Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14844376 | 1.00 | FAP (0.30) | FAP | |
| SCHEMBL2010924 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL14845240 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL14845242 | 0.76 | — | — | |
| SCHEMBL23977293 | 0.75 | — | — | |
| SCHEMBL19198264 | 0.75 | — | — | |
| SCHEMBL4760427 | 0.74 | FAP (0.33) | FAP | |
| SCHEMBL2034225 | 0.74 | FAP (0.33) | FAP | |
| SCHEMBL2034229 | 0.74 | FAP (0.33) | FAP | |
| SCHEMBL2688336 | 0.74 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595239-B2 | Substituted isoxazoline derivatives | BASF SE (DE) | 2026-04-07 | — | — | US | disclosed |
| US-20260015325-A1 | ALKOXY HETEROARYL- CARBOXAMIDE OR THIOAMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2026-01-15 | — | — | US | disclosed |
| EP-4291551-B1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | BASF SE (DE) | 2025-08-13 | — | — | EP | disclosed |
| EP-4522592-A1 | ALKOXY HETEROARYL- CARBOXAMIDE OR THIOAMIDE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-03-19 | — | — | EP | disclosed |
| US-12137688-B2 | Naphthalene isoxazoline compounds for controlling invertebrate pests | FMC CORPORATION (US) | 2024-11-12 | — | — | US | disclosed |
| US-20240140917-A1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | BASF SE (DE) | 2024-05-02 | — | — | US | disclosed |
| EP-4291551-A1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | BASF SE (DE) | 2023-12-20 | — | — | EP | disclosed |
| WO-2023217989-A1 | ALKOXY HETEROARYL- CARBOXAMIDE OR THIOAMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-11-16 | — | — | WO | disclosed |
| US-20230157293-A1 | NAPHTHALENE ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC CORPORATION | 2023-05-25 | — | — | US | disclosed |
| US-11576382-B2 | Naphthalene isoxazoline compounds for controlling invertebrate pests | FMC CORPORATION (US) | 2023-02-14 | — | — | US | disclosed |
| WO-2019156903-A1 | NAPHTHALENE ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC CORPORATION (US) | 2019-08-15 | — | — | WO | disclosed |
| US-9815803-B2 | Process for the preparation of substituted cycloserines | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-14 | — | — | US | disclosed |
| US-20170204072-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYCLOSERINES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-20 | — | — | US | disclosed |
| US-9643938-B2 | Process for the preparation of substituted cycloserines | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-09 | — | — | US | disclosed |
| EP-3137449-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYCLOSERINES | Syngenta Participations AG (CH) | 2017-03-08 | — | — | EP | disclosed |
| US-20170044116-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYCLOSERINES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-16 | — | — | US | disclosed |
| WO-2015166094-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYCLOSERINES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-11-05 | — | — | WO | disclosed |
| US-20140243375-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-28 | — | — | US | disclosed |
| EP-2763970-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050302-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595239-B2 | Substituted isoxazoline derivatives | CBR3, ADRA2C, CYP4Z1 | FAP 4810/4885 |
| US-20170044116-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYCLOSERINES | C1S, C1R, C5 | FAP 1883/4885 |
| US-20230157293-A1 | NAPHTHALENE ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | RDX, RPS4X, CYP4X1 | FAP 4822/4885 |
| US-20240140917-A1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | CYP4X1, PRDX5, PRDX1 | FAP 4622/4885 |
| US-20140243375-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | CBR3, CYCS, NOX3 | FAP 4706/4885 |
| US-20260015325-A1 | ALKOXY HETEROARYL- CARBOXAMIDE OR THIOAMIDE COMPOUNDS | CYCS, CBR3, CBR1 | FAP 4194/4885 |
| US-20170204072-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYCLOSERINES | C1S, C1R, C5 | FAP 2055/4885 |
| US-11576382-B2 | Naphthalene isoxazoline compounds for controlling invertebrate pests | RDX, RPS4X, CYP4X1 | FAP 4822/4885 |
| US-12137688-B2 | Naphthalene isoxazoline compounds for controlling invertebrate pests | RDX, RPS4X, CYP4X1 | FAP 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.