Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL7540084 | 1.00 | TSHR (0.56) | TSHRALDH1A1THRBTDP1SMN1; SMN2 | |
| Hexane SCHEMBL7995860 | 1.00 | TSHR (0.56) | TSHRALDH1A1THRBTDP1SMN1; SMN2 | |
| Hexane SCHEMBL9430852 | 1.00 | TSHR (0.56) | TSHRALDH1A1THRBTDP1SMN1; SMN2 | |
| Hexane SCHEMBL2394206 | 0.96 | TSHR (0.53) | TSHRALDH1A1THRBTDP1SMN1; SMN2 | |
| Hexane SCHEMBL27549779 | 0.96 | TSHR (0.53) | TSHRALDH1A1THRBTDP1SMN1; SMN2 | |
| Heptane SCHEMBL3404480 | 0.96 | TSHR (0.62) | TSHRALDH1A1THRBTDP1SMN1; SMN2 | |
| Heptane SCHEMBL10683139 | 0.93 | TSHR (0.59) | TSHRALDH1A1THRBTDP1SMN1; SMN2 | |
| Hexane SCHEMBL9425560 | 0.93 | SMN1; SMN2 (0.53) | TSHRALDH1A1THRBTDP1SMN1; SMN2 | |
| Pentane SCHEMBL2454203 | 0.92 | TSHR (0.58) | TSHRALDH1A1THRBTDP1SMN1; SMN2 | |
| Hexane SCHEMBL7176518 | 0.91 | TSHR (0.64) | TSHRALDH1A1THRBTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 554 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698402-B | Separation method of ouabain and 12-epi-ouabain | 川北医学院 | 2023-05-30 | — | — | CN | claimed |
| CN-109580810-B | Method for determining hydroxyl polybrominated diphenyl ethers in plant sample | 西北大学 | 2020-10-20 | — | — | CN | claimed |
| CN-110698402-A | Method for separating ouwu alkali and 12-epi-ouwu alkali | 川北医学院 | 2020-01-17 | — | — | CN | claimed |
| CN-109580810-A | The method for measuring hydroxyl polybrominated diphenyl ethers in plant sample | 西北大学 | 2019-04-05 | — | — | CN | claimed |
| CN-105486763-A | Quality detection method for Kunling Wan and application thereof | TASLY PHARMACEUTICAL GROUP CO | 2016-04-13 | — | — | CN | claimed |
| CN-102807955-B | Method for preparing anti-tumor compound Rasfonin and special strain of method | INST PHARM & TOXICOLOGY AMMS | 2013-07-31 | — | — | CN | claimed |
| CN-102807955-A | Method for preparing anti-tumor compound Rasfonin and special strain of method | INST PHARM & TOXICOLOGY AMMS | 2012-12-05 | — | — | CN | claimed |
| CN-102795971-A | Method for extracting high-purity antitumor substance oxyresveratrol from chinaroot greenbrier | YANTAI BOHAI PHARMACEUTICALS GROUP CO LTD | 2012-11-28 | — | — | CN | claimed |
| CN-102675070-A | Preparation method of agroskerin | NANJING ZELANG MEDICAL TECH CO | 2012-09-19 | — | — | CN | claimed |
| CN-101703656-B | Method for detecting quality of capsules for regulating menstruation and activating blood | GUIYANG XIN TIAN PHARMACEUTICAL CO LTD | 2012-03-21 | — | — | CN | claimed |
| CN-101890077-A | Preparation method and quality detection method of rhizoma corydalis pain relieving soft capsules | JIANGSU KANION PHARMACEUTICAL | 2010-11-24 | — | — | CN | claimed |
| CN-101703656-A | Method for detecting quality of capsules for regulating menstruation and activating blood | GUIYANG XIN TIAN PHARMACEUTICA | 2010-05-12 | — | — | CN | claimed |
| CN-101700287-A | Traditional Chinese medicine composition for treating gastropathy and preparation method and quality control method thereof | EASTANTAI PHARMACEUTICAL CO LT | 2010-05-05 | — | — | CN | claimed |
| US-20090226546-A1 | COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS | D-HERB LTD. (IL) | 2009-09-10 | — | — | US | claimed |
| US-20070154572-A1 | Compositions derived from portulaca oleracea l. and methods of using same for modulating blood glucose levels | D-HERB LTD. (IL) | 2007-07-05 | — | — | US | claimed |
| US-20040033273-A1 | Withasol and methods of use | AYURCORE, INC. | 2004-02-19 | — | — | US | claimed |
| WO-2002079748-A2 | WITHASOL AND METHODS OF USE | BIO-VED PHARMACEUTICALS, INC. (US) | 2002-10-10 | — | — | WO | claimed |
| US-4978744-A | Synthesis of dolastatin 10 | ARIZONA BOARD OF REGENTS (US) | 1990-12-18 | — | — | US | claimed |
| US-4160083-A | Process for the separation of antibiotic macrolides | MERCK & CO., INC. (US) | 1979-07-03 | — | — | US | claimed |
| CN-113166140-B | CDK8/19 inhibitors | 拜奥卡德联合股份公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2024097944-A2 | TRYPTAMINE DERIVATIVES | CAAMTECH, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2023250465-A2 | TRYPTAMINE DERIVATIVES | CAAMTECH, INC. (US) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023237795-A1 | USE OF THE (+)-ELATOL COMPOUND FOR TREATING OR PREVENTING A NAEGLERIA FOWLERI INFECTION | UNIVERSIDAD DE LA LAGUNA (ES) | 2023-12-14 | — | — | WO | disclosed |
| US-11840531-B2 | CDK8/19 inhibitors | JOINT STOCK COMPANY "BIOCAD" (RU) | 2023-12-12 | — | — | US | disclosed |
| WO-2023225678-A2 | TRYPTAMINE DERIVATIVES | CAAMTECH, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| US-20230321130-A1 | Senolytic Compositions and Uses Thereof | Rubedo Life Sciences, Inc. | 2023-10-12 | — | — | US | disclosed |
| US-11753428-B2 | Binuclear iron-fused porphyrin | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-09-12 | — | — | US | disclosed |
| CN-110698402-B | Separation method of ouabain and 12-epi-ouabain | 川北医学院 | 2023-05-30 | — | — | CN | disclosed |
| CN-110698402-B | Separation method of ouabain and 12-epi-ouabain | 川北医学院 | 2023-05-30 | — | — | CN | disclosed |
| US-20230088889-A1 | BINUCLEAR IRON-FUSED PORPHYRIN | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2023-03-23 | — | — | US | disclosed |
| CN-115575548-A | Method for extracting and detecting phospholipid in mammal milk and dairy products | 内蒙古蒙牛乳业（集团）股份有限公司 | 2023-01-06 | — | — | CN | disclosed |
| US-20210299154-A1 | Senolytic Compositions And Uses Thereof | Rubedo Life Sciences, Inc. | 2021-09-30 | — | — | US | disclosed |
| US-20210246138-A1 | CDK8/19 INHIBITORS | JOINT STOCK COMPANY "BIOCAD" (RU) | 2021-08-12 | — | — | US | disclosed |
| CN-113166140-A | CDK8/19 inhibitors | 拜奥卡德联合股份公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2021133362-A1 | USE OF SPECIFIC FRACTIONS OBTAINED FROM THE CLADODES OF OPUNTIA FICUS-INDICA PLANT FOR TREATING CANCER | ISTANBUL MEDIPOL UNIVERSITESI (TR) | 2021-07-01 | — | — | WO | disclosed |
| EP-3831829-A1 | CDK8/19 INHIBITORS | Joint Stock Company "Biocad" (RU) | 2021-06-09 | — | — | EP | disclosed |
| US-11026963-B2 | Senolytic compositions and uses thereof | Rubedo Life Sciences, Inc. (US) | 2021-06-08 | — | — | US | disclosed |
| CN-112469697-A | Anti-aging composition and application thereof | 鲁贝多生命科学公司 | 2021-03-09 | — | — | CN | disclosed |
| EP-3062784-B1 | ANTIMICROBIAL COMPOUNDS | AKTHELIA PHARMACEUTICALS (IS) | 2020-12-23 | — | — | EP | disclosed |
| CN-109580810-B | Method for determining hydroxyl polybrominated diphenyl ethers in plant sample | 西北大学 | 2020-10-20 | — | — | CN | disclosed |
| US-10746639-B2 | Method and device to extract an analyte from a sample with gas assistance | DIONEX CORPORATION (US) | 2020-08-18 | — | — | US | disclosed |
| US-10571374-B2 | Method and device to extract an analyte from a sample with gas assistance | DIONEX CORPORATION (US) | 2020-02-25 | — | — | US | disclosed |
| WO-2020027704-A1 | CDK8/19 INHIBITORS | ЗАКРЫТОЕ АКЦИОНЕРНОЕ ОБЩЕСТВО "БИОКАД" | 2020-02-06 | — | — | WO | disclosed |
| CN-110698402-A | Method for separating ouwu alkali and 12-epi-ouwu alkali | 川北医学院 | 2020-01-17 | — | — | CN | disclosed |
| CN-110698402-A | Method for separating ouwu alkali and 12-epi-ouwu alkali | 川北医学院 | 2020-01-17 | — | — | CN | disclosed |
| US-20200016185-A1 | SENOLYTIC COMPOSITIONS AND USES THEREOF | Rubedo Life Sciences, Inc. | 2020-01-16 | — | — | US | disclosed |
| CN-109580810-A | The method for measuring hydroxyl polybrominated diphenyl ethers in plant sample | 西北大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-109342355-A | The construction method of neck waist recovering capsule near-infrared quantitative calibration models and the detection method of neck waist recovering capsule | 吉林省现代中药工程研究中心有限公司 | 2019-02-15 | — | — | CN | disclosed |
| US-9957226-B2 | Antimicrobial compounds | AKTHELIA PHARMACEUTICALS (IS) | 2018-05-01 | — | — | US | disclosed |
| CN-104844555-B | A kind of alkaloid compound, its pharmaceutical composition, preparation method and the usage | 中国人民解放军军事医学科学院毒物药物研究所 | 2018-03-13 | — | — | CN | disclosed |
| EP-2763982-B1 | SUBSTITUTED BENZYLINDAZOLES FOR USE AS BUB1 KINASE INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES. | Bayer Pharma AG (DE) | 2018-01-10 | — | — | EP | disclosed |
| US-9725419-B2 | Cycloalkyl substituted pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| EP-3194379-A1 | BENZYL SUBSTITUTED INDAZOLES AS BUB1 INHIBITORS | Bayer Pharma Aktiengesellschaft (DE) | 2017-07-26 | — | — | EP | disclosed |
| US-20170007625-A1 | NOVEL FORMULATIONS TO INHIBIT CYCLOOXYGENASE AND PRO-INFLAMMATORY CYTOKINE MEDIATED DISEASES | Bioved Pharmaceuticals, Inc. (US) | 2017-01-12 | — | — | US | disclosed |
| US-9512315-B2 | Quenching dye for labeling biomolecules and method for preparing the same | DKC CORPORATION (KR) | 2016-12-06 | — | — | US | disclosed |
| US-20160349159-A1 | METHOD AND DEVICE TO EXTRACT AN ANALYTE FROM A SAMPLE WITH GAS ASSISTANCE | DIONEX CORPORATION | 2016-12-01 | — | — | US | disclosed |
| US-20160349158-A1 | METHOD AND DEVICE TO EXTRACT AN ANALYTE FROM A SAMPLE WITH GAS ASSISTANCE | DIONEX CORPORATION | 2016-12-01 | — | — | US | disclosed |
| US-20160266130-A1 | QUENCHING DYE FOR LABELING BIOMOLECULES AND METHOD FOR PREPARING THE SAME | DKC CORPORATION (KR) | 2016-09-15 | — | — | US | disclosed |
| US-9440166-B2 | Method and device to extract an analyte from a sample with gas assistance | DIONEX CORPORATION (US) | 2016-09-13 | — | — | US | disclosed |
| US-20160257642-A1 | ANTIMICROBIAL COMPOUNDS | AKTHELIA PHARMACEUTICALS (IS) | 2016-09-08 | — | — | US | disclosed |
| EP-3062784-A1 | ANTIMICROBIAL COMPOUNDS | Akthelia Pharmaceuticals (IS) | 2016-09-07 | — | — | EP | disclosed |
| CN-105486763-A | Quality detection method for Kunling Wan and application thereof | TASLY PHARMACEUTICAL GROUP CO | 2016-04-13 | — | — | CN | disclosed |
| WO-2016042084-A1 | BENZYL SUBSTITUTED INDAZOLES AS BUB1 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-03-24 | — | — | WO | disclosed |
| CN-104844555-A | Alkaloid compound, drug composition, preparation method and uses thereof | INST PHARM & TOXICOLOGY AMMS | 2015-08-19 | — | — | CN | disclosed |
| US-20150197492-A1 | NOVEL INDENO[1,2-c]QUINOLIN-11-ONE DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2015-07-16 | — | — | US | disclosed |
| CN-103058974-B | Natural compound and preparation method and application thereof | INST PHARM & TOXICOLOGY AMMS | 2015-06-10 | — | — | CN | disclosed |
| WO-2015063694-A1 | ANTIMICROBIAL COMPOUNDS | AKTHELIA PHARMACEUTICALS (IS) | 2015-05-07 | — | — | WO | disclosed |
| EP-2576559-B1 | INHIBITORS OF JNK | HOFFMANN LA ROCHE (CH) | 2015-03-04 | — | — | EP | disclosed |
| US-8927672-B2 | Benzindocyanine compound for labeling substance, intermediate thereof, and method for preparing the same | DKC CORPORATION (KR) | 2015-01-06 | — | — | US | disclosed |
| CN-103058839-B | Process for synthesizing and purifying teprenone | SICHUAN YUANJI PHARMACEUTICAL CO LTD | 2014-12-17 | — | — | CN | disclosed |
| EP-2763982-A1 | SUBSTITUTED BENZYLINDAZOLES FOR USE AS BUB1 KINASE INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES. | Bayer Pharma Aktiengesellschaft (DE) | 2014-08-13 | — | — | EP | disclosed |
