SCHEMBL318905

SCHEMBL318905

OC(c1cc[c]cc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.45
TSHR P16473 1/20 0.44
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
LMNA P02545 4/20 0.41
MAPK1 P28482 1/20 0.41
PGR P06401 1/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 2/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8207275 0.85 KDM4E (0.48) TSHRLMNAMEN1CYP2C9KMT2A
Diphenylmethanol SCHEMBL11564700 0.84 SMN1; SMN2 (0.61) SMN1; SMN2L3MBTL1TSHRCA12CA1
Diphenylmethanol SCHEMBL41571 0.84 SMN1; SMN2 (0.61) SMN1; SMN2L3MBTL1TSHRCA12CA1
Diphenylmethanol SCHEMBL6434457 0.84 SMN1; SMN2 (0.61) SMN1; SMN2L3MBTL1TSHRCA12CA1
Diphenylmethanol SCHEMBL10868602 0.84 SMN1; SMN2 (0.61) SMN1; SMN2L3MBTL1TSHRCA12CA1
Diphenylmethanol SCHEMBL8164003 0.81 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1TSHRCA12CA1
SCHEMBL8671295 0.81 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1TSHRCA12CA1
Diphenylmethanol SCHEMBL9324200 0.81 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1TSHRCA12CA1
Diphenylmethanol SCHEMBL15641329 0.81 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1TSHRCA12CA1
Diphenylmethanol SCHEMBL29571414 0.81 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1TSHRCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365485-B2 Substituted arylcyclopentenes as therapeutic agents ALLERGAN, INC. (US) 2016-06-14 US claimed
CN-103508838-B Preparation method of diphenylmethane compounds DALIAN CHEMICAL PHYSICS INST 2015-01-14 CN claimed
US-20140323510-A1 SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS ALLERGAN, INC. (US) 2014-10-30 US claimed
US-8722726-B2 Substituted arylcyclopentenes as therapeutic agents ALLERGAN, INC. (US) 2014-05-13 US claimed
EP-2118094-B1 GAMMA-LACTAMS FOR THE TREATMENT OF GLAUCOMA OR ELEVATED INTRAOCULAR PRESSURE ALLERGAN INC (US) 2013-04-17 EP claimed
EP-2257548-B1 THERAPEUTIC COMPOUNDS ALLERGAN INC (US) 2012-12-26 EP claimed
US-7956051-B2 Therapeutic amides and related compounds ALLERGAN, INC. (US) 2011-06-07 US claimed
EP-2247583-A1 HYDRAZINES IN GLAUCOMA THERAPY ALLERGAN, INC. (US) 2010-11-10 EP claimed
US-20100137347-A1 SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS ALLERGAN, INC. (US) 2010-06-03 US claimed
EP-2121609-A1 SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS Allergan, Inc. (US) 2009-11-25 EP claimed
WO-2009094286-A1 HYDRAZINES IN GLAUCOMA THERAPY ALLERGAN, INC. (US) 2009-07-30 WO claimed
US-20090192151-A1 THERAPEUTIC AMIDES AND RELATED COMPOUNDS ALLERGAN, INC. 2009-07-30 US claimed
WO-2008091818-A1 SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS ALLERGAN, INC. (US) 2008-07-31 WO claimed
US-4791126-A Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredients ONO PHARMACEUTICAL CO., LTD. (JP) 1988-12-13 US claimed
EP-0133103-B1 BENZYL-PHENYL OSIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOURNIER INNOVATION ET SYNERGIE (FR) 1987-11-11 EP claimed
US-4598068-A Benzylphenyl osides, method of preparation and use therefor Societe de Recheres Industrielles (FR) 1986-07-01 US claimed
EP-0047109-B1 RHODANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND ALDOSE REDUCTASE INHIBITOR CONTAINING THE RHODANINE DERIVATIVES AS ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 1985-01-02 EP claimed
US-4463004-A ANALGESICS DELALANDE S.A. (FR) 1984-07-31 US claimed
EP-0047109-A1 Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 1982-03-10 EP claimed
JP-56167766-A None JP disclosed
CN-110372777-A A kind of liquid-phase synthesis process carrying out target polypeptides based on phosphorous small molecule carrier PSS 西北工业大学 2019-10-25 CN disclosed
US-9796696-B2 Substituted arylcyclopentenes as therapeutic agents ALLERGAN, INC. (US) 2017-10-24 US disclosed
EP-2027081-B1 THERAPEUTIC PROSTAGLANDIN COMPOUNDS FOR THE TREATMENT OF GLAUCOMA ALLERGAN INC (US) 2017-05-03 EP disclosed
EP-2285775-B1 Lactams and their use in the treatment of inter alia ocular hypertension or baldness ALLERGAN INC (US) 2017-03-22 EP disclosed
US-20170057941-A1 SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS ALLERGAN, INC. 2017-03-02 US disclosed
US-9365485-B2 Substituted arylcyclopentenes as therapeutic agents ALLERGAN, INC. (US) 2016-06-14 US disclosed
CN-105315120-A Method for benzene and methanol alkylation reaction CHINA PETROLEUM & CHEMICAL 2016-02-10 CN disclosed
