Levomepromazine

Levomepromazine

SCHEMBL218717

COc1ccc2c(c1)N(C[C@H](C)CN(C)C)c1ccccc1S2.O=C(O)/C=C\C(=O)O

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

DRD2DRD3DRD4

The experimentally established mechanism targets of Levomepromazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 known ✓ P35462 4/20 0.82
DRD2 known ✓ P14416 2/20 0.46
DRD4 known ✓ P21917 1/20 0.43
LMNA P02545 5/20 0.82
CHRM2 P08172 4/20 0.82
HTR1A P08908 4/20 0.82
CHRM1 P11229 4/20 0.82
ADRA1A P35348 4/20 0.82
OPRM1 P35372 4/20 0.82
KCNH2 Q12809 4/20 0.82
CYP2D6 P10635 4/20 0.82
ADRA2A P08913 3/20 0.82
DRD1 P21728 3/20 0.82
CYP3A4 P08684 3/20 0.82
MAPK1 P28482 3/20 0.82
TBXA2R P21731 2/20 0.82
CYP1A2 P05177 2/20 0.82
PTGS1 P23219 2/20 0.82
GFER P55789 1/20 0.62
SLC6A2 P23975 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Levomepromazine SCHEMBL29727144 1.00 LMNA (0.82) LMNACHRM2HTR1ACHRM1ADRA1A
Levomepromazine SCHEMBL29697036 1.00 LMNA (0.82) LMNACHRM2HTR1ACHRM1ADRA1A
Levomepromazine SCHEMBL27701483 0.93 LMNA (0.88) LMNACHRM2HTR1ACHRM1ADRA1A
Levomepromazine SCHEMBL29508092 0.91 CYP2D6 (1.00) LMNACHRM2HTR1ACHRM1ADRA1A
Levomepromazine SCHEMBL8762418 0.91 CYP2D6 (1.00) LMNACHRM2HTR1ACHRM1ADRA1A
Dextromepromazine SCHEMBL23859840 0.91 CYP2D6 (1.00) LMNACHRM2HTR1ACHRM1ADRA1A
Levomepromazine SCHEMBL6944555 0.91 CYP2D6 (1.00) LMNACHRM2HTR1ACHRM1ADRA1A
Levomepromazine SCHEMBL29425180 0.91 CYP2D6 (1.00) LMNACHRM2HTR1ACHRM1ADRA1A
Levomepromazine SCHEMBL25462 0.91 CYP2D6 (1.00) LMNACHRM2HTR1ACHRM1ADRA1A
Levomepromazine SCHEMBL29384983 0.91 CYP2D6 (1.00) LMNACHRM2HTR1ACHRM1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 469 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220050117-A1 GLX-DERIVED MOLECULE DETECTION GLX ANALYTIX APS (DK) 2022-02-17 US claimed
EP-2743263-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF LEVOMEPROMAZINE MALEATE ZCL CHEMICALS LTD (IN) 2018-01-03 EP claimed
US-9757376-B2 Pharmaceutical compositions GM PHARMACEUTICALS, INC. (US) 2017-09-12 US claimed
US-20170112829-A1 USE OF COMPOUNDS BINDING TO THE SIGMA RECEPTOR LIGANDS FOR THE TREATMENT OF NEUROPATHIC PAIN DEVELOPING AS A CONSEQUENCE OF CHEMOTHERAPY LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2017-04-27 US claimed
EP-2743263-A1 An improved process for the preparation of levomepromazine maleate ZCL Chemicals Ltd. (IN) 2014-06-18 EP claimed
US-20110224141-A1 METHODS AND RELATED COMPOSITIONS FOR THE TREATMENT OF CANCER STC.UNM (US) 2011-09-15 US claimed
US-20110052723-A1 USE OF COMPOUNDS BINDING TO THE SIGMA RECEPTOR LIGANDS FOR THE TREATMENT OF NEUROPATHIC PAIN DEVELOPING AS A CONSEQUENCE OF CHEMOTHERAPY LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2011-03-03 US claimed
WO-2010101649-A2 SIGMA 1 RECEPTOR INHIBITION AS A NOVEL THERAPEUTICAL APPROACH AGAINST HEPATITIS C VIRUS INFECTION GASTAMINZA PABLO (US) 2010-09-10 WO claimed
WO-2009148623-A2 METHODS AND RELATED COMPOSITIONS FOR THE TREATMENT OF CANCER STC.UNM (US) 2009-12-10 WO claimed
EP-2090311-A1 Use of compounds binding to the sigma receptor ligands for the treatment of neuropathic pain developing as a consequence of chemotherapy Laboratorios Del. Dr. Esteve, S.A. (ES) 2009-08-19 EP claimed
US-20090042898-A1 USE OF COMPOUNDS ACTIVE ON THE SIGMA RECEPTOR FOR THE TREATMENT OF MECANICAL ALLODYNIA LABORATORIOS DEL DR. ESTEVE S.A. (ES) 2009-02-12 US claimed
EP-1829534-A1 Use of compounds binding to the sigma receptor for the treatment of metabolic syndrome LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-09-05 EP claimed
CN-1988896-A Use of compounds active on the sigma receptor for the treatment of mechanical allodynia ESTEVE LABOR DR (ES) 2007-06-27 CN claimed
EP-1787679-A1 Use of compounds binding to the sigma receptor for the treatment of diabetes-associated pain LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-05-23 EP claimed
EP-1641446-A1 PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF Pediamed Pharmaceuticals, Inc. (US) 2006-04-05 EP claimed
WO-2004112771-A1 PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF PEDIAMED PHARMACEUTICALS, INC. (US) 2004-12-29 WO claimed
US-20040259809-A1 Pharmaceutical compositions including an antihistamine and a stimulant and method of use thereof PEDIAMED PHARMACEUTICALS, INC. 2004-12-23 US claimed
EP-0251904-B1 PROCESS FOR THE PREPARATION OF ACIDIC LEVOMEPROMAZINE MALEATE RHONE-POULENC SANTE (FR) 1990-01-10 EP claimed
US-4798895-A Process for preparing levomepromazine hydrogen maleate RHONE-POULENC SANTE (FR) 1989-01-17 US claimed
US-20250288541-A1 BINGE BEHAVIOR REGULATORS CLEARMIND LABS CORP. (CA) 2025-09-18 US disclosed
US-12384770-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-08-12 US disclosed
US-12357590-B2 Binge behavior regulators Clearmind Medicine Inc. (CA) 2025-07-15 US disclosed
US-12350242-B2 Binge behavior regulators Clearmind Medicine Inc. (CA) 2025-07-08 US disclosed
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES Didenko, Kirill (US) 2025-07-03 US disclosed
US-20250052770-A1 GLX-DERIVED MOLECULE DETECTION GLX ANALYTIX APS (DK) 2025-02-13 US disclosed
US-20250042870-A1 DP ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2025-02-06 US disclosed
US-12202829-B2 Heterocyclic compound FIMECS, INC. (JP) 2025-01-21 US disclosed
US-20240343721-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-10-17 US disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
US-12084436-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-09-10 US disclosed
US-12064402-B2 Binge behavior regulators Clearmind Medicine Inc. (CA) 2024-08-20 US disclosed
EP-3854781-B1 DP ANTAGONISTS ONO PHARMACEUTICAL CO (JP) 2024-05-22 EP disclosed
US-11958845-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-04-16 US disclosed
CN-112500301-B Regulator for longitudinal behavior 以西结·戈兰 2024-02-13 CN disclosed
US-20240016745-A1 TIMED-ELUTION MASKING PARTICLES AND ORAL PHARMACEUTICAL COMPOSITION CONTAINING THE SAME TOWA PHARMACEUTICAL CO., LTD. (JP) 2024-01-18 US disclosed
US-11851449-B2 Heterocyclic amide compounds having an RORvt inhibitory action TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-12-26 US disclosed
EP-3494229-B1 HIGH THROUGHPUT CELL-BASED SCREENING FOR APTAMERS MEIRAGTX UK II LTD (GB) 2023-10-25 EP disclosed
EP-4260847-A1 TIMED-ELUTION MASKING PARTICLES AND ORAL PHARMACEUTICAL COMPOSITION CONTAINING SAME TOWA PHARMACEUTICAL CO., LTD. (JP) 2023-10-18 EP disclosed
WO-2023187599-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES DIDENKO KIRILL (MX) 2023-10-05 WO disclosed
US-20230242529-A1 HETEROCYCLIC COMPOUND FIMECS, INC. (JP) 2023-08-03 US disclosed
US-20230183227-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-06-15 US disclosed
EP-3018123-B1 AMIDE COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2023-05-10 EP disclosed
US-11639354-B2 Heterocyclic compound FIMECS, INC. (JP) 2023-05-02 US disclosed
WO-2023037254-A1 METHODS AND COMPOUNDS FOR TREATING CORONAVIRIDAE VIRUS INFECTIONS DIDENKO KIRILL (MX) 2023-03-16 WO disclosed
US-20230065720-A1 High Throughput Cell-Based Screening for Aptamers MeiraGTx Gene Regulation Limited (GB) 2023-03-02 US disclosed
US-20230001128-A1 AEROSOLIZATION SYSTEMS, METHODS, AND APPARATUSES SHUSTER GARY STEPHEN (CA) 2023-01-05 US disclosed
US-11453661-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-09-27 US disclosed
EP-4034536-A1 2-ISOINDOL-1,3,4-OXADIAZOLE DERIVATIVES USEFUL AS HDAC6 INHIBITORS Takeda Pharmaceutical Company Limited (JP) 2022-08-03 EP disclosed
CN-114846012-A 2-isoindole-1, 3, 4-oxadiazole derivatives useful as HDAC6 inhibitors 武田药品工业株式会社 2022-08-02 CN disclosed
US-20220204468-A1 DP ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2022-06-30 US disclosed
US-11371077-B2 High throughput cell-based screening for aptamers MEIRAGTX UK II LIMITED (GB) 2022-06-28 US disclosed
WO-2022124243-A1 TIMED-ELUTION MASKING PARTICLES AND ORAL PHARMACEUTICAL COMPOSITION CONTAINING SAME 東和薬品株式会社 2022-06-16 WO disclosed
US-11319296-B2 DP antagonist ONO PHARMACEUTICAL CO., LTD. (JP) 2022-05-03 US disclosed
US-20220098180-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-03-31 US disclosed
US-20220050117-A1 GLX-DERIVED MOLECULE DETECTION GLX ANALYTIX APS (DK) 2022-02-17 US disclosed
US-20220033371-A1 DP ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2022-02-03 US disclosed
EP-3919055-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2021-12-08 EP disclosed
US-20210330609-A1 BINGE BEHAVIOR REGULATORS CLEARMIND LABS CORP. (CA) 2021-10-28 US disclosed
US-20210330607-A1 BINGE BEHAVIOR REGULATORS CLEARMIND LABS CORP. (CA) 2021-10-28 US disclosed
