Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 known ✓ | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MAOB known ✓ | P27338 | 2/20 | 0.34 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL395657 | 0.86 | CA4 (0.32) | LTA4H | |
| Hydrochloric Acid SCHEMBL5612735 | 0.86 | CA4 (0.32) | LTA4H | |
| Hydrochloric Acid SCHEMBL12815696 | 0.85 | MAOB (0.31) | MAOBMAOA | |
| SCHEMBL4097489 | 0.84 | CA4 (0.33) | LTA4H | |
| Hydrochloric Acid SCHEMBL12815820 | 0.82 | ACHE (0.42) | — | |
| Hydrochloric Acid SCHEMBL3190527 | 0.78 | CYP3A4 (0.36) | — | |
| Hydrochloric Acid SCHEMBL3182803 | 0.74 | LTA4H (0.33) | DHFRRXRARXRBLTA4HMAOB | |
| Hydrochloric Acid SCHEMBL7945862 | 0.72 | MAOA (0.34) | DHFRRXRARXRBLTA4HMAOB | |
| SCHEMBL5087699 | 0.72 | RXRA (0.38) | DHFRRXRARXRBLTA4HHRH3 | |
| Biphenyl SCHEMBL820134 | 0.71 | ALDH1A1 (0.39) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267908-A1 | Catalyst for olefin polymerization, process for producing olefin polymer, olefin copolymer, novel transition metal compound, and process for producing transition metal compound | MITSUI CHEMICALS, INC. | 2010-10-21 | — | — | US | disclosed |
| US-20070260026-A1 | Catalyst for Olefin Polymerization Process for Producing Olefin Polymer, Olefin Copolymer, Novel Transition Metal Compound, and Process for Producing Transition Metal Compound | MITSUI CHEMICALS, INC. | 2007-11-08 | — | — | US | disclosed |
| EP-1788002-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION, PROCESS FOR PRODUCTION OF OLEFIN POLYMERS, OLEFIN COPOLYMERS, NOVEL TRANSITION METAL COMPOUNDS, AND PROCESS FOR PRODUCTION OF TRANSITION METAL COMPOUNDS | Mitsui Chemicals, Inc. (JP) | 2007-05-23 | — | — | EP | disclosed |
| US-20020072561-A1 | OLEFIN-BASED COPOLYMER COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-13 | — | — | US | disclosed |
| EP-0842955-B1 | Propylene-1-butene copolymer | SUMITOMO CHEMICAL CO (JP) | 2002-05-22 | — | — | EP | disclosed |
| US-6331593-B1 | POLYOLEFIN RESIN AND OLEFIN COPOLYMER CONTAINING CYCLIC OLEFIN AND TWO OR OLEFINS INCLUDING ETHYLENE, PROPYLENE AND ANOTHER ALPHA-OLEFIN | SUMITOMO CHEMICAL LIMITED., CO. (JP) | 2001-12-18 | — | — | US | disclosed |
| US-6300447-B1 | Ethylene-α-olefin-nonconjugated polyene random copolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-10-09 | — | — | US | disclosed |
| US-6288191-B1 | TRANSITION METAL CATALYST COMPLEX INCLUDES ORGANOALUMINUM AND ORGANOBORON COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-09-11 | — | — | US | disclosed |
| CN-1266068-A | Copolymer of ethylene-alkene aromatic compound, its production method and moulding products | SUMITOMO CHEMICAL CO (JP) | 2000-09-13 | — | — | CN | disclosed |
| US-6084048-A | SPECIFIED 1-BUTENE-PROPYLENE COPOLYMER WITH NO CRYSTALLINE MELTING PEAK AND NO CRYSTALLIZATION PEAK ACCORDING TO A DIFFERENTIAL SCANNING CALORIMETER MEASUREMENT; BLENDS WITH POLYOLEFINS HAVING FLEXIBILITY, ELONGATION, WEAR RESISTANCE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0842955-A2 | Propylene-1-butene copolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267908-A1 | Catalyst for olefin polymerization, process for producing olefin polymer, olefin copolymer, novel transition metal compound, and process for producing transition metal compound | RB1, POF1B, CCNA1 | HRH3 558/4885MAOB 602/4885MAOA 344/4885 |
| US-20070260026-A1 | Catalyst for Olefin Polymerization Process for Producing Olefin Polymer, Olefin Copolymer, Novel Transition Metal Compound, and Process for Producing Transition Metal Compound | POF1B, RB1, CCNA1 | HRH3 658/4885MAOB 619/4885MAOA 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.