Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 2/20 | 0.43 |
| ▸ | HDAC11 known ✓ | Q96DB2 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 4/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2556211 | 1.00 | CES2 (0.52) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL540829 | 0.98 | CES2 (0.53) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL5533299 | 0.98 | CES2 (0.53) | CES2CES1MEN1FAAHMAPK1 | |
| Hydrochloric Acid SCHEMBL6565482 | 0.90 | TERT (0.53) | MEN1FAAHKMT2APPARGPPARD | |
| SCHEMBL23491293 | 0.88 | TERT (0.54) | MEN1FAAHKMT2APPARGPPARD | |
| SCHEMBL532716 | 0.88 | TERT (0.54) | MEN1FAAHKMT2APPARGPPARD | |
| SCHEMBL28532295 | 0.85 | CES2 (0.42) | CES2MEN1FAAHMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL16322648 | 0.83 | CES2 (0.50) | CES2CES1MEN1FAAHMAPK1 | |
| Sulfuric Acid SCHEMBL28836767 | 0.83 | TERT (0.49) | MEN1FAAHKMT2APPARGPPARD | |
| Sulfuric Acid SCHEMBL28836761 | 0.83 | TERT (0.49) | MEN1FAAHKMT2APPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 437 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12076432-B2 | Method of repairing oxidatively treated hair | CONOPCO, INC. (US) | 2024-09-03 | — | — | US | claimed |
| CN-114599334-A | Stable low pH personal care compositions and methods therefor | 高露洁-棕榄公司 | 2022-06-07 | — | — | CN | claimed |
| US-9295859-B2 | Porous, dissolvable solid substrate and surface resident coating comprising matrix microspheres | THE PROCTER & GAMBLE COMPANY (US) | 2016-03-29 | — | — | US | claimed |
| EP-1725298-B1 | HAIR CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2007-05-02 | — | — | EP | claimed |
| US-20070081965-A1 | Hair conditioning compositions | CONOPCO, INC., D/B/A UNILEVER | 2007-04-12 | — | — | US | claimed |
| EP-1725298-A1 | HAIR CONDITIONING COMPOSITIONS | Unilever Plc (GB) | 2006-11-29 | — | — | EP | claimed |
| WO-2005048961-A1 | HAIR CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2005-06-02 | — | — | WO | claimed |
| JP-8337969-A | — | — | None | — | — | JP | disclosed |
| US-12624319-B2 | Water disintegrable, foam producing article for use as a toilet bowl cleaner | THE PROCTER & GAMBLE COMPANY (US) | 2026-05-12 | — | — | US | disclosed |
| US-20250344929-A1 | Fibrous Structures Comprising Particles and Methods for Making Same | PROCTER & GAMBLE (US) | 2025-11-13 | — | — | US | disclosed |
| EP-4197598-B1 | ACTIVE AGENT-CONTAINING ARTICLES THAT EXHIBIT CONSUMER ACCEPTABLE ARTICLE IN-USE PROPERTIES | PROCTER & GAMBLE (US) | 2025-10-22 | — | — | EP | disclosed |
| US-12440083-B2 | Fibrous structures comprising particles and methods for making same | THE PROCTER & GAMBLE COMPANY (US) | 2025-10-14 | — | — | US | disclosed |
| US-12433834-B2 | Hair conditioning composition | CONOPCO, INC. (US) | 2025-10-07 | — | — | US | disclosed |
| US-20070081965-A1 | Hair conditioning compositions | CONOPCO, INC., D/B/A UNILEVER | 2007-04-12 | — | — | US | disclosed |
| EP-1725298-A1 | HAIR CONDITIONING COMPOSITIONS | Unilever Plc (GB) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005048961-A1 | HAIR CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2005-06-02 | — | — | WO | disclosed |
| US-6210660-B1 | ILEX RESIN IS MADE BY A METHOD COMPRISING EXTRACTING LEAVES OF ILEX AQUIFOLIUM OR ILEX PARAGUARIENSIS WITH A SEMIPOLAR OR APOLAR, WATER-FREE ORGANIC SOLVENT, EITHER CONTINUOUSLY OR IN SUCCESSIVE MULTIPLE EXTRACTION STEPS. | WELLA AKTIENGESELLSCHAFT (DE) | 2001-04-03 | — | — | US | disclosed |
| US-6117436-A | CONDITIONER AND EMULSIFIER WITH CATIONIC OR ANIONIC BASE; HAIR, SKIN | WELLA AKTIENGESELLSCHAFT (DE) | 2000-09-12 | — | — | US | disclosed |
| US-5958395-A | SMOOTHING OF THE HAIR SURFACE TO INCREASE LUSTER, GLOSS AND COLOR DEPTH BY APPLYING A HAIR CONDITIONER CONTAINING HOLLY (ILEX) LEAF RESIN OBTAINED BY HOT-EXTRACTION, HOT-FILTRATION, MIXING WITH FULLER'S EARTH; COSMETICS; SKIN PROTECTIVE FILMS | WELLA AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | disclosed |
| JP-H08337969-A | WATER-CONTAINING SOFTENING AND RINSING AGENT FOR TREATING FIBER PRODUCT | WELLA AG | 1996-12-24 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12440083-B2 | Fibrous structures comprising particles and methods for making same | FGB, CD68, SDCBP | PPARG 3780/4885HDAC11 3419/4885CES2 2307/4885 |
| US-12624319-B2 | Water disintegrable, foam producing article for use as a toilet bowl cleaner | SI, SMS, SMURF1 | PPARG 2247/4885HDAC11 2514/4885CES2 1318/4885 |
| US-20250344929-A1 | Fibrous Structures Comprising Particles and Methods for Making Same | FGB, CD68, SDCBP | PPARG 3780/4885HDAC11 3419/4885CES2 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.