| US-8729276-B2 | Cyanine compound for labeling biomolecule and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-05-20 | — | — | US | disclosed |
| CN-102531906-B | Application of natural compound P21 in inhibition of reproductive growth of tumor cell | UNIV BEIJING | 2014-03-19 | — | — | CN | disclosed |
| CN-101890077-B | Preparation method and quality detection method of rhizoma corydalis pain relieving soft capsules | JIANGSU KANION PHARMACEUTICAL | 2013-11-06 | — | — | CN | disclosed |
| US-8546398-B2 | Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20130210814-A1 | Cycloalkyl Substituted Pyrimidinediamine Compounds And Their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| CN-102807955-B | Method for preparing anti-tumor compound Rasfonin and special strain of method | INST PHARM & TOXICOLOGY AMMS | 2013-07-31 | — | — | CN | disclosed |
| US-20130102752-A1 | BENZINDOCYANINE COMPOUND FOR LABELING SUBSTANCE, INTERMEDIATE THEREOF, AND METHOD FOR PREPARING THE SAME | DKC CORPORATION (KR) | 2013-04-25 | — | — | US | disclosed |
| CN-103058974-A | Natural compound and preparation method and application thereof | INST PHARM & TOXICOLOGY AMMS | 2013-04-24 | — | — | CN | disclosed |
| CN-103058839-A | Process for synthesizing and purifying teprenone | SICHUAN YUANJI PHARMACEUTICAL CO LTD | 2013-04-24 | — | — | CN | disclosed |
| WO-2013050438-A1 | SUBSTITUTED BENZYLINDAZOLES FOR USE AS BUB1 KINASE INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES. | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-04-11 | — | — | WO | disclosed |
| EP-2576559-A1 | INHIBITORS OF JNK | F.HOFFMANN-LA ROCHE AG (CH) | 2013-04-10 | — | — | EP | disclosed |
| US-8410093-B2 | Cycloalkyl substituted pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2013-04-02 | — | — | US | disclosed |
| CN-102807955-A | Method for preparing anti-tumor compound Rasfonin and special strain of method | INST PHARM & TOXICOLOGY AMMS | 2012-12-05 | — | — | CN | disclosed |
| CN-102795971-A | Method for extracting high-purity antitumor substance oxyresveratrol from chinaroot greenbrier | YANTAI BOHAI PHARMACEUTICALS GROUP CO LTD | 2012-11-28 | — | — | CN | disclosed |
| US-8288527-B2 | Oligo-aminosaccharide compound | THE UNIVERSITY OF TOKYO (JP) | 2012-10-16 | — | — | US | disclosed |
| CN-102675070-A | Preparation method of agroskerin | NANJING ZELANG MEDICAL TECH CO | 2012-09-19 | — | — | CN | disclosed |
| CN-102675070-A | Preparation method of agroskerin | NANJING ZELANG MEDICAL TECH CO | 2012-09-19 | — | — | CN | disclosed |
| CN-102531906-A | Application of natural compound P21 in inhibition of reproductive growth of tumor cell | UNIV BEIJING | 2012-07-04 | — | — | CN | disclosed |
| US-20120095187-A1 | NOVEL CYANINE COMPOUND FOR LABELING BIOMOLECULE AND PREPARATION METHOD THEREOF | DKC CORPORATION (KR) | 2012-04-19 | — | — | US | disclosed |
| US-8101627-B2 | Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| CN-101700287-B | Traditional Chinese medicine composition for treating gastropathy and preparation method and quality control method thereof | SHAANXI DONGTAI PHARMACEUTICAL CO LTD | 2012-01-11 | — | — | CN | disclosed |
| US-20110301170-A1 | Inhibitors of JNK | GONG LEYI (US) | 2011-12-08 | — | — | US | disclosed |
| WO-2011151357-A1 | INHIBITORS OF JNK | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| US-8044054-B2 | Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-20110190344-A1 | BENZIMIDAZOLE MODULATORS OF VR1 | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-08-04 | — | — | US | disclosed |
| CN-101280326-B | Preparation and application of compound for inhabiting aspergillus fumigatus activity | CHINESE ACAD INST MICROBIOLOGY | 2011-07-06 | — | — | CN | disclosed |
| US-20110152518-A1 | Cycloalkyl Substituted Pyrimidinediamine Compounds And Their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-7951829-B2 | Benzimidazole modulators of VR1 | JANSSEN PHARMACEUTICA NV (BE) | 2011-05-31 | — | — | US | disclosed |
| US-20110098477-A1 | Method Of Producing Compound Having Anti-Hcv Activity | CHUGAI SEIYAKU KABUSHIKI KAISHA | 2011-04-28 | — | — | US | disclosed |
| US-7868013-B2 | Cycloalkyl substituted pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| US-20110003980-A1 | Oligo-Aminosaccharide compound | THE UNIVERSITY OF TOKYO (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-1824489-B1 | STEREOISOMERICALLY ENRICHED 3-AMINOCARBONYL BICYCLOHEPTENE PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | RIGEL PHARMACEUTICALS INC (US) | 2011-01-05 | — | — | EP | disclosed |
| US-7863286-B2 | Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2011-01-04 | — | — | US | disclosed |
| US-7858633-B2 | Cycloalkyl substituted pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| EP-2252372-A1 | 2-AMINOQUINOLINES | F. Hoffmann-La Roche AG (CH) | 2010-11-24 | — | — | EP | disclosed |
| CN-101890077-A | Preparation method and quality detection method of rhizoma corydalis pain relieving soft capsules | JIANGSU KANION PHARMACEUTICAL | 2010-11-24 | — | — | CN | disclosed |
| US-7812037-B2 | Dual antiplatelet/anticoagulant pyridoxine analogs | MEDICURE INTERNATIONAL, INC. (BB) | 2010-10-12 | — | — | US | disclosed |
| US-7754714-B2 | (1S, 2R)-N4-(2-Aminocarbonylcyclopent-1-yl)-5-fluoro-N2-[4-(4-methylpiperazin-1-yl)-3-methylphenyl]-2,4-pyrimidinediamine, having antiproliferative activity, used to inhibit cellular proliferation and to treat proliferate diseases such as cancers | RIGEL PHARMACEUTICALS, INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20100150865-A1 | NOVEL FORMULATIONS TO INHIBIT CYCLOOXYGENASE AND PRO-INFLAMMATORY CYTOKINE MEDIATED DISEASES | BIO-VED PHARMACEUTICALS, INC | 2010-06-17 | — | — | US | disclosed |
| CN-101700287-A | Traditional Chinese medicine composition for treating gastropathy and preparation method and quality control method thereof | EASTANTAI PHARMACEUTICAL CO LT | 2010-05-05 | — | — | CN | disclosed |
| EP-1549651-B1 | PYRIMIDOPYRIMIDONES AS KINASE INHIBITORS | WARNER LAMBERT CO (US) | 2009-12-23 | — | — | EP | disclosed |
| US-20090312438-A1 | Compositions and Methods for Attenuating the Formation of A2E in the Retinal Pigment Epithelium | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-12-17 | — | — | US | disclosed |
| US-7618968-B2 | Aryl triazines as LPAAT-β inhibitors and uses thereof | CELL THERAPEUTICS, INC. (US) | 2009-11-17 | — | — | US | disclosed |
| US-20090270399-A1 | NOVEL PYRIDAZINE DERIVATIVES AND MEDICINES CONTAINING THE SAME AS EFFECTIVE INGREDIENTS | KOWA CO., LTD. (JP) | 2009-10-29 | — | — | US | disclosed |
| WO-2009109502-A1 | 2-AMINOQUINOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-11 | — | — | WO | disclosed |
| US-20090226546-A1 | COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS | D-HERB LTD. (IL) | 2009-09-10 | — | — | US | disclosed |
| EP-1817288-A4 | DUAL ANTIPLATELET/ANTICOAGULANT PYRIDOXINE ANALOGS | MEDICURE INT INC (BB) | 2009-08-26 | — | — | EP | disclosed |
| EP-1706123-A4 | COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS | HERB LTD D (IL) | 2009-07-15 | — | — | EP | disclosed |
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20090137589-A1 | Stereoisomerically Enriched 3-Aminocarbonyl Bicycloheptene Pyrimidinediamine Compounds And Their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | US | disclosed |
| EP-1043317-B1 | PYRIDAZINE DERIVATIVES AND MEDICAMENTS CONTAINING THEM AS ACTIVE INGREDIENT | KOWA CO (JP) | 2009-04-15 | — | — | EP | disclosed |
| US-20090069332-A1 | NOVEL PYRIDAZINE DERIVATIVES AND MEDICINES CONTAINING THE SAME AS EFFECTIVE INGREDIENTS | KOWA CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| EP-0966443-B1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SELECTIVE INHIBITORS OF MIP-1-ALPHA BINDING TO ITS CCR1 RECEPTOR | PFIZER (US) | 2009-01-28 | — | — | EP | disclosed |
| EP-2017266-A1 | Pyridazine derivatives and medicines containing the same as effective ingredients | Kowa Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
| US-20080311099-A1 | Pyridoxal-5-Phosphate and Related Compounds in Combination With Therapeutic Cardiovascular Compounds for Treating Angina | MEDICURE INTERNATIONAL INC. | 2008-12-18 | — | — | US | disclosed |
| US-7442689-B2 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2008-10-28 | — | — | US | disclosed |
| US-7439265-B2 | Irciniastatins a and b | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2008-10-21 | — | — | US | disclosed |
| CN-101280326-A | Preparation and application of compound for inhabiting aspergillus fumigatus activity | CHINESE ACAD INST MICROBIOLOGY (CN) | 2008-10-08 | — | — | CN | disclosed |
| US-20080119474-A1 | NOVEL PYRIDAZINE DERIVATIVES AND MEDICINES CONTAINING THE SAME AS EFFECTIVE INGREDIENTS | KOWA CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1908846-A1 | METHOD OF PRODUCING COMPOUND HAVING ANTI-HCV ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-04-09 | — | — | EP | disclosed |
| EP-1531157-B1 | Cardioprotective phosphonates | MEDICURE INT INC (BB) | 2008-03-19 | — | — | EP | disclosed |
| US-20080064700-A1 | Aryl triazines as LPAAT-beta inhibitors and uses thereof | CELL THERAPEUTICS, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| US-20080051412-A1 | Stereoisomerically Enriched 3-Aminocarbonyl Bicycloheptene Pyrimidinediamine Compounds and their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2008-02-28 | — | — | US | disclosed |
| EP-1556384-B1 | PYRIMIDO COMPOUNDS HAVING ANTIPROLIFERATIVE ACTIVITY | HOFFMANN LA ROCHE (CH) | 2008-02-20 | — | — | EP | disclosed |
| US-20080009494-A1 | Cycloalkyl Substituted Pyrimidinediamine Compounds And Their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2008-01-10 | — | — | US | disclosed |
| US-20070299060-A1 | Cycloalkyl Substituted Pyrimidinediamine Compounds And Their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2007-12-27 | — | — | US | disclosed |
| US-20070259936-A1 | Benzimidazole Modulators of VR1 | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-08 | — | — | US | disclosed |
| US-7291616-B2 | Aryl triazines as LPAAT-β inhibitors and uses thereof | CELL THERAPEUTICS, INC. (US) | 2007-11-06 | — | — | US | disclosed |
| US-20070208025-A1 | NOVEL PYRIDAZINE DERIVATIVES AND MEDICINES CONTAINING THE SAME AS EFFECTIVE INGREDIENTS | KOWA CO., LTD. (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1692125-A4 | IRCINIASTATINS A AND B | UNIV ARIZONA (US) | 2007-08-29 | — | — | EP | disclosed |
| EP-1824489-A2 | STEREOISOMERICALLY ENRICHED 3-AMINOCARBONYL BICYCLOHEPTENE PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | Rigel Pharmaceuticals, Inc. (US) | 2007-08-29 | — | — | EP | disclosed |
| EP-1817288-A1 | DUAL ANTIPLATELET/ANTICOAGULANT PYRIDOXINE ANALOGS | Medicure International Inc. (BB) | 2007-08-15 | — | — | EP | disclosed |
| US-20070179140-A1 | Stereoisomerically Enriched 3-Aminocarbonyl Bicycloheptene Pyrimidinediamine Compounds And Their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2007-08-02 | — | — | US | disclosed |
