Hydrochloric Acid

Hydrochloric Acid

SCHEMBL94101

CCCCCCCCCCCCCCCCCCC(C)(O)N(C)C.Cl

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FDPS P14324 9/20 0.42
GGPS1 O95749 7/20 0.42
DNM1 Q05193 2/20 0.41
SMPD1 P17405 1/20 0.38
CES2 O00748 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28643343 1.00 FDPS (0.42) FDPSGGPS1DNM1SMPD1CES2
SCHEMBL20137187 0.98 FDPS (0.43) FDPSGGPS1DNM1SMPD1
SCHEMBL20137246 0.98 FDPS (0.43) FDPSGGPS1DNM1SMPD1
Bromide SCHEMBL28426210 0.95 FDPS (0.42) FDPSGGPS1DNM1SMPD1CES2
Water SCHEMBL11076441 0.95 FDPS (0.42) FDPSGGPS1DNM1SMPD1CES2
Hydrochloric Acid SCHEMBL11125698 0.91 FDPS (0.33) FDPSGGPS1DNM1
Phosphoric Acid SCHEMBL7141094 0.88 FDPS (0.55) FDPSGGPS1SMPD1
Nitric Acid SCHEMBL27976858 0.85 ALDH1A1 (0.39) FDPSGGPS1SMPD1CES2
Hydrochloric Acid SCHEMBL23413051 0.83 DNM1 (0.46) FDPSGGPS1DNM1
Hydrochloric Acid SCHEMBL4607606 0.83 DNM1 (0.46) FDPSGGPS1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220175657-A1 METHOD FOR TREATING HAIR AND SCALP KAO GERMANY GMBH (DE) 2022-06-09 US disclosed
EP-3930662-A1 METHOD FOR TREATING HAIR AND SCALP Kao Germany GmbH (DE) 2022-01-05 EP disclosed
EP-2560606-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2017-08-23 EP disclosed
EP-2611411-B1 AQUEOUS COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2017-06-28 EP disclosed
EP-2560608-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2017-04-05 EP disclosed
EP-2346481-B1 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2016-08-31 EP disclosed
EP-2424620-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2016-06-08 EP disclosed
EP-2377513-B1 Colouring composition KAO GERMANY GMBH (DE) 2016-03-30 EP disclosed
EP-2346480-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2016-01-06 EP disclosed
US-8795391-B2 Colouring composition KAO GERMANY GMBH (DE) 2014-08-05 US disclosed
US-7638506-B2 cationic surfactants; wear resistance; kneading, extrusion; sustained release KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2009-12-29 US disclosed
US-20070105720-A1 Granular agrochemical composition OZAKI EISUKE 2007-05-10 US disclosed
CN-1307873-C Granular agricultural-chemical composition KUMIAI CHEMICAL INDUSTRY CO (JP) 2007-04-04 CN disclosed
US-20060287199-A1 Time-release agent comprising an aqueous solution of both nondisintegrating acid pesticide granules and a water soluble pesticide; a cationic surfactant and base; sulfonylureas and difluoromethanesulfonylanilide dissolve after 30 minutes; environmentally friendly; nonphytotoxic; simplification KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2006-12-21 US disclosed
US-20050250648-A1 Granular agricultura-chemical composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-11-10 US disclosed
CN-1642416-A Granular pesticide composition KUMIAI CHEMICAL INDUSTRY CO (JP) 2005-07-20 CN disclosed
US-6903035-B2 Inorganic composition, film, and method of producing film FUJI PHOTO FILM CO., LTD. (JP) 2005-06-07 US disclosed
EP-1498030-A1 GRANULAR AGRICULTURAL-CHEMICAL COMPOSITION KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-01-19 EP disclosed
US-20030116061-A1 Inorganic composition, film, and method of producing film FUJI PHOTO FILM CO., LTD. 2003-06-26 US disclosed
EP-1281689-A2 Inorganic composition, film made therefrom, and method for producing such film FUJI PHOTO FILM CO., LTD. (JP) 2003-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050250648-A1 Granular agricultura-chemical composition PRKG1, PRKAG2, AGK FDPS 4212/4885GGPS1 847/4885DNM1 1032/4885
US-20060287199-A1 Time-release agent comprising an aqueous solution of both nondisintegrating acid pesticide granules and a water soluble pesticide; a cationic surfactant and base; sulfonylureas and difluoromethanesulfonylanilide dissolve after 30 minutes; environmentally friendly; nonphytotoxic; simplification GCG, CASP12, CTRL FDPS 3006/4885GGPS1 2787/4885DNM1 426/4885
US-20220175657-A1 METHOD FOR TREATING HAIR AND SCALP POLR1C, ALPG, SUCLG1 FDPS 4494/4885GGPS1 4585/4885DNM1 3591/4885
US-20070105720-A1 Granular agrochemical composition AGL, PLA2G2C, GYPA FDPS 4600/4885GGPS1 542/4885DNM1 1679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.