CN-105272797-A Benzene and methanol alkylation reaction method CHINA PETROLEUM & CHEMICAL 2016-01-27 CN disclosed
US-20150274658-A1 THERAPEUTIC LACTAMS ALLERGAN, INC. (US) 2015-10-01 US disclosed
EP-2845849-A1 Therapeutic cyclopentane derivatives ALLERGAN, INC. (US) 2015-03-11 EP disclosed
US-20140323510-A1 SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS ALLERGAN, INC. (US) 2014-10-30 US disclosed
EP-2021323-B1 THERAPEUTIC CYCLOPENTANE DERIVATIVES ALLERGAN INC (US) 2014-07-09 EP disclosed
US-8772507-B2 Imidazole-benzamide anti-cancer agents CYTOKINETICS, INC. (US) 2014-07-08 US disclosed
US-8722726-B2 Substituted arylcyclopentenes as therapeutic agents ALLERGAN, INC. (US) 2014-05-13 US disclosed
US-8633310-B2 Therapeutic substituted lactams ALLERGAN, INC. (US) 2014-01-21 US disclosed
US-20130261130-A1 NEUROTRYPSIN INHIBITORS NEUROTUNE AG (CH) 2013-10-03 US disclosed
EP-2635559-A2 NEUROTRYPSIN INHIBITORS Neurotune AG (CH) 2013-09-11 EP disclosed
US-8530471-B2 Therapeutic cyclopentane derivatives ALLERGAN, INC. (US) 2013-09-10 US disclosed
US-20130231322-A1 THERAPEUTIC SUBSTITUTED BETA-LACTAMS ALLERGAN, INC. (US) 2013-09-05 US disclosed
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
US-8440819-B2 Therapeutic substituted beta-lactams ALLERGAN, INC. (US) 2013-05-14 US disclosed
US-20130096315-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS QIAN XIANGPING (US) 2013-04-18 US disclosed
EP-2118094-B1 GAMMA-LACTAMS FOR THE TREATMENT OF GLAUCOMA OR ELEVATED INTRAOCULAR PRESSURE ALLERGAN INC (US) 2013-04-17 EP disclosed
US-8362054-B2 Therapeutic substituted lactams ALLERGAN, INC. (US) 2013-01-29 US disclosed
CN-101522669-B Therapeutic lactams ALLERGAN INC 2013-01-16 CN disclosed
EP-2331521-B1 COMPOUNDS FOR GROWING HAIR ALLERGAN INC (US) 2013-01-02 EP disclosed
EP-2257548-B1 THERAPEUTIC COMPOUNDS ALLERGAN INC (US) 2012-12-26 EP disclosed
EP-2019820-B1 THERAPEUTIC PYRROLIDINE COMPOUNDS ALLERGAN INC (US) 2012-11-21 EP disclosed
US-20120283287-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS QIAN XIANGPING (US) 2012-11-08 US disclosed
US-8278347-B2 Therapeutic compounds ALLERGAN, INC. (US) 2012-10-02 US disclosed
US-8263593-B2 Therapeutic compounds ALLERGAN, INC. (US) 2012-09-11 US disclosed
US-8207340-B2 Imidazopyridinyl benzamide mitotic kinesin inhibitors CYTOKINETICS, INCORPORATED (US) 2012-06-26 US disclosed
US-8198318-B2 Therapeutic amides ALLERGEN, INC. (US) 2012-06-12 US disclosed
WO-2012059442-A2 NEUROTRYPSIN INHIBITORS NEUROTUNE AG (CH) 2012-05-10 WO disclosed
US-8163919-B2 Imidazopyridinyl benzamide mitotic kinesin inhibitors CYTOKINETICS, INCORPORATED (US) 2012-04-24 US disclosed
US-8124648-B2 Therapeutic lactams ALLERGAN, INC. (US) 2012-02-28 US disclosed
US-8093282-B2 Therapeutic N-aryl or N-heteroaryl pyrazolidine and pyrazolidinone derivatives ALLERGAN, INC. (US) 2012-01-10 US disclosed
US-20110263692-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. (US) 2011-10-27 US disclosed
US-8003678-B2 Therapeutic substituted thiazolidinones, oxazolidinones, and related compounds ALLERGAN, INC. (US) 2011-08-23 US disclosed
CN-101084181-B Preparation method of aromatic polycarbonate ASAHI CHEMICAL IND (JP) 2011-07-27 CN disclosed
US-7985767-B2 Glaucoma or ocular hypertension; selective prostaglandin EP2 agonists; carboxy-functional amides or sulfonamide and carboxy bioisosteres thereof; 5-(-3-(N-(4-(1-hydroxyhexyl)phenyl)acetamido)butyl)thiophene-2-carboxylic acid for example ALLERGAN, INC. (US) 2011-07-26 US disclosed
US-20110152255-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. 2011-06-23 US disclosed
US-7964596-B2 Therapeutic compounds ALLERGAN, INC. (US) 2011-06-21 US disclosed
US-7964599-B2 Therapeutic compounds ALLERGAN, INC. (US) 2011-06-21 US disclosed
US-7964634-B2 Therapeutic compounds ALLERGAN, INC. (US) 2011-06-21 US disclosed
EP-2331521-A1 THERAPEUTIC COMPOUNDS Allergan, Inc. (US) 2011-06-15 EP disclosed
US-7960379-B2 Therapeutic compounds ALLERGAN, INC. (US) 2011-06-14 US disclosed
CN-102089285-A Therapeutic N-aryl or N-heteroaryl pyrazolidine and pyrazolidinone derivatives ALLERGAN INC 2011-06-08 CN disclosed
CN-102089295-A Therapeutic substituted thiazolidinones, oxazolidinones, and related compounds ALLERGAN INC 2011-06-08 CN disclosed