US-20210330608-A1 BINGE BEHAVIOR REGULATORS CLEARMIND LABS CORP. (CA) 2021-10-28 US disclosed
EP-3181616-B1 CELLULOSE MICROPOWDER ASAHI CHEMICAL IND (JP) 2021-09-15 EP disclosed
US-20210277030-A1 AMIDE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-09-09 US disclosed
US-11077072-B2 Binge behavior regulators Clearmind Medicine Inc. 2021-08-03 US disclosed
EP-3854781-A1 DP ANTAGONIST ONO Pharmaceutical Co., Ltd. (JP) 2021-07-28 EP disclosed
US-11053262-B2 Heterocyclic amide compounds having RORyT inhibitory action TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-07-06 US disclosed
US-20210179614-A1 HETEROCYCLIC COMPOUND FIMECS, INC. (JP) 2021-06-17 US disclosed
EP-3831811-A1 HETEROCYCLIC COMPOUND Fimecs, Inc. (JP) 2021-06-09 EP disclosed
CN-112739680-A DP antagonists 小野药品工业株式会社 2021-04-30 CN disclosed
US-10987365-B2 Compositions and methods for the treatment of pain GM PHARMACEUTICALS, INC. (US) 2021-04-27 US disclosed
WO-2021060567-A1 2-ISOINDOL-1,3,4-OXADIAZOLE DERIVATIVES USEFUL AS HDAC6 INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-04-01 WO disclosed
US-20210094944-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-04-01 US disclosed
CN-109923101-B Cyclic compound 武田药品工业株式会社 2021-03-09 CN disclosed
US-20210046044-A1 USE OF (+)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE TO TREAT ADDICTIVE AND ALCOHOL-RELATED DISORDERS MCKINNEY ANTHONY ALEXANDER (US) 2021-02-18 US disclosed
CN-108026088-B Oxadiazole derivatives as HDAC inhibitors 武田药品工业株式会社 2021-02-12 CN disclosed
EP-2486917-B1 COATING FILM, AND GRANULES AND TABLETS EACH UTILIZING SAME ASAHI CHEMICAL IND (JP) 2020-11-25 EP disclosed
US-20200339577-A1 1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-10-29 US disclosed
US-20200297700-A1 BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF TOBIRA THERAPEUTICS INC (US) 2020-09-24 US disclosed
EP-3705469-A1 BINGE BEHAVIOR REGULATORS GOLAN, Ezekiel (CA) 2020-09-09 EP disclosed
US-10745397-B2 1-Substituted 1,2,3,4-tetrahydro-1,7-naphthyridin-8-amine derivatives and their use as EP4 receptor antagonists TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-08-18 US disclosed
US-10738004-B2 Cyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-08-11 US disclosed
WO-2020158762-A1 HETEROCYCLIC COMPOUND 武田薬品工業株式会社 2020-08-06 WO disclosed
US-20200239940-A1 High Throughput Cell-Based Screening For Aptamers MEIRAGTX UK II LIMITED (GB) 2020-07-30 US disclosed
EP-3661931-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2020-06-10 EP disclosed
WO-2020059790-A1 DP ANTAGONIST 小野薬品工業株式会社 2020-03-26 WO disclosed
EP-3325475-B1 OXADIAZOLE DERIVATIVES USEFUL AS HDAC INHIBITORS TAKEDA PHARMACEUTICALS CO (JP) 2020-03-18 EP disclosed
EP-3230255-B1 BINGE BEHAVIOR REGULATORS GOLAN EZEKIEL (CA) 2020-03-18 EP disclosed
WO-2020027225-A1 HETEROCYCLIC COMPOUND ファイメクス株式会社 2020-02-06 WO disclosed
EP-3066094-B1 PYRAZOLE FOR THE TREATMENT AUTOIMMUNE DISORDERS TAKEDA PHARMACEUTICALS CO (JP) 2020-01-08 EP disclosed
EP-3325490-B1 1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICALS CO (JP) 2019-12-18 EP disclosed
US-10472376-B2 Amide compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-11-12 US disclosed
US-10435399-B2 HDAC6 inhibitory heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-10-08 US disclosed
CN-106795118-B Heterocyclic compound and their purposes as relevant orphan receptor (ROR) the GAMMA-T inhibitor of retinoids 武田药品工业株式会社 2019-10-08 CN disclosed
US-10406123-B2 Binge behavior regulators CLEARMIND LABS CORP. (CA) 2019-09-10 US disclosed
US-10406146-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-09-10 US disclosed
US-20190233370-A1 CYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-08-01 US disclosed
US-10357484-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-07-23 US disclosed
EP-3511320-A1 CYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2019-07-17 EP disclosed
CN-109923101-A Cyclic compound 武田药品工业株式会社 2019-06-21 CN disclosed
EP-3494229-A2 HIGH THROUGHPUT CELL-BASED SCREENING FOR APTAMERS Meiragtx UK II Limited (GB) 2019-06-12 EP disclosed
US-10308643-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-06-04 US disclosed
US-20190135799-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-05-09 US disclosed
EP-2184056-B1 PROCESS FOR PRODUCTION OF TABLETS CONTAINING BOTH CRYSTALLINE CELLULOSE AND GRANULES ASAHI CHEMICAL IND (JP) 2019-04-24 EP disclosed
US-20190054042-A1 BINGE BEHAVIOR REGULATORS CLEARMIND LABS CORP. (CA) 2019-02-21 US disclosed
US-20190038604-A1 BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF TOBIRA THERAPEUTICS, INC. (US) 2019-02-07 US disclosed
WO-2019027054-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-02-07 WO disclosed
US-20190008836-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-01-10 US disclosed
US-10137096-B2 Binge behavior regulators CLEARMIND LABS CORP. (CA) 2018-11-27 US disclosed
US-20180319812-A1 HETEROCYCLIC COMPOUND ACTION MEDICAL TECHNOLOGIES, LLC 2018-11-08 US disclosed
US-20180296527-A1 USE OF (+)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE TO TREAT ADDICTIVE AND ALCOHOL-RELATED DISORDERS ETHISMOS RESEARCH, INC. 2018-10-18 US disclosed
US-10093629-B2 Heterocyclic compounds and their use as retinoid-related orphan receptor (ROR) gamma-T inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-10-09 US disclosed
US-10081624-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-09-25 US disclosed
US-20180263967-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-09-20 US disclosed
CN-105899505-B Pyrazoles for the treatment of autoimmune disorders 武田药品工业株式会社 2018-08-28 CN disclosed
US-10053468-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-08-21 US disclosed
US-20180222896-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-08-09 US disclosed
CN-108368127-A 1,2,3,4- tetrahydrochysene -1,7- naphthyridines -8- the amine derivatives of 1- substitutions and its purposes as EP4 receptor antagonists 武田药品工业株式会社 2018-08-03 CN disclosed
US-20180215754-A1 1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-08-02 US disclosed
US-10016367-B2 Cellulose micropowder ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-07-10 US disclosed
EP-3342772-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2018-07-04 EP disclosed
US-10000488-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-06-19 US disclosed
EP-3325475-A1 OXADIAZOLE DERIVATIVES USEFUL AS HDAC INHIBITORS Takeda Pharmaceutical Company Limited (JP) 2018-05-30 EP disclosed
EP-3327019-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2018-05-30 EP disclosed
EP-3325490-A1 1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS Takeda Pharmaceutical Company Limited (JP) 2018-05-30 EP disclosed
CN-108026088-A Oxadiazole derivatives as HDAC inhibitors 武田药品工业株式会社 2018-05-11 CN disclosed
US-20180118708-A1 CYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-05-03 US disclosed
WO-2018070874-A1 MEANS AND METHODS FOR REDUCING OR AVOIDING ANTIBIOTIC RESISTANCE AND SPREAD OF VIRULENCE IN HUMAN PATHOGENS RIJKSUNIVERSITEIT GRONINGEN (NL) 2018-04-19 WO disclosed
US-20180099000-A1 Method for the Prophylaxis or Treatment of Systemic Lupus Erythematosus and/or Lupus Nephritis MILLENNIUM PHARM INC (US) 2018-04-12 US disclosed
US-20180085326-A1 BINGE BEHAVIOR REGULATORS CLEARMIND LABS CORP. (CA) 2018-03-29 US disclosed
CN-107835800-A cyclic compound 武田药品工业株式会社 2018-03-23 CN disclosed
EP-3296296-A1 CYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2018-03-21 EP disclosed
EP-3294706-A1 CYCLIC COMPOUNDS Takeda Pharmaceutical Company Limited (JP) 2018-03-21 EP disclosed
WO-2018030550-A1 HETEROCYCLIC COMPOUNDS WITH AN ROR(GAMMA)T MODULATING ACTIVITY TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-02-15 WO disclosed
US-9890145-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-02-13 US disclosed
WO-2018025085-A2 HIGH THROUGHPUT CELL-BASED SCREENING FOR APTAMERS MEIRAGTX UK II LIMITED (GB) 2018-02-08 WO disclosed
CN-105263932-B Heterocyclic compound 武田药品工业株式会社 2018-01-09 CN disclosed
EP-2743263-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF LEVOMEPROMAZINE MALEATE ZCL CHEMICALS LTD (IN) 2018-01-03 EP disclosed
EP-2743263-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF LEVOMEPROMAZINE MALEATE ZCL CHEMICALS LTD (IN) 2018-01-03 EP disclosed
EP-2980089-B1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2017-12-20 EP disclosed
US-9834520-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-12-05 US disclosed