| US-20070167411-A1 | Compositions for treating angina | MEDICURE INTERNATIONAL INC. (BB) | 2007-07-19 | — | — | US | disclosed |
| US-20070154572-A1 | Compositions derived from portulaca oleracea l. and methods of using same for modulating blood glucose levels | D-HERB LTD. (IL) | 2007-07-05 | — | — | US | disclosed |
| CN-1323080-C | Pyrimido compounds having antiproliferative activity | HOFFMANN LA ROCHE (CH) | 2007-06-27 | — | — | CN | disclosed |
| EP-1796685-A1 | PYRIDOXAL-5´-PHOSPHATE AND RELATED COMPOUNDS IN COMBINATION WITH THERAPEUTIC CADIOVASCULAR COMPOUNDS FOR TREATING ANGINA. | Medicure International Inc. (CA) | 2007-06-20 | — | — | EP | disclosed |
| US-20070135516-A1 | Irciniastatins a and b | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-06-14 | — | — | US | disclosed |
| US-20070077546-A1 | Concentration techniques in chromatographic separation | AGILENT TECHNOLOGIES, INC. | 2007-04-05 | — | — | US | disclosed |
| US-7196090-B2 | Kinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2007-03-27 | — | — | US | disclosed |
| EP-1763514-A2 | CYCLOALKYL SUBSTITUTED PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | Rigel Pharmaceuticals, Inc. (US) | 2007-03-21 | — | — | EP | disclosed |
| US-7176210-B2 | Cannabinoid receptor ligands and uses thereof | PFIZER INC. (US) | 2007-02-13 | — | — | US | disclosed |
| US-20070032456-A1 | Modulation of cell death | MEDICURE INC. (CA) | 2007-02-08 | — | — | US | disclosed |
| US-7173041-B2 | Polyglutamic acid-camptothecin conjugates and methods of preparation | CELL THERAPEUTICS INC. (US) | 2007-02-06 | — | — | US | disclosed |
| WO-2007004049-A1 | OXAZOLIDINONES CONTAINING AZETIDINE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-11 | — | — | WO | disclosed |
| US-7153864-B2 | Polyglutamic acid-camptothecin conjugates and methods of preparation | CELL THERAPEUTICS INC. (US) | 2006-12-26 | — | — | US | disclosed |
| WO-2006107646-A1 | ARYLPYRENE COMPOUNDS | UNIVERSAL DISPLAY CORPORATION (US) | 2006-10-12 | — | — | WO | disclosed |
| US-20060222886-A1 | Arylpyrene compounds | UNIVERSAL DISPLAY CORPORATION | 2006-10-05 | — | — | US | disclosed |
| EP-1706123-A2 | COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS | D-Herb Ltd. (IL) | 2006-10-04 | — | — | EP | disclosed |
| US-7105673-B2 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2006-09-12 | — | — | US | disclosed |
| EP-1051405-B1 | NOVEL DIHYDROXYHEXANOIC ACID DERIVATIVES | PFIZER PROD INC (US) | 2006-08-23 | — | — | EP | disclosed |
| EP-1692125-A2 | IRCINIASTATINS A AND B | Arizona Board of Regents (US) | 2006-08-23 | — | — | EP | disclosed |
| US-7084270-B2 | Pyrimido compounds having antiproliferative activity | HOFFMAN-LA ROCHE INC. (US) | 2006-08-01 | — | — | US | disclosed |
| US-20060167249-A1 | Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2006-07-27 | — | — | US | disclosed |
| EP-1082338-B1 | 17 BETA-NITRO-11 BETA-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES | RES TRIANGLE INST (US) | 2006-07-26 | — | — | EP | disclosed |
| US-20060160804-A1 | Novel pyridazine derivatives and medicines containing the same as effective ingredients | KOWA CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
| EP-1082337-B1 | 17 BETA-AMINO AND HYDROXYLAMINO-11 BETA-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES | RES TRIANGLE INST (US) | 2006-07-19 | — | — | EP | disclosed |
| WO-2006058411-A1 | PYRIDOXAL-5´-PHOSPHATE AND RELATED COMPOUNDS IN COMBINATION WITH THERAPEUTIC CADIOVASCULAR COMPOUNDS FOR TREATING ANGINA. | MEDICURE INTERNATIONAL INC. (CA) | 2006-06-08 | — | — | WO | disclosed |
| WO-2006055561-A2 | STEREOISOMERICALLY ENRICHED 3-AMINOCARBONYL BICYCLOHEPTENE PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | RIGEL PHARMACEUTICALS, INC. (US) | 2006-05-26 | — | — | WO | disclosed |
| WO-2006050598-A1 | DUAL ANTIPLATELET/ANTICOAGULANT PYRIDOXINE ANALOGS | MEDICURE INTERNATIONAL INC. (CA) | 2006-05-18 | — | — | WO | disclosed |
| US-20060094761-A1 | Dual antiplatelet/anticoagulant pyridoxine analogs | MEDICURE INTERNATIONAL INC. (CA) | 2006-05-04 | — | — | US | disclosed |
| WO-2006038112-A1 | USE OF KINASE INHIBITORS TO PROMOTE NEOCHONDROGENESIS | WARNER-LAMBERT COMPANY LLC (US) | 2006-04-13 | — | — | WO | disclosed |
| US-7018991-B2 | 17β-amino and hydroxylamino-11 β-arylsteroids and their derivatives having agonist or antagonist hormonal properties | RESEARCH TRIANGLE INSTITUTE (US) | 2006-03-28 | — | — | US | disclosed |
| US-20060035891-A1 | Cycloalkyl substituted pyrimidinediamine compounds and their uses | MIDCAP FINANCIAL TRUST | 2006-02-16 | — | — | US | disclosed |
| EP-1610783-A2 | MODULATION OF CELL DEATH | Medicure Inc. (CA) | 2006-01-04 | — | — | EP | disclosed |
| EP-1608379-A1 | COMPOSITIONS FOR TREATING ANGINA | Medicure Inc. (CA) | 2005-12-28 | — | — | EP | disclosed |
| WO-2005118544-A2 | CYCLOALKYL SUBSTITUTED PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | RIGEL PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| US-20050267113-A1 | Novel pyridazine derivatives and medicines containing the same as effective ingredients | KOWA CO., LTD. (JP) | 2005-12-01 | — | — | US | disclosed |
| EP-1594872-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | Pfizer Products Inc. (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2005105257-A1 | CHROMATOGRAPHIC STATIONARY PHASE FOR SEPARATION OF CYCLODEXTRINE AND DERIVATIVES THEREOF | CHIROQUEST KIRÁLIS TECHNOLÓGIÁKAT FEJLESZTÖ KFT. (HU) | 2005-11-10 | — | — | WO | disclosed |
| WO-2005103052-A1 | PYRAZOLO [1,5-A] PYRIMIDIN-7-ONE COMPOUNDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-11-03 | — | — | WO | disclosed |
| CN-1675214-A | Pyrimido compounds having antiproliferative activity | HOFFMANN LA ROCHE (CH) | 2005-09-28 | — | — | CN | disclosed |
| EP-1556384-A2 | PYRIMIDO COMPOUNDS HAVING ANTIPROLIFERATIVE ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2005-07-27 | — | — | EP | disclosed |
| EP-0929526-B1 | QINOLINE DERIVATIVES INHIBITING THE EFFECT OF GROWTH FACTORS SUCH AS VEGF | ASTRAZENECA AB (SE) | 2005-07-27 | — | — | EP | disclosed |
| WO-2005060349-A2 | COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS | D-HERB LTD. (IL) | 2005-07-07 | — | — | WO | disclosed |
| EP-1549651-A1 | KINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2005054809-A2 | IRCINIASTATINS A AND B | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2005-06-16 | — | — | WO | disclosed |
| EP-1531157-A1 | Cardioprotective phosphonates | Medicure International Inc. (BB) | 2005-05-18 | — | — | EP | disclosed |
| EP-1194429-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2005-03-30 | — | — | EP | disclosed |
| US-20050065155-A1 | Novel pyridazine derivatives and medicines containing the same as effective ingredients | KOWA CO., LTD. (JP) | 2005-03-24 | — | — | US | disclosed |
| US-6867215-B2 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2005-03-15 | — | — | US | disclosed |
| US-6861439-B2 | Treatment of cerebrovascular disease | MEDICURE INTERNATIONAL, INC. (BB) | 2005-03-01 | — | — | US | disclosed |
| US-6855730-B2 | 3-methylidenyl-2-indolinone modulators of protein kinase | SUGEN, INC. (US) | 2005-02-15 | — | — | US | disclosed |
| US-20050026836-A1 | Composition for the treatment of damaged tissue | DACK KEVIN NEIL (GB) | 2005-02-03 | — | — | US | disclosed |
| EP-1082338-A4 | 17 BETA-NITRO-11 BETA-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES | RES TRIANGLE INST (US) | 2004-12-29 | — | — | EP | disclosed |
| EP-1082337-A4 | 17 BETA-AMINO AND HYDROXYLAMINO-11 BETA-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES | RES TRIANGLE INST (US) | 2004-12-29 | — | — | EP | disclosed |
| US-6809097-B1 | ANTIANGIOGENIC AND/OR VASCULAR PERMEABILITY | ZENECA LIMITED (GB) | 2004-10-26 | — | — | US | disclosed |
| WO-2004084910-A1 | COMPOSITIONS FOR TREATING ANGINA | MEDICURE INC. (CA) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004084895-A2 | MODULATION OF CELL DEATH | MEDICURE, INC. (CA) | 2004-10-07 | — | — | WO | disclosed |
| US-20040171588-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (CA) | 2004-09-02 | — | — | US | disclosed |
| US-6780997-B2 | SUCH AS DIBENZYL(A,3-O-ISOPROPYLIDIENE-3-HYDROXY-4-HYDROXYMETHYL-2-METHYL-5-PYRIDYL) HYDROXYMETHYLPHOSPHONATE WHICH FUNCTIONS LIKE PYRIDOXAL-5'-PHOSPHATE IN VIVO; DRUG SCREENING; ANTIDIABETIC AGENTS | MEDICURE INTERNATIONAL INC. (BB) | 2004-08-24 | — | — | US | disclosed |
| WO-2004069838-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2004-08-19 | — | — | WO | disclosed |
| US-20040157838-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC | 2004-08-12 | — | — | US | disclosed |
| US-20040147516-A1 | Novel pyridazine derivatives and medicines containing the same as effective ingredients | KOWA CO., LTD. (JP) | 2004-07-29 | — | — | US | disclosed |
| US-20040121988-A1 | Treatment of cerebrovascular disease | MEDICURE INTERNATIONAL INC. (BB) | 2004-06-24 | — | — | US | disclosed |
| WO-2004039375-A1 | METHODS OF USING CCR1 ANTAGONISTS AS IMMUNOMODULATORY AGENTS | PFIZER PRODUCTS INC. (US) | 2004-05-13 | — | — | WO | disclosed |
| US-20040087571-A1 | Methods of using CCR1 antagonists as immunomodulatory agents | PFIZER INC | 2004-05-06 | — | — | US | disclosed |
| EP-1040097-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2004-04-14 | — | — | EP | disclosed |
| EP-1118616-B1 | Process for the production of 5'-nor-anhydrovinblastine ditartrate from plants of genus catharanthus | ERIOCHEM SA (AR) | 2004-03-24 | — | — | EP | disclosed |
| US-6710164-B1 | COMPRISING AT LEAST ONE C1-C8 ALKYLAMINE SIDE CHAIN | NIELSEN PETER E (DK) | 2004-03-23 | — | — | US | disclosed |
| CN-1142148-C | Novel pyridazine derivative and drug containing the same as active ingredient | ������������ʽ���� | 2004-03-17 | — | — | CN | disclosed |
| WO-2004018472-A2 | PYRIMIDO COMPOUNDS HAVING ANTIPROLIFERATIVE ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2004-03-04 | — | — | WO | disclosed |
| US-20040038995-A1 | Pyrimido compounds having antiproliferative activity | CHEN YI (US) | 2004-02-26 | — | — | US | disclosed |
| EP-0883405-B1 | AMIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2004-02-25 | — | — | EP | disclosed |
| US-20040033273-A1 | Withasol and methods of use | AYURCORE, INC. | 2004-02-19 | — | — | US | disclosed |
| CN-1138773-C | 4-alkenyl (and alkynyl) oxindoles as inhibitors of cell cycle protein dependent kinases, in particular CDK2 | - | 2004-02-18 | — | — | CN | disclosed |
| US-20040024010-A1 | 3-methylidenyl-2-indolinone modulators of protein kinase | SUGEN, INC. | 2004-02-05 | — | — | US | disclosed |
| US-20040023936-A1 | 17 Beta-amino and hydroxylamino-11 beta-arylsteroids and their derivatives having agonist or antagonist hormonal properties | RESEARCHTRIANGLE INSTITUTE | 2004-02-05 | — | — | US | disclosed |
| WO-2004011465-A1 | KINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-05 | — | — | WO | disclosed |
| US-6686442-B2 | PEPTIDE NUCLEIC ACID FOR USE IN VETERINARY MEDICINE | Neilsen, Peter E. (DK) | 2004-02-03 | — | — | US | disclosed |
