Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110723 | 0.78 | MAPK1 (0.36) | KIF11MAPK1KCNN4TSHRALDH1A1 | |
| SCHEMBL905247 | 0.76 | KCNN4 (0.38) | MAPK1KCNN4TSHRALDH1A1KMT2A | |
| SCHEMBL131978 | 0.76 | MAPK1 (0.44) | MAPK1KCNN4TSHRALDH1A1KMT2A | |
| SCHEMBL519210 | 0.76 | KCNN4 (0.38) | MAPK1KCNN4TSHRALDH1A1KMT2A | |
| SCHEMBL135667 | 0.76 | MAPK1 (0.56) | MAPK1KCNN4TSHRALDH1A1KMT2A | |
| SCHEMBL1683185 | 0.76 | TSHR (0.44) | MAPK1KCNN4TSHRALDH1A1KMT2A | |
| SCHEMBL6048821 | 0.75 | KIF11 (0.40) | KIF11MAPK1KCNN4TSHRALDH1A1 | |
| SCHEMBL7636187 | 0.75 | TSHR (0.42) | KIF11MAPK1KCNN4TSHRALDH1A1 | |
| SCHEMBL6394434 | 0.73 | MAPK1 (0.41) | MAPK1KCNN4TSHRALDH1A1KMT2A | |
| SCHEMBL9210109 | 0.73 | CYP2C19 (0.44) | MAPK1KCNN4TSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 661 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650827-B | Preparation method, intermediate compound and synthesis method for anthracycline derivatives | 戊言医药科技（上海）有限公司 | 2024-03-15 | — | — | CN | claimed |
| JP-2007501805-A | — | — | 2007-02-01 | — | — | JP | claimed |
| EP-1651638-A1 | PYRIDYL PIPERAZINYL UREAS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-03 | — | — | EP | claimed |
| US-6888001-B2 | Selective modulators of the nicotinic acetylcholine receptor useful in the treatment of pain, Alzheimer's disease, memory loss or dementia or loss of motor function. | LEE JUNG S (US) | 2005-05-03 | — | — | US | claimed |
| US-20050049241-A1 | Pyridyl piperazinyl ureas | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-03 | — | — | US | claimed |
| WO-2005014580-A1 | PYRIDYL PIPERAZINYL UREAS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-02-17 | — | — | WO | claimed |
| EP-1107965-B1 | PYRIDYL ETHERS AND THIOETHERS AS LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTOR AND ITS THERAPEUTIC APPLICATION | ORTHO MCNEIL PHARM INC (US) | 2004-08-11 | — | — | EP | claimed |
| EP-0990646-B1 | PROCESS FOR PREPARING 3-(7-AMIDINO-2-NAPHTHYL)-2-PHENYLPROPIONIC ACID DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2004-04-28 | — | — | EP | claimed |
| US-20030207858-A1 | Selective modulators of the nicotinic acetylcholine receptor useful in the treatment of pain, Alzheimer's disease, memory loss or dementia or loss of motor function. | LEE JUNG S (US) | 2003-11-06 | — | — | US | claimed |
| US-6562847-B1 | Useful in the treatment of pain, Alzheimer's disease, memory loss or dementia or loss of motor function | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-05-13 | — | — | US | claimed |
| EP-1107965-A1 | PYRIDYL ETHERS AND THIOETHERS AS LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTOR AND ITS THERAPEUTIC APPLICATION | Ortho-McNeil Pharmaceutical, Inc. (US) | 2001-06-20 | — | — | EP | claimed |
| WO-2000010997-A1 | PYRIDYL ETHERS AND THIOETHERS AS LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTOR AND ITS THERAPEUTIC APPLICATION | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-03-02 | — | — | WO | claimed |
| US-5623078-A | Process for producing an intermediate of a new quinolone compound | CHISSO CORPORATION (JP) | 1997-04-22 | — | — | US | claimed |
| US-5234930-A | Treating psychological, cardiovascular, urogenital and respiratory disorders; diabetes, asthmas, sudden infant death syndrome | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | claimed |
| EP-0235796-A2 | Dibenz [b,e] oxepin derivative and antiallergic and antiinflammatory agent | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1987-09-09 | — | — | EP | claimed |
| EP-0056992-A1 | Phosphorylated derivatives, pharmaceutical compositions containing such derivatives, and their use | CIBA-GEIGY AG (CH) | 1982-08-04 | — | — | EP | claimed |
| US-4246405-A | Method for preparation of β-lactam compound | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1981-01-20 | — | — | US | claimed |
| US-4185014-A | Kentenimine intermediates for 6α-methoxy-α-carboxy penicillins | BEECHAM GROUP LIMITED (GB) | 1980-01-22 | — | — | US | claimed |
| US-4180571-A | Arylmalonamido-1-oxadethiacephalosporins | SHIONOGI & CO., LTD. (JP) | 1979-12-25 | — | — | US | claimed |
| JP-9012546-A | — | — | None | — | — | JP | disclosed |
| JP-60215688-A | — | — | None | — | — | JP | disclosed |
| EP-4328234-A1 | COMPOUND FOR ALCOHOLIC LIVER INJURY, PREPARATION METHOD, COMPOSITION, FOOD AND USE | Chengdu Innoheporem Biotech Co., Ltd. (CN) | 2024-02-28 | — | — | EP | disclosed |
| CN-115212288-A | Compound for alcoholic liver injury, preparation method, composition, food and drink and application | 成都因诺生物医药科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-115093408-A | Benzylamine-containing 5, 6-heteroaromatic compounds useful against mycobacterial infections | 盐野义制药株式会社 | 2022-09-23 | — | — | CN | disclosed |
| EP-3412663-B1 | NITROGEN-CONTAINING HETEROCYCLE AND CARBOCYCLE DERIVATIVES HAVING TRKA INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2022-09-07 | — | — | EP | disclosed |
| US-20220235047-A1 | A MEDICAMENT FOR TREATING MYCOBACTERIAL INFECTION CHARACTERIZED BY COMBINING A CYTOCHROME bc1 INHIBITOR WITH CLARITHROMYCIN OR AZITHROMYCIN AND CLOFAZIMINE | SHIONOGI & CO., LTD. (JP) | 2022-07-28 | — | — | US | disclosed |
| EP-4028130-A1 | BENZYL AMINE-CONTAINING 5,6-HETEROAROMATIC COMPOUNDS USEFUL AGAINST MYCOBACTERIAL INFECTION | Shionogi & Co., Ltd (JP) | 2022-07-20 | — | — | EP | disclosed |
| WO-2022119899-A1 | A MEDICAMENT FOR TREATING MYCOBACTERIAL INFECTION CHARACTERIZED BY COMBINING A CYTOCHROME BC1 INHIBITOR WITH CLARITHROMYCIN OR AZITHROMYCIN | SHIONOGI & CO., LTD. (JP) | 2022-06-09 | — | — | WO | disclosed |
| CN-114480035-A | Detergent composition and use thereof | 诺维信公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114401965-A | Benzylamine-containing 5, 6-heteroaromatic compounds useful against mycobacterial infections | 盐野义制药株式会社 | 2022-04-26 | — | — | CN | disclosed |
| EP-3976031-A1 | A MEDICAMENT FOR TREATING MYCOBACTERIAL INFECTION CHARACTERIZED BY COMBINING A CYTOCHROME BC1 INHIBITOR WITH CLARITHROMYCIN OR AZITHROMYCIN AND CLOFAZIMINE | Shionogi & Co., Ltd (JP) | 2022-04-06 | — | — | EP | disclosed |
| CN-109312270-B | Detergent composition and use thereof | 诺维信公司 | 2022-01-28 | — | — | CN | disclosed |
| US-20210348081-A1 | METHOD FOR RELEASING ALDEHYDE OR KETONE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2021-11-11 | — | — | US | disclosed |
| CN-107428700-B | 9-membered fused ring derivative | 盐野义制药株式会社 | 2021-08-03 | — | — | CN | disclosed |
| EP-3330256-B1 | HETEROCYCLIC DERIVATIVE HAVING TrkA-INHIBITING ACTIVITY | SHIONOGI & CO (JP) | 2021-06-16 | — | — | EP | disclosed |
| US-11008320-B2 | Nitrogen-containing heterocycle and carbocycle derivatives having TrkA inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2021-05-18 | — | — | US | disclosed |
| WO-2021050708-A1 | BENZYL AMINE-CONTAINING 5,6-HETEROAROMATIC COMPOUNDS USEFUL AGAINST MYCOBACTERIAL INFECTION | SHIONOGI & CO., LTD. (JP) | 2021-03-18 | — | — | WO | disclosed |
| US-10870661-B2 | Nitrogen-containing tricyclic derivatives having HIV replication inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2020-12-22 | — | — | US | disclosed |
| CN-108495921-B | Detergent composition and use thereof | 诺维信公司 | 2020-12-15 | — | — | CN | disclosed |
| EP-2772480-B2 | HIV REPLICATION INHIBITOR | SHIONOGI & CO (JP) | 2020-12-09 | — | — | EP | disclosed |
| WO-2020243224-A1 | A MEDICAMENT FOR TREATING MYCOBACTERIAL INFECTION CHARACTERIZED BY COMBINING A CYTOCHROME bc1 INHIBITOR WITH CLARITHROMYCIN OR AZITHROMYCIN AND CLOFAZIMINE | SHIONOGI & CO., LTD. (JP) | 2020-12-03 | — | — | WO | disclosed |
| US-20200354358-A1 | NITROGEN-CONTAINING HETEROCYCLE AND CARBOCYCLE DERIVATIVES HAVING TRKA INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2020-11-12 | — | — | US | disclosed |
| CN-107922423-B | Nitrogen-containing tricyclic derivatives having HIV replication inhibiting effect | 盐野义制药株式会社 | 2020-10-27 | — | — | CN | disclosed |
| US-10781210-B2 | Nitrogen-containing heterocycle and carbocycle derivatives having TrkA inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2020-09-22 | — | — | US | disclosed |
| CN-108291178-B | Detergent compositions comprising amylase and protease variants | 诺维信公司 | 2020-08-04 | — | — | CN | disclosed |
| EP-3670496-A2 | ACC2 INHIBITORS | Shionogi&Co., Ltd. (JP) | 2020-06-24 | — | — | EP | disclosed |
| CN-111138458-A | Nitrogen-containing tricyclic derivatives having HIV replication inhibiting effect | 盐野义制药株式会社 | 2020-05-12 | — | — | CN | disclosed |
| US-10640495-B2 | Heterocycle derivatives having TrkA inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2020-05-05 | — | — | US | disclosed |
| US-20200087302-A1 | NITROGEN-CONTAINING HETEROCYCLE AND CARBOCYCLE DERIVATIVES HAVING TRKA INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2020-03-19 | — | — | US | disclosed |
| US-20200055873-A1 | NITROGEN-CONTAINING TRICYCLIC DERIVATIVES HAVING HIV REPLICATION INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2020-02-20 | — | — | US | disclosed |
| US-10532985-B2 | Heterocycle and carbocycle derivatives having TRKA inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2020-01-14 | — | — | US | disclosed |
| EP-3572518-A1 | METHOD FOR RELEASING ALDEHYDE OR KETONE | Takasago International Corporation (JP) | 2019-11-27 | — | — | EP | disclosed |
| US-20190338216-A1 | METHOD FOR RELEASING ALDEHYDE OR KETONE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2019-11-07 | — | — | US | disclosed |
| EP-2952503-B1 | CARBOXYLIC ACID DERIVATIVES AS HIV REPLICATION INHIBITOR | SHIONOGI & CO (JP) | 2019-10-23 | — | — | EP | disclosed |
| US-10442821-B2 | Method for releasing unsaturated aldehyde or ketone | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2019-10-15 | — | — | US | disclosed |
| US-20190185494-A1 | METHOD FOR RELEASING UNSATURATED ALDEHYDE OR KETONE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2019-06-20 | — | — | US | disclosed |
| EP-3492570-A1 | METHOD FOR RELEASING UNSATURATED ALDEHYDE OR KETONE | Takasago International Corporation (JP) | 2019-06-05 | — | — | EP | disclosed |
| US-20190144396-A1 | 9-MEMBERED FUSED RING DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2019-05-16 | — | — | US | disclosed |
| CN-109563437-A | Discharge the method for unsaturated aldehydes or ketones | 高砂香料工业株式会社 | 2019-04-02 | — | — | CN | disclosed |
| US-10233156-B2 | 9-membered fused ring derivative | SHIONOGI & CO., LTD. (JP) | 2019-03-19 | — | — | US | disclosed |
| US-20190047998-A1 | NITROGEN-CONTAINING HETEROCYCLE AND CARBOCYCLE DERIVATIVES HAVING TRKA INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2019-02-14 | — | — | US | disclosed |
| US-10160727-B2 | Heterocycle and carbocycle derivatives having TrkA inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2018-12-25 | — | — | US | disclosed |
| US-20180362543-A1 | HIV REPLICATION INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2018-12-20 | — | — | US | disclosed |
| EP-3412663-A1 | NITROGEN-CONTAINING HETEROCYCLE HAVING TRKA INHIBITORY ACTIVITY, AND CARBOCYCLIC DERIVATIVE | Shionogi & Co., Ltd. (JP) | 2018-12-12 | — | — | EP | disclosed |
| US-10150728-B2 | Alkylene derivatives | SHIONOGI & CO., LTD. (JP) | 2018-12-11 | — | — | US | disclosed |
| US-20180201607-A1 | HETEROCYCLE DERIVATIVES HAVING TRKA INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2018-07-19 | — | — | US | disclosed |
| US-20180186814-A1 | TRICYCLIC COMPOUND HAVING SULFINYL OR SULFONYL | SHIONOGI & CO., LTD. (JP) | 2018-07-05 | — | — | US | disclosed |
| US-20180162876-A1 | NITROGEN-CONTAINING TRICYCLIC DERIVATIVES HAVING HIV REPLICATION INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
| EP-3330256-A1 | HETEROCYCLIC DERIVATIVE HAVING TrkA-INHIBITING ACTIVITY | Shionogi & Co., Ltd. (JP) | 2018-06-06 | — | — | EP | disclosed |
| US-9988373-B2 | Nitrogen-containing six-membered cyclic derivatives and pharmaceutical composition comprising the same | SHIONOGI & CO., LTD. (JP) | 2018-06-05 | — | — | US | disclosed |
| EP-2772480-B1 | HIV REPLICATION INHIBITOR | SHIONOGI & CO (JP) | 2018-05-23 | — | — | EP | disclosed |