US-9828357-B2 Cyclic compounds TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-11-28 US disclosed
CN-107406369-A Relaxant behavior modulators 以西结·戈兰 2017-11-28 CN disclosed
EP-3230255-A1 BINGE BEHAVIOR REGULATORS Golan, Ezekiel (CA) 2017-10-18 EP disclosed
US-20170258728-A1 CELLULOSE MICROPOWDER ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-09-14 US disclosed
US-9757376-B2 Pharmaceutical compositions GM PHARMACEUTICALS, INC. (US) 2017-09-12 US disclosed
US-20170253591-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-09-07 US disclosed
EP-2738170-B1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2017-08-30 EP disclosed
US-9744134-B2 Orally disintegrating tablet containing bitterness-masking granules ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-08-29 US disclosed
EP-2810659-B1 ORALLY DISINTEGRATING TABLET CONTAINING BITTERNESS-MASKING GRANULES ASAHI CHEMICAL IND (JP) 2017-08-09 EP disclosed
US-20170216251-A1 USE OF (+)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE TO TREAT ADDICTIVE AND ALCOHOL-RELATED DISORDERS ETHISMOS RESEARCH, INC. 2017-08-03 US disclosed
EP-2759533-B1 CONDENSED HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2017-08-02 EP disclosed
EP-3192791-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2017-07-19 EP disclosed
EP-3187497-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2017-07-05 EP disclosed
US-20170174682-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-06-22 US disclosed
EP-3181616-A1 CELLULOSE MICROPOWDER ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-06-21 EP disclosed
CN-106795118-A Heterocyclic compound to they as related orphan receptor (ROR) the GAMMA T inhibitor of retinoids purposes 武田药品工业株式会社 2017-05-31 CN disclosed
US-20170144973-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE AS RETINOID-RELATED ORPHAN RECEPTOR (ROR) GAMMA-T INHIBITORS Takenda Pharmaceutical Company Limited (JP) 2017-05-25 US disclosed
US-9650343-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-05-16 US disclosed
EP-3164388-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE AS RETINOID-RELATED ORPHAN RECEPTOR (ROR) GAMMA-T INHIBITORS Takeda Pharmaceutical Company Limited (JP) 2017-05-10 EP disclosed
US-9643967-B2 Pyrrolo[3,2-c]pyridine derivatives as TLR inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-05-09 US disclosed
US-9637483-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-05-02 US disclosed
US-20170112829-A1 USE OF COMPOUNDS BINDING TO THE SIGMA RECEPTOR LIGANDS FOR THE TREATMENT OF NEUROPATHIC PAIN DEVELOPING AS A CONSEQUENCE OF CHEMOTHERAPY LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2017-04-27 US disclosed
US-9630924-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-04-25 US disclosed
US-20170107240-A1 AMIDE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-04-20 US disclosed
US-20170105969-A1 CENICRIVIROC FOR THE TREATMENT OF HIV-2 INFECTION TOBIRA THERAPEUTICS, INC. 2017-04-20 US disclosed
US-20170096422-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-04-06 US disclosed
EP-3148538-A1 CENICRIVIROC FOR THE TREATMENT OF HIV-2 INFECTION Tobira Therapeutics, Inc. (US) 2017-04-05 EP disclosed
US-9611244-B2 Cyclic compounds TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-04-04 US disclosed
US-20170066737-A1 CYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-03-09 US disclosed
WO-2017038909-A1 HETEROCYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-03-09 WO disclosed
US-20170050974-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-02-23 US disclosed
US-20170049737-A1 (2R)-2-PROPYLOCTANOIC ACID FOR FUNCTIONAL BRAIN DISEASE ONO PHARMACEUTICAL CO., LTD. (JP) 2017-02-23 US disclosed
CN-106459040-A Heterocyclic compound 武田药品工业株式会社 2017-02-22 CN disclosed
US-9573903-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-02-21 US disclosed
EP-3124487-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2017-02-01 EP disclosed
WO-2017014321-A1 OXADIAZOLE DERIVATIVES USEFUL AS HDAC INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-01-26 WO disclosed
US-20170020873-A1 PHARMACEUTICAL COMPOSITIONS GM PHARMACEUTICALS, INC. 2017-01-26 US disclosed
WO-2017014323-A1 1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-01-26 WO disclosed
CN-104507940-B Heterocyclic compounds 武田药品工业株式会社 2017-01-25 CN disclosed
CN-104271574-B Heterocyclic compounds 武田药品工业株式会社 2017-01-25 CN disclosed
US-20170015655-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-01-19 US disclosed
US-20170008885-A1 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AS TLR INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-01-12 US disclosed
US-9533966-B2 Cyclic compounds TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-01-03 US disclosed
WO-2016199943-A1 HETEROCYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-12-15 WO disclosed
US-20160361356-A1 METHODS, COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR ENHANCING SURVIVABILITY OF CELLS, TISSUES, ORGANS, AND ORGANISMS FRED HUTCHINSON CANCER RESEARCH CENTER 2016-12-15 US disclosed
US-9517221-B2 (2R)-2-propyloctanoic acid for functional brain disease ONO PHARMACEUTICAL CO., LTD. (JP) 2016-12-13 US disclosed
WO-2016182036-A1 CYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-11-17 WO disclosed
US-20160326133-A1 CYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-11-10 US disclosed
US-20160326102-A1 CYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-11-10 US disclosed
US-20160311811-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-10-27 US disclosed
EP-2050438-B1 SPHERICAL CRUDE GRANULE AND METHOD FOR PRODUCTION THEREOF ASAHI CHEMICAL IND (JP) 2016-10-19 EP disclosed
EP-3080124-A1 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AS TLR INHIBITORS Takeda Pharmaceutical Company Limited (JP) 2016-10-19 EP disclosed
US-9463191-B2 Pharmaceutical compositions GM PHARMACEUTICALS, INC. (US) 2016-10-11 US disclosed
EP-3066094-A1 PYRAZOLE FOR THE TREATMENT AUTOIMMUNE DISORDERS Takeda Pharmaceutical Company Limited (JP) 2016-09-14 EP disclosed
US-9439865-B2 Coating film, and granules and tablets each utilizing same ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-09-13 US disclosed
US-20160250238-A1 Method for the Prophylaxis or Treatment of Systemic Lupus Erythematosus and/or Lupus Nephritis MILLENNIUM PHARMACEUTICALS, INC. (US) 2016-09-01 US disclosed
US-20160251352-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2016-09-01 US disclosed
US-20160229814-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-08-11 US disclosed
EP-3052105-A1 METHOD FOR THE PROPHYLAXIS OR TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS AND/OR LUPUS NEPHRITIS Millennium Pharmaceuticals, Inc. (US) 2016-08-10 EP disclosed
WO-2016123541-A2 CENICRIVIROC FOR THE TREATMENT OF ENCEPHALITIS INFECTION TOBIRA THERAPEUTICS, INC. (US) 2016-08-04 WO disclosed
US-20160176822-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL (JP) 2016-06-23 US disclosed
US-20160176873-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL (JP) 2016-06-23 US disclosed
US-20160176872-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL (JP) 2016-06-23 US disclosed
US-9371320-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-06-21 US disclosed
WO-2016092546-A1 BINGE BEHAVIOR REGULATORS GOLAN EZEKIEL (IL) 2016-06-16 WO disclosed
US-9365520-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-06-14 US disclosed
WO-2016088903-A1 HETEROCYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-06-09 WO disclosed
US-20160159773-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-06-09 US disclosed
EP-3029031-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2016-06-08 EP disclosed
EP-3018123-A1 AMIDE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2016-05-11 EP disclosed
EP-3018126-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2016-05-11 EP disclosed
US-9326974-B2 Methods and related compositions for the treatment of cancer STC.UNM (US) 2016-05-03 US disclosed
US-9321757-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-04-26 US disclosed
EP-2994129-A1 USE OF (+)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE TO TREAT ADDICTIVE AND ALCOHOL-RELATED DISORDERS Euthymic Bioscience, Inc. (US) 2016-03-16 EP disclosed
US-20160039811-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-02-11 US disclosed
WO-2016021742-A1 HETEROCYCLIC COMPOUNDS AS EP4 RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-02-11 WO disclosed
EP-2980089-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2016-02-03 EP disclosed