| US-20040019210-A1 | Kinase inhibitors | CHIVIKAS CONNOLLY CLEO J (US) | 2004-01-29 | — | — | US | disclosed |
| US-6677333-B1 | ANTIISCHEMIC AGENTS; BRAIN, CARDIOVASCULAR, MUSCULAR, AND GASTROINTESTINAL DISORDERS; ANALGESICS, ANTIDIABETIC AGENTS; RETROVIRUS SENSITIZERS; ALZHEIMER*S DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-01-13 | — | — | US | disclosed |
| US-6673801-B1 | TREATING MULTIPLE SCLEROSIS OR RHEUMATOID ARTHRITIS | PFIZER INC. | 2004-01-06 | — | — | US | disclosed |
| US-6667315-B2 | Pyridoxine phosphonate analogues such as, for example, ((2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)alkylphosphonates, and (2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)azaalkylphosphonates) | MEDICURE INTERNATIONAL INC. (BA) | 2003-12-23 | — | — | US | disclosed |
| US-20030216289-A1 | Polyglutamic acid-camptothecin conjugates and methods of preparation | CELL THERAPEUTICS, INC. | 2003-11-20 | — | — | US | disclosed |
| US-20030211973-A1 | Polyglutamic acid-camptothecin conjugates and methods of preparation | CELL THERAPEUTICS, INC. | 2003-11-13 | — | — | US | disclosed |
| US-6642222-B2 | Useful in hyperpolarizing cell membranes, opening potassium channels, relaxing smooth muscle cells, and inhibiting bladder contractions | ABBOTT LABORATORIES | 2003-11-04 | — | — | US | disclosed |
| US-20030199440-A1 | Composition for the treatment of damaged tissue | PFIZER INC. | 2003-10-23 | — | — | US | disclosed |
| US-6632418-B2 | Therapy for asthma, sexual disorders, hypotensive agents, analgesics | ABBOTT LABORATORIES | 2003-10-14 | — | — | US | disclosed |
| US-20030181422-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2003-09-25 | — | — | US | disclosed |
| US-6620801-B2 | 17 beta-amino and hydroxylamino steroids which are believed to bind to the progestin receptor and exhibit potent antiprogestational activity | RESEARCH TRIANGLE INSTITUTE | 2003-09-16 | — | — | US | disclosed |
| US-20030153570-A1 | Aryl triazines as LPAAT-SS inhibitors and uses thereof | CELL THERAPEUTICS, INC. (US) | 2003-08-14 | — | — | US | disclosed |
| US-6605612-B2 | Derivatives of 5-pyridylalkylphosphonates and 5-pyridylalkylmalonates useful drugs for treatment of cardiovascular related diseases and diabetes mellitus related diseases | MEDICURE INTERNATIONAL INC. (BB) | 2003-08-12 | — | — | US | disclosed |
| US-6593332-B2 | Phosphodiesterase inhibitors; sexual disorders | PFIZER INC. | 2003-07-15 | — | — | US | disclosed |
| US-6593335-B1 | Disease than can be ameliorated with a potassium channel opener in a host mammal, comprising administering to the mammal in need thereof a therapeutically effective amount of the compound of claim 1; said disease is epilepsy, Raynaud's | ABBOTT LABORATORIES | 2003-07-15 | — | — | US | disclosed |
| CN-1429121-A | Polyglutamic acid-camptothecin conjugates and methods of preparation | CELL TERAPEUTICS INC (US) | 2003-07-09 | — | — | CN | disclosed |
| CN-1113066-C | Novel peptide derivatives | TEIKOKU HORMONE MFG CO LTD (JP) | 2003-07-02 | — | — | CN | disclosed |
| US-6586439-B2 | Therapy for sexual disorders | PFIZER INC. | 2003-07-01 | — | — | US | disclosed |
| US-6586414-B2 | Administering pyridoxal-5'-phosphate, pyridoxal, pyridoxine, pyridoxamine, 3-acylated analogues thereof; treatment of strokes | MEDICURE INTERNATIONAL INC. (BB) | 2003-07-01 | — | — | US | disclosed |
| US-20030120074-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2003-06-26 | — | — | US | disclosed |
| US-20030114424-A1 | Treatment of cerebrovascular disease | MEDICURE INTERNATIONAL INC. (BB) | 2003-06-19 | — | — | US | disclosed |
| US-20030114678-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2003-06-19 | — | — | US | disclosed |
| US-20030114677-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2003-06-19 | — | — | US | disclosed |
| WO-2003045381-A1 | AMINOALKYLIMIDAZOLE DERIVATIVES AND THEIR USE IN MEDICINE | MOLECULAR SKINCARE LIMITED (GB) | 2003-06-05 | — | — | WO | disclosed |
| EP-1180034-A4 | NOVEL EPIDERMAL GROWTH FACTOR RECEPTOR-BINDING COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY | HADASIT MED RES SERVICE (IL) | 2003-05-14 | — | — | EP | disclosed |
| US-6562319-B2 | 4-(phenylamino)quinazolines | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-05-13 | — | — | US | disclosed |
| WO-2003037346-A1 | 6-PHENYL-N-PHENYL-(1,3,5) -TRIAZINE-2,4-DIAMINE DERIVATIVES AND RELATED COMPOUNDS WITH LYSOPHPHOSPHATIDIC ACID ACYLTRANSFERASE BETA (LPAAT-BETA) INHIBITORY ACTIVITY FOR USE IN THE TREATMENT OF CANCER | CELL THERAPEUTICS, INC. (US) | 2003-05-08 | — | — | WO | disclosed |
| EP-0611756-B1 | Alcohol or aldehyde derivatives as cathepsin L inhibitor and bone resorption inhibitor | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | disclosed |
| US-20030065182-A1 | Novel radioligands and their use for identifying potassium channel modulators | ABBOTT LABORATORIES | 2003-04-03 | — | — | US | disclosed |
| US-20030059462-A1 | Carotenoid-loaded liposomes | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY (IL) | 2003-03-27 | — | — | US | disclosed |
| US-20030055035-A1 | Pyrano piperidino and thiopyrano compounds and methods of use | ABBOTT LABORATORIES | 2003-03-20 | — | — | US | disclosed |
| WO-2003011869-A1 | RADIOLIGANDS AND THEIR USE FOR IDENTIFYING POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2003-02-13 | — | — | WO | disclosed |
| EP-1278746-A2 | DIHYDROPYRIDINE COMPOUNDS AND METHODS OF USE | Abbott Laboratories (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-1278526-A2 | TREATMENT OF CEREBROVASCULAR DISEASE | Medicure International Inc. (BB) | 2003-01-29 | — | — | EP | disclosed |
| EP-1278747-A1 | PYRANO, PIPERIDINO, AND THIOPYRANO COMPOUNDS AND METHODS OF USE | Abbott Laboratories (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6511993-B1 | Substituted alpha-aminosulphonyl-acetohydroxamic acids which are inhibitors of zinc-dependent metalloprotease enzymes | PFIZER INC. | 2003-01-28 | — | — | US | disclosed |
| US-20030018033-A1 | Novel dihydroxyhexanoic acid derivatives | KATH JOHN CHARLES (US) | 2003-01-23 | — | — | US | disclosed |
| US-20030013727-A1 | Pharmaceutically active compounds | MAW GRAHAM NIGEL (GB) | 2003-01-16 | — | — | US | disclosed |
| EP-1268498-A1 | CARDIOPROTECTIVE PHOSPHONATES AND MALONATES | Medicure International Inc. (BB) | 2003-01-02 | — | — | EP | disclosed |
| EP-1267939-A2 | POLYGLUTAMIC ACID-CAMPTOTHECIN CONJUGATES AND METHODS OF PREPARATION | CELL THERAPEUTICS, INC. (US) | 2003-01-02 | — | — | EP | disclosed |
| US-20030004173-A1 | Pharmaceutically active compounds | MAW GRAHAM NIGEL (GB) | 2003-01-02 | — | — | US | disclosed |
| US-20020188101-A1 | Conjugated peptide nucleic acids having enhanced cellular uptake | ISIS PHARMACEUTICALS, INC. | 2002-12-12 | — | — | US | disclosed |
| US-20020183243-A1 | Polyglutamic acid-camptothecin conjugates and methods of preparation | CELL THERAPEUTICS, INC. | 2002-12-05 | — | — | US | disclosed |
| US-20020146718-A1 | Peptide nucleic acids having 2,6-diaminopurine nucleobases | BUCHARDT OLE (DK) | 2002-10-10 | — | — | US | disclosed |
| WO-2002079748-A2 | WITHASOL AND METHODS OF USE | BIO-VED PHARMACEUTICALS, INC. (US) | 2002-10-10 | — | — | WO | disclosed |
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| US-20020128553-A1 | Radiolabeled irreversible inhibitors of epidermal growth factor receptor tyrosine kinase and their use in radioimaging and radiotherapy | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. | 2002-09-12 | — | — | US | disclosed |
| US-6440982-B1 | INHIBITORS OF CYCLIC GUANOSINE MONOPHOSPHATE DIESTERASES | PFIZER INC. | 2002-08-27 | — | — | US | disclosed |
| US-6414003-B1 | ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-6414020-B2 | ANTIPROTEOLYTIC AMIDINO OR DERIVATIVE USEFUL FOR TREATING PENCREATITIS, THROMBOSIS, ISCHEMIA, STROKE, RESTENOSIS, EMPHYSEMA OR INFLAMMATION | 3- DIMENSIONAL PHARMACEUTICALS, INC. | 2002-07-02 | — | — | US | disclosed |
| US-6414112-B1 | BIND COMPLEMENTARY NUCLEIC ACIDS MORE STRONGLY AND HAVE INCREASED SEQUENCE SPECIFICITY AND BINDING AFFINITY | BUCHARDT OLE (DE) | 2002-07-02 | — | — | US | disclosed |
| US-20020077290-A1 | Polyglutamic acid-camptothecin conjugates and methods of preparation | CELL THERAPEUTICS, INC. | 2002-06-20 | — | — | US | disclosed |
| US-6403587-B1 | AUTOIMMUNE DISEASES, ACUTE AND CHRONIC INFLAMMATORY CONDITIONS, ALLERGIC CONDITIONS, INFECTION ASSOCIATED WITH INFLAMMATION, VIRAL, TRANSPLANTATION TISSUE REJECTION, ATHEROSCLEROSIS, RESTENOSIS, HIV INFECTIVITY, AND | PFIZER INC. | 2002-06-11 | — | — | US | disclosed |
| EP-0888337-B1 | PIPERIDONE TACHYKININ ANTAGONISTS | PFIZER RES & DEV (IE) | 2002-06-05 | — | — | EP | disclosed |
| US-20020065257-A1 | 17beta-amino and hydroxylamino-11beta-arylsteroids and their derivatives having agonist or antagonist hormonal properties | RESEARCH TRIANGLE INSTITUTE (US) | 2002-05-30 | — | — | US | disclosed |
| US-6395762-B1 | METABOLISM DISEASES; HYPOGLYCEMIC AGENTS; ANTICHOLESTEROL AGENTS; ANTIDIABETIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION | 2002-05-28 | — | — | US | disclosed |
| EP-1194429-A1 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-10 | — | — | EP | disclosed |
| US-20020025973-A1 | Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-02-28 | — | — | US | disclosed |
| EP-1180034-A1 | NOVEL EPIDERMAL GROWTH FACTOR RECEPTOR-BINDING COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY | HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED (IL) | 2002-02-20 | — | — | EP | disclosed |
| US-6348468-B1 | THESE COMPOUNDS HAVE EXCELLENT INHIBITORY ACTIVITY AGAINST INTERLEUKIN-1.BETA. PRODUCTION, IMMUNE SYSTEM DISEASES, INFLAMMATORY DISEASES, ISCHEMIC DISEASES AND THE LIKE. | KOWA CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |
| US-20020016285-A1 | Polyglutamic acid-camptothecin conjugates and methods of preparation | CELL THERAPEUTICS, INC. | 2002-02-07 | — | — | US | disclosed |
| US-20020010158-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (CA) | 2002-01-24 | — | — | US | disclosed |
| EP-0973784-B1 | PREPARATION OF TERTIARY PHOSPHINES VIA NICKEL-CATALYZED CROSS COUPLING | PCBU SERVICES INC (US) | 2002-01-16 | — | — | EP | disclosed |
| CN-1330647-A | 4-alkenyl (and alkynyl) oxindoles as inhibitors of cell cycle protein dependent kinases, in particular CDK2 | HOFFMANN LA ROCHE (CH) | 2002-01-09 | — | — | CN | disclosed |
| US-20010056081-A1 | Treatment of cerebrovascular disease | MEDICURE INTERNATIONAL INC. (CA) | 2001-12-27 | — | — | US | disclosed |
| CN-1075073-C | Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials | UPJOHN CO (US) | 2001-11-21 | — | — | CN | disclosed |
| WO-2001083484-A1 | PYRANO, PIPERIDINO, AND THIOPYRANO COMPOUNDS AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2001-11-08 | — | — | WO | disclosed |
| WO-2001083480-A2 | DIHYDROPYRIDINE COMPOUNDS AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2001-11-08 | — | — | WO | disclosed |