| EP-3318567-A1 | TRICYCLIC COMPOUND HAVING SULFINYL OR SULFONYL | Shionogi & Co., Ltd (JP) | 2018-05-09 | — | — | EP | disclosed |
| CN-107922436-A | Tricyclic compound with sulfinyl or sulfonyl | 盐野义制药株式会社 | 2018-04-17 | — | — | CN | disclosed |
| EP-3305789-A1 | NITROGEN-CONTAINING TRICYCLIC DERIVATIVE HAVING HIV REPLICATION INHIBITORY ACTIVITY | Shionogi & Co., Ltd. (JP) | 2018-04-11 | — | — | EP | disclosed |
| US-20180079727-A1 | 9-MEMBERED FUSED RING DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2018-03-22 | — | — | US | disclosed |
| EP-3279187-A1 | 9-MEMBERED FUSED RING DERIVATIVE | Shionogi & Co., Ltd. (JP) | 2018-02-07 | — | — | EP | disclosed |
| CN-107428700-A | 9 yuan of fused-ring derivatives | 盐野义制药株式会社 | 2017-12-01 | — | — | CN | disclosed |
| US-9758513-B2 | Dihydrooxazine or oxazepine derivatives having BACE1 inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2017-09-12 | — | — | US | disclosed |
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2017-09-07 | — | — | US | disclosed |
| US-20170240512-A1 | HETEROCYCLE AND CARBOCYCLE DERIVATIVES HAVING TRKA INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2017-08-24 | — | — | US | disclosed |
| US-9725442-B2 | Heterocyclic derivative having PGD2 receptor antagonist activity | SHIONOGI & CO., LTD. (JP) | 2017-08-08 | — | — | US | disclosed |
| EP-3192794-A1 | SUSTAINED HIV PROTEASE INHIBITOR | Shionogi & Co., Ltd. (JP) | 2017-07-19 | — | — | EP | disclosed |
| WO-2017061534-A1 | DIHYDROTHIAZINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2017-04-13 | — | — | WO | disclosed |
| EP-3144311-A1 | TRICYCLIC HETEROCYCLIC DERIVATIVE HAVING HIV REPLICATION-INHIBITING EFFECT | Shionogi & Co., Ltd. (JP) | 2017-03-22 | — | — | EP | disclosed |
| US-20170073337-A1 | DIHYDROTHIAZINE AND DIHYDROOXAZINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2017-03-16 | — | — | US | disclosed |
| US-20170066759-A1 | AROMATIC 5-MEMBERED HETEROCYCLIC DERIVATIVE HAVING TRPV4-INHIBITING ACTIVITY | SHIONOGI & CO (JP) | 2017-03-09 | — | — | US | disclosed |
| EP-3129370-A1 | DIHYDROTHIAZINE AND DIHYDROOXAZINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | Shionogi & Co., Ltd. (JP) | 2017-02-15 | — | — | EP | disclosed |
| US-20170008881-A1 | DIHYDROOXAZINE OR OXAZEPINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2017-01-12 | — | — | US | disclosed |
| US-9540359-B2 | Dihydrooxazine or oxazepine derivatives having BACE1 inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-9499533-B2 | Aromatic 5-membered heterocyclic derivative having TRPV4-Inhibiting activity | SHIONOGI & CO., LTD. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20160318916-A1 | NITROGEN-CONTAINING SIX-MEMBERED CYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SHIONOGI & CO., LTD. (JP) | 2016-11-03 | — | — | US | disclosed |
| US-20160257641-A1 | NOVEL ALKYLENE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2016-09-08 | — | — | US | disclosed |
| EP-2752410-B1 | HETEROCYCLE DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONIST ACTIVITY | SHIONOGI & CO (JP) | 2016-08-31 | — | — | EP | disclosed |
| EP-3059225-A1 | NOVEL ALKYLENE DERIVATIVE | Shionogi & Co., Ltd. (JP) | 2016-08-24 | — | — | EP | disclosed |
| EP-2438989-B1 | USE OF ASYMMETRIC HYDROGENATION CATALYST | TAKASAGO PERFUMERY CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-20150361093-A1 | HIV REPLICATION INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |
| EP-2952503-A1 | HIV REPLICATION INHIBITOR | Shionogi & Co., Ltd. (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-9199959-B2 | HIV replication inhibitor | SHIONOGI & CO., LTD. (JP) | 2015-12-01 | — | — | US | disclosed |
| WO-2015156421-A1 | DIHYDROTHIAZINE AND DIHYDROOXAZINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2015-10-15 | — | — | WO | disclosed |
| US-20150266865-A1 | DIHYDROOXAZINE OR OXAZEPINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2015-09-24 | — | — | US | disclosed |
| EP-1556389-B9 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2015-09-09 | — | — | EP | disclosed |
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2015-09-03 | — | — | US | disclosed |
| EP-2912035-A1 | DIHYDROOXAZINE OR OXAZEPINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | Shionogi & Co., Ltd. (JP) | 2015-09-02 | — | — | EP | disclosed |
| US-9061959-B2 | Method for manufacturing optically active menthol | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-06-23 | — | — | US | disclosed |
| US-9000192-B2 | Catalyst for asymmetric hydrogenation and method for manufacturing optically active carbonyl compound using the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-04-07 | — | — | US | disclosed |
| EP-1556389-B3 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2015-04-01 | — | — | EP | disclosed |
| US-20150038483-A1 | AROMATIC 5-MEMBERED HETEROCYCLIC DERIVATIVE HAVING TRPV4-INHIBITING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2015-02-05 | — | — | US | disclosed |
| EP-2832731-A1 | AROMATIC HETEROCYCLIC FIVE-MEMBERED RING DERIVATIVE HAVING TRPV4 INHIBITORY ACTIVITY | Shionogi & Co., Ltd. (JP) | 2015-02-04 | — | — | EP | disclosed |
| US-20140275074-A1 | HETEROCYCLIC DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONIST ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20140249306-A1 | HIV REPLICATION INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2014-09-04 | — | — | US | disclosed |
| EP-2772480-A1 | HIV REPLICATION INHIBITOR | Shionogi & Co., Ltd. (JP) | 2014-09-03 | — | — | EP | disclosed |
| EP-2752410-A1 | HETEROCYCLE DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONIST ACTIVITY | Shionogi & Co., Ltd. (JP) | 2014-07-09 | — | — | EP | disclosed |
| WO-2014065434-A1 | DIHYDROOXAZINE OR OXAZEPINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2014-05-01 | — | — | WO | disclosed |
| US-8674144-B2 | Catalyst for asymmetric hydrogenation and method for manufacturing optically active carbonyl compound using the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-8618288-B2 | Pyrimidine compounds as serotonin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2013-12-31 | — | — | US | disclosed |
| EP-2647616-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL | Takasago International Corporation (JP) | 2013-10-09 | — | — | EP | disclosed |
| EP-2646150-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME | Takasago International Corporation (JP) | 2013-10-09 | — | — | EP | disclosed |
| US-20130253228-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-09-26 | — | — | US | disclosed |
| US-20130217895-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-08-22 | — | — | US | disclosed |
| EP-2543437-A2 | HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST | Takasago International Corporation (JP) | 2013-01-09 | — | — | EP | disclosed |
| US-20120321559-A1 | HEXAHYDRO-PYRROLO-ISOQUINOLINE COMPOUNDS | APODACA RICHARD (US) | 2012-12-20 | — | — | US | disclosed |
| US-8273762-B2 | Hexahydro-pyrrolo-isoquinoline compounds | JANSSEN PHARMACEUTICA NV (BE) | 2012-09-25 | — | — | US | disclosed |
| US-8242275-B2 | Bicyclic pyrazole compounds as antibacterial agents | JANSSEN PHARMACEUTICA NV (BE) | 2012-08-14 | — | — | US | disclosed |
| US-8232391-B2 | Bicyclic pyrazole compounds as antibacterial agents | JANSSEN PHARMACEUTICA NV (BE) | 2012-07-31 | — | — | US | disclosed |
| US-8217204-B2 | Catalyst for asymmetric hydrogenation | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| WO-2012074128-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-06-07 | — | — | WO | disclosed |
| US-20120136176-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |
| EP-2457655-A2 | Catalyst for asymmetric hydrogenation comprising peptides and method for manufacturing optically active carbonyl compound using the same | Takasago International Corporation (JP) | 2012-05-30 | — | — | EP | disclosed |
| US-8133871-B2 | Dihydropseudoerythromycin derivatives | THE KITASATO INSTITUTE (JP) | 2012-03-13 | — | — | US | disclosed |
| EP-1928461-B1 | PYRIMIDINE COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2011144983-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE | AUROBINDO PHARMA LIMITED (IN) | 2011-11-24 | — | — | WO | disclosed |
| US-8039498-B2 | Imidazole compounds | JANSSEN PHARMACEUTICA NV (BE) | 2011-10-18 | — | — | US | disclosed |
| US-8017600-B2 | Imidazole compounds | JANSSEN PHARMACEUTICA NV (BE) | 2011-09-13 | — | — | US | disclosed |
| US-8017639-B2 | Imidazole compounds | JANSSEN PHARMACEUTICA NV (BE) | 2011-09-13 | — | — | US | disclosed |
| EP-1950219-B1 | NOVEL DIHYDROPSEUDOERYTHROMYCIN DERIVATIVES | KITASATO INST (JP) | 2011-06-22 | — | — | EP | disclosed |
| US-7956066-B2 | Imidazole compounds | JANSSEN PHARMACEUTICA NV (BE) | 2011-06-07 | — | — | US | disclosed |
| US-7956071-B2 | Imidazole compounds | JANSSEN PHARMACEUTICA NV (BE) | 2011-06-07 | — | — | US | disclosed |
| US-7956057-B2 | Imidazole compounds | JANSSEN PHARMACEUTICA NV (BE) | 2011-06-07 | — | — | US | disclosed |
| US-7951808-B2 | Imidazole compounds | JANSSEN PHARMACEUTICA NV (BE) | 2011-05-31 | — | — | US | disclosed |
| EP-1824832-B1 | ARYL-SUBSTITUTED BENZIMIDAZOLE AND IMIDAZOPYRIDINE ETHERS AS ANTI-CANCER AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2011-04-27 | — | — | EP | disclosed |
| US-7928131-B2 | Imidazole compounds | JANSSEN PHARMACEUTICA NV (BE) | 2011-04-19 | — | — | US | disclosed |
| US-7902179-B2 | Suppress tumor necrosis factor; Crohn's disease; imflammatory bowel disorders; sepsis; autoimmune disease | AJINOMOTO CO., INC. (JP) | 2011-03-08 | — | — | US | disclosed |
| EP-1831173-B1 | TETRAHYDROISOQUINOLINE COMPOUNDS FOR TREATMENT OF CNS DISORDERS | JANSSEN PHARMACEUTICA NV (BE) | 2011-01-26 | — | — | EP | disclosed |
| US-20100324338-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |
| US-7855292-B2 | Cholecystokinin (CCK) receptor ligands; antagonists; 3-(5-Bromo-thiophen-2-yl)-2-[4-chloro-2-(quinoxaline-5-sulfonylamino)-benzoylamino]-propionic acid methy; pain, drug dependence, anxiety, panic attack, schizophrenia, pancreatic disorders, secretory disorders, ulcers, cancers; improved pharmacokinetics | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-21 | — | — | US | disclosed |
| US-7842810-B2 | 2,3-Dihydro-benzo[1,4]dioxine-6-carboxylic acid [2-(6-methoxy-quinolin-4-yl)-4,5,6,7-tetrahydro-2H-indazol-5-yl]-amide | JANSSEN PHARMACEUTICA, NV (BE) | 2010-11-30 | — | — | US | disclosed |
| US-20100292240-A1 | SULFONAMIDE COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-18 | — | — | US | disclosed |
| US-20100280240-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS | ALLISON BRETT D | 2010-11-04 | — | — | US | disclosed |
| US-20100274005-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS | ALLISON BRETT D | 2010-10-28 | — | — | US | disclosed |
| US-20100274004-A1 | BICYCLIC PIRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS | ALLISON BRETT D | 2010-10-28 | — | — | US | disclosed |
| US-20100261898-A1 | IMIDAZOLE COMPOUNDS | BUZARD DANIEL J | 2010-10-14 | — | — | US | disclosed |
| US-20100261899-A1 | IMIDAZOLE COMPOUNDS | BUZARD DANIEL J | 2010-10-14 | — | — | US | disclosed |
| US-7807837-B2 | Scalable synthesis of imidazole derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-05 | — | — | US | disclosed |
| US-20100240648-A1 | HEXAHYDRO-PYRROLO-ISOQUINOLINE COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2010-09-23 | — | — | US | disclosed |
| EP-1285651-B1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | TAKEDA PHARMACEUTICAL (JP) | 2010-09-01 | — | — | EP | disclosed |
| US-7754882-B2 | Hexahydro-pyrrolo-isoquinoline compounds | JANSSEN PHARMACEUTICA NV (BE) | 2010-07-13 | — | — | US | disclosed |
| EP-1663245-B1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2010-04-07 | — | — | EP | disclosed |
| US-20100016281-A1 | PYRIMIDINE COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-01-21 | — | — | US | disclosed |
| US-7645758-B2 | Heterocyclic compounds | Janssen Pharmaceutica, N.Y. (BE) | 2010-01-12 | — | — | US | disclosed |