EP-2975031-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2016-01-20 EP disclosed
US-20160008326-A1 BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-01-14 US disclosed
US-20160002169-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-01-07 US disclosed
WO-2016002968-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE AS RETINOID-RELATED ORPHAN RECEPTOR (ROR) GAMMA-T INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-01-07 WO disclosed
WO-2015187663-A1 CENICRIVIROC FOR THE TREATMENT OF HIV-2 INFECTION TOBIRA THERAPEUTICS, INC. (US) 2015-12-10 WO disclosed
EP-2949212-A1 USE OF OXYGEN ANTAGONISTS FOR EX VIVO PRESERVATION OF TISSUES OR ORGANS Fred Hutchinson Cancer Research Center (US) 2015-12-02 EP disclosed
US-9187453-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-11-17 US disclosed
US-9156837-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-10-13 US disclosed
US-20150265615-A1 PHARMACEUTICAL COMPOSITIONS GM PHARMACEUTICALS, INC. 2015-09-24 US disclosed
US-9120776-B2 Condensed heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-09-01 US disclosed
US-9085578-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-07-21 US disclosed
WO-2015088045-A1 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AS TLR INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-06-18 WO disclosed
US-20150164064-A1 METHODS, COMPOSITIONS AND DEVICES FOR INDUCING STASIS IN CELLS, TISSUES, ORGANS, AND ORGANISMS FRED HUTCHINSON CANCER RESEARCH CENTER 2015-06-18 US disclosed
US-9050289-B2 Pharmaceutical compositions GM PHARMACEUTICALS, INC. (US) 2015-06-09 US disclosed
US-20150141406-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-05-21 US disclosed
US-20150133451-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-05-14 US disclosed
WO-2015068856-A1 PYRAZOLE FOR THE TREATMENT AUTOIMMUNE DISORDERS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-05-14 WO disclosed
US-20150104513-A1 COATING FILM, AND GRANULES AND TABLETS EACH UTILIZING SAME ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-04-16 US disclosed
WO-2015051067-A1 METHOD FOR THE PROPHYLAXIS OR TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS AND/OR LUPUS NEPHRITIS MILLENNIUM PHARMACEUTICALS, INC. (US) 2015-04-09 WO disclosed
EP-2857400-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2015-04-08 EP disclosed
CN-104507940-A Heterocyclic compounds TAKEDA PHARMACEUTICAL 2015-04-08 CN disclosed
US-20150094296-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-04-02 US disclosed
US-8992988-B2 Coating film, and granules and tablets each utilizing same ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-03-31 US disclosed
US-20150044286-A1 ORALLY DISINTEGRATING TABLET CONTAINING BITTERNESS-MASKING GRANULES ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-02-12 US disclosed
US-20150045349-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED 2015-02-12 US disclosed
EP-2832734-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2015-02-04 EP disclosed
EP-2298352-B1 PERCUTANEOUS ABSORPTION ENHANCER AND TRANSDERMAL PREPARATION USING THE SAME TOA EIYO LTD (JP) 2015-01-14 EP disclosed
EP-2818473-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2014-12-31 EP disclosed
EP-2161036-B1 CELLULOSE FINE CORE PARTICLE, AND METHOD FOR PRODUCTION THEREOF ASAHI KASEI CHEMICALS CORP (JP) 2014-12-10 EP disclosed
EP-2810659-A1 ORALLY DISINTEGRATING TABLET CONTAINING BITTERNESS-MASKING GRANULES Asahi Kasei Chemicals Corporation (JP) 2014-12-10 EP disclosed
US-20140343347-A1 METHODS AND RELATED COMPOSITIONS FOR THE TREATMENT OF CANCER THE REGENTS OF THE UNIVERSITY OF NEW MEXICO 2014-11-20 US disclosed
US-20140315892-A1 USE OF (+)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE TO TREAT ADDICTIVE AND ALCOHOL-RELATED DISORDERS ETHISMOS RESEARCH, INC. 2014-10-23 US disclosed
US-8835506-B2 Methods and related compositions for the treatment of cancer STC.UNM (US) 2014-09-16 US disclosed
US-8822535-B2 Methods, compositions and articles of manufacture for enhancing survivability of cells, tissues, organs, and organisms FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2014-09-02 US disclosed
US-20140228409-A1 CONDENSED HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-08-14 US disclosed
EP-2759533-A1 CONDENSED HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2014-07-30 EP disclosed
US-8771724-B2 Percutaneous absorption enhancer and transdermal preparation using the same TOA EIYO LTD. (JP) 2014-07-08 US disclosed
US-8765187-B2 Aqueous composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-07-01 US disclosed
EP-1981487-B1 LATEX OR PSEUDOLATEX COMPOSITIONS COATINGS AND COATING PROCESSES FMC CORP (US) 2014-06-25 EP disclosed
EP-2743263-A1 An improved process for the preparation of levomepromazine maleate ZCL Chemicals Ltd. (IN) 2014-06-18 EP disclosed
EP-2743263-A1 An improved process for the preparation of levomepromazine maleate ZCL Chemicals Ltd. (IN) 2014-06-18 EP disclosed
EP-2743263-A1 An improved process for the preparation of levomepromazine maleate ZCL Chemicals Ltd. (IN) 2014-06-18 EP disclosed
US-20140163001-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-06-12 US disclosed
EP-2738170-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2014-06-04 EP disclosed
US-8741943-B2 Bicyclic compound, production and use thereof TOBIRA THERAPEUTICS, INC. (US) 2014-06-03 US disclosed
US-8734830-B2 Manufacturing method and apparatus of ultrafine particles having uniform particle size distribution KOREA UNITED PHARM. INC. (KR) 2014-05-27 US disclosed
CN-1901795-B Methods, compositions and devices for inducing stasis in cells, tissues, organs, and organisms HUTCHINSON FRED CANCER RES 2014-03-26 CN disclosed
EP-2700401-A1 METHOD FOR PRODUCING ADHESIVE PATCH, AND ADHESIVE PATCH Hisamitsu Pharmaceutical Co., Inc. (JP) 2014-02-26 EP disclosed
US-20140037710-A1 METHOD FOR PRODUCING PATCH, AND PATCH HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2014-02-06 US disclosed
EP-1889839-B1 Bicyclic compound, production and use as HIV inhibitors TOBIRA THERAPEUTICS INC (US) 2013-11-06 EP disclosed
EP-1879599-B1 METHODS, COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR ENHANCING SURVIVABILITY OF CELLS, TISSUES, ORGANS, AND ORGANISMS HUTCHINSON FRED CANCER RES (US) 2013-10-16 EP disclosed
EP-1997902-B1 SCREENING METHOD UNIV HIROSHIMA (JP) 2013-09-18 EP disclosed
US-20130210835-A1 PHARMACEUTICAL COMPOSITIONS GM PHARMACEUTICAL, INC (US) 2013-08-15 US disclosed
US-20130123238-A1 Use of (+)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane to treat addictive and alcohol-related disorders ETHISMOS RESEARCH, INC. 2013-05-16 US disclosed
EP-2556830-A1 Combined effects of topiramate, ondansetron and naltrexone on alcohol consumption UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2013-02-13 EP disclosed
US-8367115-B2 Process for production of crystalline cellulose and tablets containing granules ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-02-05 US disclosed
US-8362058-B2 Bicyclic compound, production and use thereof TOBIRA THERAPEUTICS, INC. (US) 2013-01-29 US disclosed
US-8329420-B2 Screening method for a substance that binds to an intracellular region of TLR4 HIROSHIMA UNIVERSITY (JP) 2012-12-11 US disclosed
US-20120302592-A1 TOPIRAMATE PLUS NALTREXONE FOR THE TREATMENT OF ADDICTIVE DISORDERS UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2012-11-29 US disclosed
US-8309222-B2 Coated filaments COVIDIEN LP (US) 2012-11-13 US disclosed
US-20120282353-A1 METHODS, COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR HIF MODULATING COMPOUNDS FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2012-11-08 US disclosed
US-20120282255-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF ALCOHOLISM AND ALCOHOL DEPENDENCE SUMMIT BIOSCIENCES, INC. 2012-11-08 US disclosed
US-8298585-B2 Cellulose-based fine core particle and process for producing the same ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-10-30 US disclosed
US-20120232028-A1 Bicyclic Compound, Production and Use Thereof TOBIRA THERAPEUTICS, INC. (US) 2012-09-13 US disclosed
EP-2486917-A1 COATING FILM, AND GRANULES AND TABLETS EACH UTILIZING SAME Asahi Kasei Chemicals Corporation (JP) 2012-08-15 EP disclosed
US-20120189696-A1 COATING FILM, AND GRANULES AND TABLETS EACH UTILIZING SAME ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-07-26 US disclosed