| US-6313153-B1 | ADMINISTERING PYRIDYLACRYLAMIDE COMPOUND FOR THERAPY OF NEPHRITIS | TSUMURA & CO. (JP) | 2001-11-06 | — | — | US | disclosed |
| US-20010036950-A1 | Potassium channel openers | CARROLL WILLIAM A (US) | 2001-11-01 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-1148053-A1 | 2H-PHTHALAZIN-1-ONE DERIVATIVES AND DRUGS COMPRISING THESE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-6303793-B1 | INTERMEDIATES FOR CYCLIN-DEPENDENT KINASE INHIBITORS | HOFFMANN-LA ROCHE INC. | 2001-10-16 | — | — | US | disclosed |
| WO-2001072309-A2 | TREATMENT OF CEREBROVASCULAR DISEASE | MEDICURE INTERNATIONAL INC. (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001070275-A2 | POLYGLUTAMIC ACID-CAMPTOTHECIN CONJUGATES AND METHODS OF PREPARATION | CELL THERAPEUTICS, INC. (US) | 2001-09-27 | — | — | WO | disclosed |
| US-20010025041-A1 | Amidino protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2001-09-27 | — | — | US | disclosed |
| WO-2001064692-A1 | CARDIOPROTECTIVE PHOSPHONATES AND MALONATES | MEDICURE INTERNATIONAL INC. (BB) | 2001-09-07 | — | — | WO | disclosed |
| EP-0807112-B1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-09-05 | — | — | EP | disclosed |
| US-6281206-B1 | AMIDINO AND BENZAMIDINO COMPOUNDS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2001-08-28 | — | — | US | disclosed |
| EP-1118616-A1 | Process for the production of 5'-nor-anhydrovinblastine ditartrate from plants of genus catharanthus | Eriochem, S.A. (AR) | 2001-07-25 | — | — | EP | disclosed |
| US-6265417-B1 | MUSCLE RELAXANTS | ABBOTT LABORATORIES | 2001-07-24 | — | — | US | disclosed |
| US-6262075-B1 | Piperidone tachykinin antagonists | PFIZER INC | 2001-07-17 | — | — | US | disclosed |
| US-6262042-B1 | EXHIBIT POTENT ANTIPROGESTATIONAL ACTIVITY | RESEARCH TRIANGLE INSTITUTE | 2001-07-17 | — | — | US | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |
| US-6252086-B1 | CYCLIN-DEPENDENT KINASES INHIBITORS; ANTICANCER AGENTS | HOFFMANN-LA ROCHE INC. | 2001-06-26 | — | — | US | disclosed |
| US-6225302-B1 | Amidino protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2001-05-01 | — | — | US | disclosed |
| EP-1082338-A1 | 17 BETA-NITRO-11 BETA-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES | RESEARCH TRIANGLE INSTITUTE (US) | 2001-03-14 | — | — | EP | disclosed |
| EP-1082337-A1 | 17 BETA-AMINO AND HYDROXYLAMINO-11 BETA-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES | RESEARCH TRIANGLE INSTITUTE (US) | 2001-03-14 | — | — | EP | disclosed |
| US-6169102-B1 | ANTI-HELICOBACTER PYLORI AGENT COMPRISING AN OXAZOLIN-4-ONE DERIVATIVE USEFUL AS A THERAPEUTIC AGENT FOR GASTRIC AND DUODENAL ULCER | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| WO-2000078768-A1 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000072849-A1 | NOVEL EPIDERMAL GROWTH FACTOR RECEPTOR-BINDING COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2000-12-07 | — | — | WO | disclosed |
| US-6133315-A | ADMINISTERING TO TREAT PANCREATITIS, THROMBOSIS, ISCHEMIA, STROKE, RESTENOSIS, EMPHYSEMA OR INFLAMMATION IN A MAMMAL; COMPOUNDS SUCH AS 2-CHLOROBENZENESULFONIC ACID 3-(3-AMIDINOPROPOXY)-5-METHYLPHENYL ESTER HYDROCHLORIDE | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| EP-1043317-A1 | NOVEL PYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Kowa Co., Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |
| EP-0831100-B1 | NOVEL PEPTIDE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2000-10-11 | — | — | EP | disclosed |
| EP-1040097-A1 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2000-10-04 | — | — | EP | disclosed |
| US-6126917-A | RADIOLABELED COMPOUND | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2000-10-03 | — | — | US | disclosed |
| US-6127548-A | PREPARING OPTIONALLY SUBSTITUED 3H-IMIDAZOLE-4-CARBALDEHYDE BY PROTECTING THE 3-AMINO GROUP, THEN FORMYLATING IN PRESENCE OF AN ORGANOMETALLIC COMPOUND AND ELECTROPHILE WITH FORMYL LEAVING GROUP, DEPROTECTING WITH ACID OR STRONG BASE | LONZA AG (CH) | 2000-10-03 | — | — | US | disclosed |
| US-6124431-A | ANTICANCER OR ANTITUMOR AGENT | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-09-26 | — | — | US | disclosed |
| US-6124334-A | A BACTERICIDE TREATING INFECTIONS CAUSED BY GRAM-POSITIVE AEROBIC BACTERIA SUCH AS STAPHYLOCOCCUS, STREPTOCOCCUS AND ENTEROCOCCUS AS WELL AS ANAEROBIC ORGANISMS SUCH AS BACTEROIDES AND CLOSTRIDIUM AND MYCOBACTERIDIUM | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| EP-0763524-B1 | Urea and amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prophylactic use | SANKYO CO (JP) | 2000-08-23 | — | — | EP | disclosed |
| WO-2000008202-A9 | 3-METHYLIDENYL-2-INDOLINONE MODULATORS OF PROTEIN KINASE | SUGEN INC (US) | 2000-07-27 | — | — | WO | disclosed |
| US-6093707-A | A HORMONE INHIBITOR EXHIBITING POTENT ANTIPROGESTATIONAL ACTIVITY | RESEARCH TRIANGLE INSTITUTE (US) | 2000-07-25 | — | — | US | disclosed |
| EP-0745073-B1 | 5-SUBSTITUTED DERIVATIVES OF MYCOPHENOLIC ACID | SYNTEX INC (US) | 2000-07-12 | — | — | EP | disclosed |
| EP-1000935-A1 | PYRIDYLACRYLAMIDE DERIVATIVES AND NEPHRITIS REMEDIES AND TGF-$g(b) INHIBITORS CONTAINING THE SAME | TSUMURA & CO. (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-6040339-A | TREATMENT AND PROPHYLAXIS OF HYPERCHOLESTEREMIA OR ARTERIOSCLEROSIS IN A MAMMAL | SANKYO COMPANY, LIMITED (JP) | 2000-03-21 | — | — | US | disclosed |
| US-6034127-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-03-07 | — | — | US | disclosed |
| WO-2000008202-A2 | 3-METHYLIDENYL-2-INDOLINONE MODULATORS OF PROTEIN KINASE | SUGEN, INC. (US) | 2000-02-17 | — | — | WO | disclosed |
| US-6025472-A | PEPTIDE ALDEHYDES WHICH ARE POTENT INHIBITORS OF FACTOR XA, USEFUL AS THERAPEUTIC AGENTS FOR DISEASE STATES IN MAMMALS CHARACTERIZED BY ABNORMAL THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 2000-02-15 | — | — | US | disclosed |
| EP-0973784-A1 | PREPARATION OF TERTIARY PHOSPHINES VIA NICKEL-CATALYZED CROSS COUPLING | NSC Technologies LLC (US) | 2000-01-26 | — | — | EP | disclosed |
| US-6015805-A | POTENT ANTIPROGESTATIONAL ACTIVITY AND ARE USEFUL IN THE TREATMENT OF FIBROIDS, ENDOMETRIOSIS, CERVICAL RIPENING PRIOR TO DELIVERY, HORMONE REPLACEMENT THERAPY AND IN THE CONTROL OF FERTILITY. | RESEARCH TRIANGLE RESEARCH NORTH CAROLINA (US) | 2000-01-18 | — | — | US | disclosed |
| US-6013654-A | Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac diseases | PHARMACIA & UPJOHN COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| US-6004934-A | ANTITUMOR AND ANTICARCINOGENIC AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1999-12-21 | — | — | US | disclosed |
| WO-1999063942-A2 | ISOLATION AND STRUCTURAL ELUCIDATION OF THE HUMAN CANCER CELL GROWTH INHIBITORY COMPOUND DENOMINATED 'AGELAGALASTATIN' | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1999-12-16 | — | — | WO | disclosed |
| WO-1999062929-A1 | 17β-NITRO-11β-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES | RESEARCH TRIANGLE INSTITUTE (US) | 1999-12-09 | — | — | WO | disclosed |
| WO-1999062928-A1 | 17β-AMINO AND HYDROXYLAMINO-11β-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES | RESEARCH TRIANGLE INSTITUTE (US) | 1999-12-09 | — | — | WO | disclosed |
| CN-1237963-A | Quinoline derivatives inhibiting the action of growth factors such as VEGF | ZENECA LTD (GB) | 1999-12-08 | — | — | CN | disclosed |
| US-5962444-A | HORMONE INHIBITOR; HORMONE REPLACEMENT THERAPY | RESEARCH TRIANGLE INSTITUTE (US) | 1999-10-05 | — | — | US | disclosed |
| US-5955491-A | ADMINISTERING CATHEPSIN L INHIBITOR AND BONE RESORPTION INHIBITOR CONTAINING AN ALCOHOL OR ALDEHYDE DERIVATIVE, OR SALT THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| EP-0929526-A1 | QINOLINE DERIVATIVES INHIBITING THE EFFECT OF GROWTH FACTORS SUCH AS VEGF | ZENECA LIMITED (GB) | 1999-07-21 | — | — | EP | disclosed |
| WO-1999031059-A1 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 1999-06-24 | — | — | WO | disclosed |
| EP-0923577-A2 | OXAZOLONE DERIVATIVES AND THEIR USE AS ANTI-HELICOBACTER PYLORI AGENT | Takeda Chemical Industries, Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5912246-A | Imidazo 1,2-a!pyridines for the treatment of CNS and cardiac diseases | PHARMACIA & UPJOHN COMPANY (US) | 1999-06-15 | — | — | US | disclosed |
| US-5910504-A | BACTERICIDES TREATING INFECTIONS | PHARMACIA & UPJOHN (US) | 1999-06-08 | — | — | US | disclosed |
| US-5902904-A | Method for preparation of tertiary phosphines via nickel-catalyzed cross coupling | MONSANTO COMPANY (US) | 1999-05-11 | — | — | US | disclosed |
| EP-0883405-A4 | AMIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-04-28 | — | — | EP | disclosed |
| US-5880147-A | Amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prohylactic use | SANKYO COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| US-5874628-A | Method for preparation of tertiary phosphines via nickel-catalyzed cross coupling | MONSANTO COMPANY (US) | 1999-02-23 | — | — | US | disclosed |
| US-5869454-A | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0888337-A1 | PIPERIDONE TACHYKININ ANTAGONISTS | Pfizer Research and Development Company, N.V./S.A. (IE) | 1999-01-07 | — | — | EP | disclosed |
| EP-0883405-A1 | AMIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-12-16 | — | — | EP | disclosed |
| US-5843452-A | Immunotherapy composition and method | PHARMAGENESIS, INC. (US) | 1998-12-01 | — | — | US | disclosed |
| US-5840699-A | ANTITUMOR AGENTS | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| WO-1998042716-A1 | PREPARATION OF TERTIARY PHOSPHINES VIA NICKEL-CATALYZED CROSS COUPLING | NSC TECHNOLOGIES LLC (US) | 1998-10-01 | — | — | WO | disclosed |
| US-5808059-A | CHROMATOGRAPHY; ELECTROPHORESIS | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 1998-09-15 | — | — | US | disclosed |
| US-5801222-A | Isolation and structure of the human cancer cell growth inhibitory cyclic octapeptides phakellistatin 10 and 11 | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1998-09-01 | — | — | US | disclosed |
| US-5786461-A | Peptide nucleic acids having amino acid side chains | BUCHARDT OLE (DK) | 1998-07-28 | — | — | US | disclosed |
| US-5767237-A | ANTITUMOR AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5759550-A | Method for suppressing xenograft rejection | PHARMAGENESIS, INC. (US) | 1998-06-02 | — | — | US | disclosed |
| CN-1182434-A | Novel peptide derivatives | TEIKOKU HORMONE MFG CO LTD (JP) | 1998-05-20 | — | — | CN | disclosed |
| US-5750709-A | DEWAXING, DEFATTING, DEOILING SOURCE MATERIAL BY SUBJECTING TO FIRST AND SECOND SUPERCRITICAL OR CRITICAL FLUIDS, SEPARATING | APHIOS CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |
| EP-0722448-A4 | O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO INC (US) | 1998-04-29 | — | — | EP | disclosed |
| US-5744302-A | USING A PORPHYRIN; COMPLEXING | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-04-28 | — | — | US | disclosed |
| US-5736336-A | Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility | BUCHARDT OLE (DK) | 1998-04-07 | — | — | US | disclosed |