US-7956051-B2 Therapeutic amides and related compounds ALLERGAN, INC. (US) 2011-06-07 US disclosed
CN-102083807-A Therapeutic compounds ALLERGAN INC 2011-06-01 CN disclosed
US-20110112166-A1 THERAPEUTIC CYCLOPENTANE DERIVATIVES ALLERGAN, INC (US) 2011-05-12 US disclosed
EP-2027082-B1 12-ARYL PROSTAGLANDIN ANALOGS ALLERGAN INC (US) 2011-04-20 EP disclosed
EP-2303836-A1 THERAPEUTIC CYCLOPENTANE DERIVATIVES Allergan, Inc. (US) 2011-04-06 EP disclosed
EP-2300439-A1 THERAPEUTIC SUBSTITUTED HYDANTOINS, AND RELATED COMPOUNDS Allergan, Inc. (US) 2011-03-30 EP disclosed
EP-2297084-A1 THERAPEUTIC COMPOUNDS Allergan, Inc. (US) 2011-03-23 EP disclosed
EP-2049467-B1 THERAPEUTIC AMIDES AND RELATED COMPOUNDS ALLERGAN INC (US) 2011-03-23 EP disclosed
US-7897629-B2 Therapeutic compounds ALLERGAN, INC. (US) 2011-03-01 US disclosed
EP-2285796-A1 THERAPEUTIC SUBSTITUTED THIAZOLIDINONES, OXAZOLIDINONES, AND RELATED COMPOUNDS Allergan, Inc. (US) 2011-02-23 EP disclosed
EP-2285790-A1 THERAPEUTIC COMPOUNDS Allergan, Inc. (US) 2011-02-23 EP disclosed
EP-2285775-A1 THERAPEUTIC LACTAMS Allergan, Inc. (US) 2011-02-23 EP disclosed
EP-2285782-A2 THERAPEUTIC N-ARYL OR N-HETEROARYL PYRAZOLIDINE AND PYRAZOLIDINONE DERIVATIVES Allergan, Inc. (US) 2011-02-23 EP disclosed
EP-2257548-A1 THERAPEUTIC COMPOUNDS Allergan, Inc. (US) 2010-12-08 EP disclosed
EP-2247583-A1 HYDRAZINES IN GLAUCOMA THERAPY ALLERGAN, INC. (US) 2010-11-10 EP disclosed
US-7795287-B2 Therapeutic substituted hydantoins and related compounds ALLERGAN, INC. (US) 2010-09-14 US disclosed
US-7795448-B2 Imidazoyl-benzamide anti-cancer agents CYTOKINETICS, INCORPORATED (US) 2010-09-14 US disclosed
US-7786150-B2 Therapeutic compounds OLD DAVID W 2010-08-31 US disclosed
US-7786117-B2 Therapeutic substituted thiazolidinones, oxazolidinones, and related compounds ALLERGAN, INC. (US) 2010-08-31 US disclosed
US-20100168189-A1 THERAPEUTIC SUBSTITUTED LACTAMS ALLERGAN, INC. 2010-07-01 US disclosed
US-20100137347-A1 SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS ALLERGAN, INC. (US) 2010-06-03 US disclosed
US-7713967-B2 5-(3-(3-(4-hexanoylphenyl)-2,5-dioxoimidazolidin-4-yl)propyl)thiophene-2-carboxylic acid; prostaglandin agonist; ocular hypotensive agent; post-sergical and post-laser trabeculectomy ocular hypertensive episodes, glaucoma, and as presurgical adjuncts ALLERGAN, INC. (US) 2010-05-11 US disclosed
US-7713968-B2 Substituted arylcyclopentenes as therapeutic agents ALLERGAN, INC. (US) 2010-05-11 US disclosed
US-7700627-B2 Therapeutic substituted lactams ALLERGAN, INC. (US) 2010-04-20 US disclosed
US-20100093809-A1 THERAPEUTIC SUBSTITUTED THIAZOLIDINONES, OXAZOLIDINONES, AND RELATED COMPOUNDS ALLERGAN, INC. (US) 2010-04-15 US disclosed
WO-2010019536-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. (US) 2010-02-18 WO disclosed
US-7659295-B2 5-(3-(3-(4-(1-hydroxyhexyl)phenyl)-4-oxo-thiazolidin-2-yl)propyl)thiophene-2-carboxylic acid; prostaglandin agonist; ocular hypotensive agents; post-surgical and post-laser trabeculectomy ocular hypertensive episodes, glaucoma, and as presurgical adjuncts ALLERGAN, INC. (US) 2010-02-09 US disclosed
US-20090318449-A1 THERAPEUTIC LACTAMS ALLERGAN, INC. (US) 2009-12-24 US disclosed
US-20090312365-A1 Certain Chemical Entities, Compositions, and Methods CYTOKINETICS, INC. 2009-12-17 US disclosed
US-20090306127-A1 Certain Chemical Entities, Compositions and Methods CYTOKINETICS, INC 2009-12-10 US disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
WO-2009142969-A1 THERAPEUTIC LACTAMS ALLERGAN, INC. (US) 2009-11-26 WO disclosed
US-20090286841-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS CYTOKINETICS, INC. 2009-11-19 US disclosed
US-7618981-B2 to treat cellular proliferative diseases, hyperplasias, solid tumor, cardiac hypertrophy, immune disorders and inflammation; modulators of one or more mitotic kinesins; N-(2-(2-dimethylamino-acetylamino)-1-{4-[8-(1-hydroxy-ethyl)-imidazo[1,2-a]pyridin-2-yl]-benzyl}-ethyl)-3-chloro-4-isopropoxy-benzamide CYTOKINETICS, INC. (US) 2009-11-17 US disclosed
US-20090281104-A1 Therapeutic Compounds ALLERGAN, INC. (US) 2009-11-12 US disclosed
WO-2009137413-A1 THERAPEUTIC CYCLOPENTANE DERIVATIVES ALLERGAN, INC. (US) 2009-11-12 WO disclosed
WO-2009137345-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. (US) 2009-11-12 WO disclosed
