885 |
| US-20140343171-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTER AND N-HYDROXYPYRIDONES | HSD17B3, HSD3B1, HSD3B2 | TSHR 3430/4885CNR2 1129/4885NR1H2 99/4885 |
| US-20140369943-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND HALOGENATED ANTIMICROBIAL ACTIVE COMPOUNDS | FASN, HSD17B12, ELOVL3 | TSHR 2333/4885CNR2 3872/4885NR1H2 39/4885 |
| US-20060210500-A1 | Formulations | TYR, SUCLG1, CYB5R3 | TSHR 3474/4885CNR2 4350/4885NR1H2 3428/4885 |
| US-20140329870-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND ISOTHIAZOLINONES | HSD17B12, COASY, UGT2B17 | TSHR 2916/4885CNR2 2867/4885NR1H2 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.