| WO-1998013350-A1 | QINOLINE DERIVATIVES INHIBITING THE EFFECT OF GROWTH FACTORS SUCH AS VEGF | ZENECA LIMITED (GB) | 1998-04-02 | — | — | WO | disclosed |
| EP-0831100-A1 | NOVEL PEPTIDE DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1998-03-25 | — | — | EP | disclosed |
| US-5719262-A | BIND COMPLEMENTARY DNA AND RNA STRANDS MORE STRONGLY | BUCHARDT OLE (DK) | 1998-02-17 | — | — | US | disclosed |
| US-5716980-A | PROPHYLACTIC, THERAPY FOR OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| CN-1172484-A | Phenyl oxazolidinone antibacterial agents substituted with heteroaromatic rings | UPJOHN CO (US) | 1998-02-04 | — | — | CN | disclosed |
| US-5714331-A | INCORPORATING AN AMINOALKYL SIDE CHAIN INTO THE PNA'S WHICH BIND TO COMPLEMENTARY NUCLEOBASE SEQUENCES MORE TIGHTLY TO FORM ?DUPLEXES?; VIRICIDES; ANTICARCINOGENIC AGENTS; ENZYME INHIBITORS | EXXON CHEMICAL PATENT INC. | 1998-02-03 | — | — | US | disclosed |
| CN-1171394-A | New urea derivatives, their preparation and their therapeutic and prophylactic use | SANKYO CO (JP) | 1998-01-28 | — | — | CN | disclosed |
| WO-1997049703-A2 | OXAZOLONE DERIVATIVES AND THEIR USE AS ANTI-HELICOBACTER PYLORI AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-31 | — | — | WO | disclosed |
| EP-0536896-B1 | Imidazolidyl macrolides having immunosuppressive activity | MERCK & CO INC (US) | 1997-12-17 | — | — | EP | disclosed |
| US-5696231-A | ANTICOAGULANTS; CARDIOVASCULAR DISORDERS | CORVAS INTERNATIONAL, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| EP-0809642-A1 | IMIDAZO 1,2-A]PYRIDINES FOR THE TREATMENT OF CNS AND CARDIAC DISEASES | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-03 | — | — | EP | disclosed |
| EP-0689537-B1 | METHOD AND APPARATUS FOR EXTRACTING TAXOL FROM SOURCE MATERIALS | APHIOS CORP (US) | 1997-12-03 | — | — | EP | disclosed |
| US-5693648-A | TREATMENT OF AUTOIMMUNE DISEASES, INFECTIOUS DISEASES, PREVENTING REJECTION OF ORGAN TRANSPLANTS | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |
| US-5691366-A | UNSATURATED NITRO OXIME FORMED BY REACTION OF DINITROGEN TRIOXIDE WITH DIOLEFIN ETHER, SULFIDE OR AMINE TO BE USED AS VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5684198-A | N-ARYL-2-HYDROXYPROPANAMIDES | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1997-11-04 | — | — | US | disclosed |
| US-5681829-A | Class of phosphocholine derivatives having antifungal activity | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-10-28 | — | — | US | disclosed |
| EP-0801654-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES AS INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5672490-A | PROMOTING THE SPLITTING DNA BY MIXING WITH A SAPPHYRIN-EDTA CONJUGATE COMPOUND | THE UNIVERSITY OF TEXAS BOARD OF REGENTS (US) | 1997-09-30 | — | — | US | disclosed |
| CN-1159190-A | Bioactive acetogenins and derivatives | PURDUE RESEARCH FOUNDATION (US) | 1997-09-10 | — | — | CN | disclosed |
| WO-1997027185-A1 | PIPERIDONE TACHYKININ ANTAGONISTS | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-07-31 | — | — | WO | disclosed |
| WO-1997024135-A1 | AMIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | disclosed |
| US-5646246-A | ANTITUMOR AGENTS | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1997-07-08 | — | — | US | disclosed |
| US-5639781-A | PREVENT REABSORPTION OF BONE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| US-5633279-A | 5-substituted derivatives of mycophenolic acid | SYNTEX (U.S.A.) INC. (US) | 1997-05-27 | — | — | US | disclosed |
| EP-0763524-A1 | Urea and amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prophylactic use | SANKYO COMPANY LIMITED (JP) | 1997-03-19 | — | — | EP | disclosed |
| US-5597921-A | ANTITUMOR AGENTS, TREATMENT OF LEUKEMIA | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0745073-A1 | 5-SUBSTITUTED DERIVATIVES OF MYCOPHENOLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1996-12-04 | — | — | EP | disclosed |
| US-5567735-A | CELL POTASSIUM CHANNEL MODULATOR FOR TREATING ASTHMA | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-10-22 | — | — | US | disclosed |
| US-5565477-A | TREATMENT OF URINARY INCONTINENCE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-10-15 | — | — | US | disclosed |
| US-5565465-A | TREATMENT OF URINARY INCONTINENCE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-10-15 | — | — | US | disclosed |
| US-5565560-A | TREATING AUTOIMMUNE DISEASES, PREVENTING TRANSPLANT REJECTION | MERCK & CO., INC. (US) | 1996-10-15 | — | — | US | disclosed |
| WO-1996025414-A1 | IMIDAZO[1,2-A]PYRIDINES FOR THE TREATMENT OF CNS AND CARDIAC DISEASES | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-22 | — | — | WO | disclosed |
| WO-1996023788-A1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA + UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |
| EP-0722448-A1 | O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO. INC. (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5532248-A | O-aryl,O-alkyl, and O-alkenyl-macrolides having immunosuppressive activity | MERCK CO., INC. (US) | 1996-07-02 | — | — | US | disclosed |
| WO-1996019493-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES AS INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5530123-A | ANTIVIRAL AND CHEMOTHERAPEUTICAL AGENT FOR CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-06-25 | — | — | US | disclosed |
| US-5519050-A | Isolation and structural elucidation of halistatin 3 | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1996-05-21 | — | — | US | disclosed |
| US-5510251-A | AEROBICALLY FERMENTING STREPTOMYCES CYANEOGRISEUS NONCYANOGENUS MICROORGANISM OR MUTANT, IN A NEUTRIENT MEDIUM TO PRODUCE THE ANTIBIOTIC | AMERICAN CYANAMID COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0663816-A4 | NOVEL CLASS OF PHOSPHOCHOLINE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY. | SHAMAN PHARMACEURICALS INC (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0524781-B1 | Therapeutic amides | ZENECA LTD (GB) | 1996-03-27 | — | — | EP | disclosed |
| US-5498728-A | OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| US-5495023-A | VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| US-5494893-A | ANTITUMOR AGENTS | ARIZONA BOARD OF REGENTS, A BODY CORPORATE ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1996-02-27 | — | — | US | disclosed |
| US-5493030-A | CHEMICAL INTERMEDIATES | SYNTEX (U.S.A.) INC. (US) | 1996-02-20 | — | — | US | disclosed |
| US-5474999-A | Useful in treatment of urinary incontinence | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-12-12 | — | — | US | disclosed |
| US-5468772-A | Tripterinin compound and method | PHARMAGENESIS, INC. (US) | 1995-11-21 | — | — | US | disclosed |
| US-5457195-A | Sapphyrin derivatives and conjugates | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-10-10 | — | — | US | disclosed |
| EP-0388528-B1 | Carboximidamide derivatives | KIRIN BREWERY (JP) | 1995-09-27 | — | — | EP | disclosed |
| CN-1107363-A | Alcohol or aldehyde derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-30 | — | — | CN | disclosed |
| WO-1995022538-A1 | 5-SUBSTITUTED DERIVATIVES OF MYCOPHENOLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1995-08-24 | — | — | WO | disclosed |
| US-5439934-A | Antibiotic LL-F28249 and derivatives for control and prevention of plant insect and nematode infestations and also infections in mammals; fermentation of Streptomyces cyaneogriseus ssp. noncyanogenus | AMERICAN CYANAMID COMPANY (US) | 1995-08-08 | — | — | US | disclosed |
| US-5440055-A | Dewaxing source material with critical or near critical fluid, extracting with mixture of critical or near critical fluid and polar cosolvent, separating impurities by chromatography | APHIOS CORPORATION (US) | 1995-08-08 | — | — | US | disclosed |
| EP-0663816-A1 | NOVEL CLASS OF PHOSPHOCHOLINE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY | SHAMAN PHARMACEURICALS, INC. (US) | 1995-07-26 | — | — | EP | disclosed |
| US-5418168-A | Antibiotics | AMERICAN CYANAMID COMPANY (US) | 1995-05-23 | — | — | US | disclosed |
| WO-1995013082-A1 | IMMUNOTHERAPY COMPOSITION AND METHOD | PHARMAGENESIS, INC. (US) | 1995-05-18 | — | — | WO | disclosed |
| US-5409953-A | Administering to treat lymphocytic leukemia | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1995-04-25 | — | — | US | disclosed |
| WO-1995009857-A1 | O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |
| US-5403572-A | Macrocyclic polyaza compounds containing 5 or 6 membered rings, process for producing them and pharmaceutical media containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-04-04 | — | — | US | disclosed |
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| US-5382598-A | Therapeutic amides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-01-17 | — | — | US | disclosed |
| WO-1994026692-A1 | BICYCLIC AMIDE DERIVATIVES AND THEIR USE AS MUSCLE RELAXANTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-24 | — | — | WO | disclosed |
| WO-1994026265-A1 | 16-HYDROXYTRIPTOLIDE COMPOSITION AND METHOD FOR IMMUNOTHERAPY | PHARMAGENESIS, INC. (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5366880-A | Cyclic lipopeptides | MERCK & CO., INC. (US) | 1994-11-22 | — | — | US | disclosed |
| EP-0178048-B1 | Bryostatins | UNIV ARIZONA STATE (US) | 1994-10-12 | — | — | EP | disclosed |
| WO-1994020488-A1 | TRIPTERININ COMPOUND AND METHOD | PHARMAGENESIS, INC. (US) | 1994-09-15 | — | — | WO | disclosed |
| EP-0494515-B1 | Antibiotic cyclic hexapeptide | MERCK & CO INC (US) | 1994-09-14 | — | — | EP | disclosed |
| US-5344925-A | Autoimmune diseases; infections; organ transplants | MERCK & CO., INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0612315-A1 | NITRO COMPOUNDS HAVING VASODILATOR ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0611756-A2 | Alcohol or aldehyde derivatives as cathepsin L inhibitor and bone resorption inhibitor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-24 | — | — | EP | disclosed |
| US-5334371-A | Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | disclosed |
| EP-0405997-B1 | Antibiotic agent | MERCK & CO INC (US) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994008563-A9 | NOVEL CLASS OF PHOSPHOCHOLINE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY | — | 1994-06-09 | — | — | WO | disclosed |
| US-5317030-A | Antibiotic LL F28249 derivatives | AMERICAN CYANAMID COMPANY (US) | 1994-05-31 | — | — | US | disclosed |
| WO-1994008563-A1 | NOVEL CLASS OF PHOSPHOCHOLINE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY | SHAMAN PHARMACEUTICAL, INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| WO-1994009003-A1 | SAPPHYRIN DERIVATIVES, CONJUGATES AND POLYMERS THEREOF AND EXPANDED PORPHYRIN CHROMATOGRAPHIC SUPPORTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5306708-A | Fungicides | MERCK & CO., INC. (US) | 1994-04-26 | — | — | US | disclosed |
| US-5272164-A | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-12-21 | — | — | US | disclosed |
| US-5272163-A | Therapeutic amides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-21 | — | — | US | disclosed |