WO-2009137339-A2 THERAPEUTIC N-ARYL OR N-HETEROARYL PYRAZOLIDINE AND PYRAZOLIDINONE DERIVATIVES ALLERGAN, INC. (US) 2009-11-12 WO disclosed
WO-2009137343-A1 THERAPEUTIC SUBSTITUTED HYDANTOINS, AND RELATED COMPOUNDS ALLERGAN, INC. (US) 2009-11-12 WO disclosed
WO-2009137544-A1 THERAPEUTIC SUBSTITUTED THIAZOLIDINONES, OXAZOLIDINONES, AND RELATED COMPOUNDS ALLERGAN, INC. (US) 2009-11-12 WO disclosed
US-20090281101-A1 THERAPEUTIC SUBSTITUTED HYDANTOINS, AND RELATED COMPOUNDS ALLERGAN, INC. (US) 2009-11-12 US disclosed
US-20090281102-A1 THERAPEUTIC N-ARYL OR N-HETEROARYL PYRAZOLIDINE AND PYRAZOLIDINONE DERIVATIVES ALLERGAN, INC. (US) 2009-11-12 US disclosed
US-20090281171-A1 THERAPEUTIC SUBSTITUTED THIAZOLIDINONES, OXAZOLIDINONES, AND RELATED COMPOUNDS ALLERGAN, INC. (US) 2009-11-12 US disclosed
US-20090275646-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. (US) 2009-11-05 US disclosed
US-20090270387-A1 SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS ALLERGAN, INC. (US) 2009-10-29 US disclosed
WO-2009131977-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. (US) 2009-10-29 WO disclosed
US-20090247594-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. (US) 2009-10-01 US disclosed
WO-2009117378-A2 THERAPEUTIC AMIDES ALLERGAN, INC. (US) 2009-09-24 WO disclosed
US-20090239858-A1 THERAPEUTIC AMIDES ALLERGAN, INC. (US) 2009-09-24 US disclosed
WO-2009114744-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. (US) 2009-09-17 WO disclosed
WO-2009114467-A1 THERAPEUTIC CYCLOPENTANE DERIVATIVES ALLERGAN, INC. (US) 2009-09-17 WO disclosed
WO-2009114307-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. (US) 2009-09-17 WO disclosed
US-20090233931-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. 2009-09-17 US disclosed
US-20090233921-A1 THERAPEUTIC CYCLOPENTANE DERIVATIVES ALLERGAN, INC. (US) 2009-09-17 US disclosed
US-20090227636-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. (US) 2009-09-10 US disclosed
US-20090227635-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. (US) 2009-09-10 US disclosed
CN-101522669-A Therapeutic lactams ALLERGAN INC (US) 2009-09-02 CN disclosed
WO-2009105440-A1 BETA-LACTAMS FOR REDUCING INTRAOCULAR PRESSURE ALLERGAN, INC. (US) 2009-08-27 WO disclosed
WO-2009105438-A1 THERAPEUTIC SUBSTITUTED LACTAMS ALLERGAN, INC. (US) 2009-08-27 WO disclosed
US-20090215740-A1 THERAPEUTIC SUBSTITUTED BETA-LACTAMS ALLERGAN, INC. (US) 2009-08-27 US disclosed
US-20090209538-A1 THERAPEUTIC SUBSTITUTED LACTAMS ALLERGAN, INC. (US) 2009-08-20 US disclosed
US-7576112-B2 Therapeutic N-aryl or N-heteroaryl pyrazolidine and pyrazolidinone derivatives ALLERGAN, INC. (US) 2009-08-18 US disclosed
WO-2009094286-A1 HYDRAZINES IN GLAUCOMA THERAPY ALLERGAN, INC. (US) 2009-07-30 WO disclosed
US-20090192151-A1 THERAPEUTIC AMIDES AND RELATED COMPOUNDS ALLERGAN, INC. 2009-07-30 US disclosed
US-7557095-B2 Therapeutic compounds ALLERGAN, INC. (US) 2009-07-07 US disclosed
US-20090163560-A1 THERAPEUTIC N-ARYL OR N-HETEROARYL PYRAZOLIDINE AND PYRAZOLIDINONE DERIVATIVES OLD DAVID W 2009-06-25 US disclosed
US-7550448-B2 Glaucoma; 3-halopyrrolidine compounds; prostaglandin EP2 receptor modulators ALLERGAN, INC. (US) 2009-06-23 US disclosed
US-7547727-B2 Therapeutic cyclopentane derivatives ALLERGAN, INC. (US) 2009-06-16 US disclosed
EP-2066660-A2 THERAPEUTIC LACTAMS Allergan, Inc. (US) 2009-06-10 EP disclosed
EP-2057128-A2 THERAPEUTIC SUBSTITUTED HYDANTOINS AND RELATED COMPOUNDS Allergan, Inc. (US) 2009-05-13 EP disclosed
EP-2054409-A2 THERAPEUTIC SUBSTITUTED THIAZOLIDINONES, OXAZOLIDINONES, AND RELATED COMPOUNDS Allergan, Inc. (US) 2009-05-06 EP disclosed
EP-2049495-A2 N-ARYL OR N-HETEROARYL PYRAZOLIDINE AND PYRAZOLIDINONE DERIVATIVES AS PROSTAGLANDINE RECEPTOR INHIBITORS Allergan, Inc. (US) 2009-04-22 EP disclosed
EP-2049467-A2 THERAPEUTIC AMIDES AND RELATED COMPOUNDS Allergan, Inc. (US) 2009-04-22 EP disclosed
US-20090099249-A1 THERAPEUTIC LACTAMS ALLERGAN, INC. 2009-04-16 US disclosed
EP-2044041-A2 ISOTHIAZOLIDINES USEFUL IN THE TREATMENT OF OCULAR HYPERTENSIVE CONDITIONS Allergan, Inc. (US) 2009-04-08 EP disclosed
US-7507833-B2 Therapeutic N-aryl or N-heteroaryl pyrazolidine and pyrazolidinone derivatives ALLERGAN, INC. (US) 2009-03-24 US disclosed
EP-2029518-A2 CYCLOPENTANE-DERIVATIVES AND THEIR USE AS OCULAR HYPOTENSIVE AGENTS Allergan, Inc. (US) 2009-03-04 EP disclosed