US-8183273-B2 8-[4-(2-butoxyethoxy)phenyl]-1-isobutyl-N-[4-[[N-methyl-N-(tetrahydropyran-4-yl)amino]methyl]phenyl]-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide; HIV infectious diseases, chronic rheumatoid arthritis, autoimmune disease, allergic diseases, ischemic brain cell disease TOBIRA THERAPEUTICS, INC. (US) 2012-05-22 US disclosed
EP-1997486-B1 THERAPEUTIC AGENT FOR FUNCTIONAL BRAIN DISEASE ONO PHARMACEUTICAL CO (JP) 2012-05-16 EP disclosed
US-20120077856-A1 PHARMACEUTICAL PRODUCT TAKEDA PHARMACEUTICAL COMPANY LIMITED 2012-03-29 US disclosed
US-20120052479-A1 METHODS, COMPOSITIONS AND DEVICES FOR INDUCING STASIS IN TISSUES AND ORGANS ROTH MARK B (US) 2012-03-01 US disclosed
US-8088414-B2 Latex or pseudolatex compositions, coatings and coating processes FMC CORPORATION (US) 2012-01-03 US disclosed
EP-2206702-B1 Bicyclic compound, production and use thereof TOBIRA THERAPEUTICS INC (US) 2011-12-28 EP disclosed
EP-2366389-A1 Severe sepsis preventive therapeutic agent Takeda Pharmaceutical Company Limited (JP) 2011-09-21 EP disclosed
US-20110224141-A1 METHODS AND RELATED COMPOSITIONS FOR THE TREATMENT OF CANCER STC.UNM (US) 2011-09-15 US disclosed
EP-2363022-A2 Use of oxygen antagonists for the therapeutic treatment of mammals Fred Hutchinson Cancer Research Center (US) 2011-09-07 EP disclosed
US-20110200678-A1 MANUFACTURING METHOD AND APPARATUS OF ULTRAFINE PARTICLES HAVING UNIFORM PARTICLE SIZE DISTRIBUTION THE INDUSTRY METHOD AND APPARATUS OF ULTRAFINE PARTICLES HAVING UNIFORM PARTICLE SIZE DISTRIBUTIO (KR) 2011-08-18 US disclosed
US-7993681-B2 Exposing isolated tissue to an oxygen antagonist, e.g., a chalcogenide reducing agent, hydrogen sulfide; controlling cellular metabolism by binding to cytochrome oxidase and inhibiting or reducing oxidative phosphorylation activity; nontoxic; preservation; tranplantations; transfusions; transportation FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2011-08-09 US disclosed
US-20110184034-A1 Severe sepsis preventive therapeutic agent TAKEDA PHARMACEUTICAL COMPANY LIMITED 2011-07-28 US disclosed
US-7960416-B2 Oil-in-water emulsion of a 1-carboxylate-6-arylsulfamoyl cyclohexene and synthetic and naturally occurring phospholipids; nitric oxide or cytokine prodution inhibitors; cardiovascular disorders, autoimmune dieseases, septic shock; improved stability during autoclave sterilization TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-20110104241-A1 PERCUTANEOUS ABSORPTION ENHANCER AND TRANSDERMAL PREPARATION USING THE SAME TOA EIYO LTD. (JP) 2011-05-05 US disclosed
EP-2298352-A1 PERCUTANEOUS ABSORPTION ENHANCER AND TRANSDERMAL PREPARATION USING THE SAME TOA Eiyo Ltd. (JP) 2011-03-23 EP disclosed
US-20110065628-A1 Medication Combinations for the Treatment of Alcoholism and Drug Addiction UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2011-03-17 US disclosed
US-20110052723-A1 USE OF COMPOUNDS BINDING TO THE SIGMA RECEPTOR LIGANDS FOR THE TREATMENT OF NEUROPATHIC PAIN DEVELOPING AS A CONSEQUENCE OF CHEMOTHERAPY LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2011-03-03 US disclosed
EP-2260869-A2 Pharmaceutical product Takeda Pharmaceutical Company Limited (JP) 2010-12-15 EP disclosed
EP-2255785-A2 Stable emulsion composition Takeda Pharmaceutical Company Limited (JP) 2010-12-01 EP disclosed
WO-2010101649-A2 SIGMA 1 RECEPTOR INHIBITION AS A NOVEL THERAPEUTICAL APPROACH AGAINST HEPATITIS C VIRUS INFECTION GASTAMINZA PABLO (US) 2010-09-10 WO disclosed
US-20100216871-A1 USE OF COMPOUNDS HAVING CCR ANTAGONISM TSUCHIMORI NOBORU 2010-08-26 US disclosed
US-20100209504-A1 PROCESS FOR PRODUCTION OF CRYSTALLINE CELLULOSE AND TABLETS CONTAINING GRANULES ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-08-19 US disclosed
US-20100178332-A1 CELLULOSE-BASED FINE CORE PARTICLE AND PROCESS FOR PRODUCING THE SAME ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-07-15 US disclosed
EP-2206702-A1 Bicyclic compound, production and use thereof Tobira Therapeutics, Inc. (US) 2010-07-14 EP disclosed
US-20100172978-A1 AQUEOUS COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-07-08 US disclosed
EP-2184056-A1 PROCESS FOR PRODUCTION OF TABLETS CONTAINING BOTH CRYSTALLINE CELLULOSE AND GRANULES Asahi Kasei Chemicals Corporation (JP) 2010-05-12 EP disclosed
US-20100076006-A1 Topiramate Plus Naltrexone for the Treatment of Addictive Disorders UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2010-03-25 US disclosed
EP-2161036-A1 CELLULOSE FINE CORE PARTICLE, AND METHOD FOR PRODUCTION THEREOF Asahi Kasei Chemicals Corporation (JP) 2010-03-10 EP disclosed
EP-1423376-B1 BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF TOBIRA THERAPEUTICS INC (US) 2010-03-10 EP disclosed
US-20100041689-A1 Combined Effects of Topiramate and Ondansetron on Alcohol Consumption UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2010-02-18 US disclosed
US-20100016381-A1 STABLE EMULSION COMPOSITION TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-01-21 US disclosed
US-20090325999-A1 PERSONALIZED PHARMACEUTICAL KITS, PACKAGING AND COMPOSITIONS FOR THE TREATMENT OF ALLERGIC CONDITIONS JDP THERAPEUTICS, INC. 2009-12-31 US disclosed
US-20090317833-A1 Screening Method HIROSHIMA UNIVERSITY (JP) 2009-12-24 US disclosed
WO-2009148623-A2 METHODS AND RELATED COMPOSITIONS FOR THE TREATMENT OF CANCER STC.UNM (US) 2009-12-10 WO disclosed
EP-2124909-A2 COMBINED EFFECTS OF TOPIRAMATE AND ONDANSETRON ON ALCOHOL CONSUMPTION University Of Virginia Patent Foundation (US) 2009-12-02 EP disclosed
US-20090209585-A1 CYCLOALKENE DERIVATIVES, PROCESS FOR PRODUCTION OF THE DERIVATIVES, AND USE OF THE SAME TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-08-20 US disclosed
EP-2090311-A1 Use of compounds binding to the sigma receptor ligands for the treatment of neuropathic pain developing as a consequence of chemotherapy Laboratorios Del. Dr. Esteve, S.A. (ES) 2009-08-19 EP disclosed
US-20090196934-A1 SPHERICAL ELEMENTARY GRANULE AND METHOD FOR PRODUCTION THEREOF ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-08-06 US disclosed
EP-2085077-A1 Coating compositions for controlled relaease formulations SÜDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHSENFURT (DE) 2009-08-05 EP disclosed
US-20090181976-A1 Use of Compounds Binding to the Sigma Receptor for the Treatment of Metabolic Syndrome LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2009-07-16 US disclosed
US-7541478-B2 Coumarin derivative and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-06-02 US disclosed
US-20090105314-A1 Pharmaceutical Agent TAKEDA PHARMACEUTICAL COMPANY LIMITED 2009-04-23 US disclosed
EP-2050438-A1 SPHERICAL CRUDE GRANULE AND METHOD FOR PRODUCTION THEREOF Asahi Kasei Chemicals Corporation (JP) 2009-04-22 EP disclosed
WO-2008040002-A9 METHODS, COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR HIF MODULATING COMPOUNDS HUTCHINSON FRED CANCER RES (US) 2009-04-16 WO disclosed
EP-2039681-A1 CYCLOALKENE DERIVATIVES, PROCESS FOR PRODUCTION OF THE DERIVATIVES, AND USE OF THE SAME Takeda Pharmaceutical Company Limited (JP) 2009-03-25 EP disclosed
US-20090062355-A1 Pharmaceutical Product TAKEDA PHARMACEUTICAL COMPANY LIMITED 2009-03-05 US disclosed
WO-2009029308-A1 MEDICATION COMBINATIONS FOR THE TREATMENT OF ALCOHOLISM AND DRUG ADDICTION UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2009-03-05 WO disclosed
US-7495018-B2 Substituted 1,3-thiazole compounds, their production and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-02-24 US disclosed
US-20090042898-A1 USE OF COMPOUNDS ACTIVE ON THE SIGMA RECEPTOR FOR THE TREATMENT OF MECANICAL ALLODYNIA LABORATORIOS DEL DR. ESTEVE S.A. (ES) 2009-02-12 US disclosed
US-20090036529-A1 THERAPEUTIC AGENT FOR FUNCTIONAL BRAIN DISEASE ONO PHARMACEUTICAL CO., LTD. (JP) 2009-02-05 US disclosed
US-20090030032-A1 Bicyclic Compound, Production and Use Thereof TAKEDA CHEMICAL INDUSTRIES LTD. (JP) 2009-01-29 US disclosed
EP-2018855-A1 PHARMACEUTICAL AGENT Takeda Pharmaceutical Company Limited (JP) 2009-01-28 EP disclosed
EP-2018872-A1 PHARMACEUTICAL PRODUCT Takeda Pharmaceutical Company Limited (JP) 2009-01-28 EP disclosed
US-20090011051-A1 Methods, Compositions and Articles of Manufacture for HIF Modulating Compounds FRED HUTCHINSON CANCER RESEARCH CENTER 2009-01-08 US disclosed
EP-2008672-A1 Coated filaments Tyco Healthcare Group, LP (US) 2008-12-31 EP disclosed
EP-1997486-A1 THERAPEUTIC AGENT FOR FUNCTIONAL BRAIN DISEASE ONO PHARMACEUTICAL CO., LTD. (JP) 2008-12-03 EP disclosed
EP-1997902-A1 SCREENING METHOD Hiroshima University (JP) 2008-12-03 EP disclosed
US-20080268243-A1 Coated filaments COVIDIEN LP 2008-10-30 US disclosed
