Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 known ✓ | P45452 | 1/20 | 0.39 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.35 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384819 | 0.97 | DNM1 (0.45) | DNM1MMP13TSHRALDH1A1TDP1 | |
| Iodide SCHEMBL6383667 | 0.93 | DNM1 (0.43) | DNM1MMP13TSHRALDH1A1TDP1 | |
| SCHEMBL10942066 | 0.93 | DNM1 (0.43) | DNM1MMP13TSHRALDH1A1TDP1 | |
| SCHEMBL10941450 | 0.93 | DNM1 (0.43) | DNM1MMP13TSHRALDH1A1TDP1 | |
| SCHEMBL10947406 | 0.93 | DNM1 (0.43) | DNM1MMP13TSHRALDH1A1TDP1 | |
| Water SCHEMBL7551987 | 0.93 | DNM1 (0.43) | DNM1MMP13TSHRALDH1A1TDP1 | |
| Bromide SCHEMBL3385366 | 0.93 | DNM1 (0.43) | DNM1MMP13TSHRALDH1A1TDP1 | |
| SCHEMBL14491205 | 0.90 | DNM1 (0.48) | DNM1MMP13TSHRLMNAFDPS | |
| SCHEMBL1904191 | 0.90 | DNM1 (0.48) | DNM1MMP13TSHRLMNAFDPS | |
| SCHEMBL3177291 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015442-A1 | SULFONE COMPOUND AND METHOD FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20110015441-A1 | SULFONE COMPOUND AND PROCESS FOR PRODUCING CAROTENOID USING THE SAME COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-20 | — | — | US | disclosed |
| EP-1477477-B1 | PROCESS FOR PREPARATION OF CAROTENOIDS | SUMITOMO CHEMICAL CO (JP) | 2010-12-22 | — | — | EP | disclosed |
| EP-2261204-A1 | SULFONE COMPOUND AND METHOD FOR PRODUCING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-12-15 | — | — | EP | disclosed |
| EP-2253613-A1 | SULFONE COMPOUND AND CAROTENOID MANUFACTURING METHOD USING SAID COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2010-11-24 | — | — | EP | disclosed |
| EP-1477477-A1 | PROCESS FOR PREPARATION OF CAROTENOIDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-20040204612-A1 | Process for preparation of carotenoids | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-10-14 | — | — | US | disclosed |
| EP-1199303-B1 | Process for producing retinol and intermediate compounds for producing the same | SUMITOMO CHEMICAL CO (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6784321-B2 | 1-((2-ARYLSULFONYL)(3-METHYL)(5-OXY)PENT-3-ENE)-2,6,6-TRIMETHY LCYCLOHEX-1-ENE DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-08-31 | — | — | US | disclosed |
| US-20040082814-A1 | Process for producing retinol and intermediate compounds for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-04-29 | — | — | US | disclosed |
| EP-1199303-A1 | Process for producing retinol and intermediate compounds for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-04-24 | — | — | EP | disclosed |
| US-6348622-B1 | CHEMICAL INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| US-6297402-B1 | CHEMICAL INTERMEDIATES FOR ASTAXANTHINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-10-02 | — | — | US | disclosed |
| US-20010025127-A1 | Dihalo-compound and process for producing vitamin A derivative | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-09-27 | — | — | US | disclosed |
| EP-1120398-A2 | Dihalo-compound and process for producing vitamin A derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-01 | — | — | EP | disclosed |
| US-6211411-B1 | SULFONE ALDEHYDE DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-03 | — | — | US | disclosed |
| US-6172265-B1 | DRUG; FOOD OR FEED ADJUVANT; CHEMICAL INTERMEDIATE FOR CANTHAXANTHIN | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| US-6160181-A | Tetraene derivative and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0983998-A1 | Tetraene derivative and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0900785-A2 | Vitamin A related compounds and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204612-A1 | Process for preparation of carotenoids | SCLY, RPS4Y1, ENY2 | MMP13 3291/4885OPRM1 2190/4885CA2 4071/4885 |
| US-20110015442-A1 | SULFONE COMPOUND AND METHOD FOR PRODUCING THE SAME | MSRB3, HCN4, SULT1E1 | MMP13 3506/4885OPRM1 284/4885CA2 151/4885 |
| US-20040082814-A1 | Process for producing retinol and intermediate compounds for producing the same | ADH4, ADH1B, ADH7 | MMP13 2456/4885OPRM1 2429/4885CA2 4542/4885 |
| US-20010025127-A1 | Dihalo-compound and process for producing vitamin A derivative | CYP2R1, CYP24A1, VDR | MMP13 3974/4885OPRM1 3223/4885CA2 2226/4885 |
| US-20110015441-A1 | SULFONE COMPOUND AND PROCESS FOR PRODUCING CAROTENOID USING THE SAME COMPOUND | SCLY, ENY2, ZYX | MMP13 1971/4885OPRM1 2747/4885CA2 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.