US-7498447-B2 Treating eye diseases including glaucoma or ocular hypertension; selective prostaglandin EP2 agonists; acid-functional aryl substituted pyrrolidine compounds ALLERGAN, INC. (US) 2009-03-03 US disclosed
EP-2027081-A2 THERAPEUTIC PROSTAGLANDIN COMPOUNDS FOR THE TREATMENT OF GLAUCOMA Allergan, Inc. (US) 2009-02-25 EP disclosed
EP-2027082-A1 12-ARYL OR HETEROARYL PROSTAGLANDIN ANALOGS Allergan, Inc. (US) 2009-02-25 EP disclosed
US-7491844-B2 Therapeutic cyclopentane derivatives ALLERGAN, INC. (US) 2009-02-17 US disclosed
EP-2021322-A2 THERAPEUTIC CYCLOPENTANE DERIVATIVES Allergan, Inc. (US) 2009-02-11 EP disclosed
EP-2021323-A2 THERAPEUTIC CYCLOPENTANE DERIVATIVES Allergan, Inc. (US) 2009-02-11 EP disclosed
EP-2019820-A1 THERAPEUTIC PYRROLIDINE COMPOUNDS Allergan, Inc. (US) 2009-02-04 EP disclosed
US-7482475-B2 Therapeutic lactams ALLERGAN, INC. (US) 2009-01-27 US disclosed
US-20090016981-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. (US) 2009-01-15 US disclosed
US-7476755-B2 Therapeutic compounds ALLERGAN, INC. (US) 2009-01-13 US disclosed
WO-2007131012-A9 12-ARYL OR HETEROARYL PROSTAGLANDIN ANALOGS ALLERGAN INC (US) 2009-01-08 WO disclosed
US-7468360-B2 Therapeutic amides and related compounds ALLERGAN, INC. (US) 2008-12-23 US disclosed
US-7439372-B2 Therapeutic compounds ALLERGAN, INC. (US) 2008-10-21 US disclosed
US-20080255182-A1 Certain chemical entities, compositions, and methods CYTOKINETICS, INC. 2008-10-16 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
US-20080119539-A1 THERAPEUTIC AMIDES ALLERGAN, INC. 2008-05-22 US disclosed
US-20080058387-A1 5-(3-(3-(4-(1-hydroxyhexyl)phenyl)-4-oxo-thiazolidin-2-yl)propyl)thiophene-2-carboxylic acid; prostaglandin agonist; ocular hypotensive agents; post-surgical and post-laser trabeculectomy ocular hypertensive episodes, glaucoma, and as presurgical adjuncts ALLERGAN, INC. 2008-03-06 US disclosed
US-20080058397-A1 5-(3-(3-(4-hexanoylphenyl)-2,5-dioxoimidazolidin-4-yl)propyl)thiophene-2-carboxylic acid; prostaglandin agonist; ocular hypotensive agent; post-sergical and post-laser trabeculectomy ocular hypertensive episodes, glaucoma, and as presurgical adjuncts OLD DAVID W 2008-03-06 US disclosed
WO-2008028032-A2 THERAPEUTIC SUBSTITUTED HYDANTOINS AND RELATED COMPOUNDS ALLERGAN, INC. (US) 2008-03-06 WO disclosed
US-20080051374-A1 Therapeutic Amides and related Compounds ALLERGAN, INC. 2008-02-28 US disclosed
WO-2008024765-A2 THERAPEUTIC SUBSTITUTED THIAZOLIDINONES, OXAZOLIDINONES, AND RELATED COMPOUNDS ALLERGAN, INC. (US) 2008-02-28 WO disclosed
WO-2008021975-A2 THERAPEUTIC LACTAMS ALLERGAN, INC. (US) 2008-02-21 WO disclosed
US-20080045576-A1 THERAPEUTIC N-ARYL OR N-HETEROARYL PYRAZOLIDINE AND PYRAZOLIDINONE DERIVATIVES ALLERGAN, INC. 2008-02-21 US disclosed
WO-2008021933-A2 N-ARYL OR N-HETEROARYL PYRAZOLIDINE AND PYRAZOLIDINONE DERIVATIVES AS PROSTAGLANDINE RECEPTOR INHIBITORS ALLERGAN, INC. (US) 2008-02-21 WO disclosed
WO-2008021804-A2 THERAPEUTIC AMIDES AND RELATED COMPOUNDS ALLERGAN, INC. (US) 2008-02-21 WO disclosed
US-20080039505-A1 THERAPEUTIC LACTAMS ALLERGAN, INC. 2008-02-14 US disclosed
US-20080033023-A1 Treating eye diseases including glaucoma or ocular hypertension; selective prostaglandin EP2 agonists; acid-functional aryl substituted pyrrolidine compounds OLD DAVID W 2008-02-07 US disclosed
US-20080027108-A1 THERAPEUTIC SUBSTITUTED LACTAMS ALLERGAN, INC. 2008-01-31 US disclosed
WO-2007140197-A1 THERAPEUTIC PYRROLIDINE COMPOUNDS ALLERGAN, INC. (US) 2007-12-06 WO disclosed
WO-2007140136-A2 THERAPEUTIC CYCLOPENTANE DERIVATIVES ALLERGAN, INC. (US) 2007-12-06 WO disclosed
US-20070281981-A1 Glaucoma; 3-substituted pyrrolidine compounds; prostaglandin receptor modulators ALLERGAN, INC. 2007-12-06 US disclosed
CN-101084181-A Asahi chemical corp (jp) ASAHI CHEMICAL CORP (JP) 2007-12-05 CN disclosed
US-20070270387-A1 THERAPEUTIC CYCLOPENTANE DERIVATIVES ALLERGAN, INC 2007-11-22 US disclosed
WO-2007134085-A2 ISOTHIAZOLIDINES USEFUL IN THE TREATMENT OF OCULAR HYPERTENSIVE CONDITIONS ALLERGAN, INC. (US) 2007-11-22 WO disclosed
US-20070265321-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. 2007-11-15 US disclosed
WO-2007130890-A2 CYCLOPENTANE-DERIVATIVES AND THEIR USE AS OCULAR HYPOTENSIVE AGENTS ALLERGAN, INC. (US) 2007-11-15 WO disclosed