| EP-0311193-B1 | Antifungal fermentation product | MERCK & CO INC (US) | 1993-12-01 | — | — | EP | disclosed |
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-5250678-A | For autoimmune, infectious diseases, organ transplant rejection; skin diseases, antiinflammatory agents | MERCK & CO., INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-5247076-A | IMIDAZOLIDYL MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO., INC. (US) | 1993-09-21 | — | — | US | disclosed |
| EP-0399685-B1 | ISOLATION AND STRUCTURAL ELUCIDATION OF THE CYTOSTATIC LINEAR DEPSIPEPTIDES DOLASTATIN 13 AND DEHYDRODOLASTATIN 13 | ARIZONA BOARD OF REGENTS, ARIZONA STATE UNIVERSITY (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0398558-B1 | ISOLATION AND STRUCTUAL ELUCIDATION OF THE CYTOSTATIC LINEAR DEPSIPEPTIDE DOLASTATIN 15 | ARIZONA BOARD OF REGENTS (US) | 1993-07-28 | — | — | EP | disclosed |
| US-5223508-A | Hypotensive agents, vasodilators | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010097-A1 | NITRO COMPOUNDS HAVING VASODILATOR ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-27 | — | — | WO | disclosed |
| EP-0536896-A1 | Imidazolidyl macrolides having immunosuppressive activity | MERCK & CO. INC. (US) | 1993-04-14 | — | — | EP | disclosed |
| US-5202309-A | Fungicide; treating pneumocystis carinii infections | MERCK & CO., INC. (US) | 1993-04-13 | — | — | US | disclosed |
| US-5198464-A | Antibiotic LL-F28249 as insecticides | AMERICAN CYANAMID COMPANY (US) | 1993-03-30 | — | — | US | disclosed |
| WO-1993005059-A1 | IMIDAZOLIDYL MACROLIDES | MERCK & CO., INC. (US) | 1993-03-18 | — | — | WO | disclosed |
| US-5194377-A | Fungicides and antipneumocystis | MERCK & CO., INC. (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0359529-B1 | METHOD FOR THE CONTROL OF PNEUMOCYSTIS CARINII | MERCK & CO. INC. (US) | 1993-03-03 | — | — | EP | disclosed |
| EP-0524781-A1 | Therapeutic amides | ZENECA LIMITED (GB) | 1993-01-27 | — | — | EP | disclosed |
| US-5169956-A | Isolated from Streptomyces strain; anthelmintics, miticides, parasiticides, nematocides | AMERICAN CYANAMID COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| US-5166347-A | Hypotensive agents, cardiovascular disorders, antiischemic agents and anticoagulants | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-11-24 | — | — | US | disclosed |
| US-5166135-A | Administering cyclohexapeptide antibiotic; AIDS | MERCK & COMPANY, INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5164389-A | ANTHELMINTIC BIOCONVERSION PRODUCTS | MERCK & CO., INC. (US) | 1992-11-17 | — | — | US | disclosed |
| US-5162211-A | Process for producing a cyclic lipopeptide employing zalerion arboricola | MERCK & CO., INC. (US) | 1992-11-10 | — | — | US | disclosed |
| US-5158970-A | Prolylendopeplidase inhibitors; antiamnesia | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0337765-B1 | ACYLSULFONAMIDE DERIVATIVES OF ALPHA-CARBOCYCLYLTOLUIC ACIDS USED AS LEUKOTRIENE ANTAGONISTS | ICI AMERICAS INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| US-5151526-A | Adrenergic antagonist | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1992-09-29 | — | — | US | disclosed |
| US-5134123-A | Renin enzyme inhibitors for cardiovascular disorders and high blood pressure | HOFFMAN-LA ROCHE INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0494515-A1 | Antibiotic cyclic hexapeptide | MERCK & CO. INC. (US) | 1992-07-15 | — | — | EP | disclosed |
| EP-0170006-B1 | METHOD AND COMPOSITIONS FOR HELMINTIC, ARTHROPOD ECTOPARASITIC AND ACARIDAL INFECTIONS WITH NOVEL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1992-07-08 | — | — | EP | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |
| US-5106994-A | Antibiotic LL-F28249 | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |
| US-5095038-A | Antiinflammatory, antiallergens | ICI AMERICAS INC. (US) | 1992-03-10 | — | — | US | disclosed |
| US-5075307-A | PARAHERQUAMIDE AND DIHYDROPARAHERQUAMIDE AS ANTIHELMINTHIC AGENTS | MERCK & CO., INC. (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0448355-A2 | Antibiotic agents | MERCK & CO. INC. (US) | 1991-09-25 | — | — | EP | disclosed |
| EP-0448301-A2 | Antibiotic agents | MERCK & CO. INC. (US) | 1991-09-25 | — | — | EP | disclosed |
| US-5049546-A | Fungicides | MERCK & CO., INC. (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0295729-B1 | INTRAMOLECULAR NUCLEOPHILIC DISPLACEMENT COMPOUND AND USE IN PHOTOGRAPHY | AGFA-GEVAERT N.V. (BE) | 1991-09-04 | — | — | EP | disclosed |
| US-5045537-A | Treating Diseases Caused by Retroviruses | SANDOZ LTD. (CH) | 1991-09-03 | — | — | US | disclosed |
| US-5043459-A | Saccharoascorbic acid derivatives and production thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0276051-B1 | ANTINEOPLASTIC COMPOUNDS | ARIZONA BOARD OF REGENTS (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0435887-A1 | RENIN INHIBITORY PEPTIDES CONTAINING MALEAMIDE SUBSTITUENTS | THE UPJOHN COMPANY (US) | 1991-07-10 | — | — | EP | disclosed |
| US-5021403-A | Fungicides; side effect reduction | MERCK & CO., INC. (US) | 1991-06-04 | — | — | US | disclosed |
| US-5021341-A | Efficiency | MERCK & CO., INC. (US) | 1991-06-04 | — | — | US | disclosed |
| US-4996305-A | Process for producing the antibiotic and antitumor agents LL-E33288.epsilon.ε-Br | AMERICAN CYANAMID COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| US-4986988-A | ANTITUMOR AGENTS | ARIZONA BOARD OF REGENTS (US) | 1991-01-22 | — | — | US | disclosed |
| EP-0405997-A1 | Antibiotic agent | MERCK & CO. INC. (US) | 1991-01-02 | — | — | EP | disclosed |
| EP-0405998-A1 | Antibiotic agents | MERCK & CO. INC. (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4978656-A | PARASITICIDES | MERCK & CO., INC. (US) | 1990-12-18 | — | — | US | disclosed |
| US-4978744-A | Synthesis of dolastatin 10 | ARIZONA BOARD OF REGENTS (US) | 1990-12-18 | — | — | US | disclosed |
| EP-0399685-A1 | Isolation and structural elucidation of the cytostatic linear depsipeptides dolastatin 13 and dehydrodolastatin 13 | ARIZONA BOARD OF REGENTS, ARIZONA STATE UNIVERSITY (US) | 1990-11-28 | — | — | EP | disclosed |
| EP-0398558-A1 | Isolation and structual elucidation of the cytostatic linear depsipeptide dolastatin 15 | ARIZONA BOARD OF REGENTS (US) | 1990-11-22 | — | — | EP | disclosed |
| US-4968608-A | CYCLIC PEPTIDE ANTIBIOTIC FROM ZALERION | MERCK & CO., INC. (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0390532-A2 | Anthelmintic bioconversion products | MERCK & CO. INC. (US) | 1990-10-03 | — | — | EP | disclosed |
| EP-0388528-A2 | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1990-09-26 | — | — | EP | disclosed |
| EP-0384341-A2 | New proline derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| CN-1044655-A | Saccharoascorbic acid derivatives and preparation method thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-08-15 | — | — | CN | disclosed |
| EP-0381472-A1 | Saccharoascorbic acid derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-08-08 | — | — | EP | disclosed |
| US-4931352-A | Antifungal fermentation product | MERCK & CO., INC. (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0364493-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1990003389-A1 | RENIN INHIBITORY PEPTIDES CONTAINING MALEAMIDE SUBSTITUENTS | THE UPJOHN COMPANY (US) | 1990-04-05 | — | — | WO | disclosed |
| US-4912028-A | Alkali permeable hydrophilic colloid | AGFA-GEVAERT, N.V. (BE) | 1990-03-27 | — | — | US | disclosed |
| EP-0359529-A1 | Method for the control of pneumocystis carinii | MERCK & CO. INC. (US) | 1990-03-21 | — | — | EP | disclosed |
| EP-0354615-A1 | Synthetic derivative of paraherquamide | MERCK & CO. INC. (US) | 1990-02-14 | — | — | EP | disclosed |
| US-4898872-A | Imidazo[4,5-b]pyridyl quinolone cardiac stimulants | PFIZER INC. (US) | 1990-02-06 | — | — | US | disclosed |
| US-4892873-A | MUSCLE RELAXANTS, ANTIEPILEPTIC, AN XIOLYTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4879278-A | ANTINEOPLASTIC | ARIZONA BOARD OF REGENTS (US) | 1989-11-07 | — | — | US | disclosed |
| EP-0337765-A2 | Acylsulfonamide derivatives of alpha-carbocyclyltoluic acids used as leukotriene antagonists | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |
| US-4873247-A | Derivatives of paraherquamide isolated from a fermentation broth active as antiparasitic agents | MERCK & CO. INC. | 1989-10-10 | — | — | US | disclosed |
| US-4873245-A | ANTICARCINOGENIC AGENTS; LEUKEMIA | ARIZONA BOARD OF REGENTS (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0334421-A1 | Antifungal fermentation product and derivatives and compositions thereof | MERCK & CO. INC. (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4869901-A | FERMENTATION PRODUCT OF STREPTOMYCES | AMERICAN CYANAMID COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| WO-1989008655-A1 | ISOLATION AND STRUCTURAL ELUCIDATION OF CEPHALOSTATINS 1-4 | ARIZONA BOARD OF REGENTS (US) | 1989-09-21 | — | — | WO | disclosed |
| EP-0330874-A2 | Antibacterial and antitumor agents LL-E33288 epsilon-I and LL-E33288-epsilonBr, with processes and intermediates for producing said agents | AMERICAN CYANAMID COMPANY (US) | 1989-09-06 | — | — | EP | disclosed |
| US-4847284-A | PYRROLIDINOL ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0322937-A2 | Derivatives of paraherquamide isolated from a fermentation broth active as antiparasitic agents | MERCK & CO. INC. (US) | 1989-07-05 | — | — | EP | disclosed |
| US-4843082-A | 1,2,3,4-tetrahydro-8-quinolinol derivatives and anti-allergic use thereof | E. R. SQUIBB & SONS, INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0311194-A2 | Process for antifungal fermentation product and culture | MERCK & CO. INC. (US) | 1989-04-12 | — | — | EP | disclosed |
| EP-0311193-A2 | Antifungal fermentation product | MERCK & CO. INC. (US) | 1989-04-12 | — | — | EP | disclosed |
| US-4816444-A | ANTITUMOR AGENTS | ARIZONA BOARD OF REGENTS, ARIZONA STATE UNIVERSITY (US) | 1989-03-28 | — | — | US | disclosed |
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |
| WO-1989001488-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1989-02-23 | — | — | WO | disclosed |
| US-4806565-A | 5-(1-HYDROXY-2,4,6-HEPTATRIYNYL)-2-OXO-1,3-DIOXOLANES | MERCK & CO., INC. (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0301742-A2 | Paraherquamide and dihydroparaherquamide as antiparasitic agents | MERCK & CO. INC. (US) | 1989-02-01 | — | — | EP | disclosed |
| EP-0295729-A1 | Intramolecular nucleophilic displacement compound and use in photography | AGFA-GEVAERT N.V. (BE) | 1988-12-21 | — | — | EP | disclosed |
| EP-0293133-A2 | Microorganisms and processes for the manufacture of antifungal tri-yne carbonates | MERCK & CO. INC. (US) | 1988-11-30 | — | — | EP | disclosed |
| EP-0290153-A1 | Heterobicyclic quinolone derivatives | Pfizer Limited (GB) | 1988-11-09 | — | — | EP | disclosed |
| US-4780311-A | Antihypercholesterolemic tri-yne carbonates | MERCK & CO., INC. (US) | 1988-10-25 | — | — | US | disclosed |