EP-1981487-A1 LATEX OR PSEUDOLATEX COMPOSITIONS COATINGS AND COATING PROCESSES FMC CORPORATION (US) 2008-10-22 EP disclosed
US-20080226750-A1 Methods, Compositions and Articles of Manufacture for Treating Shock and Other Adverse Conditions FRED HUTCHINSON CANCER RESEARCH CENTER 2008-09-18 US disclosed
WO-2008095086-A2 TOPIRAMATE PLUS NALTREXONE FOR THE TREATMENT OF ADDICTIVE DISORDERS UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2008-08-07 WO disclosed
US-20080171726-A1 oxygen antagonists; reducing agent, preservatives; enhancing survivability and achieving stasis or pre-stasis in biological materials (cells, tissues); organ transplantation, hyperthermia, wound healing, hemorrhagic shock, cardioplegia for bypass surgery, neurodegeneration, hypothermia, and cancer ROTH MARK B 2008-07-17 US disclosed
US-20080171725-A1 Oxygen antagonists; reducing agent, preservatives; enhancing survivability and achieving stasis or pre-stasis in cells or tissues; organ transplantation, hyperthermia, wound healing, hemorrhagic shock, cardioplegia for bypass surgery, neurodegeneration, hypothermia, and cancer ROTH MARK B 2008-07-17 US disclosed
US-20080171093-A1 Methods, Compositions and Devices for Inducing Stasis in Cells, Tissues, Organs, and Organisms FRED HUTCHINSON CANCER RESEARCH CENTER, INC. (US) 2008-07-17 US disclosed
US-20080167314-A1 Condensed Imidazole Compound And Use Thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-07-10 US disclosed
US-20080161287-A1 Bicyclic compound, production and use thereof TAKEDA PHARMACEUTICAL COMPANY, LTD (JP) 2008-07-03 US disclosed
WO-2008077092-A2 COMBINED EFFECTS OF TOPIRAMATE AND ONDANSETRON ON ALCOHOL CONSUMPTION UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2008-06-26 WO disclosed
WO-2008070741-A1 COMPOSITIONS AND METHODS FOR ENHANCING SURVIVAL AND REDUCING INJURY UNDER ISCHEMIC OR HYPOXIC CONDITIONS IKARIA, INC. (US) 2008-06-12 WO disclosed
US-7371772-B2 Bicyclic compound, production and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-05-13 US disclosed
US-20080096924-A1 Amorphous Composition ONO PHARMACEUTICAL CO., LTD. (JP) 2008-04-24 US disclosed
US-20080085329-A1 Methods, Compositions and Devices for Inducing Stasis in Cells, Tissues, Organs, and Organisms FRED HUTCHINSON CANCER RESEARCH CENTER, INC. (US) 2008-04-10 US disclosed
WO-2008040002-A2 METHODS, COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR HIF MODULATING COMPOUNDS FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2008-04-03 WO disclosed
EP-1889839-A1 Bicyclic compound, production and use as HIV inhibitors Takeda Pharmaceutical Company Limited (JP) 2008-02-20 EP disclosed
EP-1879599-A2 METHODS, COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR ENHANCING SURVIVABILITY OF CELLS, TISSUES, ORGANS, AND ORGANISMS Fred Hutchinson Cancer Research Center (US) 2008-01-23 EP disclosed
EP-1875926-A1 STABLE EMULSION COMPOSITION Takeda Pharmaceutical Company Limited (JP) 2008-01-09 EP disclosed
US-20070265223-A1 COMPOSITIONS AND METHODS OF ENHANCING SURVIVABILITY AND REDUCING INJURY OF CELLS, TISSUES, ORGANS, AND ORGANISMS UNDER HYPOXIC OR ISCHEMIC CONDITIONS IKARIA, INC. (US) 2007-11-15 US disclosed
WO-2007124447-A2 USE OF CHALCOGENIDES FOR TREATING SHOCK AND OTHER ADVERSE CONDITIONS FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2007-11-01 WO disclosed
US-7288654-B2 Fused-ring pyridine derivative, process for producing the same, and use TAKEDA PHARMACEUTICAL COMPANY LTD (JP) 2007-10-30 US disclosed
EP-1832588-A1 CONDENSED IMIDAZOLE COMPOUND AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2007-09-12 EP disclosed
EP-1829549-A1 AMORPHOUS COMPOSITION ONO PHARMACEUTICAL CO., LTD. (JP) 2007-09-05 EP disclosed
EP-1829534-A1 Use of compounds binding to the sigma receptor for the treatment of metabolic syndrome LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-09-05 EP disclosed
US-7262185-B2 Benzazepine derivative, process for producing the same, and use TAKEDA CHEMICAL INDUSTRIES LTD. (JP) 2007-08-28 US disclosed
US-20070197636-A1 Coumarin Derivative And Use Thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-08-23 US disclosed
WO-2007092717-A1 LATEX OR PSEUDOLATEX COMPOSITIONS COATINGS AND COATING PROCESSES FMC CORPORATION (US) 2007-08-16 WO disclosed
US-20070184102-A1 LATEX OR PSEUDOLATEX COMPOSITIONS, COATINGS AND COATING PROCESSES FMC CORPORATION (US) 2007-08-09 US disclosed
US-20070179154-A1 Coumarin derivatives, process for their production and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-08-02 US disclosed
US-20070166364-A1 Transdermal Therapeutic System BEIER CORNELIA 2007-07-19 US disclosed
US-20070166362-A1 Transdermal and transmucosal preparations KABUSHIKI KAISHA SANGI (JP) 2007-07-19 US disclosed
EP-1797900-A1 PREPARATION FOR PERCUTANEOUS/PERMUCOSAL ABSORPTION KABUSHIKI KAISHA SANGI (JP) 2007-06-20 EP disclosed
EP-1787679-A1 Use of compounds binding to the sigma receptor for the treatment of diabetes-associated pain LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-05-23 EP disclosed
US-7220473-B2 Storage stability HEXAL AG (DE) 2007-05-22 US disclosed
WO-2007047837-A2 (-)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE, COMPOSITIONS THEREOF, AND USES FOR TREATING ALCOHOL-RELATED DISORDERS DOV PHARMACEUTICAL, INC. (US) 2007-04-26 WO disclosed
US-20070078113-A1 Oxygen antagonists; reducing agent, preservatives; enhancing survivability and achieving stasis or pre-stasis in cells or tissues; organ transplantation, hyperthermia, wound healing, hemorrhagic shock, cardioplegia for bypass surgery, neurodegeneration, hypothermia, and cancer FRED HUTCHINSON CANCER RESEARCH CENTER 2007-04-05 US disclosed
US-7199124-B2 JNK inhibitor TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-04-03 US disclosed
CN-1901795-A Methods, compositions and devices for inducing stasis in cells, tissues, organs, and organisms HUTCHINSON FRED CANCER RES (US) 2007-01-24 CN disclosed
EP-1254659-B1 STABLE EMULSION COMPOSITIONS TAKEDA PHARMACEUTICAL (JP) 2006-11-15 EP disclosed
EP-1720850-A1 COUMARIN DERIVATIVE AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2006-11-15 EP disclosed
WO-2006113914-A2 METHODS, COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR ENHANCING SURVIVABILITY OF CELLS, TISSUES, ORGANS, AND ORGANISMS FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2006-10-26 WO disclosed
CN-1838969-A Preparation for percutaneous/permucosal absorption SANGI KK (JP) 2006-09-27 CN disclosed
US-7105572-B2 Stable emulsion compositions TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-09-12 US disclosed
EP-1689228-A2 METHODS, COMPOSITIONS AND DEVICES FOR INDUCING STASIS IN CELLS Fred Hutchinson Cancer Research Center (US) 2006-08-16 EP disclosed
US-20060178359-A1 Tricyclic compound, process for producing the same, and use SYNGENTA CROP PROTECTION AG (CH) 2006-08-10 US disclosed
US-20060173064-A1 (-)-1-(3,4-Dichlorophenyl)-3-azabi cyclo[3.1.0]hexane, compositions thereof, and uses for treating alcohol-related disorders LIPPA ARNOLD S 2006-08-03 US disclosed
EP-1684580-A2 METHODS, COMPOSITIONS AND DEVICES FOR INDUCING STASIS IN TISSUES AND ORGANS Fred Hutchinson Cancer Research Center (US) 2006-08-02 EP disclosed
EP-1684579-A1 METHODS, COMPOSITIONS AND DEVICES FOR INDUCING STASIS IN CELLS, TISSUES, ORGANS, AND ORGANISMS Fred Hutchinson Cancer Research Center (US) 2006-08-02 EP disclosed
US-20060160864-A1 Acrylamide derivative, process for producing the same, and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-07-20 US disclosed
EP-1338288-B1 CELLULOSIC PARTICLES FOR PHARMACEUTICAL PREPARATIONS ASAHI CHEMICAL IND (JP) 2006-05-31 EP disclosed
US-20060100197-A1 Fused-ring pyridine derivative, process for producing the same, and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-05-11 US disclosed
CN-1255194-C Pharmaceutical administration form MUELLER D (DE) 2006-05-10 CN disclosed
EP-1641446-A1 PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF Pediamed Pharmaceuticals, Inc. (US) 2006-04-05 EP disclosed
US-20060058288-A1 Severe sepsis preventive therapeutic agent TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2006-03-16 US disclosed
US-20060035865-A1 Lipid-rich plaque regressing agents TERASHITA ZEN-ICHI 2006-02-16 US disclosed
US-6974806-B2 Lipid-rich plaque inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-12-13 US disclosed
EP-1593680-A1 FUSED-RING PYRIDINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Pharmaceutical Company Limited (JP) 2005-11-09 EP disclosed
EP-1593673-A1 ACRYLAMIDE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Pharmaceutical Company Limited (JP) 2005-11-09 EP disclosed