WO-2007130902-A2 THERAPEUTIC CYCLOPENTANE DERIVATIVES ALLERGAN, INC. (US) 2007-11-15 WO disclosed
WO-2007131012-A1 12-ARYL OR HETEROARYL PROSTAGLANDIN ANALOGS ALLERGAN, INC. (US) 2007-11-15 WO disclosed
US-20070259929-A1 Therapeutic Compounds ALLERGAN, INC. 2007-11-08 US disclosed
US-20070259947-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. 2007-11-08 US disclosed
US-20070259836-A1 THERAPEUTIC CYCLOPENTANE DERIVATIVES ALLERGAN, INC. 2007-11-08 US disclosed
WO-2007115020-A2 THERAPEUTIC PROSTAGLANDIN COMPOUNDS FOR THE TREATMENT OF GLAUCOMA ALLERGAN, INC. (US) 2007-10-11 WO disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
US-20070197481-A1 Certain chemical entities, compositions, and methods CYTOKINETICS, INCORPORATED 2007-08-23 US disclosed
EP-1633733-A4 CANNABINOID DERIVATIVES, METHODS OF MAKING, AND USE THEREOF UNIV TENNESSEE RES CORP (US) 2007-02-28 EP disclosed
US-20060247289-A1 Certain chemical entities, compositions, and methods CYTOKINETICS, INCORPORATED 2006-11-02 US disclosed
US-20060094708-A1 to treat cellular proliferative diseases, hyperplasias, solid tumor, cardiac hypertrophy, immune disorders and inflammation; modulators of one or more mitotic kinesins; N-(2-(2-dimethylamino-acetylamino)-1-{4-[8-(1-hydroxy-ethyl)-imidazo[1,2-a]pyridin-2-yl]-benzyl}-ethyl)-3-chloro-4-isopropoxy-benzamide CYTOKINETICS, INCORPORATED 2006-05-04 US disclosed
EP-1633733-A1 CANNABINOID DERIVATIVES, METHODS OF MAKING, AND USE THEREOF THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) 2006-03-15 EP disclosed
WO-2004113320-A1 CANNABINOID DERIVATIVES, METHODS OF MAKING, AND USE THEREOF THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2004-12-29 WO disclosed
EP-0991619-B1 INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION TANABE SEIYAKU CO (JP) 2003-09-10 EP disclosed
US-6596752-B1 Small molecules that are potent inhibitors of alpha 4 beta 1 mediated adhesion to either VCAM or CS-1 and which could be useful for the treatment of inflammatory diseases. TANABE SEIYAKU CO., LTD. (JP) 2003-07-22 US disclosed
US-20030130349-A1 Inhibitors of alpha 4beta1 mediated cell adhesion TANABE SEIYAKU CO., LTD. 2003-07-10 US disclosed
US-6482849-B1 Inhibitors of α4β1 mediated cell adhesion TANABE SEIYAKU CO., LTD. (JP) 2002-11-19 US disclosed
EP-1090017-B1 NOVEL COMPOUNDS DERIVED FROM ALPHA-D-XYLOSE, PREPARATION METHOD AND THERAPEUTIC USE FOURNIER IND & SANTE (FR) 2002-10-30 EP disclosed
US-6291433-B1 Derivatives of α-D-Thioxyloside and their use against atheroma FOURNIER INDUSTRIE ET SANTE (FR) 2001-09-18 US disclosed
EP-1090017-A1 NOVEL COMPOUNDS DERIVED FROM $g(a)-D-XYLOSE, PREPARATION METHOD AND THERAPEUTIC USE FOURNIER INDUSTRIE ET SANTE (FR) 2001-04-11 EP disclosed
EP-0991619-A1 INHIBITORS OF $g(a) 4?$g(b) 1?MEDIATED CELL ADHESION TANABE SEIYAKU CO., LTD. (JP) 2000-04-12 EP disclosed
WO-1999067261-A1 NOVEL COMPOUNDS DERIVED FROM α-D-XYLOSE, PREPARATION METHOD AND THERAPEUTIC USE FOURNIER INDUSTRIE ET SANTE (FR) 1999-12-29 WO disclosed
WO-1998058902-A1 INHIBITORS OF α4β1MEDIATED CELL ADHESION TANABE SEIYAKU CO., LTD. (JP) 1998-12-30 WO disclosed
CN-1027268-C Process for preparing benzopyrone-beta-D-thioxylosides FOURNIER IND & SANTE (FR) 1995-01-04 CN disclosed
CN-1024801-C Process for preparing beta-D-phenyl-thioxylosides and their use FOURNIER INNOVATION SYNERGIE (FR) 1994-06-01 CN disclosed
CN-1020614-C METHOD FOR PREPARING BETA-D-PHENYL-THIOXYLOSIDE FOURNIER INNOVATION SYNERGIE (FR) 1993-05-12 CN disclosed
CN-1050544-A Novel benzopyrone-β-D-sulfo-xyloside, their preparation method and the application in treatment thereof FOURNIER IND & SANTE (FR) 1991-04-10 CN disclosed
EP-0367671-A2 Novel beta-D-phenylthioxylosides, their method of preparation and their use as pharmaceuticals FOURNIER INDUSTRIE ET SANTE (FR) 1990-05-09 EP disclosed
CN-1041948-A New this glucosides of B-D-phenyl sulfo-and preparation method thereof and therepic use FOURNIER INNOVATION SYNERGIE (FR) 1990-05-09 CN disclosed
US-4831045-A Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US disclosed
CN-88102569-A Novel beta-D-phenyl-thioxylosides, process for their preparation and their use in medical treatment 1988-12-14 CN disclosed
US-4791126-A Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredients ONO PHARMACEUTICAL CO., LTD. (JP) 1988-12-13 US disclosed