| US-7601868-B2 | Such as 4-(cyclopropylmethoxy)-N-(2-{4-[1-(1-pyrrolidinyl)ethyl]phenyl}ethyl)benzamide having melanin-concentrating hormone antagonistic action, for prophylaxis and/or treatment of obesity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-13 | — | — | US | disclosed |
| US-7598255-B2 | Pyrimidine compounds as serotonin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2009-10-06 | — | — | US | disclosed |
| EP-1737297-A4 | IMIDAZOLE COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-15 | — | — | EP | disclosed |
| EP-1781617-A4 | ALPHA, BETA-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-24 | — | — | EP | disclosed |
| US-20090143591-A1 | SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-04 | — | — | US | disclosed |
| US-20090131341-A1 | Novel Dihydropseudoerythromycin Derivatives | APHOENIX, INC. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1747203-A4 | SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-22 | — | — | EP | disclosed |
| US-7507756-B2 | Scalable synthesis of imidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-24 | — | — | US | disclosed |
| US-7504426-B2 | Heterocyclic compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-17 | — | — | US | disclosed |
| US-20090012054-A1 | Cephem Compounds and Use as Antimicrobial Agents | ASTELLAS PHARMA INC. (JP) | 2009-01-08 | — | — | US | disclosed |
| US-7465808-B2 | CCK-1 receptor modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-12-16 | — | — | US | disclosed |
| EP-1994035-A1 | CEPHEM COMPOUNDS AND USE AS ANTIMICROBIAL AGENTS | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-20080262219-A1 | NOVEL CRYSTAL OF 7-[2-[(2-AMINOTHIAZOL-4-YL)-2-HYDROXYIMINOACETAMIDE-3-VINYL-3-CEPHEM-4-CARBOXYLIC ACID (SYN ISOMER) AND METHOD FOR PREPARATION THEREOF | IMAI EIJI | 2008-10-23 | — | — | US | disclosed |
| EP-1365755-B1 | USE OF PYRIMIDINE NUCLEOSIDES AND/OR THE PRODRUGS THEREOF FOR COMBATING THE SIDE-EFFECTS OF HAART (HIGHLY ACTIVE ANTI-RETROVIRAL THERAPY) AND OTHER ANTI-VIRAL THERAPIES | PHARMA NORD APS (DK) | 2008-10-22 | — | — | EP | disclosed |
| EP-1899334-B1 | NAPHTHYRIDINE COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | EP | disclosed |
| US-7417054-B2 | Naphthyridine compounds | JANSSEN PHARMACEUTICA N.V. (BG) | 2008-08-26 | — | — | US | disclosed |
| WO-2008100564-A1 | LTA4H MODULATORS AND USES THEROF | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-21 | — | — | WO | disclosed |
| EP-1660492-B1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-20 | — | — | EP | disclosed |
| US-20080194630-A1 | Leukotriene A-4 hydrolase inhibitors; antiinflammatory agents; skin disorders; analgesics; stroke; anticancer agents; antiallergens; rhinitis;cystic fibrosis;sepsis | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-14 | — | — | US | disclosed |
| EP-1660491-B1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-06 | — | — | EP | disclosed |
| EP-1950219-A1 | NOVEL DIHYDROPSEUDOERYTHROMYCIN DERIVATIVES | THE KITASATO INSTITUTE (JP) | 2008-07-30 | — | — | EP | disclosed |
| EP-1928461-A1 | PYRIMIDINE COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-11 | — | — | EP | disclosed |
| US-20080132511-A1 | Cholecystokinin (CCK) receptor ligands; antagonists; 3-(5-Bromo-thiophen-2-yl)-2-[4-chloro-2-(quinoxaline-5-sulfonylamino)-benzoylamino]-propionic acid methy; pain, drug dependence, anxiety, panic attack, schizophrenia, pancreatic disorders, secretory disorders, ulcers, cancers; improved pharmacokinetics | JANSSEN PHARMACEUTICA NV (BE) | 2008-06-05 | — | — | US | disclosed |
| EP-1899334-A2 | NAPHTHYRIDINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-19 | — | — | EP | disclosed |
| EP-1893613-A1 | HEXAHYDRO-PYRROLO-ISOQUINOLINE COMPOUNDS FOR THE TREATMENT OF CNS DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-05 | — | — | EP | disclosed |
| EP-1868605-A2 | PHENYL AND PYRIDYL LTA4H MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2007-12-26 | — | — | EP | disclosed |
| EP-1863483-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS | Janssen Pharmaceutica, N.V. (BE) | 2007-12-12 | — | — | EP | disclosed |
| US-20070270586-A1 | NOVEL CRYSTAL OF 7-[2-[(2-AMINOTHIAZOL-4-YL)-2-HYDROXYIMINOACETAMIDE-3-VINYL-3-CEPHEM-4-CARBOXYLIC ACID (SYN ISOMER) AND METHOD FOR PREPARATION THEREOF | IMAI EIJI | 2007-11-22 | — | — | US | disclosed |
| US-7297816-B2 | Sulfonamide compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-20 | — | — | US | disclosed |
| US-20070265250-A1 | Imidazole compounds | BUZARD DANIEL J | 2007-11-15 | — | — | US | disclosed |
| WO-2007119511-A1 | CEPHEM COMPOUNDS AND USE AS ANTIMICROBIAL AGENTS | ASTELLAS PHARMA INC. (JP) | 2007-10-25 | — | — | WO | disclosed |
| EP-1831173-A1 | TETRAHYDROISOQUINOLINE COMPOUNDS FOR TREATMENT OF CNS DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-09-12 | — | — | EP | disclosed |
| EP-1824832-A1 | ARYL-SUBSTITUTED BENZIMIDAZOLE AND IMIDAZOPYRIDINE ETHERS AS ANTI-CANCER AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-29 | — | — | EP | disclosed |
| US-20070185131-A1 | Heterocyclic Compounds | JANSSEN PHARMACEUTICA, N.V. | 2007-08-09 | — | — | US | disclosed |
| US-20070185120-A1 | Heterocyclic Compounds | JANSSEN PHARMACEUTICA, N.V. | 2007-08-09 | — | — | US | disclosed |
| US-7253200-B2 | Using in leukocyte recruitment inhibition, in modulating H4 receptor expression, and in treating conditions such as inflammation, H4 receptor-mediated conditions | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-08-07 | — | — | US | disclosed |
| US-7250427-B2 | Aryl-substituted benzimidazole and imidazopyridine ethers | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-07-31 | — | — | US | disclosed |
| US-20070173512-A1 | Imidazole compounds | JANSSEN PHARMACEUTICA, N.V. | 2007-07-26 | — | — | US | disclosed |
| US-20070173498-A1 | Melanin concentrating hormone antagonist | KATO KANEYOSHI | 2007-07-26 | — | — | US | disclosed |
| US-20070173509-A1 | Imidazole compounds | JANSSEN PHARMACEUTICA, N.V. | 2007-07-26 | — | — | US | disclosed |
| US-20070173510-A1 | Imidazole compounds | JANSSEN PHARMACEUTICA, N.V. | 2007-07-26 | — | — | US | disclosed |
| US-20070173513-A1 | Imidazole compounds | JANSSEN PHARMACEUTICA, N.V. | 2007-07-26 | — | — | US | disclosed |
| EP-1556389-B1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2007-07-25 | — | — | EP | disclosed |
| US-20070149541-A1 | Imidazole compounds | JANSSEN PHARMACEUTICA, N.V. | 2007-06-28 | — | — | US | disclosed |
| EP-1797083-A1 | SULFONAMIDE COMPOUNDS | Janssen Pharmaceutica, N.V. (BE) | 2007-06-20 | — | — | EP | disclosed |
| US-7229986-B2 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LTD. (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7226938-B2 | Heterocyclic compounds | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-06-05 | — | — | US | disclosed |
| US-20070106073-A1 | Novel crystal of 7-[2-[(2-aminothiazol-4-yl)-2-hydroxyiminoacetamide-3-vinyl-3-cephem-4-carboxylic acid (syn isomer) and method for preparation thereof | ACS DOBFAR S.P.A. (IT) | 2007-05-10 | — | — | US | disclosed |
| EP-1781617-A2 | ALPHA, BETA-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-09 | — | — | EP | disclosed |
| US-7192943-B2 | Cephem compounds | ASTELLAS PHARMA INC. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20070037786-A1 | Cephem compounds | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2007-02-15 | — | — | US | disclosed |
| WO-2007019083-A1 | PYRIMIDINE COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-02-15 | — | — | WO | disclosed |
| US-20070032481-A1 | PYRIMIDINE COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2007-02-08 | — | — | US | disclosed |
| EP-1747203-A1 | SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-31 | — | — | EP | disclosed |
| EP-1320367-A4 | PROCESS FOR THE PREPARATION OF DINAPSOLINE | PURDUE RESEARCH FOUNDATION (US) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005012297-A9 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2007-01-04 | — | — | WO | disclosed |
| EP-1737297-A2 | IMIDAZOLE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-03 | — | — | EP | disclosed |
| WO-2006138714-A2 | NAPHTHYRIDINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-12-28 | — | — | WO | disclosed |
| WO-2006138604-A1 | HEXAHYDRO-PYRROLO-ISOQUINOLINE COMPOUNDS FOR THE TREATMENT OF CNS DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-12-28 | — | — | WO | disclosed |
| US-20060293316-A1 | HEXAHYDRO-PYRROLO-ISOQUINOLINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-12-28 | — | — | US | disclosed |
| US-20060287292-A1 | NAPHTHYRIDINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-12-21 | — | — | US | disclosed |
| US-7129232-B2 | For therapy of of infectious diseases | ASTELLAS PHARMA INC. (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20060223826-A1 | Indole derivatives as somatostatin agonists or antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED INTELLECTUAL PROPERTY DEPARTMENT (JP) | 2006-10-05 | — | — | US | disclosed |
| WO-2006105304-A2 | PHENYL AND PYRIDYL LTA4H MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | WO | disclosed |
| US-20060223810-A1 | Bicyclic pyrazole compounds as antibacterial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | US | disclosed |
| WO-2006105289-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | WO | disclosed |
| US-20060223792-A1 | Phenyl and pyridyl LTA4H modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | US | disclosed |
| US-7115750-B1 | Melanin concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20060194837-A1 | Tetrahydroisoquinoline compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-08-31 | — | — | US | disclosed |
| WO-2006066197-A1 | TETRAHYDROISOQUINOLINE COMPOUNDS FOR TREATMENT OF CNS DISORDERS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-06-22 | — | — | WO | disclosed |
| US-20060128690-A1 | Amine derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1663245-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
| EP-1660492-A1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2006-05-31 | — | — | EP | disclosed |
| EP-1660491-A1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-31 | — | — | EP | disclosed |
| EP-1651638-A1 | PYRIDYL PIPERAZINYL UREAS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-03 | — | — | EP | disclosed |
| EP-1543011-B1 | THIENOPYRROLYL AND FURANOPYRROLYL COMPOUNDS AND THEIR USE AS HISTAMINE H4 RECEPTOR LIGANDS | JANSSEN PHARMACEUTICA NV (BE) | 2006-05-03 | — | — | EP | disclosed |
| US-7037931-B2 | Corticotropin releasing factor moderator; analgesics; drug abruse, drug dependency; schizophrenia | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-02 | — | — | US | disclosed |
| US-RE39088-E1 | Amide compounds and use of the same | JAPAN TOBACCO, INC. (JP) | 2006-05-02 | — | — | US | disclosed |
| WO-2006036670-A1 | SULFONAMIDE COMPOUNDS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-04-06 | — | — | WO | disclosed |
| EP-1641762-A2 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-04-05 | — | — | EP | disclosed |
| US-20060069286-A1 | Sulfonamide compounds | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-03-30 | — | — | US | disclosed |
| US-20060014817-A1 | CCK-1 receptor modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-01-19 | — | — | US | disclosed |
| WO-2006004742-A2 | α, β-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION | JANSSEN PHARAMCEUTICA N.V. (BE) | 2006-01-12 | — | — | WO | disclosed |
| WO-2006004791-A1 | ARYL-SUBSTITUTED BENZIMIDAZOLE AND IMIDAZOPYRIDINE ETHERS AS ANTI-CANCER AGENTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-01-12 | — | — | WO | disclosed |
| US-20060004195-A1 | Alpha,beta-unsaturated esters and acids by stereoselective dehydration | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-01-05 | — | — | US | disclosed |
| US-20060004039-A1 | Aryl-substituted benzimidazole and imidazopyridine ethers | JANSSEN PHARMACEUTICA, N. V. (BE) | 2006-01-05 | — | — | US | disclosed |
