Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 known ✓ | P11926 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26526 | 0.98 | TSHR (0.62) | TSHRTHRBTDP1POLBAPEX1 | |
| Ammonia Solution, Strong SCHEMBL27449301 | 0.96 | TSHR (0.60) | TSHRTHRBTDP1POLBAPEX1 | |
| Bromide SCHEMBL27996969 | 0.96 | TSHR (0.60) | TSHRTHRBTDP1POLBAPEX1 | |
| Trimethylammonium SCHEMBL23854269 | 0.94 | TSHR (0.55) | TSHRTHRBTDP1POLBAPEX1 | |
| Trimethylammonium SCHEMBL27603493 | 0.94 | TSHR (0.55) | TSHRTHRBTDP1POLBAPEX1 | |
| Dimethylamine SCHEMBL28338227 | 0.92 | TSHR (0.56) | TSHRTHRBTDP1POLBAPEX1 | |
| Trimethylammonium SCHEMBL29027511 | 0.92 | TSHR (0.56) | TSHRTHRBTDP1POLBAPEX1 | |
| Hydrochloric Acid SCHEMBL11438451 | 0.92 | TSHR (0.67) | TSHRTHRBTDP1POLBAPEX1 | |
| Hydrochloric Acid SCHEMBL1436530 | 0.92 | TSHR (0.67) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL344935 | 0.92 | TSHR (0.66) | TSHRTHRBTDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713720-A2 | HIGH-ENERGY-VIOLET-ABSORBING VINYLIC MONOMERS | Alcon Inc. (CH) | 2026-03-25 | — | — | EP | claimed |
| US-20260042269-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2026-02-12 | — | — | US | claimed |
| US-20260042268-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2026-02-12 | — | — | US | claimed |
| US-20250387989-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2025-12-25 | — | — | US | claimed |
| EP-4657145-A2 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | Alcon Inc. (CH) | 2025-12-03 | — | — | EP | claimed |
| EP-4657144-A2 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | Alcon Inc. (CH) | 2025-12-03 | — | — | EP | claimed |
| US-12420501-B2 | Silicone hydrogel lenses with water-rich surfaces | ALCON INC. (CH) | 2025-09-23 | — | — | US | claimed |
| WO-2024236526-A2 | HIGH-ENERGY-VIOLET-ABSORBING VINYLIC MONOMERS | ALCON INC. (CH) | 2024-11-21 | — | — | WO | claimed |
| US-20240383865-A1 | HIGH-ENERGY-VIOLET-ABSORBING VINYLIC MONOMERS | ALCON INC (CH) | 2024-11-21 | — | — | US | claimed |
| EP-4431564-A1 | CONTACT LENS AND MANUFACTURING METHOD THEREFOR | Pegavision Corporation (TW) | 2024-09-18 | — | — | EP | claimed |
| WO-2010135481-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | NOVARTIS AG (CH) | 2010-11-25 | — | — | WO | claimed |
| WO-2010133680-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | NOVARTIS AG (CH) | 2010-11-25 | — | — | WO | claimed |
| US-20100296049-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ALCON INC. (CH) | 2010-11-25 | — | — | US | claimed |
| JP-2010522265-A | — | — | 2010-07-01 | — | — | JP | claimed |
| WO-2010056687-A2 | SILICONE HYDROGEL MATERIALS WITH CHEMICALLY BOUND WETTING AGENTS | NOVARTIS AG (CH) | 2010-05-20 | — | — | WO | claimed |
| US-20100120939-A1 | SILICONE HYDROGEL MATERIALS WITH CHEMICALLY BOUND WETTING AGENTS | ALCON INC. (CH) | 2010-05-13 | — | — | US | claimed |
| CN-101641206-A | Prepolymers having polymer chains containing dangling polysiloxanes | NOVARTIS AG CH | 2010-02-03 | — | — | CN | claimed |
| EP-2129513-A2 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | Novartis Ag (CH) | 2009-12-09 | — | — | EP | claimed |
| WO-2008116131-A2 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | NOVARTIS AG (CH) | 2008-09-25 | — | — | WO | claimed |
| US-20080231798-A1 | Prepolymers with dangling polysiloxane-containing polymer chains | ALCON INC. (CH) | 2008-09-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042269-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | CRYZ, STRA6, PHOSPHO1 | ODC1 228/4885TSHR 2055/4885THRB 2097/4885 |
| US-20100120939-A1 | SILICONE HYDROGEL MATERIALS WITH CHEMICALLY BOUND WETTING AGENTS | CRYAA, CRYAB, PCNA | ODC1 1008/4885TSHR 3793/4885THRB 3251/4885 |
| US-20100296049-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | VCL, MACF1, CFL1 | ODC1 2754/4885TSHR 3589/4885THRB 4456/4885 |
| US-20240383865-A1 | HIGH-ENERGY-VIOLET-ABSORBING VINYLIC MONOMERS | VCL, HBS1L, SAAL1 | ODC1 3619/4885TSHR 2984/4885THRB 1222/4885 |
| US-20260042268-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | STRA6, CRYZ, SMCHD1 | ODC1 419/4885TSHR 1985/4885THRB 2866/4885 |
| US-20250387989-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | PHOSPHO1, MYOC, ASS1 | ODC1 741/4885TSHR 1508/4885THRB 1271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.