US-4598068-A Benzylphenyl osides, method of preparation and use therefor Societe de Recheres Industrielles (FR) 1986-07-01 US disclosed
US-4598068-A Benzylphenyl osides, method of preparation and use therefor Societe de Recheres Industrielles (FR) 1986-07-01 US disclosed
EP-0047109-B1 RHODANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND ALDOSE REDUCTASE INHIBITOR CONTAINING THE RHODANINE DERIVATIVES AS ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 1985-01-02 EP disclosed
US-4464382-A Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 1984-08-07 US disclosed
US-4463004-A ANALGESICS DELALANDE S.A. (FR) 1984-07-31 US disclosed
US-4463004-A ANALGESICS DELALANDE S.A. (FR) 1984-07-31 US disclosed
EP-0051023-B1 DERIVATIVES OF THE BENZOYL AND ALPHA HYDROXYBENZYL-PHENYL OSIDES FAMILY, METHOD FOR THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. Société anonyme dite: (FR) 1984-05-30 EP disclosed
EP-0047109-A1 Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 1982-03-10 EP disclosed
JP-S56167766-A HIGHLY THICK COAT-TYPE PAINT AISIN CHEM CO LTD 1981-12-23 JP disclosed
JP-S56167766-A HIGHLY THICK COAT-TYPE PAINT AISIN CHEM CO LTD 1981-12-23 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281171-A1 THERAPEUTIC SUBSTITUTED THIAZOLIDINONES, OXAZOLIDINONES, AND RELATED COMPOUNDS ABAT, ABCB1, TPMT SMN1; SMN2 3707/4885L3MBTL1 3536/4885TSHR 1819/4885
US-20070281981-A1 Glaucoma; 3-substituted pyrrolidine compounds; prostaglandin receptor modulators PTGIR, PTGIS, PTGS1 SMN1; SMN2 4867/4885L3MBTL1 4883/4885TSHR 745/4885
US-20110263692-A1 THERAPEUTIC COMPOUNDS GOT2, ANXA5, MMP8 SMN1; SMN2 1812/4885L3MBTL1 4299/4885TSHR 4382/4885
US-20080051374-A1 Therapeutic Amides and related Compounds GOT2, ACER2, GOT1 SMN1; SMN2 2438/4885L3MBTL1 4556/4885TSHR 2257/4885
US-20090247594-A1 THERAPEUTIC COMPOUNDS ACER2, SLC10A1, ASAH2 SMN1; SMN2 1412/4885L3MBTL1 3886/4885TSHR 3467/4885
US-20090227635-A1 THERAPEUTIC COMPOUNDS SLC10A1, ABCB11, ACER2 SMN1; SMN2 1318/4885L3MBTL1 3590/4885TSHR 3537/4885
US-20090209538-A1 THERAPEUTIC SUBSTITUTED LACTAMS DAO, TUBB2A, TOP1 SMN1; SMN2 1722/4885L3MBTL1 3773/4885TSHR 3998/4885
US-20070259836-A1 THERAPEUTIC CYCLOPENTANE DERIVATIVES PTGIS, PTGIR, CYP11B2 SMN1; SMN2 3307/4885L3MBTL1 4794/4885TSHR 3963/4885
US-20110152255-A1 THERAPEUTIC COMPOUNDS SLC10A2, CYP11B1, CYP11B2 SMN1; SMN2 3127/4885L3MBTL1 4754/4885TSHR 4760/4885
US-20090099249-A1 THERAPEUTIC LACTAMS CLPP, NOTUM, PEPD SMN1; SMN2 3815/4885L3MBTL1 4407/4885TSHR 4505/4885
US-20150274658-A1 THERAPEUTIC LACTAMS CLPP, NOTUM, PEPD SMN1; SMN2 3815/4885L3MBTL1 4407/4885TSHR 4505/4885
US-20090163560-A1 THERAPEUTIC N-ARYL OR N-HETEROARYL PYRAZOLIDINE AND PYRAZOLIDINONE DERIVATIVES GOT2, GOT1, NME4 SMN1; SMN2 2020/4885L3MBTL1 4740/4885TSHR 1819/4885
US-20130231322-A1 THERAPEUTIC SUBSTITUTED BETA-LACTAMS TUBB, GANAB, TUBB6 SMN1; SMN2 2157/4885L3MBTL1 3313/4885TSHR 4344/4885
US-20080027108-A1 THERAPEUTIC SUBSTITUTED LACTAMS SI, GGPS1, B3GAT3 SMN1; SMN2 1607/4885L3MBTL1 3319/4885TSHR 4249/4885
US-20080119539-A1 THERAPEUTIC AMIDES GOT2, GOT1, ARG2 SMN1; SMN2 2131/4885L3MBTL1 4403/4885TSHR 2420/4885
US-20130261130-A1 NEUROTRYPSIN INHIBITORS MTPN, CHRNA7, CHRNA10 SMN1; SMN2 84/4885L3MBTL1 3308/4885TSHR 105/4885
US-20060094708-A1 to treat cellular proliferative diseases, hyperplasias, solid tumor, cardiac hypertrophy, immune disorders and inflammation; modulators of one or more mitotic kinesins; N-(2-(2-dimethylamino-acetylamino)-1-{4-[8-(1-hydroxy-ethyl)-imidazo[1,2-a]pyridin-2-yl]-benzyl}-ethyl)-3-chloro-4-isopropoxy-benzamide KIF5B, KIF18A, KIF2C SMN1; SMN2 2356/4885L3MBTL1 1788/4885TSHR 3315/4885
US-20140323510-A1 SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS ABCB1, THPO, UGT2B7 SMN1; SMN2 2991/4885L3MBTL1 3994/4885TSHR 2567/4885
US-20080039505-A1 THERAPEUTIC LACTAMS CLPP, NOTUM, PEPD SMN1; SMN2 3815/4885L3MBTL1 4407/4885TSHR 4505/4885
US-20090215740-A1 THERAPEUTIC SUBSTITUTED BETA-LACTAMS TUBB, GANAB, TUBB6 SMN1; SMN2 2157/4885L3MBTL1 3313/4885TSHR 4344/4885
US-20070259929-A1 Therapeutic Compounds PIGO, CYC1, COXFA4L2 SMN1; SMN2 1920/4885L3MBTL1 3867/4885TSHR 3918/4885
US-20090281101-A1 THERAPEUTIC SUBSTITUTED HYDANTOINS, AND RELATED COMPOUNDS AADAC, ABCG2, SLC10A1 SMN1; SMN2 3324/4885L3MBTL1 1424/4885TSHR 3201/4885