EP-1593681-A1 TRICYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Pharmaceutical Company Limited (JP) 2005-11-09 EP disclosed
US-20050245537-A1 Use of compounds having ccr antagonism TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-11-03 US disclosed
CN-1222318-C Cellulosic particle for pharmaceutical preparation ASAHI CHEMICAL IND (JP) 2005-10-12 CN disclosed
WO-2005082879-A1 COUMARIN DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-09-09 WO disclosed
EP-1154776-B1 PHARMACEUTICAL COMPOSITION CONTAINING DESOXYPEGANINE FOR THE TREATMENT OF ALCOHOLISM HF ARZNEIMITTELFORSCH GMBH (DE) 2005-08-17 EP disclosed
US-20050170019-A1 Methods, compositions and devices for inducing stasis in cells FRED HUTCHINSON CANCER RESEARCH CENTER 2005-08-04 US disclosed
US-20050147692-A1 Methods, compositions and devices for inducing stasis in tissues and organs FRED HUTCHINSON CANCER RESEARCH CENTER 2005-07-07 US disclosed
US-20050136125-A1 Methods, compositions and devices for inducing stasis in cells, tissues, organs, and organisms NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-06-23 US disclosed
WO-2005041655-A1 METHODS, COMPOSITIONS AND DEVICES FOR INDUCING STASIS IN CELLS, TISSUES, ORGANS, AND ORGANISMS FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2005-05-12 WO disclosed
WO-2005041656-A2 METHODS, COMPOSITIONS AND DEVICES FOR INDUCING STASIS IN TISSUES AND ORGANS FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2005-05-12 WO disclosed
WO-2005039291-A2 METHODS, COMPOSITIONS AND DEVICES FOR INDUCING STASIS IN CELLS FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2005-05-06 WO disclosed
US-20050080113-A1 Medicinal compositions TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-04-14 US disclosed
US-20050020634-A1 Coumarin derivatives, process for their production and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-01-27 US disclosed
EP-1498125-A1 USE OF COMPOUNDS HAVING CCR ANTAGONISM Takeda Pharmaceutical Company Limited (JP) 2005-01-19 EP disclosed
EP-1495756-A1 SEVERE SEPSIS PREVENTIVE THERAPEUTIC AGENT Takeda Chemical Industries, Ltd. (JP) 2005-01-12 EP disclosed
WO-2004112771-A1 PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF PEDIAMED PHARMACEUTICALS, INC. (US) 2004-12-29 WO disclosed
US-20040259809-A1 Pharmaceutical compositions including an antihistamine and a stimulant and method of use thereof PEDIAMED PHARMACEUTICALS, INC. 2004-12-23 US disclosed
US-20040259876-A1 Bicyclic compound, production and use thereof TOBIRA THERAPEUTICS, INC. 2004-12-23 US disclosed
US-20040253276-A1 Stable emulsion composition TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-12-16 US disclosed
US-20040235822-A1 Benzazepine derivative, process for producing the same, and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-11-25 US disclosed
EP-1471064-A1 COUMARIN DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2004-10-27 EP disclosed
EP-1423376-A1 BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2004-06-02 EP disclosed
EP-1420783-A1 STABLE EMULSION COMPOSITION Takeda Chemical Industries, Ltd. (JP) 2004-05-26 EP disclosed
EP-1422228-A1 BENZAZEPINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Chemical Industries, Ltd. (JP) 2004-05-26 EP disclosed
US-20040097555-A1 Concomitant drugs TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-05-20 US disclosed
US-20040063685-A1 Cycloalkene antisepsis drug with antibacterial, antifungal, nonsteroidal antiinflammatory, steroid and/or anticoagulant agents TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-04-01 US disclosed
US-20040063946-A1 Jnk inhibitor TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-04-01 US disclosed
EP-1402900-A1 MEDICINAL COMPOSITIONS Takeda Chemical Industries, Ltd. (JP) 2004-03-31 EP disclosed
US-20040053973-A1 Substituted 1,3-thiazole compounds, their production and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-03-18 US disclosed
US-20040047901-A1 Storage stability HEXAL AG (DE) 2004-03-11 US disclosed
US-20040043964-A1 Cellulosic particle for pharmaceuticals preparation ASAHI KASEI KABUSHIKI KAISHA (JP) 2004-03-04 US disclosed
CN-1473054-A Cellulose particles for pharmaceutical preparations ������������ʽ���� 2004-02-04 CN disclosed
US-20030232809-A1 Lipid-rich plaque inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2003-12-18 US disclosed
EP-1364949-A1 JNK INHIBITOR Takeda Chemical Industries, Ltd. (JP) 2003-11-26 EP disclosed
WO-2003014105-A9 BICYCLIC COMPOUND, PRODUCTION AND USE AS HIV INHIBITORS TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-11-20 WO disclosed
US-20030212114-A1 Stable emulsion compositions TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2003-11-13 US disclosed
EP-1354603-A1 CONCOMITANT DRUGS Takeda Chemical Industries, Ltd. (JP) 2003-10-22 EP disclosed
EP-1348443-A1 COMBINATION DRUGS Takeda Chemical Industries, Ltd. (JP) 2003-10-01 EP disclosed
US-6627631-B1 Desoxypeganine and its pharmaceutically acceptable acid addition salts can be used in the treatment of alcoholism. Said substances are administered preferably in a continuous and controlled manner. The pharmaceutical administration form LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2003-09-30 US disclosed
EP-1338288-A1 CELLULOSIC PARTICLE FOR PHARMACEUTICAL PREPARATION Asahi Kasei Kabushiki Kaisha (JP) 2003-08-27 EP disclosed
EP-1302470-A1 LIPID-RICH PLAQUE INHIBITORS Takeda Chemical Industries, Ltd. (JP) 2003-04-16 EP disclosed
WO-2003013513-A1 STABLE EMULSION COMPOSITION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-02-20 WO disclosed
WO-2003014105-A1 BICYCLIC COMPOUND, PRODUCTION AND USE AS HIV INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-02-20 WO disclosed
EP-1268474-A2 SUBSTITUTED 1,3-THIAZOLE COMPOUNDS, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 2003-01-02 EP disclosed
EP-1254659-A1 STABLE EMULSION COMPOSITIONS Takeda Chemical Industries, Ltd. (JP) 2002-11-06 EP disclosed
US-6413463-B1 GELATION OF WATER-SOLUBLE CELLULOSE DERIVATIVE IN TEMPERATURE REGION WHERE THE JELLY SHOWS LITTLE CHANGE IN VISCOSITY; UNIFORM; RECYCLING MATERIALS; DRUGS, FOODS, FERTILIZERS SHIONOGI QUALICAPS CO., LTD. (JP) 2002-07-02 US disclosed
EP-1154776-A1 PHARMACEUTICAL COMPOSITION CONTAINING DESOXYPEGANINE FOR THE TREATMENT OF ALCOHOLISM LTS Lohmann Therapie-Systeme AG (DE) 2001-11-21 EP disclosed
WO-2001074811-A2 SUBSTITUTED 1,3-THIAZOLE COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-10-11 WO disclosed
EP-1044682-A1 PROCESS FOR PRODUCING HARD CAPSULE Shionogi Qualicaps Co., Ltd. (JP) 2000-10-18 EP disclosed
WO-2000048600-A1 PHARMACEUTICAL COMPOSITION CONTAINING DESOXYPEGANINE FOR THE TREATMENT OF ALCOHOLISM LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2000-08-24 WO disclosed
US-5932238-A Galanthamine containing transdermal applicator for the treatment of alcoholism LTS LOHMANN THERAPIE-SYSTEME GMBH & CO. (DE) 1999-08-03 US disclosed
CN-1224366-A Pharmaceutical administration form MUELLER D (DE) 1999-07-28 CN disclosed
EP-0907388-A1 PHARMACEUTICAL ADMINISTRATION FORM Müller, Dieter (DE) 1999-04-14 EP disclosed
US-5830497-A Medicated plaster containing basic physiologically active agents and/or salts thereof NITTO DENKO CORPORATION (JP) 1998-11-03 US disclosed
WO-1998000198-A1 PHARMACEUTICAL ADMINISTRATION FORM MUELLER DIETER (DE) 1998-01-08 WO disclosed
US-5519017-A REDUCTION OF DESIRE FOR ALCOHOL BY ADMINISTERING GALANTHAMINE LTS LOHMANN THERAPIE-SYSTEME GMBH + CO. KG (DE) 1996-05-21 US disclosed
EP-0452837-B1 Adhesive device for transdermal administration of an active agent NITTO DENKO CORP (JP) 1995-08-16 EP disclosed
EP-0449247-B1 Pharmaceutical composition containing Galanthamine for treating alcoholism LOHMANN THERAPIE SYST LTS (DE) 1994-07-20 EP disclosed
EP-0387751-B1 Medicated plasters NITTO DENKO CORP (JP) 1994-06-08 EP disclosed
US-5192552-A Capsules coated with ethyl cellulose and sulfosuccinate in cyclohexane EGIS GYOGYSZERGYAR (HU) 1993-03-09 US disclosed
US-5176916-A Plaster layer containing a medicinal ingredient, hydrophobic polymer, absorption promoter, water and a hydrophilic polymer NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1993-01-05 US disclosed
EP-0452837-A2 Adhesive device for transdermal administration of an active agent NITTO DENKO CORPORATION (JP) 1991-10-23 EP disclosed
EP-0449247-A2 Pharmaceutical composition containing Galanthamine for treating alcoholism LTS Lohmann Therapie-Systeme GmbH & Co. KG (DE) 1991-10-02 EP disclosed