| EP-1609793-A1 | NOVEL CRYSTAL OF 7- 2-(2-AMINOTHIAZOLE-4-YL)-2-HYDROXYIMINOA CETAMIDO-3-VINYL-3-CEPHEM-4-CARBOXYLIC ACID (SYN ISOMER) AND METHOD FOR PREPARATION THEREOF | ACS DOBFAR S.p.A. (IT) | 2005-12-28 | — | — | EP | disclosed |
| WO-2005110998-A1 | SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-11-24 | — | — | WO | disclosed |
| US-20050261309-A1 | Imidazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-11-24 | — | — | US | disclosed |
| US-20050250948-A1 | Scalable synthesis of imidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-11-10 | — | — | US | disclosed |
| EP-1593667-A1 | AMINE DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2005-11-09 | — | — | EP | disclosed |
| US-20050245571-A1 | Amine derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-11-03 | — | — | US | disclosed |
| WO-2005092066-A2 | IMIDAZOLE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-10-06 | — | — | WO | disclosed |
| US-20050209213-A1 | Quinoline compound | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-22 | — | — | US | disclosed |
| WO-2005082459-A2 | METHOD OF DECREASING BLOOD CELLS | JAPAN TOBACCO INC. (JP) | 2005-09-09 | — | — | WO | disclosed |
| US-20050187221-A1 | Method of treating ischemia reperfusion injury | JAPAN TOBACCO INC. (JP) | 2005-08-25 | — | — | US | disclosed |
| EP-1562898-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
| US-6930185-B2 | Melanin-concentrating hormone antagonist | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-16 | — | — | US | disclosed |
| EP-1556389-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2005-07-27 | — | — | EP | disclosed |
| EP-1545532-A2 | HETEROCYCLIC COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-06-29 | — | — | EP | disclosed |
| EP-1543011-A2 | THIENOPYRROLYL AND FURANOPYRROLYL COMPOUNDS AND THEIR USE AS HISTAMINE H4 RECEPTOR LIGANDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-06-22 | — | — | EP | disclosed |
| US-20050130941-A1 | Methods of treating alzheimer's disease | PHARMACIA & UPJOHN COMPANY LLC | 2005-06-16 | — | — | US | disclosed |
| EP-0849256-B1 | AMIDE COMPOUNDS AND USE OF THE SAME | JAPAN TOBACCO INC (JP) | 2005-06-08 | — | — | EP | disclosed |
| US-20050096306-A1 | Cephem compounds | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-05-05 | — | — | US | disclosed |
| US-6888001-B2 | Selective modulators of the nicotinic acetylcholine receptor useful in the treatment of pain, Alzheimer's disease, memory loss or dementia or loss of motor function. | LEE JUNG S (US) | 2005-05-03 | — | — | US | disclosed |
| EP-1525190-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-04-27 | — | — | EP | disclosed |
| WO-2005027909-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2005-03-31 | — | — | WO | disclosed |
| US-6867297-B1 | Process for synthesizing 4-substituted azetidinone derivatives | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-03-15 | — | — | US | disclosed |
| US-20050049241-A1 | Pyridyl piperazinyl ureas | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-03 | — | — | US | disclosed |
| US-20050043379-A1 | LTA4H Modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-02-24 | — | — | US | disclosed |
| US-20050043378-A1 | Leukotriene hydrolases inhibitors; antiinflamamtory agents; inflamamtory bowel disorders; antihistamines; chronic obstructive pulmonary diseases; multiple sclerosis; antiarthritic agents | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-02-24 | — | — | US | disclosed |
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| WO-2005014580-A1 | PYRIDYL PIPERAZINYL UREAS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-02-17 | — | — | WO | disclosed |
| WO-2005012297-A1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-10 | — | — | WO | disclosed |
| WO-2005012296-A1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-10 | — | — | WO | disclosed |
| US-20050026903-A1 | CCK-1 receptor modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-03 | — | — | US | disclosed |
| US-20050020565-A1 | Pyrazole compound; gastrointestinal disorders; central nervous system disorders | JONES TODD K (US) | 2005-01-27 | — | — | US | disclosed |
| WO-2005005393-A2 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-01-20 | — | — | WO | disclosed |
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-1447402-A1 | QUINOLINE COMPOUND | Takeda Chemical Industries, Ltd. (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-1445266-A2 | Photoresist copolymer | Daicel Chemical Industries, Ltd. (JP) | 2004-08-11 | — | — | EP | disclosed |
| EP-1107965-B1 | PYRIDYL ETHERS AND THIOETHERS AS LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTOR AND ITS THERAPEUTIC APPLICATION | ORTHO MCNEIL PHARM INC (US) | 2004-08-11 | — | — | EP | disclosed |
| US-20040147546-A1 | Suppress tumor necrosis factor; Crohn's disease; imflammatory bowel disorders; sepsis; autoimmune disease | AJINOMOTO CO., INC. (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1437351-A1 | AMINE DERIVATIVE | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
| US-20040132994-A1 | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-07-08 | — | — | US | disclosed |
| EP-0956000-A4 | SYNTHESIS OF GLYCOPHOSPHOLIPID AND PEPTIDE-PHOSPHOLIPID CONJUGATES AND USES THEREOF | UNIV EMORY (US) | 2004-06-09 | — | — | EP | disclosed |
| WO-2004046107-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-03 | — | — | WO | disclosed |
| US-20040092436-A1 | Immunosuppressive imidazole derivatives and their combination preparations with tacrolimus of cyclosporins | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 2004-05-13 | — | — | US | disclosed |
| WO-2004039814-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2004-05-13 | — | — | WO | disclosed |
| EP-1063235-B1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LTD (JP) | 2004-05-12 | — | — | EP | disclosed |
| EP-0990646-B1 | PROCESS FOR PREPARING 3-(7-AMIDINO-2-NAPHTHYL)-2-PHENYLPROPIONIC ACID DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-20040077628-A1 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-22 | — | — | US | disclosed |
| US-20040067983-A1 | CCK-1 receptor modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-04-08 | — | — | US | disclosed |
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
| US-20040058934-A1 | Heterocyclic compounds | JANSSEN PHARMACEUTIC, N.V. (BE) | 2004-03-25 | — | — | US | disclosed |
| WO-2004022060-A2 | (1H-BENZOIMIDAZOL-2-YL)-(PIPERAZINYL)-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS HISTAMINE H4-RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-03-18 | — | — | WO | disclosed |
| WO-2004022537-A2 | THIENOPYRROLYL AND FURANOPYRROLYL COMPOUNDS AND THEIR USE AS HISTAMINE H4 RECEPTOR LIGANDS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-03-18 | — | — | WO | disclosed |
| US-20040048878-A1 | Cyclopentathienopyrroles and cyclopentafuranopyrroles for treating disorders and conditions mediated by the histamine H4 receptor, including allergic rhinitis. | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-03-11 | — | — | US | disclosed |
| EP-1396493-A1 | HETEROCYCLIC COMPOUNDS | Ajinomoto Co., Inc. (JP) | 2004-03-10 | — | — | EP | disclosed |
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2004007463-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-01-22 | — | — | WO | disclosed |
| EP-1365755-A2 | USE OF PYRIMIDINE NUCLEOSIDES AND/OR THE PRODRUGS THEREOF FOR COMBATING THE SIDE-EFFECTS OF HAART (HIGHLY ACTIVE ANTI-RETROVIRAL THERAPY) AND OTHER ANTI-VIRAL THERAPIES | Walker, Ulrich (DE) | 2003-12-03 | — | — | EP | disclosed |
| US-6645975-B1 | Reducing, deprotecting and optionally alkylating chemical intermediates to form 8,9-dihydroxy-2,3,7,11b-tetrahydro-1H-naphtho(1,2,3-de)isoquinoline, used as dopamine receptor agonists | PURDUE RESEARCH FOUNDATION | 2003-11-11 | — | — | US | disclosed |
| US-20030207858-A1 | Selective modulators of the nicotinic acetylcholine receptor useful in the treatment of pain, Alzheimer's disease, memory loss or dementia or loss of motor function. | LEE JUNG S (US) | 2003-11-06 | — | — | US | disclosed |
| US-20030186976-A1 | Benzofurylpyrone derivatives | TEIJIN LIMITED, MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2003-10-02 | — | — | US | disclosed |
| US-20030180662-A1 | Acid-sensitive compound and resin composition for photoresist | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| US-20030158177-A1 | Treating or preventing obesity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| US-6589984-B1 | Blood cholesterol and triglycerides (TG) themselves are generally insoluble in blood, and they exist as lipoproteins by binding with apolipoproteins. In the body, triglycerides are biosynthesized primarily in the liver from acetyl CoA as | TEIJIN LIMITED (JP) | 2003-07-08 | — | — | US | disclosed |
| EP-1320367-A1 | PROCESS FOR THE PREPARATION OF DINAPSOLINE | PURDUE RESEARCH FOUNDATION (US) | 2003-06-25 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |
| EP-0638552-B1 | PROCESS FOR SYNTHESIZING 4-SUBSTITUTED AZETIDINONE DERIVATIVE | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6562847-B1 | Useful in the treatment of pain, Alzheimer's disease, memory loss or dementia or loss of motor function | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-05-13 | — | — | US | disclosed |
| EP-1304322-A2 | Carboxylic acid compound and use thereof | Japan Tobacco Inc. (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0937726-B1 | INTERMEDIATES FOR THE PREPARATION OF DUOCARMYCIN SA AND DERIVATIVES THEREOF, AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | KYORIN SEIYAKU KK (JP) | 2003-03-12 | — | — | EP | disclosed |
| EP-0989135-B1 | NOVEL PHOSPHINOPYRROLIDINE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | DAIICHI FINE CHEM CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| EP-1285651-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-26 | — | — | EP | disclosed |
| EP-1283199-A1 | MELANIN-CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2003-02-12 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| US-6482827-B1 | Matrix metalloproteinase inhibitors | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-11-19 | — | — | US | disclosed |
| EP-0925299-B1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| WO-2002069943-A2 | USE OF PYRIMIDINE NUCLEOSIDES AND/OR THE PRODRUGS THEREOF FOR COMBATING THE SIDE-EFFECTS OF HAART (HIGHLY ACTIVE ANTI-RETROVIRAL THERAPY) AND OTHER ANTI-VIRAL THERAPIES | WALKER ULRICH (DE) | 2002-09-12 | — | — | WO | disclosed |
| EP-1227090-A1 | AMINE DERIVATIVES | Tadeka Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |
| US-6420561-B1 | Amide compounds and use thereof | JAPAN TOBACCO INC. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1218336-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-1214092-A2 | METHOD OF POTENTIATING CHEMOTHERAPY AND TREATING SOLID TUMORS | Wyeth (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |
| US-6355640-B1 | TREATMENT OF HYPERTENSION, UROGENITAL DISORDERS AND FORMED BY WITTIG REACTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| US-6353122-B1 | IN CYCLOHEXANONE WITH POTASSIUM PEROXYMONOSULFATE AND SUBSEQUENT REARRANGEMENT TO PROVIDE THE CORRESPONDING CYCLOBUTANONE | BRISTOL-MYERS SQUIBB COMPANY | 2002-03-05 | — | — | US | disclosed |
| WO-2002013827-A1 | PROCESS FOR THE PREPARATION OF DINAPSOLINE | PURDUE RESEARCH FOUNDATION (US) | 2002-02-21 | — | — | WO | disclosed |
| US-6344559-B1 | QUINAZOLINE DERIVATIVE, SILYLATING AGENT AND A CHLOROALKYL CARBOXY COMPOUND, THEN DESILYLATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-05 | — | — | US | disclosed |
| EP-1160243-A1 | PROCESS FOR PRODUCING QUINAZOLINE DERIVATIVE OR SALT THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-05 | — | — | EP | disclosed |
| EP-1107965-A1 | PYRIDYL ETHERS AND THIOETHERS AS LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTOR AND ITS THERAPEUTIC APPLICATION | Ortho-McNeil Pharmaceutical, Inc. (US) | 2001-06-20 | — | — | EP | disclosed |
| US-6229019-B1 | Phosphinopyrroline compounds and process for producing the same | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-08 | — | — | US | disclosed |