US-20090227636-A1 THERAPEUTIC COMPOUNDS ACER2, ASAH2, SLC10A1 SMN1; SMN2 1362/4885L3MBTL1 4085/4885TSHR 3559/4885
US-20060247289-A1 Certain chemical entities, compositions, and methods KIF5B, KIF2C, PLK1 SMN1; SMN2 1149/4885L3MBTL1 2781/4885TSHR 4714/4885
US-20090016981-A1 THERAPEUTIC COMPOUNDS GOT2, ANXA5, MMP8 SMN1; SMN2 1812/4885L3MBTL1 4299/4885TSHR 4382/4885
US-20090239858-A1 THERAPEUTIC AMIDES ACER2, SLC10A1, ASAH2 SMN1; SMN2 2274/4885L3MBTL1 2999/4885TSHR 2915/4885
US-20030130349-A1 Inhibitors of alpha 4beta1 mediated cell adhesion VCAM1, ICAM1, ITGB1 SMN1; SMN2 3398/4885L3MBTL1 1105/4885TSHR 4066/4885
US-20080045576-A1 THERAPEUTIC N-ARYL OR N-HETEROARYL PYRAZOLIDINE AND PYRAZOLIDINONE DERIVATIVES GOT2, GOT1, NME4 SMN1; SMN2 2020/4885L3MBTL1 4740/4885TSHR 1819/4885
US-20090306127-A1 Certain Chemical Entities, Compositions and Methods KIF5B, KIF2C, PLK1 SMN1; SMN2 1306/4885L3MBTL1 2793/4885TSHR 4746/4885
US-20100093809-A1 THERAPEUTIC SUBSTITUTED THIAZOLIDINONES, OXAZOLIDINONES, AND RELATED COMPOUNDS THPO, MT-ND4L, ABAT SMN1; SMN2 3813/4885L3MBTL1 4466/4885TSHR 1896/4885
US-20080058397-A1 5-(3-(3-(4-hexanoylphenyl)-2,5-dioxoimidazolidin-4-yl)propyl)thiophene-2-carboxylic acid; prostaglandin agonist; ocular hypotensive agent; post-sergical and post-laser trabeculectomy ocular hypertensive episodes, glaucoma, and as presurgical adjuncts PTGIS, PTGIR, PTGS1 SMN1; SMN2 4882/4885L3MBTL1 4593/4885TSHR 562/4885
US-20090281102-A1 THERAPEUTIC N-ARYL OR N-HETEROARYL PYRAZOLIDINE AND PYRAZOLIDINONE DERIVATIVES GOT1, NAT1, TK1 SMN1; SMN2 1190/4885L3MBTL1 3463/4885TSHR 3063/4885
US-20090281104-A1 Therapeutic Compounds SLC10A1, ABCB11, GUSB SMN1; SMN2 1306/4885L3MBTL1 3358/4885TSHR 3776/4885
US-20080255182-A1 Certain chemical entities, compositions, and methods KIF5B, KIF2C, PLK1 SMN1; SMN2 1149/4885L3MBTL1 2781/4885TSHR 4714/4885
US-20070259947-A1 THERAPEUTIC COMPOUNDS GOT2, ANXA5, MMP8 SMN1; SMN2 1812/4885L3MBTL1 4299/4885TSHR 4382/4885
US-20080058387-A1 5-(3-(3-(4-(1-hydroxyhexyl)phenyl)-4-oxo-thiazolidin-2-yl)propyl)thiophene-2-carboxylic acid; prostaglandin agonist; ocular hypotensive agents; post-surgical and post-laser trabeculectomy ocular hypertensive episodes, glaucoma, and as presurgical adjuncts PTGIS, PTGIR, PTGS1 SMN1; SMN2 4884/4885L3MBTL1 4531/4885TSHR 387/4885
US-20070265321-A1 THERAPEUTIC COMPOUNDS ACER2, SLC10A1, ASAH2 SMN1; SMN2 1412/4885L3MBTL1 3886/4885TSHR 3467/4885
US-20090286841-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS KIF5B, KIF2C, PLK1 SMN1; SMN2 1149/4885L3MBTL1 2781/4885TSHR 4714/4885
US-20080033023-A1 Treating eye diseases including glaucoma or ocular hypertension; selective prostaglandin EP2 agonists; acid-functional aryl substituted pyrrolidine compounds PTGER2, PTGS2, PTGIS SMN1; SMN2 4750/4885L3MBTL1 4868/4885TSHR 1927/4885
US-20170057941-A1 SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS ABCB1, THPO, UGT2B7 SMN1; SMN2 2991/4885L3MBTL1 3994/4885TSHR 2567/4885
US-20120283287-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS KIF5B, KIF2C, PLK1 SMN1; SMN2 1149/4885L3MBTL1 2781/4885TSHR 4714/4885
US-20090270387-A1 SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS ABCB1, UGT2B7, GBA1 SMN1; SMN2 2680/4885L3MBTL1 3055/4885TSHR 2289/4885
US-20070270387-A1 THERAPEUTIC CYCLOPENTANE DERIVATIVES ABCB1, CYP11B2, SLC10A1 SMN1; SMN2 2885/4885L3MBTL1 4690/4885TSHR 3551/4885
US-20090233931-A1 THERAPEUTIC COMPOUNDS SLC10A1, ABCB11, ACER2 SMN1; SMN2 1268/4885L3MBTL1 2816/4885TSHR 4242/4885
US-20090233921-A1 THERAPEUTIC CYCLOPENTANE DERIVATIVES PDE3A, CYP11B2, PDE7A SMN1; SMN2 2718/4885L3MBTL1 4576/4885TSHR 3585/4885
US-20090192151-A1 THERAPEUTIC AMIDES AND RELATED COMPOUNDS VIP, SHH, GLI1 SMN1; SMN2 4385/4885L3MBTL1 4695/4885TSHR 1481/4885
US-20090312365-A1 Certain Chemical Entities, Compositions, and Methods KIF5B, KIF2C, PLK1 SMN1; SMN2 1149/4885L3MBTL1 2781/4885TSHR 4714/4885
US-20100168189-A1 THERAPEUTIC SUBSTITUTED LACTAMS PIGO, GARS1, CLPP SMN1; SMN2 3289/4885L3MBTL1 3603/4885TSHR 4545/4885
US-20090318449-A1 THERAPEUTIC LACTAMS ABCB11, TOP1, SLC10A2 SMN1; SMN2 1173/4885L3MBTL1 3299/4885TSHR 4739/4885
US-20100137347-A1 SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS ABCB1, THPO, UGT2B7 SMN1; SMN2 2177/4885L3MBTL1 4172/4885TSHR 2868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.