| US-4767765-A | ANXIOLYTIC OR ANTIEPILEPTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0276051-A2 | Antineoplastic compounds | ARIZONA BOARD OF REGENTS (US) | 1988-07-27 | — | — | EP | disclosed |
| US-4751237-A | ENZYME INHIBITORS | MERCK & CO., INC. (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | disclosed |
| EP-0223974-A1 | N-Substituted-N-[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)-phenyl]alkanamides, carbamates and ureas | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |
| US-4656026-A | DIAGNOSING MENTAL, MOVEMENT, SEIZURE DISORDERS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1987-04-07 | — | — | US | disclosed |
| US-4654343-A | USEFUL AS ANXIOLYTIC OR ANTIEPILEPTIC AGENTS AS WELL AS SEDATIVE-HYPNOTIC AND SKELETAL MUSCLE RELAXANT AGENTS | AMERICAN CYANAMID COMPANY (US) | 1987-03-31 | — | — | US | disclosed |
| US-4611066-A | ANTITUMOR AGENTS, VIRICIDES | ARIZONA STATE UNIVERSITY (US) | 1986-09-09 | — | — | US | disclosed |
| US-4606753-A | PLANT GROWTH REGULATORS | SHELL OIL COMPANY (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0077536-B1 | 2'-SUBSTITUTED-SPIRO(BENZOFURAN-2(3H),1'-CYCLOALKANES), A PROCESS FOR PREPARING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-07-16 | — | — | EP | disclosed |
| US-4594435-A | ANTIDEPRESSANTS; ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1986-06-10 | — | — | US | disclosed |
| EP-0178048-A1 | Bryostatins | ARIZONA BOARD OF REGENTS, ARIZONA STATE UNIVERSITY (US) | 1986-04-16 | — | — | EP | disclosed |
| EP-0170006-A2 | Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents | AMERICAN CYANAMID COMPANY (US) | 1986-02-05 | — | — | EP | disclosed |
| US-4517311-A | 2'-Substituted-spiro[benzofuran-2(3H),1'-cycloalkanes] and their analgesic and anti-depressant compositions | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-05-14 | — | — | US | disclosed |
| US-4510134-A | X 14868A OR LL-23024B | AMERICAN CYANAMID CO. (US) | 1985-04-09 | — | — | US | disclosed |
| US-4509855-A | Dual liquid and gas chromatograph system | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1985-04-09 | — | — | US | disclosed |
| EP-0063858-B1 | LEUKOTRIENE ANALOGUES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | Lilly Industries Limited (GB) | 1985-03-20 | — | — | EP | disclosed |
| US-4470699-A | Micro-column plasma emission liquid chromatograph | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1984-09-11 | — | — | US | disclosed |
| EP-0063858-A1 | Leukotriene analogues, their preparation and use in pharmaceutical compositions | Lilly Industries Limited (GB) | 1982-11-03 | — | — | EP | disclosed |
| US-4301246-A | HYDROXYLATION OF 3-KETO-BISNORCHOLENOL TO 7-HYDROXY-3-KETO-BISNORCHOLENOL | HOFFMANN-LA ROCHE INC. (US) | 1981-11-17 | — | — | US | disclosed |
| US-4254224-A | CULTURED FROM FUNGUS | MERCK & CO., INC. (US) | 1981-03-03 | — | — | US | disclosed |
| US-4230625-A | DISSOLVING GALLSTONES | HOFFMANN-LA ROCHE INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4226856-A | ANTITUMOR AGENTS | UNIVERSITY PATENTS, INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4201771-A | FUNGICIDES | MERCK & CO., INC. (US) | 1980-05-06 | — | — | US | disclosed |
| US-4001402-A | FOR TREATING CARDIAC INSUFFICIENCY | KNOLL A.G. CHEMISCHE FABRIKEN (DT) | 1977-01-04 | — | — | US | disclosed |
| US-4001402-A | FOR TREATING CARDIAC INSUFFICIENCY | KNOLL A.G. CHEMISCHE FABRIKEN (DT) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030211973-A1 | Polyglutamic acid-camptothecin conjugates and methods of preparation | QPCT, DCLRE1A, FOLH1 | TSHR 2812/4885ALDH1A1 2195/4885THRB 4192/4885 |
| US-20030055035-A1 | Pyrano piperidino and thiopyrano compounds and methods of use | KCNJ3, KCNJ6, KCNJ5 | TSHR 2656/4885ALDH1A1 571/4885THRB 1709/4885 |
| US-20120095187-A1 | NOVEL CYANINE COMPOUND FOR LABELING BIOMOLECULE AND PREPARATION METHOD THEREOF | MRPL21, MB, CCNB1 | TSHR 3035/4885ALDH1A1 1684/4885THRB 2236/4885 |
| US-20030199440-A1 | Composition for the treatment of damaged tissue | MMP1, SERPINE1, COL14A1 | TSHR 4346/4885ALDH1A1 2641/4885THRB 2831/4885 |
| US-20060094761-A1 | Dual antiplatelet/anticoagulant pyridoxine analogs | PNPO, PLPBP, PRDX6 | TSHR 1006/4885ALDH1A1 1337/4885THRB 2695/4885 |
| US-20030004173-A1 | Pharmaceutically active compounds | PDE5A, PDE3A, PDE2A | TSHR 3488/4885ALDH1A1 439/4885THRB 3133/4885 |
| US-20210299154-A1 | Senolytic Compositions And Uses Thereof | SENP3, SENP6, SENP1 | TSHR 3671/4885ALDH1A1 1807/4885THRB 4037/4885 |
| US-20020016285-A1 | Polyglutamic acid-camptothecin conjugates and methods of preparation | QPCT, DCLRE1A, FOLH1 | TSHR 2812/4885ALDH1A1 2195/4885THRB 4192/4885 |
| US-11026963-B2 | Senolytic compositions and uses thereof | SENP3, SENP6, SENP1 | TSHR 3671/4885ALDH1A1 1807/4885THRB 4037/4885 |
| US-20110152518-A1 | Cycloalkyl Substituted Pyrimidinediamine Compounds And Their Uses | MKI67, PCNA, TK1 | TSHR 3842/4885ALDH1A1 1807/4885THRB 3174/4885 |
| US-20110003980-A1 | Oligo-Aminosaccharide compound | DDOST, STT3A, STT3B | TSHR 4643/4885ALDH1A1 4209/4885THRB 4458/4885 |
| US-20070208025-A1 | NOVEL PYRIDAZINE DERIVATIVES AND MEDICINES CONTAINING THE SAME AS EFFECTIVE INGREDIENTS | IL1B, IL1R1, TLR1 | TSHR 2938/4885ALDH1A1 626/4885THRB 1909/4885 |
| US-20050267113-A1 | Novel pyridazine derivatives and medicines containing the same as effective ingredients | IL1B, IL1R1, IRAK1 | TSHR 3151/4885ALDH1A1 461/4885THRB 2053/4885 |
| US-20040157838-A1 | Cannabinoid receptor ligands and uses thereof | CNR1, CNR2, GPR18 | TSHR 503/4885ALDH1A1 1683/4885THRB 383/4885 |
| US-20070154572-A1 | Compositions derived from portulaca oleracea l. and methods of using same for modulating blood glucose levels | PNLIP, LIPC, SLC5A1 | TSHR 4796/4885ALDH1A1 1007/4885THRB 4342/4885 |
| US-20090270399-A1 | NOVEL PYRIDAZINE DERIVATIVES AND MEDICINES CONTAINING THE SAME AS EFFECTIVE INGREDIENTS | IL1B, IL1R1, TLR1 | TSHR 2845/4885ALDH1A1 539/4885THRB 1931/4885 |
| US-20030114677-A1 | Cardioprotective phosphonates and malonates | PDXK, PHOSPHO1, PNPO | TSHR 3443/4885ALDH1A1 2080/4885THRB 3219/4885 |
| US-11840531-B2 | CDK8/19 inhibitors | CDK8, CDK9, CDK18 | TSHR 3967/4885ALDH1A1 3487/4885THRB 3252/4885 |
| US-20070135516-A1 | Irciniastatins a and b | IGF1R, IGFBP2, GHRHR | TSHR 692/4885ALDH1A1 4662/4885THRB 276/4885 |
| US-20030181422-A1 | Cardioprotective phosphonates and malonates | PDXK, PHOSPHO1, PNPO | TSHR 3443/4885ALDH1A1 2080/4885THRB 3219/4885 |
| US-20030018033-A1 | Novel dihydroxyhexanoic acid derivatives | HCAR1, HCAR2, SLC27A1 | TSHR 3663/4885ALDH1A1 91/4885THRB 1533/4885 |
| US-20040019210-A1 | Kinase inhibitors | CDK2, CDK1, CDK4 | TSHR 3028/4885ALDH1A1 1779/4885THRB 3243/4885 |
| US-20200016185-A1 | SENOLYTIC COMPOSITIONS AND USES THEREOF | SENP3, SENP6, SENP1 | TSHR 3671/4885ALDH1A1 1807/4885THRB 4037/4885 |
| US-20020065257-A1 | 17beta-amino and hydroxylamino-11beta-arylsteroids and their derivatives having agonist or antagonist hormonal properties | HSD17B11, HSD17B2, CYP17A1 | TSHR 218/4885ALDH1A1 1167/4885THRB 93/4885 |
| US-20050065155-A1 | Novel pyridazine derivatives and medicines containing the same as effective ingredients | IL1B, TLR1, IRAK1 | TSHR 2944/4885ALDH1A1 464/4885THRB 1681/4885 |
| US-20040147516-A1 | Novel pyridazine derivatives and medicines containing the same as effective ingredients | IL1B, IRAK1, TLR1 | TSHR 3237/4885ALDH1A1 391/4885THRB 1977/4885 |
| US-20040087571-A1 | Methods of using CCR1 antagonists as immunomodulatory agents | CCR1, CCR3, CCRL2 | TSHR 1258/4885ALDH1A1 438/4885THRB 2122/4885 |
| US-20080051412-A1 | Stereoisomerically Enriched 3-Aminocarbonyl Bicycloheptene Pyrimidinediamine Compounds and their Uses | MKI67, PCNA, CCNI | TSHR 4647/4885ALDH1A1 705/4885THRB 2964/4885 |
| US-20070167411-A1 | Compositions for treating angina | PNPO, PYGM, PLPBP | TSHR 3843/4885ALDH1A1 1367/4885THRB 3574/4885 |
| US-20070299060-A1 | Cycloalkyl Substituted Pyrimidinediamine Compounds And Their Uses | MKI67, PCNA, TK1 | TSHR 3842/4885ALDH1A1 1807/4885THRB 3174/4885 |
| US-20080311099-A1 | Pyridoxal-5-Phosphate and Related Compounds in Combination With Therapeutic Cardiovascular Compounds for Treating Angina | ALOX5, PNPO, KCNMB1 | TSHR 3439/4885ALDH1A1 1179/4885THRB 1373/4885 |
| US-20020128553-A1 | Radiolabeled irreversible inhibitors of epidermal growth factor receptor tyrosine kinase and their use in radioimaging and radiotherapy | EGFR, ERBB2, TK1 | TSHR 126/4885ALDH1A1 3217/4885THRB 180/4885 |
| US-20040023936-A1 | 17 Beta-amino and hydroxylamino-11 beta-arylsteroids and their derivatives having agonist or antagonist hormonal properties | HSD17B11, HSD17B2, CYP17A1 | TSHR 269/4885ALDH1A1 1004/4885THRB 95/4885 |
| US-20070179140-A1 | Stereoisomerically Enriched 3-Aminocarbonyl Bicycloheptene Pyrimidinediamine Compounds And Their Uses | MKI67, PCNA, CCNI | TSHR 4647/4885ALDH1A1 705/4885THRB 2964/4885 |
| US-20070259936-A1 | Benzimidazole Modulators of VR1 | VRK1, VRK2, VIL1 | TSHR 3485/4885ALDH1A1 528/4885THRB 2659/4885 |
| US-20080009494-A1 | Cycloalkyl Substituted Pyrimidinediamine Compounds And Their Uses | MKI67, PCNA, TK1 | TSHR 3842/4885ALDH1A1 1807/4885THRB 3174/4885 |
| US-20040024010-A1 | 3-methylidenyl-2-indolinone modulators of protein kinase | DMPK, MAP4K3, MAP3K20 | TSHR 3160/4885ALDH1A1 2196/4885THRB 1001/4885 |
| US-20090226546-A1 | COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS | PNLIP, SLC5A1, SLC5A2 | TSHR 4807/4885ALDH1A1 1068/4885THRB 4269/4885 |
| US-20020010158-A1 | Cardioprotective phosphonates and malonates | PDXK, PHOSPHO1, PNPO | TSHR 3443/4885ALDH1A1 2080/4885THRB 3219/4885 |
| US-20110098477-A1 | Method Of Producing Compound Having Anti-Hcv Activity | ERG28, HCCS, BCAT2 | TSHR 4337/4885ALDH1A1 854/4885THRB 3900/4885 |
| US-20020146718-A1 | Peptide nucleic acids having 2,6-diaminopurine nucleobases | NT5C3B, NSUN2, PCNA | TSHR 2547/4885ALDH1A1 3141/4885THRB 3720/4885 |
| US-20030153570-A1 | Aryl triazines as LPAAT-SS inhibitors and uses thereof | LPCAT3, LPCAT1, PLAAT2 | TSHR 769/4885ALDH1A1 1286/4885THRB 1017/4885 |
| US-20060222886-A1 | Arylpyrene compounds | AXIN2, PNN, AHR | TSHR 4803/4885ALDH1A1 11/4885THRB 4773/4885 |
| US-20040121988-A1 | Treatment of cerebrovascular disease | PNPO, PLPBP, PDXK | TSHR 1925/4885ALDH1A1 1627/4885THRB 1881/4885 |
| US-20060035891-A1 | Cycloalkyl substituted pyrimidinediamine compounds and their uses | MKI67, PCNA, TK1 | TSHR 3842/4885ALDH1A1 1807/4885THRB 3174/4885 |
| US-20110301170-A1 | Inhibitors of JNK | MAPK6, MAP3K6, MAPK1 | TSHR 2258/4885ALDH1A1 4295/4885THRB 1507/4885 |
| US-20130210814-A1 | Cycloalkyl Substituted Pyrimidinediamine Compounds And Their Uses | MKI67, PCNA, TK1 | TSHR 3842/4885ALDH1A1 1807/4885THRB 3174/4885 |
| US-20230321130-A1 | Senolytic Compositions and Uses Thereof | SENP3, SENP6, SENP1 | TSHR 3671/4885ALDH1A1 1807/4885THRB 4037/4885 |
| US-20210246138-A1 | CDK8/19 INHIBITORS | CDK8, CDK9, CDK18 | TSHR 3967/4885ALDH1A1 3487/4885THRB 3252/4885 |
| US-20060167249-A1 | Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses | MKI67, PCNA, CCNI | TSHR 4647/4885ALDH1A1 705/4885THRB 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.