Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25408511 | 1.00 | DNM1 (0.46) | DNM1GBA1PLA2G1BPLA2G2AGGPS1 | |
| Hydrochloric Acid SCHEMBL4893519 | 1.00 | DNM1 (0.46) | DNM1GBA1PLA2G1BPLA2G2AGGPS1 | |
| Hydrochloric Acid SCHEMBL1775319 | 1.00 | DNM1 (0.46) | DNM1GBA1PLA2G1BPLA2G2AGGPS1 | |
| Hydrochloric Acid SCHEMBL5604439 | 1.00 | DNM1 (0.46) | DNM1GBA1PLA2G1BPLA2G2AGGPS1 | |
| Hydrochloric Acid SCHEMBL8461416 | 1.00 | DNM1 (0.46) | DNM1GBA1PLA2G1BPLA2G2AGGPS1 | |
| SCHEMBL4448024 | 0.98 | DNM1 (0.44) | DNM1GBA1PLA2G1BPLA2G2AGGPS1 | |
| SCHEMBL10456043 | 0.98 | DNM1 (0.44) | DNM1GBA1PLA2G1BPLA2G2AGGPS1 | |
| SCHEMBL10619708 | 0.98 | DNM1 (0.44) | DNM1GBA1PLA2G1BPLA2G2AGGPS1 | |
| Bromide SCHEMBL28604930 | 0.95 | DNM1 (0.46) | DNM1GBA1PLA2G1BPLA2G2AGGPS1 | |
| SCHEMBL29174043 | 0.93 | DNM1 (0.41) | DNM1GBA1PLA2G1BPLA2G2AGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12605325-B2 | Hair styling compositions for improving the elongation of hair curls | L'OREAL (FR) | 2026-04-21 | — | — | US | disclosed |
| US-12599546-B2 | Hair treatment compositions, kits thereof, and methods thereof | L'OREAL (FR) | 2026-04-14 | — | — | US | disclosed |
| US-12589065-B2 | Hair care system, hair care method and use of a hair care system | L'OREAL (FR) | 2026-03-31 | — | — | US | disclosed |
| US-12551422-B2 | Compositions and methods for styling the hair | L'ORÉAL (FR) | 2026-02-17 | — | — | US | disclosed |
| EP-4633589-A1 | HAIR TREATMENT COMPOSITIONS THAT IMPART SHINE AND LUSTER | L'OREAL (FR) | 2025-10-22 | — | — | EP | disclosed |
| US-12383483-B2 | Compositions and methods for styling the hair | L'OREAL (FR) | 2025-08-12 | — | — | US | disclosed |
| US-12290589-B2 | Cosmetic and personal care compositions containing cationic surfactants and anionic compounds | L'OREAL (FR) | 2025-05-06 | — | — | US | disclosed |
| US-20250127697-A1 | HAIR TREATMENT COMPOSITION WITH CATIONIC SURFACTANT, FATTY ALCOHOLS, AND LOW POLAR OIL | L'OREAL (FR) | 2025-04-24 | — | — | US | disclosed |
| WO-2025085270-A1 | HAIR TREATMENT COMPOSITION WITH CATIONIC SURFACTANT, FATTY ALCOHOLS, AND LOW POLAR OIL | L'OREAL (FR) | 2025-04-24 | — | — | WO | disclosed |
| US-12268767-B2 | Compositions and methods for treating hair | L'OREAL (FR) | 2025-04-08 | — | — | US | disclosed |
| WO-2010060602-A1 | PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-06-03 | — | — | WO | disclosed |
| WO-2010060601-A1 | BLEACHING/HIGHLIGHTING COMPOSITION | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-06-03 | — | — | WO | disclosed |
| EP-2191863-A1 | Composition for the permanent shaping of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-06-02 | — | — | EP | disclosed |
| EP-2191812-A1 | Bleaching/Highlighting composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-06-02 | — | — | EP | disclosed |
| WO-2010046077-A2 | COLOURING COMPOSITION | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046080-A2 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |
| EP-2177204-A1 | Colouring composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
| EP-2177205-A1 | Composition for the permanent shaping of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
| WO-2010025894-A2 | CONDITIONING COMPOSITION FOR HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |
| EP-2161016-A1 | Conditioning composition for hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12605325-B2 | Hair styling compositions for improving the elongation of hair curls | SGMS1, SGMS2, SGPL1 | CA2 1860/4885DNM1 1754/4885GBA1 743/4885 |
| US-12551422-B2 | Compositions and methods for styling the hair | DPM1, PIK3C3, SMURF1 | CA2 2001/4885DNM1 3148/4885GBA1 2692/4885 |
| US-12589065-B2 | Hair care system, hair care method and use of a hair care system | ASH2L, ALG3, PLOD3 | CA2 3333/4885DNM1 2868/4885GBA1 4004/4885 |
| US-12599546-B2 | Hair treatment compositions, kits thereof, and methods thereof | EBP, FHIT, BRDT | CA2 2503/4885DNM1 2400/4885GBA1 3704/4885 |
| US-20250127697-A1 | HAIR TREATMENT COMPOSITION WITH CATIONIC SURFACTANT, FATTY ALCOHOLS, AND LOW POLAR OIL | SGMS1, SGMS2, POLR1C | CA2 3611/4885DNM1 65/4885GBA1 3487/4885 |
| US-12290589-B2 | Cosmetic and personal care compositions containing cationic surfactants and anionic compounds | CUTA, SGMS1, PHOSPHO1 | CA2 1584/4885DNM1 2110/4885GBA1 793/4885 |
| US-12383483-B2 | Compositions and methods for styling the hair | SGMS1, SGMS2, DPM1 | CA2 3195/4885DNM1 3457/4885GBA1 1312/4885 |
| US-12268767-B2 | Compositions and methods for treating hair | UNG, OAT, OTC | CA2 330/4885DNM1 4103/4885GBA1 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.