Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 3/20 | 0.65 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.41 |
| ▸ | DRD2 known ✓ | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 known ✓ | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 known ✓ | P21917 | 1/20 | 0.41 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.41 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.41 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31134106 | 1.00 | KDM4E (0.65) | KDM4EGAAMAPTPOLBMEN1 | |
| SCHEMBL29631753 | 0.98 | POLB (0.68) | KDM4EGAAMAPTPOLBMEN1 | |
| SCHEMBL454989 | 0.98 | POLB (0.68) | KDM4EGAAMAPTPOLBMEN1 | |
| SCHEMBL14645890 | 0.88 | RAB9A (0.57) | KDM4EGAAMAPTPOLBMEN1 | |
| Phosphoric Acid SCHEMBL5176868 | 0.88 | GAA (0.57) | KDM4EGAAMAPTPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL11091223 | 0.83 | TRPA1 (0.61) | KDM4EGAAMAPTPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL21173968 | 0.82 | MAPT (0.95) | KDM4EGAAMAPTPOLBMEN1 | |
| SCHEMBL2786932 | 0.81 | KDM4E (0.63) | KDM4EGAAMAPTPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL3574208 | 0.80 | MAPT (0.68) | KDM4EGAAMAPTPOLBMEN1 | |
| SCHEMBL1025691 | 0.80 | TRPA1 (0.64) | KDM4EGAAMAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084688-A | Preparation method of 2-hydroxy-4-ethylaniline and hydrochloride thereof | 浙江鼎龙科技股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-118063332-A | Preparation method of 2-hydroxy-4-ethylaniline and hydrochloride thereof | 浙江鼎龙科技股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-118063333-A | Preparation method of 2-hydroxy-4-ethylaniline and hydrochloride thereof | 浙江鼎龙科技股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| US-20260137607-A1 | COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND A FATTY ACID ESTER OF GLYCEROL | LOREAL (FR) | 2026-05-21 | — | — | US | disclosed |
| EP-4262720-B1 | COMPOSITION COMPRISING TWO PARTICULAR OXIDATION DYE PRECURSORS, AND A PARTICULAR CARBOXYLIC ACID | OREAL (FR) | 2026-05-06 | — | — | EP | disclosed |
| EP-4262716-B1 | COMPOSITION COMPRISING A PARTICULAR OXIDATION DYE PRECURSOR AND A PARTICULAR CARBOXYLIC ACID | OREAL (FR) | 2026-05-06 | — | — | EP | disclosed |
| US-12589063-B2 | Composition comprising a combination of two particular oxidation dye precursors, an amphoteric or zwitterionic surfactant and a solid fatty substance | L'OREAL (FR) | 2026-03-31 | — | — | US | disclosed |
| US-12583876-B2 | Branched organosilicon compound, method of preparing same, and related compositions | DOW SILICONES CORPORATION (US) | 2026-03-24 | — | — | US | disclosed |
| US-12569420-B2 | Composition comprising a particular oxidation dyeing base and at least two particular couplers | L'ORÉAL (FR) | 2026-03-10 | — | — | US | disclosed |
| EP-4422582-B1 | COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND A FATTY ACID ESTER OF GLYCEROL | OREAL (FR) | 2025-11-05 | — | — | EP | disclosed |
| EP-3493878-B1 | COSMETIC COMPOSITION COMPRISING CURED SILICONE MATERIALS | DOW SILICONES CORP (US) | 2025-10-08 | — | — | EP | disclosed |
| US-20160184214-A1 | COSMETIC COMPOSITIONS CONTAINING SILICONES | DOW CORNING CORPORATION (US) | 2016-06-30 | — | — | US | disclosed |
| US-20150322097-A1 | PROCESS FOR PREPARING AN ORGANOSILANE COMPOSITION | DOW SILICONES CORPORATION | 2015-11-12 | — | — | US | disclosed |
| CN-104769092-A | Fabric care compositions comprising emulsions | DOW CORNING | 2015-07-08 | — | — | CN | disclosed |
| US-20140127140-A1 | Cosmetic Composition Comprising Hydrophilic Organosilanes | DOW CORNING CORPORATION (US) | 2014-05-08 | — | — | US | disclosed |
| CN-103491937-A | Oxidative dyeing composition comprising 1-hexyl/heptyl-4, 5-diaminopyrazole and 2-aminophenol and derivatives thereof | PROCTER & GAMBLE | 2014-01-01 | — | — | CN | disclosed |
| US-20130336909-A1 | PERSONAL CARE AND HEALTH CARE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2013-12-19 | — | — | US | disclosed |
| US-8444709-B2 | Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-diaminopyrazole and a 2-aminophenol and derivatives thereof | THE PROCTER & GAMBLE COMPANY (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120210519-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a 2-Aminophenol and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | disclosed |
| US-5214194-A | Preparation of 5-substituted 2-aminophenols, reaction of nitrone with trichloroacetyl chloride | EASTMAN KODAK COMPANY (US) | 1993-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12589063-B2 | Composition comprising a combination of two particular oxidation dye precursors, an amphoteric or zwitterionic surfactant and a solid fatty substance | S100P, KRT18, S100A4 | GAA 4691/4885ADRA2A 2791/4885DRD2 2634/4885 |
| US-20120210519-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a 2-Aminophenol and Derivatives Thereof | TYR, GPX4, TH | GAA 4087/4885ADRA2A 1674/4885DRD2 770/4885 |
| US-12569420-B2 | Composition comprising a particular oxidation dyeing base and at least two particular couplers | KRT18, COL1A1, S100P | GAA 4826/4885ADRA2A 2116/4885DRD2 1154/4885 |
| US-20260137607-A1 | COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND A FATTY ACID ESTER OF GLYCEROL | KRT18, FABP4, HSD17B4 | GAA 3169/4885ADRA2A 355/4885DRD2 870/4885 |
| US-12583876-B2 | Branched organosilicon compound, method of preparing same, and related compositions | OXSR1, BRS3, NPSR1 | GAA 4501/4885ADRA2A 817/4885DRD2 1021/4885 |
| US-20150322097-A1 | PROCESS FOR PREPARING AN ORGANOSILANE COMPOSITION | BRS3, HRH3, H1-3 | GAA 4628/4885ADRA2A 1640/4885DRD2 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.