Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR known ✓ | P30968 | 1/20 | 0.37 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.33 |
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3940414 | 1.00 | PLG (0.44) | PLGPLATLMNACYP2D6TDP1 | |
| SCHEMBL3220801 | 0.99 | PLG (0.45) | PLGPLATLMNACYP2D6TDP1 | |
| SCHEMBL2205126 | 0.99 | PLG (0.45) | PLGPLATLMNACYP2D6TDP1 | |
| Hydrochloric Acid SCHEMBL23698037 | 0.87 | CYP2D6 (0.50) | CYP2D6TDP1EPHX1CYP3A4TSHR | |
| SCHEMBL16194235 | 0.86 | CYP2D6 (0.38) | PLGPLATLMNACYP2D6TDP1 | |
| SCHEMBL3680694 | 0.76 | ALDH1A1 (0.39) | GNRHRCYP3A4TSHRKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8117093 | 0.72 | PLG (0.55) | PLGPLATLMNACYP2D6TDP1 | |
| SCHEMBL8601731 | 0.71 | PLG (0.57) | PLGPLATLMNACYP2D6TDP1 | |
| Hydrochloric Acid SCHEMBL2471021 | 0.70 | LMNA (0.38) | PLGPLATLMNATSHRSMN1; SMN2 | |
| SCHEMBL8596242 | 0.70 | TDP1 (0.76) | PLGPLATLMNACYP2D6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115066227-B | Oil-in-water type emulsified cosmetic | 株式会社高丝 | 2025-03-07 | — | — | CN | disclosed |
| WO-2024203441-A1 | POWDERY SOLID COSMETIC | 株式会社 資生堂 | 2024-10-03 | — | — | WO | disclosed |
| WO-2024142969-A1 | WATER-IN-OIL EMULSION COMPOSITION | 株式会社 資生堂 | 2024-07-04 | — | — | WO | disclosed |
| WO-2024142892-A1 | W/O/W EMULSIFIED COMPOSITION | 株式会社 資生堂 | 2024-07-04 | — | — | WO | disclosed |
| EP-3597174-B1 | TWO-COMPONENT COSMETIC | SHISEIDO CO LTD (JP) | 2024-04-17 | — | — | EP | disclosed |
| US-11819564-B2 | Composition comprising polyion complex particle and oil | L'OREAL (FR) | 2023-11-21 | — | — | US | disclosed |
| US-11730682-B2 | Self-standing cosmetic sheet | L'OREAL (FR) | 2023-08-22 | — | — | US | disclosed |
| CN-116437972-A | Oil-in-water emulsion compositions comprising platinum catalysts and methods of use thereof | 株式会社资生堂 | 2023-07-14 | — | — | CN | disclosed |
| US-11642297-B2 | Combination of polyion complex particle and hydrophilic or water-soluble UV filter | L'OREAL (FR) | 2023-05-09 | — | — | US | disclosed |
| CN-111329788-B | Copolymer | 宝丽化学工业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| US-20100010241-A1 | Cosmetics | SHISEIDO COMPANY LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| EP-2123249-A1 | OIL SOLUTION, AND LUBRICANT, MOISTURE-RETAINING AGENT AND PREPARATION FOR EXTERNAL APPLICATION CONTAINING THE SAME | Kokyu Alcohol Kogyo Co., Ltd. (JP) | 2009-11-25 | — | — | EP | disclosed |
| US-20090263339-A1 | AGENT FOR EXTERNAL APPLICATION TO THE SKIN | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKY (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-2103300-A1 | COSMETIC | Shiseido Company, Limited (JP) | 2009-09-23 | — | — | EP | disclosed |
| US-20080200544-A1 | superior water and/or oil solubility as well as suppressed stickiness when applied to skin; esters of a specific dibasic acid (e.g malic, succinic, tartaric or adipic acids) and a poly (or mono) ethylene glycol monoether; cosmetics, shampoo, hair mists, moisturizing lotions, paints, ink, lubricants | KOKYU ALCOHOL KOGYO CO., LTD. (JP) | 2008-08-21 | — | — | US | disclosed |
| US-20080124367-A1 | Oil Based Composition For External Use On Skin For Enhancing Percutaneous Absorption | SHISEIDO COMPANY, LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| EP-1894558-A1 | AGENT FOR EXTERNAL APPLICATION TO THE SKIN | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2008-03-05 | — | — | EP | disclosed |
| US-20070269470-A1 | Oil base and external preparation containing same | KOKYU ALCOHOL KOGYO CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| EP-1839647-A1 | OILY SKIN COMPOSITION FOR EXTERNAL USE FOR ACCELERATING PERCUTANEOUS ABSORPTION | SHISEIDO COMPANY, LTD. (JP) | 2007-10-03 | — | — | EP | disclosed |
| EP-1158021-A1 | MICROGELS AND EXTERNAL PREPARATIONS CONTAINING THE SAME | SHISEIDO COMPANY LIMITED (JP) | 2001-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11642297-B2 | Combination of polyion complex particle and hydrophilic or water-soluble UV filter | KRT18, CUTA, PUF60 | GNRHR 3822/4885CA2 3519/4885MMP1 2987/4885 |
| US-20100010241-A1 | Cosmetics | CENPE, H1-0, PROC | GNRHR 4269/4885CA2 449/4885MMP1 2137/4885 |
| US-11730682-B2 | Self-standing cosmetic sheet | CUTA, DSG1, SUCLG1 | GNRHR 4456/4885CA2 4204/4885MMP1 769/4885 |
| US-20080200544-A1 | superior water and/or oil solubility as well as suppressed stickiness when applied to skin; esters of a specific dibasic acid (e.g malic, succinic, tartaric or adipic acids) and a poly (or mono) ethylene glycol monoether; cosmetics, shampoo, hair mists, moisturizing lotions, paints, ink, lubricants | ME1, ME2, MSMO1 | GNRHR 1657/4885CA2 1807/4885MMP1 1185/4885 |
| US-11819564-B2 | Composition comprising polyion complex particle and oil | PIK3CA, PTEN, PIK3CG | GNRHR 4169/4885CA2 715/4885MMP1 3457/4885 |
| US-20070269470-A1 | Oil base and external preparation containing same | ALOX12, SOAT1, MED12 | GNRHR 2366/4885CA2 2452/4885MMP1 2883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.