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |
| WO-2001021577-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | disclosed |
| WO-2001019399-A2 | METHOD OF POTENTIATING CHEMOTHERAPY AND TREATING SOLID TUMORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-03-22 | — | — | WO | disclosed |
| EP-1067926-A2 | IMMUNOSUPPRESSIVE IMIDAZOLE DERIVATIVES AND THEIR COMBINATION PREPARATIONS WITH TACROLIMUS OR CYCLOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6174887-B1 | Amide compounds and use of the same | JAPAN TOBACCO INC. (JP) | 2001-01-16 | — | — | US | disclosed |
| US-6171614-B1 | REDUCTIVE AMINATION; LIPOSOMES | EMORY UNIVERSITY | 2001-01-09 | — | — | US | disclosed |
| EP-1063235-A1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-6124456-A | Pyrazolopyridine compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-26 | — | — | US | disclosed |
| EP-1010695-A1 | PROCESS FOR PRODUCING QUINAZOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-06-21 | — | — | EP | disclosed |
| US-6071532-A | SYNTHETIC VACCINES; IMMUNOLOGY; MEDICAL DIAGNOSIS | EMORY UNIVERSITY (US) | 2000-06-06 | — | — | US | disclosed |
| US-6066742-A | Intermediates for the preparation of duocarmycin SA and derivatives thereof, and process for the production of the intermediates | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| EP-1000924-A1 | ACID-SENSITIVE COMPOUND AND RESIN COMPOSITION FOR PHOTORESIST | Daichel Chemical Industries Ltd (JP) | 2000-05-17 | — | — | EP | disclosed |
| EP-0989135-A1 | NOVEL PHOSPHINOPYRROLIDINE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-03-29 | — | — | EP | disclosed |
| WO-2000010997-A1 | PYRIDYL ETHERS AND THIOETHERS AS LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTOR AND ITS THERAPEUTIC APPLICATION | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-03-02 | — | — | WO | disclosed |
| US-6008228-A | COMPRISING A MIXTURE OF CARRIER MONOGLYCERIDES OF MEDIUM CHAIN-FATTY ACIDS | HOFFMAN-LA ROCHE INC. (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0956000-A1 | SYNTHESIS OF GLYCOPHOSPHOLIPID AND PEPTIDE-PHOSPHOLIPID CONJUGATES AND USES THEREOF | EMORY UNIVERSITY (US) | 1999-11-17 | — | — | EP | disclosed |
| WO-1999051215-A2 | IMMUNOSUPPRESSIVE IMIDAZOLE DERIVATIVES AND THEIR COMBINATION PREPARATIONS WITH TACROLIMUS OR CYCLOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-14 | — | — | WO | disclosed |
| EP-0946587-A2 | NEW AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5962660-A | COMPOUND WHICH SUPPRESSES SELECTIN-MEDIATED CELLULAR ADHESION; FOR STABLE ANTIINFLAMMATORY AGENTS WITH BETTER BIOAVAILABILITY AND GREATER ACTIVITY WHICH ARE EASIER TO SYNTHESIZE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0937726-A1 | INTERMEDIATES FOR THE PREPARATION OF DUOCARMYCIN SA AND DERIVATIVES THEREOF, AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1999-08-25 | — | — | EP | disclosed |
| EP-0925289-A1 | MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-06-30 | — | — | EP | disclosed |
| EP-0925299-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-06-30 | — | — | EP | disclosed |
| EP-0920414-A1 | MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-06-09 | — | — | EP | disclosed |
| WO-1999002510-A1 | MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-01-21 | — | — | WO | disclosed |
| WO-1998038184-A1 | A METHOD FOR EPOXIDATION OF 3-METHYLENECYCLOPROPANES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-09-03 | — | — | WO | disclosed |
| US-5773530-A | USEFUL AS PSYCHOSTIMULANTS, ANTIHYPERTENSIVE AGENTS AND REMEDIES FOR RENAL FAILURE, DIURETICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| WO-1998027108-A2 | NEW AMIDE COMPOUNDS AND THEIR USE AS NITRIC OXIDE SYNTHASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-25 | — | — | WO | disclosed |
| EP-0849256-A1 | AMIDE COMPOUNDS AND USE OF THE SAME | Japan Tobacco Inc. (JP) | 1998-06-24 | — | — | EP | disclosed |
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| US-5747463-A | SELECTIN ANTAGONISTS; ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| WO-1998016198-A1 | SYNTHESIS OF GLYCOPHOSPHOLIPID AND PEPTIDE-PHOSPHOLIPID CONJUGATES AND USES THEREOF | EMORY UNIVERSITY (US) | 1998-04-23 | — | — | WO | disclosed |
| EP-0605149-B1 | Recording sheet | JUJO PAPER CO LTD (JP) | 1998-04-22 | — | — | EP | disclosed |
| EP-0594540-B1 | Antiretroviral acyl compounds | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| EP-0831826-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| WO-1998003507-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-29 | — | — | WO | disclosed |
| WO-1997049674-A1 | MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-12-31 | — | — | WO | disclosed |
| US-5686426-A | Dicarboxymethylated glycolipid derivatives as cell adhesion inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1997041128-A1 | 3-PYRAZOLIOMETHYLCEPHEM COMPOUNDS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-06 | — | — | WO | disclosed |
| US-5672701-A | 4-substituted alkyl carbapenem antibiotics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| US-5670497-A | RETROVIRAL PROTEASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |
| US-5663151-A | ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| US-5658945-A | ANTICANCER AGENT; AIDS THERAPY; CONTROLLING INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1997-08-19 | — | — | US | disclosed |
| US-5633280-A | ACCELERATED RECOVERY FROM CHEMOTHERAPY, RADIATION TREATMENT, BONE MARROW TRANSPLANTATION, INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| US-5623078-A | Process for producing an intermediate of a new quinolone compound | CHISSO CORPORATION (JP) | 1997-04-22 | — | — | US | disclosed |
| US-5616612-A | THERAPY FOR CANCER, AIDS, ANEMIA, INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1997-04-01 | — | — | US | disclosed |
| US-5602275-A | MAY BE USED TO ACCELERATE RECOVERY FROM NEUTROPENIA ACCOMPANYING RADIO- OR CHEMOTHERAPY, BONE MARROW TRANSPLANTATION OR INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1997-02-11 | — | — | US | disclosed |
| JP-H0912546-A | AZABICYCLOCYCLIC COMPOUND AND ITS PRODUCTION | CHISSO CORP | 1997-01-14 | — | — | JP | disclosed |
| WO-1996039142-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1996-12-12 | — | — | WO | disclosed |
| EP-0652228-B1 | Urethanes and ureas that induce cytokine production | AMERICAN CYANAMID CO (US) | 1996-10-23 | — | — | EP | disclosed |
| EP-0737193-A1 | PYRAZOLOPYRIDINE ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-16 | — | — | EP | disclosed |
| US-5565433-A | ADMINISTERING IN TREATMENT AND PREVENTION OF INFLAMMATORY DISEASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0521827-B1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA GEIGY AG (CH) | 1996-09-25 | — | — | EP | disclosed |
| EP-0604368-B1 | Anti retroviral hydrazine derivatives | CIBA GEIGY AG (CH) | 1996-09-18 | — | — | EP | disclosed |
| US-5545662-A | USED TO ACCELERATE RECOVERY FROM NEUTROPENIA ACCOMPANYING RADIO OR CHEMOTHERAPY, BONE MARROW TRANSPLANTATION, OR INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1996023798-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-08 | — | — | WO | disclosed |
| EP-0719787-A1 | Dicarboxymethylated glycolipid derivatives as cell adhesion inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-07-03 | — | — | EP | disclosed |
| EP-0470355-B1 | Process for the preparation of deoxynucleosides | AMERICAN CYANAMID CO (US) | 1996-06-05 | — | — | EP | disclosed |
| US-5523410-A | Intermediate for synthesis and production of amino acid derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0708760-A1 | CYCLIC HYDRAZINE COMPOUNDS | Novartis AG (CH) | 1996-05-01 | — | — | EP | disclosed |
| US-5491132-A | HYPOTENSIVE AGENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| CN-1030918-C | 4-substituted alkyl carbapenem antibiotics | BRISTOL MYERS SQUIBB CO (US) | 1996-02-07 | — | — | CN | disclosed |
| US-5482913-A | CARBONATE TYPE BLOCKED COLOR DEVELOPER, LASER RECORDING | NIPPON PAPER INDUSTRIES, CO., LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0671407-A2 | Sulfated alpha-glycolipid derivatives as cell adhesion inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-09-13 | — | — | EP | disclosed |
| EP-0671406-A2 | Sulfated beta-glycolipid derivatives as cell adhesion inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995018128-A1 | PYRAZOLOPYRIDINE ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-06 | — | — | WO | disclosed |
| EP-0652228-A1 | Urethanes and ureas that induce cytokine production | AMERICAN CYANAMID COMPANY (US) | 1995-05-10 | — | — | EP | disclosed |
| US-5409919-A | Pharmaceutically acceptable salt of 7B-[2-(5-amino-1,2,4-thio-diazol-3-yl)-2(Z)-metho-xyiminoacetamido]-3-[(imidazo[1,2-b]pyridazinium-1-yl)methyl]-3-cephem-4-carboxylate and composition comprising same | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0648747-A1 | NOVEL INTERMEDIATE FOR SYNTHESIS AND PRODUCTION OF AMINO ACID DERIVATIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0638552-A1 | PROCESS FOR SYNTHESIZING 4-SUBSTITUTED AZETIDINONE DERIVATIVE | SUNTORY LIMITED (JP) | 1995-02-15 | — | — | EP | disclosed |
| WO-1995002582-A1 | CYCLIC HYDRAZINE COMPOUNDS | CIBA-GEIGY AG (CH) | 1995-01-26 | — | — | WO | disclosed |
| EP-0300189-B1 | New amino acid derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-11-02 | — | — | EP | disclosed |
| EP-0617622-A1 | USE OF RENIN INHIBITORS FOR THE TREATMENT OF GLAUCOMA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-05 | — | — | EP | disclosed |
| EP-0605149-A2 | Recording sheet | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |
| EP-0604368-A1 | Anti retroviral hydrazine derivatives | CIBA-GEIGY AG (CH) | 1994-06-29 | — | — | EP | disclosed |
| EP-0600831-A1 | Phtalazinon derivatives | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |
| EP-0600830-A1 | Substituted derivatives of diaminophthalimide as protein-tyrosine kinase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |
| US-5312831-A | Immunology, anticarcinogenic agents and AIDS treatment | AMERICAN CYANAMID COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| EP-0594540-A1 | Antiretroviral acyl compounds | CIBA-GEIGY AG (CH) | 1994-04-27 | — | — | EP | disclosed |
| EP-0225634-B1 | Antibacterial compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-04-06 | — | — | EP | disclosed |
| EP-0573652-A1 | REMEDY FOR RENAL DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-12-15 | — | — | EP | disclosed |
| EP-0562832-A1 | Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0215739-B1 | SYNTHESIS OF BETA-LACTAM COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-09-01 | — | — | EP | disclosed |
| US-5234930-A | Treating psychological, cardiovascular, urogenital and respiratory disorders; diabetes, asthmas, sudden infant death syndrome | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| US-5231175-A | Halogenation of nucleosides | AMERICAN CYANAMID COMPANY (US) | 1993-07-27 | — | — | US | disclosed |
| WO-1993012796-A1 | USE OF RENIN INHIBITORS FOR THE TREATMENT OF GLAUCOMA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-08 | — | — | WO | disclosed |
| US-5223489-A | Treatment of ypertension and heart failure | UJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-29 | — | — | US | disclosed |
| US-5215997-A | Synthesis of beta-lactam compounds | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0203271-B1 | ANTIBACTERIAL COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0239853-B1 | 3,4-DISUBSTITUTED-2-AZETIDINONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-5212293-A | Process for the preparation of deoxynucleosides | AMERICAN CYANAMID COMPANY (US) | 1993-05-18 | — | — | US | disclosed |
| EP-0536401-A1 | TRICYCLO COMPOUNDS, A PROCESS FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |
| EP-0215435-B1 | 2-OXA-ISOCEPHEM COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
| EP-0516941-A1 | Pyrazolopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |
| US-5153315-A | Penicilllin deriviatives | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0160252-B1 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1992-08-26 | — | — | EP | disclosed |
| US-5142048-A | Enzyme inhibitor; carbamoyl group-containing acids | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5140030-A | Azido intermediates; carbapenicillin antibiotics | MERCK (US) | 1992-08-18 | — | — | US | disclosed |
| US-5116863-A | Antiallergens, antiinflammatory agents; asthma | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0476515-A1 | New amino acid derivatives, a process for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0324431-B1 | NEW INDOLYLPIPERIDINE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0470355-A1 | Process for the preparation of deoxynucleosides | American Cyanamid Company (US) | 1992-02-12 | — | — | EP | disclosed |
| WO-1992000313-A1 | TRICYCLO COMPOUNDS, A PROCESS FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-09 | — | — | WO | disclosed |
| US-5075437-A | 3,4-DISUBSTITUTED-2-AZETIDINONE DERIVATIVES AND PROCESSES FOR PREPARATION USING TIN ENOLATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0233154-B1 | UNSATURATED AMINO-ACIDS | CIBA-GEIGY AG (CH) | 1991-12-18 | — | — | EP | disclosed |
| EP-0433759-A1 | 4-Substituted alkyl carbapenem antibiotics | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | disclosed |
| US-5021566-A | Carbapenicillins; preservatives; antiseptics; grampositive and gram negative bacteria | MERCK & CO. INC. (US) | 1991-06-04 | — | — | US | disclosed |
| CN-1051731-A | Herbicidal compound, its preparation method and methods for using them | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-05-29 | — | — | CN | disclosed |
| US-5017703-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| US-4997936-A | Antibiotics | MERCK & CO., INC. (US) | 1991-03-05 | — | — | US | disclosed |
| US-4992542-A | Thienamycin antibiotics | MERCK & CO., INC. (US) | 1991-02-12 | — | — | US | disclosed |
| US-4973687-A | Synthesis of carbapenems using N-substituted azetidinones | BRISTOL-MYERS COMPANY (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0099329-B1 | DITHIO COMPOUNDS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE | Zyma SA (CH) | 1990-10-31 | — | — | EP | disclosed |
| US-4963530-A | Renin inhibitor peptide compounds, a process for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| US-4962196-A | (3S, 4R)-3,4-trans-disubstituted azetidin-2-one intermediates | CIBA-GEIGY CORPORATION (US) | 1990-10-09 | — | — | US | disclosed |
| US-4962100-A | 3-Condensed imidazolium-cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0164122-B1 | CEPHEM COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 1990-09-19 | — | — | EP | disclosed |
| US-4957912-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4946837-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0374098-A2 | Inhibitors of retroviral proteases | CIBA-GEIGY AG (CH) | 1990-06-20 | — | — | EP | disclosed |
| US-4935507-A | Cefdinir antibiotic | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4935432-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4933355-A | ALDOSE REDUCTASE INHIBITORS | SANKYO COMPANY LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4931591-A | Novel 5-amino-4-hydroxyvaleryl derivatives | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0166389-B1 | NEW TETRACYCLO COMPOUNDS, A PROCESS FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-23 | — | — | EP | disclosed |
| EP-0164113-B1 | 3-PYRAZOLO(1,5-A)PYRIDINIUM CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-05-16 | — | — | EP | disclosed |
| US-4921855-A | New Histidyl amino acid derivatives, and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| US-4895939-A | ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1990-01-23 | — | — | US | disclosed |
| US-4892869-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1990-01-09 | — | — | US | disclosed |
| US-4889851-A | BONE DISORDERS | FUJISAWA PHARMACEUTICAL CO, LTD. (JP) | 1989-12-26 | — | — | US | disclosed |
| US-4883800-A | DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| EP-0337819-A1 | Thiazole derivatives, their preparation and their use in the treatment of diabetes complications | Sankyo Company Limited (JP) | 1989-10-18 | — | — | EP | disclosed |
| US-4872901-A | PREFERENTIAL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0071908-B1 | 1-, AND 1,1-DISUBSTITUTED-6-SUBSTITUTED-2-CARBAMIMIDOYL-1-CARBADETHIAPEN-2-EM-3-CARBOXYLIC ACIDS, A PROCESS FOR PREPARING AND AN ANTIBIOTIC COMPOSITION CONTAINING THE SAME | MERCK & CO. INC. (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4864022-A | 3-Condensed imidazolium-cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| US-4863903-A | RENIN ENZYME INHIBITORS, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| US-4861774-A | Method of treating tumors using tetracyclo compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |
| EP-0324431-A1 | New indolylpiperidine compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-19 | — | — | EP | disclosed |
| US-RE32992-E | THERAPY FOR INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | Fujisawa Pharaceutical Co., Ltd. (JP) | 1989-07-18 | — | — | US | disclosed |
| US-4841043-A | Stereoselective synthesis of 1-β-alkyl carbapenem antibiotic intermediates | BRISTOL-MYERS COMPANY (US) | 1989-06-20 | — | — | US | disclosed |
| US-4839351-A | Antibacterial compounds, and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |
| US-4833167-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4831026-A | ANTIBIOTICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| US-4826834-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| EP-0074653-B1 | NEW CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-26 | — | — | EP | disclosed |
| US-4820817-A | Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicycl(3.2.0)-hept-2-ene-2-carboxylic acid | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| US-4818765-A | TREATING LIVER, RESPIRATORY TRACT, VASCULAR DISORDERS | CIBA-GEIGY CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |
| EP-0304019-A2 | Novel crystalline 7-(2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4-carboxylic acid (syn isomer) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-22 | — | — | EP | disclosed |
| EP-0302826-A2 | Process for the preparation of unsaturated amino acid compounds | CIBA-GEIGY AG (CH) | 1989-02-08 | — | — | EP | disclosed |
| US-4801580-A | Peptide, process for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0300189-A2 | New amino acid derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-25 | — | — | EP | disclosed |
| US-4797399-A | ANTIINFLAMMATORY AGENTS, ANTICOAGULANTS ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-10 | — | — | US | disclosed |
| US-4794109-A | 6-hydroxy-lower alkylpenem compounds, pharmaceutical preparations that contain these compounds, and the use of the latter | CIBA-GEIGY CORPORATION (US) | 1988-12-27 | — | — | US | disclosed |
| US-4788185-A | Cephalosporin compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| US-4783453-A | 2-aza-substituted 1-carbadethiapen-2-em-3-carboxylic acids | MERCK & CO., INC. (US) | 1988-11-08 | — | — | US | disclosed |
| US-4782051-A | 2-aza-substituted 1-carbadethiapen-2-em-3 carboxylic acids | MERCK & CO., INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0283970-A2 | New peptide compounds, a process for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-28 | — | — | EP | disclosed |
| US-4772683-A | SILYLATION, AZETIDONE THIOLESTERS | BRISTOL-MYERS COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| US-4769451-A | Synthesis of carbapenems using n-substituted azetidinones | BRISTOL-MYERS COMPANY (US) | 1988-09-06 | — | — | US | disclosed |
| US-4749691-A | Peptide, process for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-07 | — | — | US | disclosed |
| EP-0268990-A2 | New benzothiadiazine compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |
| US-4748162-A | 6-substituted-2-carbaminidoyl-pen-2-em-3-carboxylic acids | MERCK & CO., INC. (US) | 1988-05-31 | — | — | US | disclosed |
| US-4745188-A | ANTIBIOTICS, SULFIDING | MERCK & CO., INC. (US) | 1988-05-17 | — | — | US | disclosed |
| US-4743555-A | TETRACYCLO COMPOUND, ANTITUMOR, ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| US-4736039-A | ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| US-4734419-A | Quinazoline derivatives, compositions thereof and their use in treating diabetic complications | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4725582-A | IMMUNE RESPONSE ENHANCERS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| US-4719288-A | HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| US-4707547-A | AMINATION TO FORM ANTIBIOTIC | MERCK & CO., INC. (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0239853-A1 | 3,4-Disubstituted-2-azetidinone derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |
| EP-0235796-A2 | Dibenz [b,e] oxepin derivative and antiallergic and antiinflammatory agent | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |
| EP-0232740-A1 | N-containing fused heterocyclic compounds, processes for the preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-19 | — | — | EP | disclosed |
| EP-0233154-A2 | Unsaturated amino-acids | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | disclosed |
| EP-0110826-B1 | 6-HYDROXY LOWER ALKYL PENEM COMPOUNDS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | disclosed |
| EP-0231475-A1 | Process for preparing intermediate products and their use for preparing cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-12 | — | — | EP | disclosed |
| EP-0112283-B1 | HETEROCYCLYL-THIO COMPOUNDS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | CIBA-GEIGY AG (CH) | 1987-08-12 | — | — | EP | disclosed |
| EP-0229369-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1987-07-22 | — | — | EP | disclosed |
| US-4675317-A | PENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0225634-A2 | Antibacterial compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-06-16 | — | — | EP | disclosed |
| EP-0050334-B1 | 2-CARBAMIMIDOYL-6-SUBSTITUTED-1-CARBADETHIAPEN-2-EM-3-CARBOXYLIC ACIDS, A PROCESS FOR PREPARING AND AN ANTIBIOTIC COMPOSITION COMPRISING THE SAME | MERCK & CO. INC. (US) | 1987-06-10 | — | — | EP | disclosed |
| EP-0025842-B1 | PEPTIDES, PROCESS FOR THEIR PREPARATION, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-03 | — | — | EP | disclosed |
| EP-0073451-B1 | CARBAPENAM COMPOUND AND PROCESSES FOR THE PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-05-13 | — | — | EP | disclosed |
| US-4665065-A | 3-pyrazolo(1,5-aαpyridinium cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0220695-A1 | Herbicidal compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-05-06 | — | — | EP | disclosed |
| EP-0218999-A2 | New quinazoline derivatives, process for their production and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| US-4656165-A | Aminomethyl penem compounds | CIBA-GEIGY CORPORATION (US) | 1987-04-07 | — | — | US | disclosed |
| EP-0216385-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1987-04-01 | — | — | EP | disclosed |
| EP-0215739-A1 | Synthesis of beta-lactam compounds | CIBA-GEIGY AG (CH) | 1987-03-25 | — | — | EP | disclosed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |
| US-4650794-A | BACTERICIDAL ANTIBIOTICS | MERCK & CO., INC. (US) | 1987-03-17 | — | — | US | disclosed |
| US-4649136-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| US-4645765-A | MICROBIOCIDES, ANTITUMOR AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-02-24 | — | — | US | disclosed |
| US-4639335-A | ANHYDROPENICILLIN INTERMEDIATE | BRISTOL-MYERS COMPANY (US) | 1987-01-27 | — | — | US | disclosed |
| EP-0208889-A1 | 2-Aza-substituted 1-carbadethiapen-2-EM-3-carboxylic acids | MERCK & CO. INC. (US) | 1987-01-21 | — | — | EP | disclosed |
| EP-0203271-A2 | Antibacterial compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-12-03 | — | — | EP | disclosed |