EP-0143603-B1 SUGAR-COATED PHARMACEUTICAL COMPOSITION AND METHOD FOR PREPARING THE SAME Dainippon Pharmaceutical Co., Ltd. (JP) 1990-10-31 EP disclosed
EP-0387751-A2 Medicated plasters NITTO DENKO CORPORATION (JP) 1990-09-19 EP disclosed
EP-0251904-B1 PROCESS FOR THE PREPARATION OF ACIDIC LEVOMEPROMAZINE MALEATE RHONE-POULENC SANTE (FR) 1990-01-10 EP disclosed
US-4798895-A Process for preparing levomepromazine hydrogen maleate RHONE-POULENC SANTE (FR) 1989-01-17 US disclosed
US-4798895-A Process for preparing levomepromazine hydrogen maleate RHONE-POULENC SANTE (FR) 1989-01-17 US disclosed
US-4798895-A Process for preparing levomepromazine hydrogen maleate RHONE-POULENC SANTE (FR) 1989-01-17 US disclosed
EP-0251904-A1 Process for the preparation of acidic levomepromazine maleate RHONE-POULENC SANTE (FR) 1988-01-07 EP disclosed
US-4650666-A DISCOLORATION INHIBITION DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1987-03-17 US disclosed
EP-0143603-A2 Sugar-coated pharmaceutical composition and method for preparing the same Dainippon Pharmaceutical Co., Ltd. (JP) 1985-06-05 EP disclosed
EP-0143603-A2 Sugar-coated pharmaceutical composition and method for preparing the same Dainippon Pharmaceutical Co., Ltd. (JP) 1985-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160250238-A1 Method for the Prophylaxis or Treatment of Systemic Lupus Erythematosus and/or Lupus Nephritis SSB, ME1, SLC16A1 DRD3 3667/4885DRD2 4292/4885DRD4 4436/4885
US-20250288541-A1 BINGE BEHAVIOR REGULATORS GABRB3, GABRB2, GABRB1 DRD3 131/4885DRD2 62/4885DRD4 106/4885
US-20040259876-A1 Bicyclic compound, production and use thereof CCR5, CCR1, CCR2 DRD3 271/4885DRD2 383/4885DRD4 525/4885
US-20160311811-A1 HETEROCYCLIC COMPOUND IRAK4, IRAK1, IRAK2 DRD3 3746/4885DRD2 3670/4885DRD4 2044/4885
US-20090030032-A1 Bicyclic Compound, Production and Use Thereof CCR5, CCR1, CCR2 DRD3 434/4885DRD2 467/4885DRD4 561/4885
US-10738004-B2 Cyclic compound TLR4, TLR3, TLR1 DRD3 3986/4885DRD2 3795/4885DRD4 3810/4885
US-10053468-B2 Heterocyclic compound RORC, RORB, RORA DRD3 1553/4885DRD2 2013/4885DRD4 1753/4885
US-20170050974-A1 HETEROCYCLIC COMPOUND RORC, RORB, RORA DRD3 1553/4885DRD2 2013/4885DRD4 1753/4885
US-20180085326-A1 BINGE BEHAVIOR REGULATORS GABRB3, GABRB2, GABRB1 DRD3 131/4885DRD2 62/4885DRD4 106/4885
US-20210046044-A1 USE OF (+)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE TO TREAT ADDICTIVE AND ALCOHOL-RELATED DISORDERS ADH1C, ADH1A, ADH5 DRD3 9/4885DRD2 5/4885DRD4 12/4885
US-10745397-B2 1-Substituted 1,2,3,4-tetrahydro-1,7-naphthyridin-8-amine derivatives and their use as EP4 receptor antagonists PTGER4, PTGER1, PTGER3 DRD3 657/4885DRD2 496/4885DRD4 395/4885
US-20230242529-A1 HETEROCYCLIC COMPOUND XIAP, BIRC5, BIRC3 DRD3 4061/4885DRD2 4349/4885DRD4 3786/4885
US-20140163001-A1 HETEROCYCLIC COMPOUND RORC, RORB, RORA DRD3 831/4885DRD2 942/4885DRD4 1347/4885
US-20050020634-A1 Coumarin derivatives, process for their production and use thereof CBR1, ACAT2, CBR3 DRD3 4551/4885DRD2 4802/4885DRD4 4689/4885
US-20200339577-A1 1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS PTGER4, PTGER1, PTGER3 DRD3 657/4885DRD2 496/4885DRD4 395/4885
US-10093629-B2 Heterocyclic compounds and their use as retinoid-related orphan receptor (ROR) gamma-T inhibitors RORC, RORB, RORA DRD3 2011/4885DRD2 2984/4885DRD4 2899/4885
US-20050080113-A1 Medicinal compositions TNF, TRAF6, MMP8 DRD3 4571/4885DRD2 4765/4885DRD4 4793/4885
US-20160361356-A1 METHODS, COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR ENHANCING SURVIVABILITY OF CELLS, TISSUES, ORGANS, AND ORGANISMS BCL2, BAX, HSF1 DRD3 4558/4885DRD2 3981/4885DRD4 4676/4885
US-20170174682-A1 HETEROCYCLIC COMPOUND JAK2, JAK1, STAT3 DRD3 4044/4885DRD2 4343/4885DRD4 4786/4885
US-20160251352-A1 HETEROCYCLIC COMPOUND JAK2, JAK1, STAT3 DRD3 4255/4885DRD2 4477/4885DRD4 4802/4885
US-20180099000-A1 Method for the Prophylaxis or Treatment of Systemic Lupus Erythematosus and/or Lupus Nephritis SSB, ME1, SLC16A1 DRD3 3767/4885DRD2 4364/4885DRD4 4484/4885
US-20060035865-A1 Lipid-rich plaque regressing agents NR1H2, NR1H3, LDLR DRD3 1873/4885DRD2 2544/4885DRD4 2656/4885
US-20040063685-A1 Cycloalkene antisepsis drug with antibacterial, antifungal, nonsteroidal antiinflammatory, steroid and/or anticoagulant agents ELANE, MMP8, SERPINC1 DRD3 2310/4885DRD2 3102/4885DRD4 3688/4885
US-20150094296-A1 HETEROCYCLIC COMPOUND TYK2, SSB, UACA DRD3 2798/4885DRD2 3116/4885DRD4 4213/4885
US-20080171725-A1 Oxygen antagonists; reducing agent, preservatives; enhancing survivability and achieving stasis or pre-stasis in cells or tissues; organ transplantation, hyperthermia, wound healing, hemorrhagic shock, cardioplegia for bypass surgery, neurodegeneration, hypothermia, and cancer HSF1, BCL2, HSP90AB1 DRD3 3521/4885DRD2 1650/4885DRD4 3273/4885
US-20030212114-A1 Stable emulsion compositions AHR, NR1H2, NR1H3 DRD3 477/4885DRD2 283/4885DRD4 1115/4885
US-12084436-B2 Heterocyclic compound HDAC1, HDAC5, HDAC6 DRD3 3266/4885DRD2 3691/4885DRD4 3354/4885
US-20170144973-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE AS RETINOID-RELATED ORPHAN RECEPTOR (ROR) GAMMA-T INHIBITORS RORC, RORB, RORA DRD3 2011/4885DRD2 2984/4885DRD4 2899/4885
US-20170216251-A1 USE OF (+)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE TO TREAT ADDICTIVE AND ALCOHOL-RELATED DISORDERS ADH1C, ADH1A, ADH5 DRD3 9/4885DRD2 5/4885DRD4 12/4885
US-20080167314-A1 Condensed Imidazole Compound And Use Thereof MAPK13, MMP13, MAPK3 DRD3 2807/4885DRD2 4157/4885DRD4 3236/4885
US-20120232028-A1 Bicyclic Compound, Production and Use Thereof CCR5, CCR1, CCR2 DRD3 434/4885DRD2 467/4885DRD4 561/4885
US-20090105314-A1 Pharmaceutical Agent TLR1, TLR6, TPMT DRD3 4544/4885DRD2 4399/4885DRD4 4668/4885
US-20050147692-A1 Methods, compositions and devices for inducing stasis in tissues and organs HIF1A, HIF1AN, PYGL DRD3 3743/4885DRD2 2994/4885DRD4 4495/4885
US-20220033371-A1 DP ANTAGONIST OPRL1, CNR1, NPSR1 DRD3 216/4885DRD2 116/4885DRD4 393/4885
US-20110065628-A1 Medication Combinations for the Treatment of Alcoholism and Drug Addiction SLC6A3, SLC6A4, ADH5 DRD3 17/4885DRD2 11/4885DRD4 15/4885
US-20040053973-A1 Substituted 1,3-thiazole compounds, their production and use MAPK1, MAP4K2, MAPK4 DRD3 3757/4885DRD2 4252/4885DRD4 3903/4885
US-20090011051-A1 Methods, Compositions and Articles of Manufacture for HIF Modulating Compounds HIF1A, HIF1AN, EGLN3 DRD3 4871/4885DRD2 4867/4885DRD4 4869/4885
US-11453661-B2 Heterocyclic compound HDAC6, HDAC1, HDAC5 DRD3 3221/4885DRD2 3705/4885DRD4 3630/4885
US-20170105969-A1 CENICRIVIROC FOR THE TREATMENT OF HIV-2 INFECTION CCR5, CCR2, CCR1 DRD3 2506/4885DRD2 2674/4885DRD4 3667/4885
US-10435399-B2 HDAC6 inhibitory heterocyclic compound HDAC6, HDAC1, HDAC5 DRD3 3361/4885DRD2 3864/4885DRD4 3746/4885
US-20170107240-A1 AMIDE COMPOUND RORB, RORC, RORA DRD3 2546/4885DRD2 2678/4885DRD4 2750/4885
US-20070078113-A1 Oxygen antagonists; reducing agent, preservatives; enhancing survivability and achieving stasis or pre-stasis in cells or tissues; organ transplantation, hyperthermia, wound healing, hemorrhagic shock, cardioplegia for bypass surgery, neurodegeneration, hypothermia, and cancer HSF1, BCL2, HSP90AB1 DRD3 3521/4885DRD2 1650/4885DRD4 3273/4885
US-20180319812-A1 HETEROCYCLIC COMPOUND RORC, RORB, RORA DRD3 1553/4885DRD2 2013/4885DRD4 1753/4885
US-20160229814-A1 HETEROCYCLIC COMPOUND RORB, RORC, RORA DRD3 1532/4885DRD2 1522/4885DRD4 1806/4885
US-20080171726-A1 oxygen antagonists; reducing agent, preservatives; enhancing survivability and achieving stasis or pre-stasis in biological materials (cells, tissues); organ transplantation, hyperthermia, wound healing, hemorrhagic shock, cardioplegia for bypass surgery, neurodegeneration, hypothermia, and cancer HSF1, HSP90AB1, HSP90AA1 DRD3 3950/4885DRD2 2115/4885DRD4 3843/4885
US-20050136125-A1 Methods, compositions and devices for inducing stasis in cells, tissues, organs, and organisms HSF1, HSP90AB1, HSP90AA1 DRD3 4719/4885DRD2 4261/4885DRD4 4850/4885
US-20100041689-A1 Combined Effects of Topiramate and Ondansetron on Alcohol Consumption SLC6A3, SLC6A4, HTR5A DRD3 28/4885DRD2 12/4885DRD4 25/4885
US-12350242-B2 Binge behavior regulators GABRB3, GABRB2, GABRB1 DRD3 131/4885DRD2 62/4885DRD4 106/4885
US-20090036529-A1 THERAPEUTIC AGENT FOR FUNCTIONAL BRAIN DISEASE PYGB, FABP7, GRIK5 DRD3 1191/4885DRD2 860/4885DRD4 2075/4885
US-20140037710-A1 METHOD FOR PRODUCING PATCH, AND PATCH DSG1, DSP, DSC1 DRD3 2646/4885DRD2 2839/4885DRD4 1820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.