| EP-0201459-A1 | Acylaminomethyl-penem compounds, their preparation and pharmaceutical formulations containing them | CIBA-GEIGY AG (CH) | 1986-11-12 | — | — | EP | disclosed |
| US-4616007-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1986-10-07 | — | — | US | disclosed |
| US-4613676-A | PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| WO-1986005183-A1 | ANTIBACTERIAL COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-09-12 | — | — | WO | disclosed |
| US-4596677-A | Anhydropenicillin intermediates | BRISTOL-MYERS COMPANY (US) | 1986-06-24 | — | — | US | disclosed |
| EP-0184550-A2 | 5-Amino-4-hydroxy valeryl amide derivatives | CIBA-GEIGY AG (CH) | 1986-06-11 | — | — | EP | disclosed |
| EP-0171362-A1 | Aminoalkyl penem compounds | CIBA-GEIGY AG (CH) | 1986-02-12 | — | — | EP | disclosed |
| EP-0166389-A1 | New tetracyclo compounds, a process for their production and a pharmaceutical composition containing the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | disclosed |
| EP-0164122-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0164113-A2 | 3-pyrazolo(1,5-a)pyridinium cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0160876-A1 | 1-Hetero-6-/1-Hydroxyethyl/-2-SR8-1-carbadethiapen-2-EM-3-carboxylic acids | MERCK & CO. INC. (US) | 1985-11-13 | — | — | EP | disclosed |
| EP-0160252-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-06 | — | — | EP | disclosed |
| JP-S60215688-A | PENICILLIN DERIVATIVE | TAIHO YAKUHIN KOGYO KK | 1985-10-29 | — | — | JP | disclosed |
| US-4539152-A | INTERMEDIATES FOR THIENAMYCIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| US-4539155-A | New peptide, process for preparation thereof and use thereof | FUISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| US-4530841-A | Antibiotic containing hetero ring | MERCK & CO., INC. (US) | 1985-07-23 | — | — | US | disclosed |
| US-4529597-A | Substituted penicillin antibiotic | MERCK & CO., INC. (US) | 1985-07-16 | — | — | US | disclosed |
| EP-0148128-A2 | Optically active penem compounds | CIBA-GEIGY AG (CH) | 1985-07-10 | — | — | EP | disclosed |
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |
| US-4521413-A | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-04 | — | — | US | disclosed |
| US-4515788-A | BACTERICIDAL ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-05-07 | — | — | US | disclosed |
| US-4512980-A | IMMUNOLOGICALLY EFFECTIVE | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 1985-04-23 | — | — | US | disclosed |
| EP-0134301-A1 | 6-(1'-Hydroxyethyl)-3-substituted amino-1-azabicyclo(3.2.0)-hept-2-en-7-one-2-carboxylic acid | MERCK & CO. INC. (US) | 1985-03-20 | — | — | EP | disclosed |
| EP-0037082-B1 | PROCESS FOR THE PREPARATION OF 1-CARBAPENEMS AND INTERMEDIATES VIA SILYL-SUBSTITUTED DITHIOACETALS | MERCK & CO. INC. (US) | 1985-03-20 | — | — | EP | disclosed |
| EP-0037080-B1 | 4-(3-CARBOXY-2-OXOPROPYL)-AZETIDINO-2-ONES AND PROCESS FOR THEIR PREPARATION | MERCK & CO. INC. (US) | 1985-03-13 | — | — | EP | disclosed |
| EP-0027260-B1 | PEPTIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-13 | — | — | EP | disclosed |
| US-4504584-A | PEPTIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-12 | — | — | US | disclosed |
| US-4493833-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| US-4491580-A | BACTERICIDES, BETA LACTAM ANTIBIOTICS | MERCK & CO., INC. (US) | 1985-01-01 | — | — | US | disclosed |
| EP-0035689-B1 | 4-SUBSTITUTED-2-OXOAZETIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE FOR PREPARING ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-12-19 | — | — | EP | disclosed |
| US-4487763-A | BACTERICIDE, FUNGICIDE, ANTIBODY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| EP-0125207-A1 | 2-Tetrazolylpropyl-2-penem derivatives, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1984-11-14 | — | — | EP | disclosed |
| EP-0125208-A1 | Amino-lower-alkyl-penem derivatives, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1984-11-14 | — | — | EP | disclosed |
| US-4477447-A | ANTIBIOTIC, BACTERICIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| EP-0115308-A2 | 2-Unsaturated alkylthio-pen-2-em-3-carboxylic acids and process for preparing substituted 2-thioxopenams and 2-substituted thiopenems | MERCK & CO. INC. (US) | 1984-08-08 | — | — | EP | disclosed |
| US-4464369-A | CEPHALOSPORINS, ANTIMICROBIALS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| US-4458078-A | SYNTHESIS OF OLIGOPEPTIDES | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1984-07-03 | — | — | US | disclosed |
| EP-0112283-A1 | Heterocyclyl-thio compounds, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1984-06-27 | — | — | EP | disclosed |
| EP-0110826-A1 | 6-Hydroxy lower alkyl penem compounds, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1984-06-13 | — | — | EP | disclosed |
| EP-0109362-A1 | Hetereocyclic compounds, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1984-05-23 | — | — | EP | disclosed |
| EP-0001627-B1 | 3-SUBSTITUTED-6-(1'HYDROXETHYL)-7-OXO-1-AZABICYCLO(3.2.0.)-HEPT-2-ENE-2-CARBOXYLIC ACID, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | MERCK & CO. INC. (US) | 1984-04-04 | — | — | EP | disclosed |
| US-4428960-A | AMINO ACID DERIVATIVE ANTIBIOTICS | MERCK & CO., INC. (US) | 1984-01-31 | — | — | US | disclosed |
| EP-0001628-B1 | 3-SUBSTITUTED-6-SUBSTITUTED-7-OXO-1-AZABICYCLO (3.2.0)-HEPT-2-ENE-2-CARBOXYLIC ACID, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | MERCK & CO. INC. (US) | 1984-01-18 | — | — | EP | disclosed |
| US-4424230-A | CARBAPENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0088385-A2 | 7-Acylamino-3-cephem-4-carboxylic acid derivatives, processes for the preparation of the same and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-09-14 | — | — | EP | disclosed |
| EP-0087792-A1 | 6-Substituted-2-carbamimidoyl-pen-2-em-3-carboxylic acids, process for preparing them and antibiotic compositions comprising them | MERCK & CO. INC. (US) | 1983-09-07 | — | — | EP | disclosed |
| US-4397861-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1983-08-09 | — | — | US | disclosed |
| US-4390693-A | BACTERICIDE | MERCK & CO., INC. (US) | 1983-06-28 | — | — | US | disclosed |
| EP-0082113-A1 | 2-Aminobytyl-2-penem derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| US-4388310-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1983-06-14 | — | — | US | disclosed |
| US-4383946-A | Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals | MERCK & CO., INC. (US) | 1983-05-17 | — | — | US | disclosed |
| US-4383945-A | 4-Substituted-2-oxoazetidine compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-17 | — | — | US | disclosed |
| EP-0073451-A2 | Carbapenam compound and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-03-09 | — | — | EP | disclosed |
| US-4374849-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1983-02-22 | — | — | US | disclosed |
| US-4374848-A | ADMINISTERING | MERCK & CO., INC. (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0071891-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |
| EP-0071908-A1 | 1-, and 1,1-disubstituted-6-substituted-2-carbamimidoyl-1-carbadethiapen-2-em-3-carboxylic acids, a process for preparing and an antibiotic composition containing the same | MERCK & CO. INC. (US) | 1983-02-16 | — | — | EP | disclosed |
| US-4369187-A | AMINO ACID DERIVATIVE ANTIBIOTICS | MERCK & CO., INC. (US) | 1983-01-18 | — | — | US | disclosed |
| US-4363807-A | BACTERICIDES AND USEFUL ANTIBIOTIC INTERMEDIATES | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1982-12-14 | — | — | US | disclosed |
| US-4361512-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1982-11-30 | — | — | US | disclosed |
| US-4357342-A | 1-Azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylic acid | MERCK & CO., INC. (US) | 1982-11-02 | — | — | US | disclosed |
| US-4354966-A | Peptides, process for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4347367-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4347368-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4335043-A | Substituted N-methylene derivatives of thienamycin | MERCK & CO., INC. (US) | 1982-06-15 | — | — | US | disclosed |
| EP-0050334-A1 | 2-Carbamimidoyl-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, a process for preparing and an antibiotic composition comprising the same | MERCK & CO. INC. (US) | 1982-04-28 | — | — | EP | disclosed |
| US-4318912-A | 6-(1-Hydroxyethyl)-3-substituted-1-azabicyclo(3.2.0)-hept-2-en-7-one-2-carboxylic acid | MERCK & CO., INC. (US) | 1982-03-09 | — | — | US | disclosed |
| US-4311640-A | ANTIBIOTIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-01-19 | — | — | US | disclosed |
| US-4311704-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1982-01-19 | — | — | US | disclosed |
| US-4310538-A | BACTERICIDES | MERCK & CO., INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4309438-A | BACTERICIDES | MERCK & CO., INC. (US) | 1982-01-05 | — | — | US | disclosed |
| US-4309346-A | INTERMEDIATES FOR AMINO ACID DERIVATIVE ANTIBIOTICS | MERCK & CO., INC. (US) | 1982-01-05 | — | — | US | disclosed |
| US-4304770-A | Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| EP-0038869-A1 | Process for the preparation of 1-carbapenems, and intermediates for their preparation | MERCK & CO. INC. (US) | 1981-11-04 | — | — | EP | disclosed |
| US-4298741-A | DETHIAPENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-11-03 | — | — | US | disclosed |
| EP-0037082-A1 | Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals | MERCK & CO. INC. (US) | 1981-10-07 | — | — | EP | disclosed |
| EP-0037081-A1 | Process for the preparation of 1-carbapenems and intermediates via trithioorthoacetates | MERCK & CO. INC. (US) | 1981-10-07 | — | — | EP | disclosed |
| EP-0037080-A1 | 4-(3-carboxy-2-oxopropyl)-azetidino-2-ones and process for their preparation | MERCK & CO. INC. (US) | 1981-10-07 | — | — | EP | disclosed |
| EP-0035689-A1 | 4-Substituted-2-oxoazetidine compounds, processes for their preparation, and their use for preparing antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-16 | — | — | EP | disclosed |
| US-4281002-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-07-28 | — | — | US | disclosed |
| EP-0029871-A1 | 6-Alpha-methoxy penicillin derivatives, process for their preparation and pharmaceutical compositions comprising them | BEECHAM GROUP PLC (GB) | 1981-06-10 | — | — | EP | disclosed |
| US-4269873-A | PENICILLIN DERIVATIVES | MERCK & CO., INC. (US) | 1981-05-26 | — | — | US | disclosed |
| EP-0027260-A2 | Peptides, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-22 | — | — | EP | disclosed |
| US-4260625-A | Penicillins | BEECHAM GROUP LIMITED (GB) | 1981-04-07 | — | — | US | disclosed |
| US-4260746-A | Chemical intermediates useful to prepare cephalosporins | BEECHAM GROUP LIMITED (GB) | 1981-04-07 | — | — | US | disclosed |
| EP-0025842-A2 | Peptides, process for their preparation, their pharmaceutical compositions and their intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-01 | — | — | EP | disclosed |
| US-4255423-A | BACTERICIDES | MERCK & CO., INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4252952-A | 7-(α-Substituted glycinamido)-3-substituted methyl-3-cephem-4-carboxylic acids and their derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-02-24 | — | — | US | disclosed |
| US-4246405-A | Method for preparation of β-lactam compound | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1981-01-20 | — | — | US | disclosed |
| US-4246405-A | Method for preparation of β-lactam compound | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1981-01-20 | — | — | US | disclosed |
| US-4235917-A | N-Alkyl-N-acyl derivatives of thienamycin | MERCK & CO., INC. (US) | 1980-11-25 | — | — | US | disclosed |
| US-4235920-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-11-25 | — | — | US | disclosed |
| US-4232030-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-11-04 | — | — | US | disclosed |
| EP-0017992-A1 | 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates | MERCK & CO. INC. (US) | 1980-10-29 | — | — | EP | disclosed |
| US-4226870-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4226866-A | BACTERICIDES, ACYLATION | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4224336-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4218463-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-08-19 | — | — | US | disclosed |
| US-4217453-A | BACTERICIDES, ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4209616-A | BACTERICIDES HAVING ALPHA-HYDROXIMINO- OR ALPHA-ACYLOIMINOACYLAMIDO GROUPS | GLAXO LABORATORIES LIMITED (GB) | 1980-06-24 | — | — | US | disclosed |
| US-4208330-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1980-06-17 | — | — | US | disclosed |
| EP-0010667-A1 | Cepham compounds, pharmaceutical compositions containing them and processes for the preparation thereof and of known cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-05-14 | — | — | EP | disclosed |
| US-4202973-A | Ketenimine cephalosporins | BEECHAM GROUP LIMITED (GB) | 1980-05-13 | — | — | US | disclosed |
| US-4198406-A | Carbamoyl heterocyclicthio cephalosporins and pharmaceutical compositions formulated therewith | BEECHAM GROUP LIMITED (GB) | 1980-04-15 | — | — | US | disclosed |
| US-4196211-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1980-04-01 | — | — | US | disclosed |
| US-4194047-A | Substituted N-methylene derivatives of thienamycin | MERCK & CO., INC. (US) | 1980-03-18 | — | — | US | disclosed |
| US-4185014-A | Kentenimine intermediates for 6α-methoxy-α-carboxy penicillins | BEECHAM GROUP LIMITED (GB) | 1980-01-22 | — | — | US | disclosed |
| US-4182710-A | Ketenimine intermediates for 6α-methoxy-α-carboxy penicillins | BEECHAM GROUP LIMITED (GB) | 1980-01-08 | — | — | US | disclosed |
| US-4181733-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | disclosed |
| US-4178445-A | 7-(α-Substituted glycinamido)-3-substituted methyl-3-cephem-4-carboxylic acids and their derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-12-11 | — | — | US | disclosed |
| US-4172144-A | Schiff's base derivatives of thienamycin | MERCK & CO., INC. (US) | 1979-10-23 | — | — | US | disclosed |
| EP-0001628-A1 | 3-Substituted-6-substituted-7-oxo-1-azabicyclo (3.2.0)-hept-2-ene-2-carboxylic acid, its preparation and pharmaceutical compositions containing it | MERCK & CO. INC. (US) | 1979-05-02 | — | — | EP | disclosed |
| EP-0001627-A1 | 3-Substituted-6-(1'hydroxethyl)-7-oxo-1-azabicyclo(3.2.0.)-hept-2-ene-2-carboxylic acid, its preparation and pharmaceutical compositions containing it | MERCK & CO. INC. (US) | 1979-05-02 | — | — | EP | disclosed |
| US-4150145-A | ANTIBIOTIC, BACTERICIDES | MERCK & CO., INC. (US) | 1979-04-17 | — | — | US | disclosed |
| EP-0001265-A1 | O-, N- and carboxyl derivatives of thienamycin sulfoxide and sulfone, their preparation and pharmaceuticals containing said compounds | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |
| EP-0001264-A1 | Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |
| US-4115566-A | 7α Ureido cephem-4-carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4110534-A | PROCESS FOR THE PREPARATION OF 3-VINYL AND SUBSTITUTED VINYL CEPHALOSPORINS | GLAXO LABORATORIES LIMITED (GB) | 1978-08-29 | — | — | US | disclosed |
| US-4107431-A | ANTIBIOTICS | GLAXO LABORATORIES LIMITED (GB) | 1978-08-15 | — | — | US | disclosed |
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4078068-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4078067-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4076826-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4064344-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1977-12-20 | — | — | US | disclosed |
| US-4039536-A | 7-(α-SUBSTITUTED GLYCINAMIDO)-3-SUBSTITUTED METHYL-3-CEPHEM-4-CARBOXYLIC ACIDS AND THEIR DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-08-02 | — | — | US | disclosed |
| US-3996208-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1976-12-07 | — | — | US | disclosed |
| US-3974151-A | Cephalosporin compounds | MERCK & CO., INC. (US) | 1976-08-10 | — | — | US | disclosed |
| US-3954802-A | Substituted-ureido derivatives of penam 3-carboxylic acid and cephem 4-carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
| US-3936443-A | Penicillin antibiotics | GLAXO LABORATORIES LIMITED (EN) | 1976-02-03 | — | — | US | disclosed |
| JP-H00912546-A | — | — | 0001-01-01 | — | — | JP | disclosed |
| JP-H00912546-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037786-A1 | Cephem compounds | CEP170, ABCB11, SLC7A1 | KIF11 2448/4885MAPK1 3966/4885KCNN4 3757/4885 |
| US-20060004039-A1 | Aryl-substituted benzimidazole and imidazopyridine ethers | WEE1, CDKN1A, DDB1 | KIF11 4161/4885MAPK1 301/4885KCNN4 3497/4885 |
| US-20040132994-A1 | Cephem compounds | CEP170, ABCB11, RCC2 | KIF11 2780/4885MAPK1 3464/4885KCNN4 3863/4885 |
| US-20190047998-A1 | NITROGEN-CONTAINING HETEROCYCLE AND CARBOCYCLE DERIVATIVES HAVING TRKA INHIBITORY ACTIVITY | NTRK2, NTRK3, NTRK1 | KIF11 2701/4885MAPK1 429/4885KCNN4 690/4885 |
| US-20180079727-A1 | 9-MEMBERED FUSED RING DERIVATIVE | ACSS2, AGTR2, ACSL3 | KIF11 1922/4885MAPK1 1663/4885KCNN4 966/4885 |
| US-20100274005-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS | NOD2, BAK1, CASP3 | KIF11 3943/4885MAPK1 1955/4885KCNN4 3324/4885 |
| US-20050020565-A1 | Pyrazole compound; gastrointestinal disorders; central nervous system disorders | CCKAR, CCKBR, NPY1R | KIF11 2563/4885MAPK1 305/4885KCNN4 718/4885 |
| US-20100324338-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION | H1-0, H1-5, ADH5 | KIF11 3667/4885MAPK1 1954/4885KCNN4 2962/4885 |
| US-20140275074-A1 | HETEROCYCLIC DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONIST ACTIVITY | PTGDR, PTGDR2, PTGER4 | KIF11 4496/4885MAPK1 1480/4885KCNN4 346/4885 |
| US-20080132511-A1 | Cholecystokinin (CCK) receptor ligands; antagonists; 3-(5-Bromo-thiophen-2-yl)-2-[4-chloro-2-(quinoxaline-5-sulfonylamino)-benzoylamino]-propionic acid methy; pain, drug dependence, anxiety, panic attack, schizophrenia, pancreatic disorders, secretory disorders, ulcers, cancers; improved pharmacokinetics | CCKAR, CCKBR, GRPR | KIF11 3886/4885MAPK1 745/4885KCNN4 1379/4885 |
| US-10150728-B2 | Alkylene derivatives | ACSS2, ACACB, CES2 | KIF11 3539/4885MAPK1 2456/4885KCNN4 3128/4885 |
| US-20200055873-A1 | NITROGEN-CONTAINING TRICYCLIC DERIVATIVES HAVING HIV REPLICATION INHIBITORY ACTIVITY | NR4A3, CCR3, NCOA3 | KIF11 4634/4885MAPK1 2406/4885KCNN4 3070/4885 |
| US-20040077628-A1 | Melanin-concentrating hormone antagonist | MCHR1, MC1R, MCHR2 | KIF11 3314/4885MAPK1 817/4885KCNN4 2386/4885 |
| US-20060287292-A1 | NAPHTHYRIDINE COMPOUNDS | HRH3, HRH4, HRH1 | KIF11 4577/4885MAPK1 3446/4885KCNN4 3039/4885 |
| US-20060223826-A1 | Indole derivatives as somatostatin agonists or antagonists | SSTR1, SSTR3, NPY1R | KIF11 3457/4885MAPK1 1374/4885KCNN4 595/4885 |
| US-10640495-B2 | Heterocycle derivatives having TrkA inhibitory activity | NTRK2, NR5A2, NTRK1 | KIF11 2109/4885MAPK1 438/4885KCNN4 1665/4885 |
| US-20060014817-A1 | CCK-1 receptor modulators | CCKAR, CCKBR, GIPR | KIF11 3368/4885MAPK1 274/4885KCNN4 2273/4885 |
| US-20040092436-A1 | Immunosuppressive imidazole derivatives and their combination preparations with tacrolimus of cyclosporins | IL2, ICOS, NOS2 | KIF11 4697/4885MAPK1 1709/4885KCNN4 1738/4885 |
| US-20150361093-A1 | HIV REPLICATION INHIBITOR | RTF2, REV1, PCNA | KIF11 4256/4885MAPK1 2097/4885KCNN4 4691/4885 |
| US-20160318916-A1 | NITROGEN-CONTAINING SIX-MEMBERED CYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NGLY1, C1R | KIF11 1953/4885MAPK1 1919/4885KCNN4 407/4885 |
| US-20120136176-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME | HMOX1, HIRA, HRH1 | KIF11 4244/4885MAPK1 2175/4885KCNN4 4410/4885 |
| US-20180201607-A1 | HETEROCYCLE DERIVATIVES HAVING TRKA INHIBITORY ACTIVITY | NTRK2, NR5A2, NTRK1 | KIF11 2109/4885MAPK1 438/4885KCNN4 1665/4885 |
| US-20060293316-A1 | HEXAHYDRO-PYRROLO-ISOQUINOLINE COMPOUNDS | HRH3, HRH1, HRH4 | KIF11 4018/4885MAPK1 3444/4885KCNN4 2396/4885 |
| US-20200354358-A1 | NITROGEN-CONTAINING HETEROCYCLE AND CARBOCYCLE DERIVATIVES HAVING TRKA INHIBITORY ACTIVITY | NTRK2, NTRK3, NTRK1 | KIF11 2701/4885MAPK1 429/4885KCNN4 690/4885 |
| US-20100240648-A1 | HEXAHYDRO-PYRROLO-ISOQUINOLINE COMPOUNDS | HRH3, HRH1, HRH4 | KIF11 4018/4885MAPK1 3444/4885KCNN4 2396/4885 |
| US-20220235047-A1 | A MEDICAMENT FOR TREATING MYCOBACTERIAL INFECTION CHARACTERIZED BY COMBINING A CYTOCHROME bc1 INHIBITOR WITH CLARITHROMYCIN OR AZITHROMYCIN AND CLOFAZIMINE | CYC1, MT-CO1, ABCB11 | KIF11 2552/4885MAPK1 338/4885KCNN4 3323/4885 |
| US-20180162876-A1 | NITROGEN-CONTAINING TRICYCLIC DERIVATIVES HAVING HIV REPLICATION INHIBITORY ACTIVITY | NR4A3, CCR3, NCOA3 | KIF11 4634/4885MAPK1 2406/4885KCNN4 3070/4885 |
| US-20090143591-A1 | SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES | ABL1, NOS2, FLT3 | KIF11 540/4885MAPK1 2727/4885KCNN4 2124/4885 |
| US-10160727-B2 | Heterocycle and carbocycle derivatives having TrkA inhibitory activity | NR5A2, NPY5R, MC5R | KIF11 2254/4885MAPK1 824/4885KCNN4 1490/4885 |
| US-20040067983-A1 | CCK-1 receptor modulators | CCKAR, CCKBR, GIPR | KIF11 3368/4885MAPK1 274/4885KCNN4 2273/4885 |
| US-20060223810-A1 | Bicyclic pyrazole compounds as antibacterial agents | NOD2, BAK1, CASP3 | KIF11 3943/4885MAPK1 1955/4885KCNN4 3324/4885 |
| US-20170066759-A1 | AROMATIC 5-MEMBERED HETEROCYCLIC DERIVATIVE HAVING TRPV4-INHIBITING ACTIVITY | TRPV4, TRPC4, TRPV2 | KIF11 3225/4885MAPK1 1592/4885KCNN4 6/4885 |
| US-20060194837-A1 | Tetrahydroisoquinoline compounds | HRH3, HRH4, HRH1 | KIF11 4496/4885MAPK1 3782/4885KCNN4 3267/4885 |
| US-20050049241-A1 | Pyridyl piperazinyl ureas | VIPR1, UTS2R, GPR17 | KIF11 4617/4885MAPK1 851/4885KCNN4 1068/4885 |
| US-20060223792-A1 | Phenyl and pyridyl LTA4H modulators | LTA4H, LTB4R, LTC4S | KIF11 4866/4885MAPK1 1801/4885KCNN4 1925/4885 |
| US-20050130941-A1 | Methods of treating alzheimer's disease | BACE1, PSEN1, BACE2 | KIF11 3890/4885MAPK1 4408/4885KCNN4 3093/4885 |
| US-20170073337-A1 | DIHYDROTHIAZINE AND DIHYDROOXAZINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | BACE1, BACE2, APP | KIF11 4150/4885MAPK1 2923/4885KCNN4 2937/4885 |
| US-20030207858-A1 | Selective modulators of the nicotinic acetylcholine receptor useful in the treatment of pain, Alzheimer's disease, memory loss or dementia or loss of motor function. | CHRM1, CHRM5, CHRM2 | KIF11 2289/4885MAPK1 858/4885KCNN4 455/4885 |
| US-10532985-B2 | Heterocycle and carbocycle derivatives having TRKA inhibitory activity | NR5A2, NPY5R, MC5R | KIF11 2254/4885MAPK1 824/4885KCNN4 1490/4885 |
| US-20070173512-A1 | Imidazole compounds | HRH4, HRH3, HRH2 | KIF11 3972/4885MAPK1 3308/4885KCNN4 3499/4885 |
| US-20050096306-A1 | Cephem compounds | CEP170, ASS1, C1S | KIF11 3237/4885MAPK1 3747/4885KCNN4 2885/4885 |
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | ACSS2, ACACB, ACAT2 | KIF11 2653/4885MAPK1 2691/4885KCNN4 3196/4885 |
| US-20100274004-A1 | BICYCLIC PIRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS | PIR, BAK1, TMBIM6 | KIF11 2992/4885MAPK1 3065/4885KCNN4 3597/4885 |
| US-20100280240-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS | NOD2, BAK1, CASP3 | KIF11 3943/4885MAPK1 1955/4885KCNN4 3324/4885 |
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | CPN1, HAT1, PRSS1 | KIF11 4397/4885MAPK1 2703/4885KCNN4 3633/4885 |
| US-20130217895-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME | HMOX1, NQO1, CBR3 | KIF11 4205/4885MAPK1 2082/4885KCNN4 4080/4885 |
| US-20050250948-A1 | Scalable synthesis of imidazole derivatives | ABL1, NOS2, FLT3 | KIF11 540/4885MAPK1 2727/4885KCNN4 2124/4885 |
| US-20060128690-A1 | Amine derivative | MC1R, MC2R, MC4R | KIF11 3221/4885MAPK1 766/4885KCNN4 2553/4885 |
| US-20030158177-A1 | Treating or preventing obesity | MCHR1, MC1R, NPY1R | KIF11 4001/4885MAPK1 740/4885KCNN4 2679/4885 |
| US-10870661-B2 | Nitrogen-containing tricyclic derivatives having HIV replication inhibitory activity | NR4A3, CCR3, NCOA3 | KIF11 4634/4885MAPK1 2406/4885KCNN4 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.